-
1
-
-
33746897253
-
-
Zipfel PF, editor. Basel: Birkhäuser
-
Zipfel PF, editor. Complement and kidney diseases. Basel: Birkhäuser; 2006. This book covers and combines several in-depth aspects of defective complement in kidney disease, particularly in MPGN and HUS.
-
(2006)
Complement and Kidney Diseases
-
-
-
2
-
-
22544461682
-
Hemolytic uremic syndrome
-
Noris M, Remuzzi G. Hemolytic uremic syndrome. J Am Soc Nephrol 2005; 16:1035-1050. A recent and actual review which covers the broad aspects of complement regulation in various diseases.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 1035-1050
-
-
Noris, M.1
Remuzzi, G.2
-
3
-
-
31144460785
-
The central role of the alternative complement pathway in human disease
-
Thurman JM, Holers VM. The central role of the alternative complement pathway in human disease. J Immunol 2006; 176:1305-1310. A recent and timely review which demonstrates the role of complement regulation in various clinical settings and its association with a broad range of diseases.
-
(2006)
J Immunol
, vol.176
, pp. 1305-1310
-
-
Thurman, J.M.1
Holers, V.M.2
-
4
-
-
29744434906
-
Hemolytic uremic syndrome: An example of insufficient complement regulation on self-tissue
-
Atkinson JP, Liszewski MK, Richards A, et al. Hemolytic uremic syndrome: an example of insufficient complement regulation on self-tissue. Ann N Y Acad Sci 2005; 1056:144-152. A recent reviewwhich analyses the role of insufficient complement regulation in HUS.
-
(2005)
Ann N Y Acad Sci
, vol.1056
, pp. 144-152
-
-
Atkinson, J.P.1
Liszewski, M.K.2
Richards, A.3
-
5
-
-
17144365102
-
Hemolytic uremic syndrome: Pathogenesis, treatment, and outcome
-
Siegler R, Oakes R. Hemolytic uremic syndrome: pathogenesis, treatment, and outcome. Curr Opin Pediatr 2005; 17:200-204.
-
(2005)
Curr Opin Pediatr
, vol.17
, pp. 200-204
-
-
Siegler, R.1
Oakes, R.2
-
6
-
-
22544431912
-
Complement and diseases: Defective alternative pathway control results in kidney and eye diseases
-
Zipfel PF, Heinen S, Jozsi M, Skerka C. Complement and diseases: defective alternative pathway control results in kidney and eye diseases. Mol Immunol 2006; 43:97-106. This review summarizes how mutations in genes coding for complement regulators cause kidney diseases and relate to age-related macular degeneration.
-
(2006)
Mol Immunol
, vol.43
, pp. 97-106
-
-
Zipfel, P.F.1
Heinen, S.2
Jozsi, M.3
Skerka, C.4
-
7
-
-
18844420498
-
Complement and glomerulonephritis: New insights
-
Thurnberg D, Cook TH. Complement and glomerulonephritis: new insights. Curr Opin Nephrol Hypertens 2005; 14:223-228.
-
(2005)
Curr Opin Nephrol Hypertens
, vol.14
, pp. 223-228
-
-
Thurnberg, D.1
Cook, T.H.2
-
8
-
-
33645562434
-
The role of defective complement control in haemolytic uraemic syndrome
-
Zipfel PF, Misselwitz J, Licht C, Skerka C. The role of defective complement control in haemolytic uraemic syndrome. Semin Thromb Hemost 2006; 32:146-154.
-
(2006)
Semin Thromb Hemost
, vol.32
, pp. 146-154
-
-
Zipfel, P.F.1
Misselwitz, J.2
Licht, C.3
Skerka, C.4
-
9
-
-
0031970553
-
Genetic studies into inherited and sporadic hemolytic uremic syndrome
-
Warwicker P, Goodship TH, Donne RL. Genetic studies into inherited and sporadic hemolytic uremic syndrome. Kidney Int 1998; 53:836-844.
-
(1998)
Kidney Int
, vol.53
, pp. 836-844
-
-
Warwicker, P.1
Goodship, T.H.2
Donne, R.L.3
-
10
-
-
0035121908
-
Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome
-
Perez-Caballero D, Gonzalez-Rubio C, Gallardo ME, et al. Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome. Am J Hum Genet 2001; 68:478-484.
-
(2001)
Am J Hum Genet
, vol.68
, pp. 478-484
-
-
Perez-Caballero, D.1
Gonzalez-Rubio, C.2
Gallardo, M.E.3
-
11
-
-
0035143299
-
The molecular basis of familial hemolytic uremic syndrome: Mutation analysis of factor H gene reveals a hot spot in short consensus repeat 20
-
Caprioli J, Bettinaglio P, Zipfel PF, et al. The molecular basis of familial hemolytic uremic syndrome: mutation analysis of factor H gene reveals a hot spot in short consensus repeat 20. J Am Soc Nephrol 2001; 12:297-307.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 297-307
-
-
Caprioli, J.1
Bettinaglio, P.2
Zipfel, P.F.3
-
12
-
-
0042329931
-
Haemolytic uraemic syndrome and mutations of the factor H gene: A registry-based study of German speaking countries
-
Neumann HP, Salzmann M, Bohnert-Iwan B, et al. Haemolytic uraemic syndrome and mutations of the factor H gene: a registry-based study of German speaking countries. J Med Genet 2003; 40:676-681.
-
(2003)
J Med Genet
, vol.40
, pp. 676-681
-
-
Neumann, H.P.1
Salzmann, M.2
Bohnert-Iwan, B.3
-
13
-
-
0242331610
-
Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome
-
USA
-
Richards A, Kemp EJ, Liszewski MK, et al. Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome. Proc Natl Acad Sci USA 2003; 100:12966-12971.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 12966-12971
-
-
Richards, A.1
Kemp, E.J.2
Liszewski, M.K.3
-
14
-
-
0242570482
-
Familial haemolytic uraemic syndrome and an MCP mutation
-
Noris M, Brioschi S, Caprioli J, et al. Familial haemolytic uraemic syndrome and an MCP mutation. Lancet 2003; 362:1542-1547.
-
(2003)
Lancet
, vol.362
, pp. 1542-1547
-
-
Noris, M.1
Brioschi, S.2
Caprioli, J.3
-
15
-
-
33644964155
-
Insights into hemolytic uremic syndrome: Segregation of three independent predisposition factors in large, multiple affected pedigree
-
Esparza-Gordillo J, Goicoechea de Jorge E, et al. Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in large, multiple affected pedigree. Mol Immunol 2006; 43:1769-1775.
-
(2006)
Mol Immunol
, vol.43
, pp. 1769-1775
-
-
Esparza-Gordillo, J.1
Goicoechea De Jorge, E.2
-
16
-
-
19444369542
-
Complement factor I: A susceptibility gene for atypical haemolytic uraemic syndrome
-
Fremeaux-Bacchi V, Dragon-Durey MA, Blouin J, et al. Complement factor I: a susceptibility gene for atypical haemolytic uraemic syndrome. J Med Genet 2004; 41:e84.
-
(2004)
J Med Genet
, vol.41
-
-
Fremeaux-Bacchi, V.1
Dragon-Durey, M.A.2
Blouin, J.3
-
17
-
-
27744452766
-
Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome
-
Kavanagh D, Kemp EJ, Mayland E, et al. Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome. J Am Soc Nephrol 2005; 16:2150-2155. Extends the recent findings of Femaux Bacchi et al. and identifies the frequency of factor I gene mutations in HUS.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2150-2155
-
-
Kavanagh, D.1
Kemp, E.J.2
Mayland, E.3
-
18
-
-
33644870779
-
Phenotypic expression of factor H mutations inpatients with atypical haemolytic uremic syndrome
-
Vaziri-Sani F, Holmberg L, Sjoholm AG, et al. Phenotypic expression of factor H mutations inpatients with atypical haemolytic uremic syndrome. Kidney Int 2006; 69:981-988.
-
(2006)
Kidney Int
, vol.69
, pp. 981-988
-
-
Vaziri-Sani, F.1
Holmberg, L.2
Sjoholm, A.G.3
-
19
-
-
10044233893
-
Activation of the complement system generates antibacterial peptides
-
USA
-
Nordahl EA, Rydengard V, Nyberg P, et al. Activation of the complement system generates antibacterial peptides. Proc Natl Acad Sci USA 2004; 101:16879-16884.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 16879-16884
-
-
Nordahl, E.A.1
Rydengard, V.2
Nyberg, P.3
-
20
-
-
0034968528
-
Complement factor H: Physiology and pathophysiology
-
Zipfel PF. Complement factor H: physiology and pathophysiology. Semin Thromb Hemost 2001; 27:191-199.
-
(2001)
Semin Thromb Hemost
, vol.27
, pp. 191-199
-
-
Zipfel, P.F.1
-
21
-
-
2442433542
-
The human complement factor H: Functional roles, genetic variations and disease associations
-
Rodriguez de Cordoba S, Esparza-Gordillo J, Goicoechea de Jorge E, et al. The human complement factor H: functional roles, genetic variations and disease associations. Mol Immunol 2004; 41:355-367.
-
(2004)
Mol Immunol
, vol.41
, pp. 355-367
-
-
Rodriguez De Cordoba, S.1
Esparza-Gordillo, J.2
Goicoechea De Jorge, E.3
-
22
-
-
0037396993
-
Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome
-
Manuelian T, Hellwage J, Meri S, et al. Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome. J Clin Invest 2003; 111:1181-1190.
-
(2003)
J Clin Invest
, vol.111
, pp. 1181-1190
-
-
Manuelian, T.1
Hellwage, J.2
Meri, S.3
-
23
-
-
26244435599
-
Binding of complement factor H to endothelial cells is mediated by the carboxy-terminal glycosaminoglycan binding site
-
Jokiranta TS, Cheng ZZ, Seeberger H, et al. Binding of complement factor H to endothelial cells is mediated by the carboxy-terminal glycosaminoglycan binding site. Am J Pathol 2005; 167:1173-1181. This manuscript shows that the C-terminus of factor H mediates recognition functions and binding to endothelial cells.
-
(2005)
Am J Pathol
, vol.167
, pp. 1173-1181
-
-
Jokiranta, T.S.1
Cheng, Z.Z.2
Seeberger, H.3
-
24
-
-
33645558126
-
Role of complement and factor H in haemolytic uraemic syndrome
-
Zipfel PF, editor. Basel: Birkhäuser
-
Skerka C, Józsi M. Role of complement and factor H in haemolytic uraemic syndrome. In: Zipfel PF, editor. Complement and kidney diseases. Basel: Birkhäuser; 2006. pp. 85-109.
-
(2006)
Complement and Kidney Diseases
, pp. 85-109
-
-
Skerka, C.1
Józsi, M.2
-
25
-
-
29944439131
-
An interactive web database of factor H associated hemolytic uremic syndrome mutations: Insights into the structural consequences of disease-associated mutations
-
Saunders RE, Goodship TH, Zipfel PF, Perkins SJ. An interactive web database of factor H associated hemolytic uremic syndrome mutations: insights into the structural consequences of disease-associated mutations. Hum Mutat 2006; 27:21-30. This group in London has generated an interactive web database which summarizes all reported factor H gene mutations and the structural consequences of the individual mutations. It is of interest to the community to keep the database active in order to use it as a valuable resource for mutation analysis.
-
(2006)
Hum Mutat
, vol.27
, pp. 21-30
-
-
Saunders, R.E.1
Goodship, T.H.2
Zipfel, P.F.3
Perkins, S.J.4
-
26
-
-
33645451557
-
Factor H and atypical hemolytic uremic syndrome: Mutations in the C-terminus cause structural changes and defective recognition functions
-
Jozsi M, Heinen S, Hartmann A, et al. Factor H and atypical hemolytic uremic syndrome: mutations in the C-terminus cause structural changes and defective recognition functions. J Am Soc Nephrol 2006; 17:170-177. The authors show that all seven analyzed HUS-associated mutations of factor H located in the C-terminal domains 19 and 20 affect recognition functions.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 170-177
-
-
Jozsi, M.1
Heinen, S.2
Hartmann, A.3
-
29
-
-
29144497930
-
Does complement factor B have a role in the pathogenesis of atypical HUS?
-
Kavanagh D, Kemp EJ, Richards A, et al. Does complement factor B have a role in the pathogenesis of atypical HUS? Mol Immunol 2006; 43:856-859. This study excludes the complement regulator factor B from the list of HUS candidate genes.
-
(2006)
Mol Immunol
, vol.43
, pp. 856-859
-
-
Kavanagh, D.1
Kemp, E.J.2
Richards, A.3
-
30
-
-
14644424005
-
Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32
-
Esparza-Gordillo J, Goicoechea de Jorge E, Buil A, et al. Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32. Hum Mol Genet 2005; 14:703-712.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 703-712
-
-
Esparza-Gordillo, J.1
Goicoechea De Jorge, E.2
Buil, A.3
-
31
-
-
26944480588
-
The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: Evidence from two independent cohorts
-
Fremeaux-Bacchi V, Kemp EJ,Goodship JA, et al. The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: evidence from two independent cohorts. J Med Genet 2005; 42:852-856.
-
(2005)
J Med Genet
, vol.42
, pp. 852-856
-
-
Fremeaux-Bacchi, V.1
Kemp, E.J.2
Goodship, J.A.3
-
32
-
-
0242601270
-
Complement factor H mutations and gene polymorphisms in haemolytic uraemic syndrome: The C-257T, the A2089G and the G2881T polymorphisms are strongly associated with the disease
-
Caprioli J, Castelletti F, Bucchioni S, et al. Complement factor H mutations and gene polymorphisms in haemolytic uraemic syndrome: the C-257T, the A2089G and the G2881T polymorphisms are strongly associated with the disease. Hum Mol Genet 2003; 12:3385-3395.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 3385-3395
-
-
Caprioli, J.1
Castelletti, F.2
Bucchioni, S.3
-
33
-
-
33746655453
-
De novo gene conversion in the RCA gene cluster (1q32) causes mutations in complement factor H associated with atypical hemolytic uremic syndrome
-
Heinen S, Sanchez-Corral P, Jackson MS, et al. De novo gene conversion in the RCA gene cluster (1q32) causes mutations in complement factor H associated with atypical hemolytic uremic syndrome. Hum Genetics 2006; 27:292-293.
-
(2006)
Hum Genetics
, vol.27
, pp. 292-293
-
-
Heinen, S.1
Sanchez-Corral, P.2
Jackson, M.S.3
-
34
-
-
0036900126
-
The molecular basis for hereditary porcine membranoproliferative glomerulonephritis type II: Point mutations in the factor H coding sequence block protein secretion
-
Hegasy GA, Manuelian T, Hogasen K, et al. The molecular basis for hereditary porcine membranoproliferative glomerulonephritis type II: point mutations in the factor H coding sequence block protein secretion. Am J Pathol 2002; 161:2027-2034.
-
(2002)
Am J Pathol
, vol.161
, pp. 2027-2034
-
-
Hegasy, G.A.1
Manuelian, T.2
Hogasen, K.3
-
35
-
-
20544437666
-
Anti-factor H autoantibodies associated with atypical hemolytic uremic syndrome
-
Dragon-Durey MA, Loirat C, Cloarec S, et al. Anti-factor H autoantibodies associated with atypical hemolytic uremic syndrome. J Am Soc Nephrol 2005; 16:555-563. The authors show a new aspect for the mechanisms of HUS. It is the first demonstration of autoantibodies in HUS and identifies a novel mechanism.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 555-563
-
-
Dragon-Durey, M.A.1
Loirat, C.2
Cloarec, S.3
-
36
-
-
33746870286
-
Complement defects in children which result in kidney diseases: Diagnosis and therapy
-
Zipfel PF, editor. Basel: Birkhäuser
-
Licht C, Hoppe B. Complement defects in children which result in kidney diseases: diagnosis and therapy. In: Zipfel PF, editor. Complement and kidney diseases. Basel: Birkhäuser; 2006. pp. 85-109.
-
(2006)
Complement and Kidney Diseases
, pp. 85-109
-
-
Licht, C.1
Hoppe, B.2
-
37
-
-
4344718851
-
Challenges in the management of infantile factor H associated hemolytic uremic syndrome
-
Filler G, Radhakrishnan S, Strain L, et al. Challenges in the management of infantile factor H associated hemolytic uremic syndrome. Pediatr Nephrol 2004; 19:908-911.
-
(2004)
Pediatr Nephrol
, vol.19
, pp. 908-911
-
-
Filler, G.1
Radhakrishnan, S.2
Strain, L.3
-
38
-
-
20144373025
-
Successful plasma therapy for atypical hemolytic uremic syndrome caused by factor H deficiency owing to a novel mutation in the complement cofactor protein domain 15
-
Licht C, Weyersberg A, Heinen S, et al. Successful plasma therapy for atypical hemolytic uremic syndrome caused by factor H deficiency owing to a novel mutation in the complement cofactor protein domain 15. Am J Kidney Dis 2005; 45:415-421.
-
(2005)
Am J Kidney Dis
, vol.45
, pp. 415-421
-
-
Licht, C.1
Weyersberg, A.2
Heinen, S.3
-
39
-
-
33745697887
-
Deletion of Lys224 in regulatory domain 4 of factor H reveals a novel pathomechanism for dense deposit disease (MPGNII)
-
12 April [Epub ahead of print]
-
Licht C, Heinen S, Jozsi M, et al. Deletion of Lys224 in regulatory domain 4 of factor H reveals a novel pathomechanism for dense deposit disease (MPGNII). Kidney Int 2006; 12 April [Epub ahead of print].
-
(2006)
Kidney Int
-
-
Licht, C.1
Heinen, S.2
Jozsi, M.3
-
40
-
-
33645569820
-
Membrane cofactor protein and factor I: Mutations and transplantation
-
Kavanagh D, Goodship TH. Membrane cofactor protein and factor I: mutations and transplantation. Semin Thromb Hemost 2006; 32:155-159.
-
(2006)
Semin Thromb Hemost
, vol.32
, pp. 155-159
-
-
Kavanagh, D.1
Goodship, T.H.2
-
41
-
-
20244377213
-
Hemolytic uremic syndrome: A fatal outcome after kidney and liver transplantation performed to correct factor H gene mutation
-
Remuzzi G, Ruggenenti P, Colledan M, et al. Hemolytic uremic syndrome: a fatal outcome after kidney and liver transplantation performed to correct factor H gene mutation. Am J Transplant 2005; 5:1146-1150.
-
(2005)
Am J Transplant
, vol.5
, pp. 1146-1150
-
-
Remuzzi, G.1
Ruggenenti, P.2
Colledan, M.3
-
42
-
-
1842637606
-
Attempted treatment of factor H deficiency by liver transplantation
-
Cheong HI, Lee BS, Kang HG, et al. Attempted treatment of factor H deficiency by liver transplantation. Pediatr Nephrol 2004; 19:454-458.
-
(2004)
Pediatr Nephrol
, vol.19
, pp. 454-458
-
-
Cheong, H.I.1
Lee, B.S.2
Kang, H.G.3
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