Blinded placebo crossover study of gabapentin in primary orthostatic tremor

Movement Disorders

Volumn 21, Issue 7, 2006, Pages 900-905

  Rodrigues, Julian P ^a,b   Edwards, Dylan J ^b,c   Walters, Susan E ^a   Byrnes, Michelle L ^b   Thickbroom, Gary W ^b   Stell, Rick ^a,d   Mastaglia, Frank L ^a,b,d  

^a Australian Neuromuscular Research Institute   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c EDITH COWAN UNIVERSITY   (Australia)

^d SIR CHARLES GAIRDNER HOSPITAL   (Australia)

Author keywords

Gabapentin; Orthostatic tremor; Postural stability; Quality of life; Static sway

Indexed keywords

BENSERAZIDE PLUS LEVODOPA; CLONAZEPAM; GABAPENTIN; PLACEBO; PRIMIDONE; PROPRANOLOL; VALPROIC ACID;

ABSENCE OF SIDE EFFECTS; ADD ON THERAPY; ADULT; AGED; ARTICLE; BODY EQUILIBRIUM; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISEASE SEVERITY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG ABSORPTION; DRUG EFFICACY; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; HUMAN; MALE; MOTOR DYSFUNCTION; PRIMARY ORTHOSTATIC TREMOR; PRIORITY JOURNAL; QUALITY OF LIFE; SELF CONCEPT; STABILOGRAPHY; SYMPTOMATOLOGY; TITRIMETRY; TREMOR;

AGED; AMINES; ANTIPARKINSON AGENTS; CROSS-OVER STUDIES; CYCLOHEXANECARBOXYLIC ACIDS; DIZZINESS; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; GAMMA-AMINOBUTYRIC ACID; HUMANS; MALE; MIDDLE AGED; MUSCULOSKELETAL EQUILIBRIUM; NEUROLOGIC EXAMINATION; POSTURAL BALANCE; QUALITY OF LIFE; RECURRENCE; SUBSTANCE WITHDRAWAL SYNDROME; TREMOR;

EID: 33746903493     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.20830     Document Type: Article

References (13)

1. Heilman KM. Orthostatic tremor. Arch Neurol 1984;41:880-881.
2. Thompson PD, Rothwell JC, Day BL, et al. The physiology of orthostatic tremor. Arch Neurol 1986;43:584-587.
3. Gerschlager W, Katzenschlager R, Schrag A, et al. Quality of life in patients with orthostatic tremor. J Neurol 2003;250:212-215.
4. Krauss JK, Capelle HH, Blahak C, Bazner H, Weigel R, Wohrle JC. Spinal cord stimulation in patients with primary orthostatic tremor. Mov Disord 2004;19(Suppl. 9):S288.
5. Evidente VG, Adler CH, Caviness JN, Gwinn KA. Effective treatment of orthostatic tremor with gabapentin. Mov Disord 1998;13: 829-831.
6. Onofrij M, Thomas A, Paci C, D'Andreamatteo G. Gabapentin in orthostatic tremor: results of a double-blind crossover with placebo in four patients. Neurology 1998;51:880-882.
7. Rodrigues JP, Edwards DJ, Walters SE, et al. Gabapentin can improve postural stability and quality of life in primary orthostatic tremor. Mov Disord 2005;20:865-870.
8. Peto V, Jenkinson C, Fitzpatrick R. PDQ-39: a review of the development, validation and application of a Parkinson's disease quality of life questionnaire and its associated measures. J Neurol 1998;245(Suppl. 1):S10-S14.
9. Carpenter MG, Frank JS, Winter DA, Peysar GW. Sampling duration effects on centre of pressure summary measures. Gait Posture 2001;13:35-40.
10. Yarrow K, Brown P, Gresty MA, Bronstein AM. Force platform recordings in the diagnosis of primary orthostatic tremor. Gait Posture 2001;13:27-34.
11. Fung VS, Sauner D, Day BL. A dissociation between subjective and objective unsteadiness in primary orthostatic tremor. Brain 2001;124(Pt. 2):322-330.
12. Bacsi AM, Halmagyi GM, Colebatch JG. Sway patterns in a case of orthostatic tremor responsive to alcohol. Mov Disord 2004;19: 1459-1463.
13. McManis PG, Sharbrough FW. Orthostatic tremor: clinical and electrophysiologic characteristics. Muscle Nerve 1993;16:1254-1260.