Pre-treatment of central venous catheters with the cathelicidin BMAP-28 enhances the efficacy of antistaphylococcal agents in the treatment of experimental catheter-related infection

Peptides

Volumn 27, Issue 9, 2006, Pages 2104-2110

  Cirioni, Oscar ^a   Giacometti, Andrea ^a   Ghiselli, Roberto ^a   Bergnach, Cristina ^b   Orlando, Fiorenza ^c   Mocchegiani, Federico ^a   Silvestri, Carmela ^a   Licci, Alberto ^a   Skerlavaj, Barbara ^b   Zanetti, Margherita ^b,d   Saba, Vittorio ^a   Scalise, Giorgio ^a  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^b UNIVERSITY OF UDINE   (Italy)

^c INRCA   (Italy)

^d Natl Lab CIB   (Italy)

Author keywords

Antibiotic lock technique; Antimicrobial peptides; Biofilm; BMAP 28; CVC

Indexed keywords

ANTIBIOTIC AGENT; CATHELICIDIN; DALFOPRISTIN PLUS QUINUPRISTIN; GLYCYLGLYCYLLEUCYLARGINYLSERYLLEUCYLGLYCYLARGINYLLYSYLISOLEUCYLLEUCYL ARGINYLALANYLTRYPTOPHANYLLYSYLLYSYLTYROSYLGLYCYLPROLYLISOLEUCYLISOLEUCYLVALYL PROLYLISOLEUCYLISOLEUCYLARGINYLISOLEUCINAMIDE; LINEZOLID; POLYPEPTIDE ANTIBIOTIC AGENT; SILASTIC; UNCLASSIFIED DRUG; VANCOMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTEREMIA; BACTERIAL CELL; BACTERIAL STRAIN; BIOFILM; CATHETER INFECTION; CELL ADHESION; CELL GROWTH; CENTRAL VENOUS CATHETER; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; IMPLANTATION; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; SUPERIOR CAVA VEIN;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CATHETERIZATION, CENTRAL VENOUS; DISEASE MODELS, ANIMAL; MALE; PROTEINS; RATS; RATS, WISTAR; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TREATMENT OUTCOME;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 33746900436     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2006.03.007     Document Type: Article

References (36)

1. Atela I., Coll P., Rello J., Barrio J., March F., Sanchez F., et al. Serial surveillance cultures of skin and catheter hub specimens from critically ill patients with central venous catheters: molecular epidemiology of infection and implications for clinical management and research. J Clin Microbiol 35 (1997) 1784-1790
2. Benincasa M., Skerlavaj B., Gennaro R., Pellegrini A., and Zanetti M. In vitro and in vivo antimicrobial activity of two alpha-helical cathelicidin peptides and of their synthetic analogs. Peptides 24 (2003) 1723-1731
3. Benoit J.L., Carandang G., Sitrin M., and Arnow P. Intraluminal antibiotic treatment of central venous catheter infections in patients receiving parenteral nutrition at home. Clin Infect Dis 24 (1997) 743-744
4. Buck M.A., Olah T.A., Weitzmann C.J., and Cooperman B.S. Protein estimation by the product of integrated peak area and flow rate. Anal Biochem 182 (1989) 295-299
5. Chen H., Zhang Z., Chen Y., Brook M.A., and Sheardown H. Protein repellant silicone surfaces by covalent immobilization of poly(ethylene oxide). Biomaterials 26 (2005) 2391-2399
6. Christensen G.D., Simpson W.A., Younger J.J., Baddour L.M., Barrett F.F., Melton D.M., et al. Adherence of coagulase-negative staphylococci to plastic tissue culture plates: a quantitative model for the adherence of staphylococci to medical devices. J Clin Microbiol 22 (1985) 996-1006
7. Clinical and Laboratory Standards Institute (CLSI). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: approved standard M7-A6 (2003), Clinical and Laboratory Standards Institute (CLSI), Villanova, PA
8. Costerton J.W., Stewart P.S., and Greenberg E.P. Bacterial biofilm: a common cause of persistent infections. Science 284 (1999) 1318-1322
9. Donlan R.M., and Costerton J.W. Biofilms: survival mechanisms of clinically relevant microorganisms. Clin Microbiol Rev 15 (2002) 167-193
10. Edelhoch H. Spectroscopic determination of tryptophan and tyrosine in proteins. Biochemistry 6 (1967) 1948-1954
11. Fux C.A., Costerton J.W., Stewart P.S., and Stoodley P. Survival strategies of infectious biofilm. Trends Microbiol 13 (2005) 34-40
12. Fux C.A., Stoodley P., Hall-Stoodley L., and Costerton J.W. Bacterial biofilms: a diagnostic and therapeutic challenge. Expert Rev Anti Infect Ther 1 (2003) 667-683
13. Giacometti A., Cirioni O., Ghiselli R., Bergnach C., Orlando F., D'Amato G., et al. The bovine antimicrobial peptide BMAP-28 reduces lethality due to bacterial cell wall components in mouse models of staphylococcal sepsis. Crit Care Med 32 (2004) 2485-2490
14. Hall-Stoodley L., Costerton J.W., and Stoodley P. Bacterial biofilms: from the natural environment to infectious diseases. Nat Rev Microbiol 2 (2004) 95-108
15. Hancock R.E.W. Peptides antibiotics. Lancet 349 (1997) 418-422
16. Hancock R.E.W. Cationic peptides: effectors in innate immunity and novel antimicrobials. Lancet Infect Dis 1 (2001) 156-164
17. Hancock R.E.W., and Chapple D.S. Peptide antibiotics. Antimicrob Agents Chemother 43 (1999) 1317-1323
18. Hannan M., Juste R.N., Umasanker S., Glendenning A., Nightingale C., Azadian B., et al. Antiseptic-bonded central venous catheters and bacterial colonization. Anaesthesia 54 (1999) 868-872
19. Harvey R.A., Alcid D.V., and Greco R.S. Antibiotic bonding to polytetrafluoroethylene with tridodecylmethylammonium chloride. Surgery 92 (1982) 504-512
20. Maki D.G. Infections caused by intravascular devices used for infusion therapy: pathogenesis, prevention and management. In: Bisno A.I., and Waldvogel F.A. (Eds). Infections associated with indwelling medical devices. 2nd ed. (2004), ASM Press, Washington, DC 155-212
21. Marciante K.D., Veenstra D.L., Lipsky B.A., and Saint S. Which antimicrobial impregnated central venous catheter should we us? Modeling the costs and outcomes of antimicrobial catheter use. Am J Infect Control 31 (2003) 1-8
22. McConnell S.A., Gubbins P.O., and Anaissie E.J. Do antimicrobial-impregnated central venous catheters prevent catheter-related bloodstream infection. Clin Infect Dis 37 (2003) 65-72
23. Mermel L.A., et al. Guidelines for the management of intravascular catheter-related infections. Clin Infect Dis 32 (2001) 1249-1272
24. Morra M., Cassinelli C., Cascardo G., Carpi A., Fini M., Giavaresi G., et al. Adsorption of cationic antibacterial on collagen-coated titanium implant devices. Biom Pharm 58 (2004) 428-432
25. Phaneuf M.D., Quist W.C., Bide M.J., and Lo Gerfo F.W. Modification of the polyethylene terephthalate (Dacron) via denier reduction: effects on material tensile strength, weight, and protein binding capabilities. J Appl Biomater 6 (1995) 289-299
26. Pittet D. Nosocomial bloodstream infections. In: Wenzel R.P. (Ed). Prevention and control of nosocomial infections. 3rd ed. (1997), Lippincott, Williams & Wilkins, Baltimore, MD 711-769
27. Raad I. Intravascular-catheter-related infection. Lancet 351 (1998) 893-898
28. Raad I., and Hanna H. Intravascular catheters impregnated with antimicrobial agents: a milestone in the prevention of bloodstream infections. Support Care Cancer 7 (1999) 386-390
29. Rupp M.E., Fey P.D., and Longo G.M. Effect of LY33328 against vancomycin-resistant Enterococcus faecium in a rat model central venous catheter-associated infection model. J Antimicrob Chemother 47 (2001) 705-707
30. Shorr A.F., Humphreys C.W., and Helman D.L. New choices for central venous catheters. Potential financial implications. Chest 124 (2003) 275-285
31. Skerlavaj B., Gennaro R., Bagella L., Merluzzi L., Risso A., and Zanetti M. Biological characterization of two novel cathelicidin-derived peptides and identification of structural requirements for their antimicrobial and cell lytic activities. J Biol Chem 71 (1996) 28375-28381
32. Stepanovic S., Vukovic D., Dakic I., Savic B., and Svabic-Vlahovic M. A modified microtiter-plate test for quantification of staphylococcal biofilm formation. J Microbiol Meth 40 (2000) 175-179
33. Yeaman M.R., and Yount N.Y. Mechanisms of antimicrobial peptide action and resistance. Pharm Rev 55 (2003) 27-55
34. Zanetti M. Cathelicidins, multifunctional peptides of the innate immunity. J Leuk Biol 75 (2004) 9-48
35. Zanetti M., Gennaro R., and Romeo D. Cathelicidins: a novel protein family with common proregion and a variable C-terminal antimicrobial domain. FEBS Lett 374 (1995) 1-5
36. Zanetti M., Gennaro R., Skerlavaj B., Tomasinsig L., and Circo R. Cathelicidin peptides as candidates for a novel class of antimicrobials. Curr Pharm Des 8 (2002) 779-793