Toward transplantation tolerance: A large step on a long road

American Journal of Transplantation

Volumn 6, Issue 9, 2006, Pages 1989-1990

  Newell, K A ^a   Larsen, C P ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN; MINOR HISTOCOMPATIBILITY ANTIGEN;

BONE MARROW TRANSPLANTATION; CHIMERA; EDITORIAL; HLA MATCHING; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; MULTIPLE MYELOMA; NONMYELOABLATIVE CONDITIONING; PRIORITY JOURNAL; TRANSPLANTATION TOLERANCE;

BONE MARROW TRANSPLANTATION; HUMANS; IMMUNE TOLERANCE; KIDNEY TRANSPLANTATION;

EID: 33746883183     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2006.01481.x     Document Type: Editorial

References (7)

1. Wekerle T, Kurtz J, Ito H et al. Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment. Nat Med 2000; 6: 464-469.
2. Kawai T, Cosimi AB, Wee SL et al. Effect of mixed hematopoietic chimerism on cardiac allograft survival in cynomolgus monkeys. Transplantation 2002; 73: 1757-1764.
3. Adams AB, Pearson TC, Larsen CP. Heterologous immunity: An overlooked barrier to tolerance. Immunol Rev 2003; 196: 147-160.
4. Buhler LH, Spitzer TR, Sykes M et al. Induction of kidney allograft tolerance after transient lymphohematopoietic chimerism in patients with multiple myeloma and end-stage renal disease. Transplantation 2002; 74: 1405-1409.
5. Jones ND, Turvey SE, Van Maurik A et al. Differential susceptibility of heart, skin, and islet allografts to T cell-mediated rejection. J Immunol 2001; 166: 2824-2830.
6. Ildstad ST, Wren SM, Bluestone JA, Barbieri SA, Sachs DH. Characterization of mixed allogeneic chimeras. Immunocompetence, in vitro reactivity, and genetic specificity of tolerance. J Exp Med 1985; 162: 231-244.
7. Kawai T, Sachs DH, Spitzer TR et al. Combined kidney and bone marrow transplantation for induction of mixed chimerism and renal allograft tolerance in HLAmatched and mismatched recipients. Am J Transplant 2005; (Suppl 11) 5: 546.