Clear cell hidradenoma of the skin - A third tumor type with a t(11;19)-associated TORC1-MAML2 gene fusion: Genes Chromosomes Cancer. 2005;43:202-205

Advances in Anatomic Pathology

Volumn 13, Issue 2, 2006, Pages 80-82

  El Naggar, Adel K ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; CHROMOSOME 11Q; CHROMOSOME 19P; CLEAR CELL CARCINOMA; CONTROLLED STUDY; GENE; GENE FUSION; GENE MUTATION; HIDRADENOMA; HUMAN; HUMAN TISSUE; MALE; MAML2 GENE; MOLECULAR CLONING; PRIORITY JOURNAL; REVIEW; TORC1 GENE; ARTICLE; CARCINOMA; CASE REPORT; DIFFERENTIAL DIAGNOSIS; GENE TRANSLOCATION; GENETICS; SENSITIVITY AND SPECIFICITY; SWEAT GLAND TUMOR;

DNA BINDING PROTEIN; MAML2 PROTEIN, HUMAN; NUCLEAR PROTEIN; TORC1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ADENOMA, SWEAT GLAND; AGED, 80 AND OVER; CARCINOMA; DIAGNOSIS, DIFFERENTIAL; DNA-BINDING PROTEINS; GENE FUSION; HUMANS; MALE; NUCLEAR PROTEINS; SENSITIVITY AND SPECIFICITY; SWEAT GLAND NEOPLASMS; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC;

EID: 33746880323     PISSN: 10724109     EISSN: 15334031     Source Type: Journal    
DOI: 10.1097/01.pap.0000213000.79866.bd     Document Type: Review

References (15)

1. Dahlenfors R, Lindahl L, Mark J. A fourth minor salivary gland mucoepidermoid carcinoma with 11q14-21 and 19p12 rearrangements. Hereditas. 1994;120:287-288.
2. Dahlenfors R, Wedell B, Rundcrantz H, et al. Translocation (11;19) (q′4-21;p12) in a parotid mucoepidermoid carcinoma of a child. Cancer Genet Cytogenet. 1995;79:188.
3. Nordkvist A, Gustafsson H, Juberg-Ode M, et al. Recurrent rearrangements of 11q14-22 in mucoepidermoid carcinoma. Cancer Genet Cytogenet. 1994;74:77-83.
4. El-Naggar AK, Lovell M, Killary A, et al. A mucoepidermoid carcinoma of the minor salivary gland with t(11;19) (q21;p13.1) as the sole karyotypic abnormality. Cancer Genet Cytogenet. 1996;87:29-33.
5. Jin Y, Mertens F, Limon J, et al. Characteristic karyotypic features in lachrymal and salivary gland carcinomas. Br J Cancer. 1994;70:42-47.
6. Jin C, Martins C, Jin Y, et al. Characterization of chromosome aberrations in salivary gland tumors by fluorescence in situ hybridization (FISH), including multicolor COBRA-FISH. Genes Chromosomes Cancer. 2001;30:161-167.
7. Johansson M, Mandahl N, Johansson L, et al. Translocation 11:19 in a mucoepidermoid tumor of the lung. Cancer Genet Cytogenet. 1995;80:85-86.
8. Behboudi A, Winnes M, Gorunova L, et al. Clear cell hidradenoma of the skin - a third tumor type with a t(11;19)-associated TORC1-MAML2 gene fusion. Genes Chromosomes Cancer. 2005;43:202-205.
9. Bullerdiek J, Haubrich J, Meyer K, et al. Translocation t(11;19) (q21;p13.1) as the sole chromosome abnormality in a cystadenolymphoma (Warthin's tumor) of the parotid gland. Cancer Genet Cytogenet. 1988;35:129-132.
10. Williamson JD, Simmons BH, El-Naggar AK, et al. Mucoepidermoid carcinoma involving Warthin tumor. Am J Clin Pathol. 2000;114:564-570.
11. Tonon G, Mody S, Wu L, et al. t(11;19) (q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway. Nat Genet. 2003;33:208-213.
12. Enlund F, Behboudi A, Andren Y, et al. Altered Notch signaling resulting from expression of a WANTP1-MAML2 gene fusion in mucoepidermoid carcinomas and benign Warthin's tumors. Exp Cell Res. 2004;292:21-28.
13. Conkright MD, Canettieri G, Screaton R, et al. TORCs transducers of regulated CREB activity. Mol Cell. 2003;12:413-423.
14. Stenman G. Fusion oncogenes and tumor-type specificity insights from salivary gland tumors. Semin Cancer Biol. 2005;15:224-235.
15. Martins C, Cavaco B, Tonon G, et al. A study of MECT1-MAML2 in mucoepidermoid carcinoma and Warthin's tumor of salivary glands. J Mol Diagn. 2004;6:205-210.