CD55 and CD59 Deficiency in Transplant Patient Populations: Possible Association With Paroxysmal Nocturnal Hemoglobinuria-Like Symptoms in Campath-Treated Patients

Transplantation Proceedings

Volumn 38, Issue 6, 2006, Pages 1750-1752

  Ruiz, P ^a   Weppler, D ^a   Tryphonopoulos, P ^a   Nishida, S ^a   Moon, J ^a   Kato, T ^a   Selvaggi, G ^a   Levi, D ^a   Madariaga, J ^a   DelaGarza, J ^a   Tuteja, S ^a   Garcia, M ^a   Tzakis, A ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALEMTUZUMAB; CD59 ANTIGEN; DECAY ACCELERATING FACTOR; GLYCOSYLPHOSPHATIDYLINOSITOL;

ARTICLE; CELL COUNT; DISEASE ASSOCIATION; GRANULOCYTE; HEMOLYSIS; HEMOLYTIC ANEMIA; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INTESTINE GRAFT; LIVER GRAFT; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; THROMBOSIS;

ANEMIA, HEMOLYTIC; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEOPLASM; ANTIGENS, CD; ANTIGENS, CD56; ANTIGENS, CD59; GENE DELETION; HEMOGLOBINURIA, PAROXYSMAL; HUMANS; IMMUNOSUPPRESSIVE AGENTS; THROMBOSIS;

EID: 33746873257     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2006.05.018     Document Type: Article

References (5)

1. Smith L.J. Paroxysmal nocturnal hemoglobinuria. Clin Lab Sci 17 (2004) 172
2. Fracchiolla N.S., Barcellini W., Bianchi P., et al. Biological and molecular characterization of PNH-like lymphocytes emerging after Campath-1H therapy. Br J Haematol 112 (2001) 969
3. Taylor V.C., Sims M., Brett S., et al. Antibody selection against CD52 produces a paroxysmal nocturnal haemoglobinuria phenotype in human lymphocytes by a novel mechanism. Biochem J 322 (1997) 919
4. Hillmen P., Bessler M., Mason P.J., et al. Specific defect in N-acetylglucosamine incorporation in the biosynthesis of the glycosylphosphatidylinositol anchor in cloned cell lines from patients with paroxysmal nocturnal hemoglobinuria. Proc Natl Acad Sci 90 (1993) 5272
5. Armstrong C., Schubert J., Ueda E., et al. Affected paroxysmal nocturnal hemoglobinuria T lymphocytes harbor a common defect in assembly of N-acetyl-D-glucosamine inositol phospholipid corresponding to that in class A Thy-1-murine lymphoma mutants. J Biol Chem 267 (1992) 25347