Development of lipase inhibitors from various derivatives of monascus pigment produced by Monascus fermentation

Food Chemistry

Volumn 101, Issue 1, 2007, Pages 357-364

  Kim, Jong Hoon ^a   Kim, Hyun Jung ^a   Kim, Chulyoung ^a   Jung, Heeyong ^a   Kim, Yong Ook ^a   Ju, Jae Yeong ^b   Shin, Chul Soo ^a  

^a Yonsei University   (South Korea)

^b CJ Corporation   (South Korea)

Author keywords

Fermentation; Lipase inhibitor; Monascus species; Pigment

Indexed keywords

AMINO ACID; DIPEPTIDE; ENZYME INHIBITOR; ESTER DERIVATIVE; INTESTINE ENZYME; MONASCUS PIGMENT; TRIACYLGLYCEROL LIPASE; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; ENZYME INHIBITION; FERMENTATION; IC 50; MONASCUS; NONHUMAN;

MONASCUS; SUIDAE;

EID: 33746871115     PISSN: 03088146     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodchem.2005.11.055     Document Type: Article

References (26)

1. Balsiger B.M., Murr M.M., Poggio J.L., and Sarr M.G. Bariatric surgery: surgery for weight control in patients with morbid obesity. Medical Clinics of North America 84 (2000) 477-489
2. Birch A.J., Cassera A., Fitton P., Holker J.S.E., Smith H., Thompson G.A., et al. Studies in relation to biosynthesis. Part XXX. Rotiorin, monascin, rubropunctatin. Journal of Chemical Society, C (1962) 3583-3586
3. Borgström B. Mode of action of tetrahydrolipstatin: a derivative of the naturally occurring lipase inhibitor lipstatin. Biochimica et Biophysica Acta 962 (1988) 308-316
4. Bray G.A. A concise review on the therapeutics of obesity. Nutrition 16 (2000) 953-960
5. Clapham J.C., Arch J.R.S., and Tadayyon M. Anti-obesity drugs: a critical review of current therapies and future opportunities. Pharmacology and Therapeutics 89 (2001) 81-121
6. Endo A. Monacolin K, a new hypocholesteolemic agent produced by a Monascus species. Journal of Antibiotics 32 (1979) 852-854
7. Fowell A.D.G., Robertson A., and Whelly W.B. Monascorubramin. Journal of Chemical Society (Special Publish) 5 (1956) 27-35
8. Hadfield J.R., Holker J.S.E., and Stanway D.N. The biosynthesis of fungal metabolites. Part II. The β-oxo-lactone equivalents in rubropunctatin and monascorubrin. Journal of Chemical Society 19 (1967) 751-755
9. Hadváry P., Sidler W., Meister W., Vetter W., and Wolfer H. The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipase. Journal of Biological chemistry 266 (1991) 2021-2027
10. Hiroi T., Shima T., Isobe A., and Kimura S. Studies on the structure of two pigment obtained from Monascus for sp. Journal of the Japanese Society of Food and Nutrition 28 (1975) 497-502
11. Hiroi T., Shima T., Suzuki T., Tsukioka M., and Ogasawara N. Hyperpigment-production mutant of Monascus anka for solid culture. Agricultural and Biological Chemistry 43 (1979) 1975-1976
12. Ju J.Y., Nam H.W., Yoon J.C., and Shin C.S. Extractive fermentation of red pigment using Monascus sp. J101. Korean Journal of Applied Microbiology and Biotechnology 22 (1994) 85-91
13. Jung H., Kim C., Kim K., and Shin C.S. Color characteristics of monascus pigments derived by fermentation with various amino acids. Journal of Agricultural and Food Chemistry 51 (2003) 1302-1306
14. Jůzlová P., Martínková L., and Křen V. Secondary metabolites of fungus Monascus: a review. Journal of Industrial Microbiology 16 (1996) 163-170
15. Kurono M., Nakanishi K., Shindo K., and Tada M. Biosynthesis of monascorubrin and monascoflavin. Chemical and Pharmaceutical Bulletin 11 (1963) 359-362
16. Lin T.F., Yakushijin K., Büchi G.H., and Demain A.L. Formation of water-soluble Monascus red pigments by biological and semi-synthetic process. Journal of Industrial Microbiology 9 (1992) 173-179
17. Lowry O.H., Rosebrough N., Farr A.L., and Rondall R.L. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 193 (1951) 265-273
18. Ma J., Li Y., Ye Q., Li J., Hua Y., Ju D., et al. Constituents of red yeast rice, a traditional Chinese food and medicine. Journal Agricultural of and Food Chemistry 48 (2000) 5220-5225
19. Manchand P.S., Whelly W.B., and Chen F.C. Isolation and structure of ankaflavin, a new pigment from Monascus anka. Phytochemistry 12 (1973) 2531-2532
20. Martínková L., Jůzlová P., and Veselý D. Biological activity of polyketide pigments produced by fungus Monascus. Journal of Applied Bacteriology 79 (1995) 609-616
21. Martínková L., Jůzlová P., Křent V., Kučerová Z., Havíček V., Olšovský P., et al. Biological activities of oligoketide pigments of Monascus purpureus. Food Additives and Contaminants 16 (1999) 15-24
22. Mayes P.A. Metabolism of lipids. In: Martin D.W., Mayes P.A., and Rodwell V.W. (Eds). Harper's review of biochemistry. 19th ed. Fatty acids (1983), Lange Medical Publications, Singapore 201-223
23. Moll, H. R., & Farr, D. R. (1976). Red pigment and process. US Patent 3, 993, 789.
24. Mukherjee M. Human digestive and metabolic lipases - a brief review. Journal of Molecular Catalysis B: Enzymatic 22 (2003) 369-376
25. Nicaud J.M., Madzak C., Broek P., Gysler C., Duboc P., Niederberger P., et al. Protein expression and secretion in the yeast Yarrowia lipolytica. FEMS Yeast Research 2 (2002) 371-379
26. Pittler M.H., and Ernst E. Dietary supplements for body-weight reduction: a systematic review. American Journal of Clinical Nutrition 79 (2004) 529-536