-
1
-
-
0031031440
-
Primary pulmonary hypertension
-
Rubin LJ. Primary pulmonary hypertension. N Engl J Med 1997;336:111-7.
-
(1997)
N Engl J Med
, vol.336
, pp. 111-117
-
-
Rubin, L.J.1
-
2
-
-
0021193273
-
Primary pulmonary hypertension: Natural history and the importance of thrombosis
-
Fuster V, Steele PM, Edwards WD, Gersh BJ, McGoon MD, Frye RL. Primary pulmonary hypertension: natural history and the importance of thrombosis. Circulation 1984;70:580-7.
-
(1984)
Circulation
, vol.70
, pp. 580-587
-
-
Fuster, V.1
Steele, P.M.2
Edwards, W.D.3
Gersh, B.J.4
McGoon, M.D.5
Frye, R.L.6
-
3
-
-
20344370254
-
Idiopathic pulmonary arterial hypertension in children
-
Rosenzweig EB, Barst RJ. Idiopathic pulmonary arterial hypertension in children. Curr Opin Pediatr 2005;17:372-80.
-
(2005)
Curr Opin Pediatr
, vol.17
, pp. 372-380
-
-
Rosenzweig, E.B.1
Barst, R.J.2
-
4
-
-
0037246057
-
Pulmonary arterial hypertension in children
-
Widlitz A, Barst RJ. Pulmonary arterial hypertension in children. Eur Respir J 2003;21:155-76.
-
(2003)
Eur Respir J
, vol.21
, pp. 155-176
-
-
Widlitz, A.1
Barst, R.J.2
-
5
-
-
4644295951
-
Primarypulmonary hypertension in children may have a different genetic background than in adults
-
Grunig E, Koehler R, Miltenberger-Miltenyi G, Zimmermann R, Gorenflo M, Mereles D et al. Primarypulmonary hypertension in children may have a different genetic background than in adults. Pediatr Res 2004;56:571-8.
-
(2004)
Pediatr Res
, vol.56
, pp. 571-578
-
-
Grunig, E.1
Koehler, R.2
Miltenberger-Miltenyi, G.3
Zimmermann, R.4
Gorenflo, M.5
Mereles, D.6
-
6
-
-
13444256185
-
Transforming growth factor-beta receptor mutations and pulmonary arterial hypertension in childhood
-
Harrison RE, Berger R, Haworth SG, Tulloh R, Mache CJ, Morrell NW et al. Transforming growth factor-beta receptor mutations and pulmonary arterial hypertension in childhood. Circulation 2005;111:435-41.
-
(2005)
Circulation
, vol.111
, pp. 435-441
-
-
Harrison, R.E.1
Berger, R.2
Haworth, S.G.3
Tulloh, R.4
Mache, C.J.5
Morrell, N.W.6
-
7
-
-
0014828621
-
The pathology of primary pulmonary hypertension
-
Wagenvoort CA. The pathology of primary pulmonary hypertension. J Pathol 1970; 101.
-
(1970)
J Pathol
, pp. 101
-
-
Wagenvoort, C.A.1
-
8
-
-
0022359912
-
Comparison of primary plexogenic arteriopathy in adults and children. A morphometric study in 40 patients
-
Yamaki S, Wagenvoort CA. Comparison of primary plexogenic arteriopathy in adults and children. A morphometric study in 40 patients. Br Heart J 1985;54:428-34.
-
(1985)
Br Heart J
, vol.54
, pp. 428-434
-
-
Yamaki, S.1
Wagenvoort, C.A.2
-
9
-
-
0033537630
-
Vasodilator therapy for primary pulmonary hypertension in children
-
Barst RJ, Maislin G, Fishman AP. Vasodilator therapy for primary pulmonary hypertension in children. Circulation 1999;99:1197-208.
-
(1999)
Circulation
, vol.99
, pp. 1197-1208
-
-
Barst, R.J.1
Maislin, G.2
Fishman, A.P.3
-
10
-
-
4043161231
-
Outcomes in children with idiopathic pulmonary arterial hypertension
-
Yung D, Widlitz AC, Rosenzweig EB, Kerstein D, Maislin G, Barst RJ. Outcomes in children with idiopathic pulmonary arterial hypertension. Circulation 2004;110:660-5.
-
(2004)
Circulation
, vol.110
, pp. 660-665
-
-
Yung, D.1
Widlitz, A.C.2
Rosenzweig, E.B.3
Kerstein, D.4
Maislin, G.5
Barst, R.J.6
-
11
-
-
0025837793
-
Survival in patients with primary pulmonary hypertension: Results from a national prospective registry
-
D'Alonzo GE, Barst RJ, Ayres SM, Bergofsky EH, Brundage BH, Detre KM et al. Survival in patients with primary pulmonary hypertension: Results from a national prospective registry. Ann Intern Med 1991;115:343-9.
-
(1991)
Ann Intern Med
, vol.115
, pp. 343-349
-
-
D'Alonzo, G.E.1
Barst, R.J.2
Ayres, S.M.3
Bergofsky, E.H.4
Brundage, B.H.5
Detre, K.M.6
-
12
-
-
3142777629
-
Prognosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines
-
McLaughlin VV, Presberg KW, Doyle RL, Abman SH, McCrory DC, Fortin T et al. Prognosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest 2004;126:78S-92S.
-
(2004)
Chest
, vol.126
-
-
McLaughlin, V.V.1
Presberg, K.W.2
Doyle, R.L.3
Abman, S.H.4
McCrory, D.C.5
Fortin, T.6
-
14
-
-
20344374050
-
Effects of long-term bosentan in children with pulmonary arterial hypertension
-
Rosenzweig EB, Ivy DD, Widlitz A, Doran A, Claussen LR, Yung D et al. Effects of long-term bosentan in children with pulmonary arterial hypertension. J Am Coll Cardiol 2005;46:697-704.
-
(2005)
J Am Coll Cardiol
, vol.46
, pp. 697-704
-
-
Rosenzweig, E.B.1
Ivy, D.D.2
Widlitz, A.3
Doran, A.4
Claussen, L.R.5
Yung, D.6
-
15
-
-
0030813510
-
The effect of anticoagulant therapy in primary and anorectic drug-induced pulmonary hypertension
-
Frank H, Mlczoch J, Huber K, Schuster E, Gurtner HP, Kneussl M. The effect of anticoagulant therapy in primary and anorectic drug-induced pulmonary hypertension. Chest 1997;112:714-21.
-
(1997)
Chest
, vol.112
, pp. 714-721
-
-
Frank, H.1
Mlczoch, J.2
Huber, K.3
Schuster, E.4
Gurtner, H.P.5
Kneussl, M.6
-
16
-
-
0027324745
-
Expression of endothelin-1 in the lungs of patients with pulmonary hypertension
-
Giaid A, Yanagisawa M, Langleben D, Michel RP, Levy R, Shennib H et al. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med 1993;328:1732-9.
-
(1993)
N Engl J Med
, vol.328
, pp. 1732-1739
-
-
Giaid, A.1
Yanagisawa, M.2
Langleben, D.3
Michel, R.P.4
Levy, R.5
Shennib, H.6
-
17
-
-
20244386797
-
Effects of the thromboxane synthetase inhibitor and receptor antagonist terbogrel in patients with primary pulmonary hypertension
-
Langleben D, Christman BW, Barst RJ, Dias VC, Galie N, Higenbottam TW et al. Effects of the thromboxane synthetase inhibitor and receptor antagonist terbogrel in patients with primary pulmonary hypertension. Am Heart J 2002;143:E4.
-
(2002)
Am Heart J
, vol.143
-
-
Langleben, D.1
Christman, B.W.2
Barst, R.J.3
Dias, V.C.4
Galie, N.5
Higenbottam, T.W.6
-
18
-
-
0031869664
-
Inhaled nitric oxide as a screening agent for safely identifying responders to oral calcium-channel blockers in primary pulmonary hypertension
-
Sitbon O, Humbert M, Jagot JL, Taravella O, Fartoukh M, Parent F et al. Inhaled nitric oxide as a screening agent for safely identifying responders to oral calcium-channel blockers in primary pulmonary hypertension. Eur Respir J 1998;12:265-70.
-
(1998)
Eur Respir J
, vol.12
, pp. 265-270
-
-
Sitbon, O.1
Humbert, M.2
Jagot, J.L.3
Taravella, O.4
Fartoukh, M.5
Parent, F.6
-
19
-
-
0022635636
-
Pharmacologically induced pulmonary vasodilatation in children and young adults with primary pulmonary hypertension
-
Barst RJ. Pharmacologically induced pulmonary vasodilatation in children and young adults with primary pulmonary hypertension. Chest 1986;89:497-503.
-
(1986)
Chest
, vol.89
, pp. 497-503
-
-
Barst, R.J.1
-
20
-
-
0026632785
-
The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension
-
Rich S, Kaufmann E, Levy PS. The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. N Engl J Med 1992;327:76-81.
-
(1992)
N Engl J Med
, vol.327
, pp. 76-81
-
-
Rich, S.1
Kaufmann, E.2
Levy, P.S.3
-
21
-
-
0032576672
-
Reduction in pulmonary vascular resistance with long-term epoprostenol (prostacyclin) therapy in primary pulmonary hypertension
-
McLaughlin VV. Genthner DE, Panella MM, Rich S. Reduction in pulmonary vascular resistance with long-term epoprostenol (prostacyclin) therapy in primary pulmonary hypertension. N Engl J Med 1998;338:273-7.
-
(1998)
N Engl J Med
, vol.338
, pp. 273-277
-
-
McLaughlin, V.V.1
Genthner, D.E.2
Panella, M.M.3
Rich, S.4
-
22
-
-
0028597038
-
Survival in primary pulmonary hypertension with long-term continuous intravenous prostacyclin
-
Barst RJ, Rubin LJ, McGoon MD, Caldwell EJ, Long WA, Levy PS. Survival in primary pulmonary hypertension with long-term continuous intravenous prostacyclin. Ann Intern Med 1994;121:409-15.
-
(1994)
Ann Intern Med
, vol.121
, pp. 409-415
-
-
Barst, R.J.1
Rubin, L.J.2
McGoon, M.D.3
Caldwell, E.J.4
Long, W.A.5
Levy, P.S.6
-
23
-
-
17144452827
-
Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized controlled trial
-
Badesch DB, Tapson VF, McGoon MD, Brundage BH, Rubin LJ, Wigley FM et al. Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized controlled trial. Ann Intern Med 2000;132:425-34.
-
(2000)
Ann Intern Med
, vol.132
, pp. 425-434
-
-
Badesch, D.B.1
Tapson, V.F.2
McGoon, M.D.3
Brundage, B.H.4
Rubin, L.J.5
Wigley, F.M.6
-
24
-
-
0030031888
-
A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension
-
The Primary Pulmonary Hypertension Study Group
-
Barst RJ, Rubin LJ, Long WA, McGoon MD, Rich S, Badesch DB et al. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group. N Engl J Med 1996;334:296-302.
-
(1996)
N Engl J Med
, vol.334
, pp. 296-302
-
-
Barst, R.J.1
Rubin, L.J.2
Long, W.A.3
McGoon, M.D.4
Rich, S.5
Badesch, D.B.6
-
25
-
-
0033954110
-
Epoprostenol for treatment of pulmonary hypertension in patients with systemic lupus erythematosus
-
Robbins IM, Gaine SP, Schilz R, Tapson VF, Rubin LJ, Loyd JE. Epoprostenol for treatment of pulmonary hypertension in patients with systemic lupus erythematosus. Chest 2000;117:14-8.
-
(2000)
Chest
, vol.117
, pp. 14-18
-
-
Robbins, I.M.1
Gaine, S.P.2
Schilz, R.3
Tapson, V.F.4
Rubin, L.J.5
Loyd, J.E.6
-
26
-
-
0037126044
-
Survival in primary pulmonary hypertension: The impact of epoprostenol therapy
-
McLaughlin VV, Shillington A, Rich S. Survival in primary pulmonary hypertension: the impact of epoprostenol therapy. Circulation 2002;106:1477-82.
-
(2002)
Circulation
, vol.106
, pp. 1477-1482
-
-
McLaughlin, V.V.1
Shillington, A.2
Rich, S.3
-
27
-
-
0033790605
-
Epoprostenol for treatment of pulmonary hypertension in patients with systemic lupus erythematosus
-
Horn EM, Barst RJ, Poon M. Epoprostenol for treatment of pulmonary hypertension in patients with systemic lupus erythematosus. Chest 2000;118:1229-30.
-
(2000)
Chest
, vol.118
, pp. 1229-1230
-
-
Horn, E.M.1
Barst, R.J.2
Poon, M.3
-
28
-
-
0034696528
-
Epoprostenol (prostacyclin) and pulmonary hypertension
-
Fishman AP. Epoprostenol (prostacyclin) and pulmonary hypertension. Ann Intern Med 2000;132:500-2.
-
(2000)
Ann Intern Med
, vol.132
, pp. 500-502
-
-
Fishman, A.P.1
-
29
-
-
0041353958
-
Prostanoids for pulmonary arterial hypertension
-
Galie N, Manes A, Branzi A. Prostanoids for pulmonary arterial hypertension. Am J Respir Med 2003;2:123-37.
-
(2003)
Am J Respir Med
, vol.2
, pp. 123-137
-
-
Galie, N.1
Manes, A.2
Branzi, A.3
-
30
-
-
1842476943
-
Weaning and discontinuation of epoprostenol in children with idiopathic pulmonary arterial hypertension receiving concomitant bosentan
-
Ivy DD, Doran A, Claussen L, Bingaman D, Yetman A. Weaning and discontinuation of epoprostenol in children with idiopathic pulmonary arterial hypertension receiving concomitant bosentan. Am J Cardiol 2004;93:943-6.
-
(2004)
Am J Cardiol
, vol.93
, pp. 943-946
-
-
Ivy, D.D.1
Doran, A.2
Claussen, L.3
Bingaman, D.4
Yetman, A.5
-
31
-
-
0037086133
-
Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: A double-blind, randomized, placebo-controlled trial
-
Simonneau G, Barst RJ, Galie N, Naeije R, Rich S, Bourge RC et al. Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled trial. Am J Respir Crit Care Med 2002;165:800-4.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 800-804
-
-
Simonneau, G.1
Barst, R.J.2
Galie, N.3
Naeije, R.4
Rich, S.5
Bourge, R.C.6
-
32
-
-
0038037766
-
Beraprost therapy for pulmonary arterial hypertension
-
Barst RJ, McGoon M, McLaughlin V, Tapson V, Rich S, Rubin L et al. Beraprost therapy for pulmonary arterial hypertension. J Am Coll Cardiol 2003;41:2119-25.
-
(2003)
J Am Coll Cardiol
, vol.41
, pp. 2119-2125
-
-
Barst, R.J.1
McGoon, M.2
McLaughlin, V.3
Tapson, V.4
Rich, S.5
Rubin, L.6
-
33
-
-
0026681422
-
Iloprost. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in peripheral vascular disease, myocardial ischaemia and extra-corporeal circulation procedures
-
Grant SM, Goa KL. Iloprost. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in peripheral vascular disease, myocardial ischaemia and extra-corporeal circulation procedures. Drugs 1992;43:889-924.
-
(1992)
Drugs
, vol.43
, pp. 889-924
-
-
Grant, S.M.1
Goa, K.L.2
-
34
-
-
0036682273
-
Inhaled iloprost for severe pulmonary hypertension
-
Olschewski H, Simonneau G, Galie N, Higenbottam T, Naeije R, Rubin LJ et al. Inhaled iloprost for severe pulmonary hypertension. N Engl J Med 2002;347:322-9.
-
(2002)
N Engl J Med
, vol.347
, pp. 322-329
-
-
Olschewski, H.1
Simonneau, G.2
Galie, N.3
Higenbottam, T.4
Naeije, R.5
Rubin, L.J.6
-
35
-
-
0034702248
-
Long-term treatment of primary pulmonary hypertension with aerosolized iloprost, a prostacyclin analogue
-
Hoeper MM, Schwarze M, Ehlerding S, Adler-Schuermeyer A, Spiekerkoetter E, Niedermeyer J et al. Long-term treatment of primary pulmonary hypertension with aerosolized iloprost, a prostacyclin analogue. N Engl J Med 2000;342:1866-70.
-
(2000)
N Engl J Med
, vol.342
, pp. 1866-1870
-
-
Hoeper, M.M.1
Schwarze, M.2
Ehlerding, S.3
Adler-Schuermeyer, A.4
Spiekerkoetter, E.5
Niedermeyer, J.6
-
36
-
-
0142074258
-
Pharmacodynamics and pharmacokinetics of inhaled iloprost, aerosolized by three different devices, in severe pulmonary hypertension
-
Olschewski H, Rohde B, Behr J, Ewert R, Gessler T, Ghofrani HA et al. Pharmacodynamics and pharmacokinetics of inhaled iloprost, aerosolized by three different devices, in severe pulmonary hypertension. Chest 2003;124:1294-304.
-
(2003)
Chest
, vol.124
, pp. 1294-1304
-
-
Olschewski, H.1
Rohde, B.2
Behr, J.3
Ewert, R.4
Gessler, T.5
Ghofrani, H.A.6
-
37
-
-
0035462104
-
Long-term inhalation of iloprost in a child with primary pulmonary hypertension: An alternative to continuous infusion
-
Beghetti M, Berner M, Rimensberger PC. Long-term inhalation of iloprost in a child with primary pulmonary hypertension: an alternative to continuous infusion. Heart 2001;86:E10.
-
(2001)
Heart
, vol.86
-
-
Beghetti, M.1
Berner, M.2
Rimensberger, P.C.3
-
38
-
-
4444330401
-
Aerosolized iloprost as a bridge to lung transplantation in a patient with cystic fibrosis and pulmonary hypertension
-
Tissieres P, Nicod L, Barazzone-Argiroffo C, Rimensberger PC, Beghetti M. Aerosolized iloprost as a bridge to lung transplantation in a patient with cystic fibrosis and pulmonary hypertension. Ann Thorac Surg 2004;78:e48-50.
-
(2004)
Ann Thorac Surg
, vol.78
-
-
Tissieres, P.1
Nicod, L.2
Barazzone-Argiroffo, C.3
Rimensberger, P.C.4
Beghetti, M.5
-
39
-
-
0029831414
-
NO hyperpolarizes pulmonary artery smooth muscle cells and decreases the intracellular Ca2+ concentration by activating voltage-gated K+ channels
-
Yuan XJ, Tod ML, Rubin LJ, Blaustein MP. NO hyperpolarizes pulmonary artery smooth muscle cells and decreases the intracellular Ca2+ concentration by activating voltage-gated K+ channels. Proc Natl Acad Sci U S A 1996;93:10489-94.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 10489-10494
-
-
Yuan, X.J.1
Tod, M.L.2
Rubin, L.J.3
Blaustein, M.P.4
-
40
-
-
0026002659
-
Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension
-
Pepke-Zaba J, Higenbottam TW, Dinh-Xuan AT, Stone D, Wallwork J. Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension. Lancet 1991;338:1173-4.
-
(1991)
Lancet
, vol.338
, pp. 1173-1174
-
-
Pepke-Zaba, J.1
Higenbottam, T.W.2
Dinh-Xuan, A.T.3
Stone, D.4
Wallwork, J.5
-
41
-
-
0029449414
-
Clinical applications of inhaled nitric oxide in children with pulmonary hypertension
-
Wessel DL, Adatia I. Clinical applications of inhaled nitric oxide in children with pulmonary hypertension. Adv Pharmacol 1995;34:475-504.
-
(1995)
Adv Pharmacol
, vol.34
, pp. 475-504
-
-
Wessel, D.L.1
Adatia, I.2
-
42
-
-
0029980295
-
Inhaled nitric oxide to test the vasodilator capacity of the pulmonary vascular bed in children with long-standing pulmonary hypertension and congenital heart disease
-
Berner M, Beghetti M, Spahr-Schopfer I, Oberhansli I, Friedli B. Inhaled nitric oxide to test the vasodilator capacity of the pulmonary vascular bed in children with long-standing pulmonary hypertension and congenital heart disease. Am J Cardiol 1996;77:532-5.
-
(1996)
Am J Cardiol
, vol.77
, pp. 532-535
-
-
Berner, M.1
Beghetti, M.2
Spahr-Schopfer, I.3
Oberhansli, I.4
Friedli, B.5
-
43
-
-
0029896789
-
Pulsed delivery of inhaled nitric oxide to patients with primary pulmonary hypertension: An ambulatory delivery system and initial clinical tests
-
Channick RN, Newhart JW, Johnson FW, Williams PJ, Auger WR, Fedullo PF et al. Pulsed delivery of inhaled nitric oxide to patients with primary pulmonary hypertension: an ambulatory delivery system and initial clinical tests. Chest 1996;109:1545-9.
-
(1996)
Chest
, vol.109
, pp. 1545-1549
-
-
Channick, R.N.1
Newhart, J.W.2
Johnson, F.W.3
Williams, P.J.4
Auger, W.R.5
Fedullo, P.F.6
-
44
-
-
0037106989
-
Effect of sildenafil on the acute pulmonary vasodilator response to inhaled nitric oxide in adults with primary pulmonary hypertension
-
Lepore JJ, Maroo A, Pereira NL, Ginns LC, Dec GW, Zapol WM et al. Effect of sildenafil on the acute pulmonary vasodilator response to inhaled nitric oxide in adults with primary pulmonary hypertension. Am J Cardiol 2002;90:677-80.
-
(2002)
Am J Cardiol
, vol.90
, pp. 677-680
-
-
Lepore, J.J.1
Maroo, A.2
Pereira, N.L.3
Ginns, L.C.4
Dec, G.W.5
Zapol, W.M.6
-
45
-
-
0027935877
-
Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase
-
Archer SL, Huang JM, Hampl V, Nelson DP, Shultz PJ, Weir EK. Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A 1994;91:7583-7.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 7583-7587
-
-
Archer, S.L.1
Huang, J.M.2
Hampl, V.3
Nelson, D.P.4
Shultz, P.J.5
Weir, E.K.6
-
46
-
-
0026327575
-
Ca/CaM-stimulated and cGMP-specific phosphodiesterases in vascular and non-vascular tissues
-
Ahn HS, Foster M, Cable M, Pitts BJ, Sybertz EJ. Ca/CaM-stimulated and cGMP-specific phosphodiesterases in vascular and non-vascular tissues. Adv Exp Med Biol 1991;308:191-7.
-
(1991)
Adv Exp Med Biol
, vol.308
, pp. 191-197
-
-
Ahn, H.S.1
Foster, M.2
Cable, M.3
Pitts, B.J.4
Sybertz, E.J.5
-
47
-
-
1842530387
-
Clinical efficacy of sildenafil in primary pulmonary hypertension: A randomized, placebo-controlled, double-blind, crossover study
-
Sastry BK, Narasimhan C, Reddy NK, Raju BS. Clinical efficacy of sildenafil in primary pulmonary hypertension: a randomized, placebo-controlled, double-blind, crossover study. J Am Coll Cardiol 2004;43:1149-53.
-
(2004)
J Am Coll Cardiol
, vol.43
, pp. 1149-1153
-
-
Sastry, B.K.1
Narasimhan, C.2
Reddy, N.K.3
Raju, B.S.4
-
48
-
-
0036663343
-
A study of clinical efficacy of sildenafil in patients with primary pulmonary hypertension
-
Sastry BK, Narasimhan C, Reddy NK, Anand B, Prakash GS, Raju PR et al. A study of clinical efficacy of sildenafil in patients with primary pulmonary hypertension. Indian Heart J 2002;54:410-4.
-
(2002)
Indian Heart J
, vol.54
, pp. 410-414
-
-
Sastry, B.K.1
Narasimhan, C.2
Reddy, N.K.3
Anand, B.4
Prakash, G.S.5
Raju, P.R.6
-
49
-
-
21044449937
-
Beneficial effect of oral sildenafil therapy on childhood pulmonary arterial hypertension: Twelve-month clinical trial of a single-drug, open-label, pilot study
-
Humpl T, Reyes JT, Holtby H, Stephens D, Adatia I. Beneficial effect of oral sildenafil therapy on childhood pulmonary arterial hypertension: twelve-month clinical trial of a single-drug, open-label, pilot study. Circulation 2005;111:3274-80.
-
(2005)
Circulation
, vol.111
, pp. 3274-3280
-
-
Humpl, T.1
Reyes, J.T.2
Holtby, H.3
Stephens, D.4
Adatia, I.5
-
50
-
-
0037006966
-
Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension
-
Ghofrani HA, Wiedemann R, Rose F, Olschewski H, Schermuly RT, Weissmann N et al. Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension. Ann Intern Med 2002;136:515-22.
-
(2002)
Ann Intern Med
, vol.136
, pp. 515-522
-
-
Ghofrani, H.A.1
Wiedemann, R.2
Rose, F.3
Olschewski, H.4
Schermuly, R.T.5
Weissmann, N.6
-
51
-
-
0037868048
-
Oral sildenafil as long-term adjunct therapy to inhaled iloprost in severe pulmonary arterial hypertension
-
Ghofrani HA, Rose F, Schermuly RT, Olschewski H, Wiedemann R, Kreckel A et al. Oral sildenafil as long-term adjunct therapy to inhaled iloprost in severe pulmonary arterial hypertension. J Am Coll Cardiol 2003;42:158-64.
-
(2003)
J Am Coll Cardiol
, vol.42
, pp. 158-164
-
-
Ghofrani, H.A.1
Rose, F.2
Schermuly, R.T.3
Olschewski, H.4
Wiedemann, R.5
Kreckel, A.6
-
52
-
-
0023859136
-
A novel potent vasoconstrictor peptide produced by vascular endothelial cells
-
Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988;332:411-5.
-
(1988)
Nature
, vol.332
, pp. 411-415
-
-
Yanagisawa, M.1
Kurihara, H.2
Kimura, S.3
Tomobe, Y.4
Kobayashi, M.5
Mitsui, Y.6
-
53
-
-
0034727717
-
Primary pulmonary hypertension: A vascular biology and translational research 'Work in progress'
-
Archer S, Rich S. Primary pulmonary hypertension: a vascular biology and translational research 'Work in progress'. Circulation 2000;102:2781-91.
-
(2000)
Circulation
, vol.102
, pp. 2781-2791
-
-
Archer, S.1
Rich, S.2
-
54
-
-
0027410863
-
Endothelin-1 in primary pulmonary hypertension and the Eisenmenger syndrome
-
Cacoub P, Dorent R, Maistre G, Nataf P, Carayon A, Piette C et al. Endothelin-1 in primary pulmonary hypertension and the Eisenmenger syndrome. Am J Cardiol 1993;71:448-50.
-
(1993)
Am J Cardiol
, vol.71
, pp. 448-450
-
-
Cacoub, P.1
Dorent, R.2
Maistre, G.3
Nataf, P.4
Carayon, A.5
Piette, C.6
-
56
-
-
0028946351
-
Endothelin-1 in idiopathic pulmonary fibrosis
-
Uguccioni M, Pulsatelli L, Grigolo B, Facchini A, Fasano L, Cinti C et al. Endothelin-1 in idiopathic pulmonary fibrosis. J Clin Pathol 1995;48:330-4.
-
(1995)
J Clin Pathol
, vol.48
, pp. 330-334
-
-
Uguccioni, M.1
Pulsatelli, L.2
Grigolo, B.3
Facchini, A.4
Fasano, L.5
Cinti, C.6
-
57
-
-
0026034713
-
Increased plasma endothelin-1 in pulmonary hypertension: Marker or mediator of disease?
-
Stewart DJ, Levy RD, Cernacek P, Langleben D. Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease? Ann Intern Med 1991;114:464-9.
-
(1991)
Ann Intern Med
, vol.114
, pp. 464-469
-
-
Stewart, D.J.1
Levy, R.D.2
Cernacek, P.3
Langleben, D.4
-
58
-
-
0028788150
-
Neurohormonal activation in patients with right ventricular failure from pulmonary hypertension: Relation to hemodynamic variables and endothelin levels
-
Nootens M, Kaufmann E, Rector T, Toher C, Judd D, Francis GS et al. Neurohormonal activation in patients with right ventricular failure from pulmonary hypertension: relation to hemodynamic variables and endothelin levels. J Am Coll Cardiol 1995;26:1581-5.
-
(1995)
J Am Coll Cardiol
, vol.26
, pp. 1581-1585
-
-
Nootens, M.1
Kaufmann, E.2
Rector, T.3
Toher, C.4
Judd, D.5
Francis, G.S.6
-
59
-
-
0037022927
-
Selective upregulation of endothelin B receptor gene expression in severe pulmonary hypertension
-
Bauer M, Wilkens H, Langer F, Schneider SO, Lausberg H, Schafers HJ. Selective upregulation of endothelin B receptor gene expression in severe pulmonary hypertension. Circulation 2002;105:1034-6.
-
(2002)
Circulation
, vol.105
, pp. 1034-1036
-
-
Bauer, M.1
Wilkens, H.2
Langer, F.3
Schneider, S.O.4
Lausberg, H.5
Schafers, H.J.6
-
60
-
-
0037149718
-
Bosentan therapy for pulmonary arterial hypertension
-
Rubin LJ, Badesch DB, Barst RJ, Galie N, Black CM, Keogh A et al. Bosentan therapy for pulmonary arterial hypertension. N Engl J Med 2002;346:896-903.
-
(2002)
N Engl J Med
, vol.346
, pp. 896-903
-
-
Rubin, L.J.1
Badesch, D.B.2
Barst, R.J.3
Galie, N.4
Black, C.M.5
Keogh, A.6
-
61
-
-
0035818316
-
Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: A randomised placebo-controlled study
-
Channick RN, Simonneau G, Sitbon O, Robbins IM, Frost A, Tapson VF et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Lancet 2001;358:1119-23.
-
(2001)
Lancet
, vol.358
, pp. 1119-1123
-
-
Channick, R.N.1
Simonneau, G.2
Sitbon, O.3
Robbins, I.M.4
Frost, A.5
Tapson, V.F.6
-
62
-
-
0344406959
-
Pharmacokinetics, safety, and efficacy of bosentan in pediatric patients with pulmonary arterial hypertension
-
Barst RJ, Ivy D, Dingemanse J, Widlitz A, Schmitt K, Doran A et al. Pharmacokinetics, safety, and efficacy of bosentan in pediatric patients with pulmonary arterial hypertension. Clin Pharmacol Ther 2003;73:372-82.
-
(2003)
Clin Pharmacol Ther
, vol.73
, pp. 372-382
-
-
Barst, R.J.1
Ivy, D.2
Dingemanse, J.3
Widlitz, A.4
Schmitt, K.5
Doran, A.6
-
63
-
-
33744934345
-
Response to bosentan in children with pulmonary hypertension
-
doi: 10.1136
-
Maiya S, Hislop AA, Flynn Y, Haworth SG. Response to bosentan in children with pulmonary hypertension. Heart 2005 (doi: 10.1136).
-
(2005)
Heart
-
-
Maiya, S.1
Hislop, A.A.2
Flynn, Y.3
Haworth, S.G.4
-
64
-
-
33746824393
-
Clinical experience with bosentan in children with pulmonary arterial hypertension
-
abstract 171
-
Beghetti M, Ivy D, Barst R. Clinical experience with bosentan in children with pulmonary arterial hypertension [abstract 171]. Eur J Clin Invest 2005;35 (Suppl. 2):58.
-
(2005)
Eur J Clin Invest
, vol.35
, Issue.2 SUPPL.
, pp. 58
-
-
Beghetti, M.1
Ivy, D.2
Barst, R.3
-
65
-
-
0037151645
-
Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: Prognostic factors and survival
-
Sitbon O, Humbert M, Nunes H, Parent F, Garcia G, Herve P et al. Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival. J Am Coll Cardiol 2002;40:780-8.
-
(2002)
J Am Coll Cardiol
, vol.40
, pp. 780-788
-
-
Sitbon, O.1
Humbert, M.2
Nunes, H.3
Parent, F.4
Garcia, G.5
Herve, P.6
-
66
-
-
24644489695
-
R) as treatment for pulmonary arterial hypertension (PAH) due to congenital heart disease in infants and young children
-
R) as treatment for pulmonary arterial hypertension (PAH) due to congenital heart disease in infants and young children. Z Kardiol 2005;94:570-4.
-
(2005)
Z Kardiol
, vol.94
, pp. 570-574
-
-
Gilbert, N.1
Luther, Y.C.2
Miera, O.3
Nagdyman, N.4
Ewert, P.5
Berger, F.6
-
67
-
-
28444483305
-
Long-term safety profile of bosentan in daily practice
-
abstract 173
-
Humbert M, Kiely DG, Carlsen J, Hoeper MM. Long-term safety profile of bosentan in daily practice [abstract 173]. Eur J Clin Invest 2005;35 (Suppl. 2):58.
-
(2005)
Eur J Clin Invest
, vol.35
, Issue.2 SUPPL.
, pp. 58
-
-
Humbert, M.1
Kiely, D.G.2
Carlsen, J.3
Hoeper, M.M.4
-
68
-
-
33746817680
-
Safety experience with bosentan in children under 12 years with pulmonary arterial hypertension: TRAX database
-
abstract 182
-
Beghetti M, Humbert M, Hoerper M. Safety experience with bosentan in children under 12 years with pulmonary arterial hypertension: TRAX database [abstract 182]. Eur J Clin Invest 2005;35 (Suppl. 2):61.
-
(2005)
Eur J Clin Invest
, vol.35
, Issue.2 SUPPL.
, pp. 61
-
-
Beghetti, M.1
Humbert, M.2
Hoerper, M.3
-
69
-
-
10744230817
-
Sitaxsentan therapy for pulmonary arterial hypertension
-
Barst RJ, Langleben D, Frost A, Horn EM, Oudiz R, Shapiro S et al. Sitaxsentan therapy for pulmonary arterial hypertension. Am J Respir Crit Care Med 2004;169:441-7.
-
(2004)
Am J Respir Crit Care Med
, vol.169
, pp. 441-447
-
-
Barst, R.J.1
Langleben, D.2
Frost, A.3
Horn, E.M.4
Oudiz, R.5
Shapiro, S.6
-
70
-
-
33746821652
-
STRIDE-2 Trial: A placebo-controlled study for sitaxsentan in pulmonary arterial hypertension
-
abstract 26
-
Galie N, Langleben D, Badesch D, Frost A, Lawrence EC, Naeije R et al. STRIDE-2 Trial: a placebo-controlled study for sitaxsentan in pulmonary arterial hypertension. Eur Heart J 2005;26 [abstract 26].
-
(2005)
Eur Heart J
, vol.26
-
-
Galie, N.1
Langleben, D.2
Badesch, D.3
Frost, A.4
Lawrence, E.C.5
Naeije, R.6
-
71
-
-
22844436819
-
Ambrisentan therapy for pulmonary arterial hypertension
-
Galie N, Badesch D, Oudiz R, Simonneau G, McGoon MD, Keogh AM et al. Ambrisentan therapy for pulmonary arterial hypertension. J Am Coll Cardiol 2005;46:529-35.
-
(2005)
J Am Coll Cardiol
, vol.46
, pp. 529-535
-
-
Galie, N.1
Badesch, D.2
Oudiz, R.3
Simonneau, G.4
McGoon, M.D.5
Keogh, A.M.6
-
72
-
-
33646243000
-
Response to bosentan in children with pulmonary hypertension
-
Maiya S, Hislop AA, Flynn Y, Haworth SG. Response to bosentan in children with pulmonary hypertension. Heart 2006;92:664-70.
-
(2006)
Heart
, vol.92
, pp. 664-670
-
-
Maiya, S.1
Hislop, A.A.2
Flynn, Y.3
Haworth, S.G.4
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