Visual restoration in cortical blindness: Insights from natural and TMS-induced blindsight

Neuropsychological Rehabilitation

Volumn 16, Issue 4, 2006, Pages 377-396

  Ro, Tony ^a,b   Rafal, Robert ^c  

^a RICE UNIVERSITY   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c BANGOR UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DAMAGE; CEREBRAL BLINDNESS; COLOR VISION; EYE FIXATION; HEAD MOVEMENT; HEMIANOPIA; HOMONYMOUS HEMIANOPIA; HUMAN; OCCIPITAL CORTEX; RETINOTECTAL PROJECTION; REVIEW; SACCADIC EYE MOVEMENT; SCOTOMA; SUPERIOR COLLICULUS; TRANSCRANIAL MAGNETIC STIMULATION; TRAUMATIC BRAIN INJURY; VISION; VISUAL CORTEX; VISUAL DISCRIMINATION; VISUAL FIELD DEFECT; VISUAL STIMULATION;

ANIMALS; AWARENESS; BLINDNESS, CORTICAL; FUNCTIONAL LATERALITY; HEMIANOPSIA; HUMANS; RECOVERY OF FUNCTION; TRANSCRANIAL MAGNETIC STIMULATION; VISION; VISUAL CORTEX; VISUAL PATHWAYS;

EID: 33746833650     PISSN: 09602011     EISSN: 14640694     Source Type: Journal    
DOI: 10.1080/09602010500435989     Document Type: Review

References (86)

1. Balliet, R., Blood, K. M., & Bach-y-Rita, P. (1985). Visual field rehabilitation in the cortically blind? Journal of Neurology, Neurosurgy, and Psychiatry, 48, 1113-1124.
2. Barbur, J. L., Watson, J. D., Frackowiak, R. S., & Zeki, S. (1993). Conscious visual perception without V1. Brain, 116(Pt 6), 1293-1302.
3. Baylis, G., Driver, J., & Rafal, R. (1993). Extinction and stimulus repetition. Journal of Cognitive Neuroscience, 5, 453-466.
4. Behrmann, M., & Moscovitch, M. (1994). Object-centered neglect in patients with unilateral neglect: Effects of left-right coordinates of objects. Journal of Cognitive Neuroscience, 6, 1-16.
5. Behrmann, M., & Tipper, S. P. (1994). Object-based visual attention: Evidence from unilateral neglect. In M. Moscovitch (Ed.), Attention and performance. XIV: Conscious and nonconscious processing and cognitive functioning (pp. 351-376). Hillsdale, NJ: Lawrence Erlbaum.
6. Berti, A., & Rizzolatti, G. (1992). Visual processing without awareness: Evidence from unilateral neglect. Journal of Cognitive Neuroscience, 4, 345-351.
7. Blythe, I. M., Kennard, C., & Ruddock, K. H. (1987). Residual vision in patients with retrogeniculate lesions of the visual pathways. Brain, 110(Pt 4), 887-905.
8. Boyer, J., Harrison, S., & Ro, T. (2005). Unconscious processing of orientation and color without primary visual cortex. Proceedings of the National Academy of Sciences, 102, 16875-16879.
9. Cowey, A. (1967). Perimetric study of field defects in monkeys after cortical and retinal ablations. Quarterly Journal of Experimental Psychology, 19, 232-245.
10. Cowey, A. (2004). The 30th Sir Frederick Bartlett lecture. Fact, artefact, and myth about blindsight. Quarterly Journal of Experimental Psychology, 57A, 577-609.
11. Danziger, S., Fendrich, R., & Rafal, R. D. (1997). Inhibitory tagging of locations in the blind field of hemianopic patients. Consciousness and Cognition, 6, 291-307.
12. Danziger, S., Kingstone, A., & Rafal, R. (1998). Reflexive orienting to signals in the neglected visual field. Psychological Science, 9, 119-123.
13. Dehaene, S., & Naccache, L. (2001). Towards a cognitive neuroscience of consciousness: Basic evidence and a workspace framework. Cognition, 79, 1-37.
14. Dennett, D. (2001). Are we explaining consciousness yet? Cognition, 79, 221-237.
15. Desimone, R., Schein, S. J., Moran, J., & Ungerleider, L. G. (1985). Contour, color and shape analysis beyond the striate cortex. Vision Research, 25, 441-452.
16. Dodds, C., Machado, L., Rafal, R., & Ro, T. (2002). A temporal/nasal asymmetry for blindsight in a localisation task: Evidence for extrageniculate mediation. Neuroreport, 13, 655-658.
17. Driver, J., Baylis, G. C., Goodrich, S. J., & Rafal, R. D. (1994). Axis-based neglect of visual shapes. Neuropsychologia, 32, 1353-1365.
18. Driver, J., Baylis, G., & Rafal, R. (1993). Preserved figure-ground segmentation and symmetry perception in a patient with neglect. Nature, 360, 73-75.
19. Driver, J., & Halligan, P. W. (1991). Can visual neglect operate in object-centered coordinates? An affirmative single case study. Cognitive Neuropsychology, 8, 475-494.
20. Fendrich, R., Wessinger, C. M., & Gazzaniga, M. S. (1992). Residual vision in a scotoma: Implications for blindsight [see comments]. Science, 258, 1489-1491.
21. Ferber, S., & Karnath, H. O. (2001). How to assess spatial neglect - line bisection or cancellation tasks? Journal of Clinical and Experimental Neuropsychology, 23, 599-607.
22. Fries, W. (1981). The projection from the lateral geniculate nucleus to the prestriate cortex in macaque monkeys. Proceedings of the Royal Society of London B, 213, 73-86.
23. Gallant, J. L., Braun, J., & Van Essen, D. C. (1993). Selectivity for polar, hyperbolic, and Cartesian gratings in macaque visual cortex. Science, 259, 100-103.
24. Goodale, M. A., & Milner, A. D. (1992). Separate visual pathways for perception and action. Trends in Neurosciences, 15, 20-25.
25. Graziano, M. S. A., Yap, G. S., & Gross, C. G. (1994). Coding of visual space by premotor neurons. Science, 266, 1054-1057.
26. Hallett, M. (2000). Transcranial magnetic stimulation and the human brain. Nature, 406, 147-150.
27. Halligan, P. W., & Marshall, J. C. (1988). How long is a piece of string? A study of line bisection in a case of visual neglect. Cortex, 24, 321-328.
28. Holmes, G. (1918). Disturbances of vision by cerebral lesions. British Journal of Ophthalmology, 2, 353-384.
29. Hubel, D. H., & Wiesel, T. N. (1977). Ferrier lecture. Functional architecture of macaque monkey visual cortex. Proceedings of the Royal Society of London B Biological Science, 198, 1-59.
30. Jahanshahi, M., & Rothwell, J. (2000). Transcranial magnetic stimulation studies of cognition: an emerging field. Experimental Brain Research, 131, 1-9.
31. Kaas, J. H., & Huerta, M. F. (1988). The subcortical visual system of primates. In H. Steklis & J. Erwin (Eds.), Comparative primate biology: Vol. 4. Neurosciences (pp. 327-391). New York: Wiley-Liss.
32. Kasten, E., Poggel, D. A., & Sabel, B. A. (2000). Computer-based training of stimulus detection improves color and simple pattern recognition in the defective field of hemianopic subjects. Journal of Cognitive Neuroscience, 12, 1001-1012.
33. Kasten, E., Wust, S., Behrens-Baumann, W., & Sabel, B. A. (1998). Computer-based training for the treatment of partial blindness. Natural Medicine, 4, 1083-1087.
34. Kentridge, R. W., Heywood, C. A., & Weiskrantz, L. (1997). Residual vision in multiple retinal locations within a scotoma: Implications for blindsight. Journal of Cognitive Neuroscience, 9, 191-202.
35. Kentridge, R. W., Heywood, C. A., & Weiskrantz, L. (1999). Attention without awareness in blindsight. Proceedings of Biological Science, 266, 1805-1811.
36. Kerkhoff, G., Munssinger, U., & Meier, E. K. (1994). Neurovisual rehabilitation in cerebral blindness. Archives of Neurology, 51, 474-481.
37. Klein, R. (2000). Inhibition of return: What, where, when, why and how. Trends in Cognitive Sciences, 4, 138-147.
38. Kustov, A. A., & Robinson, D. L. (1996). Shared neural control of attentional shifts and eye movements. Nature, 384, 74-77.
39. Marzi, C. A., Tassinari, G., Aglioti, S., & Lutzemberger, L. (1986). Spatial summation across the vertical meridian in hemianopics: A test of blindsight. Neuropsychologia, 24, 749-758.
40. McGlinchey-Berroth, R., Milberg, W. P., Verfaellie, M., Alexander, M., & Kilduff, P. T. (1993). Semantic processing in the neglected visual field: Evidence from a lexical decision task. Cognitive Neuropsychology, 10, 79-108.
41. Milner, A. D., & Goodale, M. A. (1995). The visual brain in action (Vol. 27). Oxford; New York: Oxford University Press.
42. Mohler, C. W., & Wurtz, R. H. (1977). Role of striate cortex and superior colliculus in visual guidance of saccadic eye movements in monkeys. Journal of Neurophysiology, 40, 74-94.
43. Morland, A. B., Le, S., Carroll, E., Hoffmann, M. B., & Pambakian, A. (2004). The role of spared calcarine cortex and lateral occipital cortex in the responses of human hemianopes to visual motion. Journal of Cognitive Neuroscience, 16, 204-218.
44. Munoz, D. P., & Wurtz, R. H. (1995). Saccade-related activity in monkey superior colliculus. I. Characteristics of burst and buildup cells. Journal of Neurophysiology, 73, 2313-2333.
45. Nadeau, S. E., & Heilman, K. M. (1991). Gaze-dependent hemianopia without hemispatial neglect. Neurology, 41, 1244-1250.
46. Pambakian, A. L., & Kennard, C. (1997). Can visual function be restored in patients with homonymous hemianopia? British Journal of Ophthalmology, 81, 324-328.
47. Pambakian, A. L., Mannan, S. K., Hodgson, T. L., & Kennard, C. (2004). Saccadic visual search training: A treatment for patients with homonymous hemianopia. Journal of Neurology, Neurosurgery and Psychiatry, 75, 1443-1448.
48. Peli, E. (2000). Field expansion for homonymous hemianopia by optically induced peripheral exotropia. Optometry and Vision Science, 77, 453-464.
49. Perenin, M. T., & Jeannerod, M. (1975). Residual vision in cortically blind hemifields. Neuropsychologia, 13, 1-7.
50. Perenin, M. T., & Jeannerod, M. (1978). Visual function within the hemianopic field following early cerebral hemidecortication in man - I. Spatial localization. Neuropsychologia, 16, 1-13.
51. Poppel, E., Held, R., & Frost, D. (1973). Residual visual function after brain wounds involving the central visual pathways in man. Nature, 243, 295-296.
52. Posner, M. I., & Cohen, Y. (1980). Attention and the control of movements. In J. Requin (Ed.), Tutorials in motor behavior (pp. 243-258). Amsterdam: North Holland.
53. Posner, M. I., Walker, J. A., Friedrich, F. J., & Rafal, R. D. (1987). How do the parietal lobes direct covert attention? Neuropsychologia, 25, 135-146.
54. Rafal, R., Danziger, S., Grossi, G., Machado, L., & Ward, R. (2002). Visual detection is gated by attending for action: Evidence from hemispatial neglect. Proceedings of the National Academy of Science USA, 26, 26.
55. Rafal, R. D., Posner, M. I., Friedman, J. H., Inhoff, A. W., & Bernstein, E. (1988). Orienting of visual attention in progressive supranuclear palsy. Brain, 111, 267-280.
56. Rafal, R., Smith, J., Krantz, J., Cohen, A., & Brennan, C. (1990). Extrageniculate vision in hemianopic humans: Saccade inhibition by signals in the blind field. Science, 250, 118-121.
57. Ro, T., Noser, E., Boake, C., Wallace, R., Gaber, M., Bernstein, M., Speroni, A., De Joya, A., Burgin, S. W., Zhang, L., Grotta, J., & Levin, H. (in press). Functional reorganization and recovery after constraint induced movement therapy in acute stroke: Case reports. Neurocase.
58. Ro, T., Shelton, D., Lee, O. L., & Chang, E. (2004). Extrageniculate mediation of unconscious vision in transcranial magnetic stimulation-induced blindsight. Proceedings of the National Academy of Science USA, 101, 9933-9935.
59. Robertson, E. M., Theoret, H., & Pascual-Leone, A. (2003). Studies in cognition: The problems solved and created by transcranial magnetic stimulation. Journal of Cognitive Neuroscience, 15, 948-960.
60. Robinson, D. L., & Kertzman, C. (1995). Covert orienting of attention in macaques. III. Contributions of the superior colliculus. Journal of Neurophysiology, 74, 713-721.
61. Robinson, D. L., & McClurkin, J. W. (1989). The visual superior colliculus and pulvinar. Reviews of Oculomotor Research, 3, 337-360.
62. Rossi, P. W., Kheyfets, S., & Reding, M. J. (1990). Fresnel prisms improve visual perception in stroke patients with homonymous hemianopia or unilateral visual neglect. Neurology, 40, 1597-1599.
63. Schendel, K., & Robertson, L. C. (2004). Reaching out to see: Arm position can attenuate human visual loss. Journal of Cognitive Neuroscience, 16, 935-943.
64. Sincich, L. C., Park, K. F., Wohlgemuth, M. J., & Horton, J. C. (2004). Bypassing V1: A direct geniculate input to area MT. Nature Neuroscience, 7, 1123-1128.
65. Sprague, J. M. (1966). Interaction of cortex and superior colliculus in mediation of peripherally summoned behavior in the cat. Science, 153, 1544-1547.
66. Stoerig, P., & Cowey, A. (1989). Wavelength sensitivity in blindsight. Nature, 342, 916-918.
67. Stoerig, P., & Cowey, A. (1991). Increment-threshold spectral sensitivity in blindsight. Evidence for colour opponency. Brain, 1487-1512.
68. Stoerig, P., & Cowey, A. (1997). Invited review. Blindsight in man and monkey. Brain, 120, 535-559.
69. Stoerig, P., Kleinschmidt, A., & Frahm, J. (1998). No visual responses in denervated V1: High-resolution functional magnetic resonance imaging of a blindsight patient. Neuroreport, 9, 21-25.
70. Taub, E., Harger, M., Grier, H. C., & Hodos, W. (1980). Some anatomical observations following chronic dorsal rhizotomy in monkeys. Neuroscience, 5, 389-401.
71. Taub, E., Heitmann, R. D., & Barro, G. (1977). Alertness, level of activity, and purposive movement following somatosensory deafferentation in monkeys. Annals of the New York Academy Science, 290, 348-365.
72. Tomaiuolo, F., Ptito, M., Marzi, C. A., Paus, T., & Ptito, A. (1997). Blindsight in hemispherectomized patients as revealed by spatial summation across the vertical meridian. Brain, 120(Pt 5), 795-803.
73. Tootell, R. B., Silverman, M. S., Switkes, E., & De Valois, R. L. (1982). Deoxyglucose analysis of retinotopic organization in primate striate cortex. Science, 218, 902-904.
74. Walker, R., Mannan, S., Maurer, D., Pambakian, A. L., & Kennard, C. (2000). The oculomotor distractor effect in normal and hemianopic vision. Proceedings of the Royal Society of London B Biological Science, 267, 431-438.
75. Walsh, V., & Cowey, A. (2000). Transcranial magnetic stimulation and cognitive neuroscience. Nature Reviews Neuroscience, 1, 73-79.
76. Weiskrantz, L., Warrington, E. K., Sanders, M. D., & Marshall, J. (1974). Visual capacity in the hemianopic field following a restricted occipital ablation. Brain, 97, 709-728.
77. Wessinger, C. M., Fendrich, R., & Gazzaniga, M. S. (1997). Islands of residual vision in hemianopic patients. Journal of Cognitive Neuroscience, 9, 203-221.
78. Williams, C., Azzopardi, P., & Cowey, A. (1995). Nasal and temporal retinal ganglion cells projecting to the midbrain: Implications for "Blindsight". Neuroscience, 65, 577-586.
79. Yukie, M., & Iwai, E. (1981). Direct projection from the dorsal lateral geniculate nucleus to the prestriate cortex in macaque monkeys. Journal of Comparative Neurology, 201, 81-97.
80. Zeki, S. (1980). The representation of colours in the cerebral cortex. Nature, 284, 412-418.
81. Zeki, S., & Ffytche, D. H. (1998). The Riddoch syndrome: Insights into the neurobiology of conscious vision. Brain, 121(Pt 1), 25-45.
82. Zihl, J. (1980). Blindsight: Improvment of visually guided eye movements by systematic practice in patients with cerebral blindness. Neuropsychologia, 18, 71-77.
83. Zihl, J. (1981). Recovery of visual functions in patients with cerebral blindness. Effect of specific practice with saccadic localization. Experimental Brain Research, 44, 159-169.
84. Zihl, J. (2000). Rehabilitation of visual disorders after brain injury. UK: Psychology Press Ltd.
85. Zihl, J., & von Cramon, D. (1979). Restitution of visual function in patients with cerebral blindness. Journal of Neurology, Neurosurgery and Psychiatry, 42, 312-322.
86. Zihl, J., & von Cramon, D. (1985). Visual field recovery from scotoma in patients with postgeniculate damage. A review of 55 cases. Brain, 108(Pt 2), 335-365.