Analysis of anisodine and its metabolites in rat plasma by liquid chromatography-tandem mass spectrometry

Yaoxue Xuebao

Volumn 41, Issue 6, 2006, Pages 518-521

  Chen, Huai Xia ^a   Du, Peng ^a   Han, Feng Mei ^a   Chen, Yong ^a  

^a HUBEI UNIVERSITY   (China)

Author keywords

Anisodine; LC MSn; Metabolite

Indexed keywords

ANISODINE; SCOPOLAMINE DERIVATIVE;

ANGIOSPERM; ANIMAL; ARTICLE; CHEMISTRY; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; MEDICINAL PLANT; METABOLISM; METHODOLOGY; ORAL DRUG ADMINISTRATION; RAT; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; CHROMATOGRAPHY, LIQUID; PLANTS, MEDICINAL; RATS; RATS, WISTAR; SCOPOLAMINE DERIVATIVES; SENSITIVITY AND SPECIFICITY; SOLANACEAE; TANDEM MASS SPECTROMETRY;

EID: 33746798174     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Zhang WS, Li AL. Medicinal Chemistry [M]. Beijing: Higher Education Press, 1999: 236-240, 42-74.
2. Xia Y, Jiang CG. The experiment studies and clinic application development of tropane alkaloids [J]. J Microcirc Technol, 1994, 2:104-107.
3. Chen Y, Chen HX, Du P, et al. HPLC-electrospray ionization ion trap tandem mass spectrometry analysis of oxymatrine and its metabolites in rat urine [J]. Acta Pharm Sin, 2004, 40:740-745.
4. Chan SA, Chen MJ, Liu TY, et al. Determination of aristolchic acid in medicinal plant and herbal product by liquid chromatography-electrospray-ion trap mass spectrometry [J]. Talanta, 2003, 60:679-685.
5. Lam W, Ramanathan R. In electrospray ionization source hydrogen/deuterium exchange LC-MS and LC-MS/MS for characterization of metabolites [J]. J Am Soc Mass Spectrom, 2002,13:345-353.
6. Cong PZ. The Application of Mass Spectrometry in Natural Organic Chemistry [M]. Beijing: Science Press, 1987:406-407.