Effect of KATP+ channel inhibition on total and regional vascular resistance in guinea pig pregnancy

American Journal of Physiology

Volumn 275, Issue 2 PART 2, 1998, Pages

  Keyes, Linda ^a   Hodman, David M ^b   Curran Everett, Douglas ^c   Morris, Kenneth ^d   Moore, Lorna G ^e  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c Division of Pulmonary Sciences and Critical Care Medicine   (United States)

^d UNIVERSITY OF COLORADO   (United States)

^e UNIVERSITY OF COLORADO   (United States)

Author keywords

Endothelium; Endothelium derived hyperpolarizing factor; Glibenclamide; Ion channels; Nitric oxide; Ovarian hormones; Uterine circulation; Vascular smooth muscle; Vasodilation

Indexed keywords

EID: 33746760409     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1998.275.2.h680     Document Type: Article

References (31)

1. Bell, C., and C. Coffey. Factors influencing oestrogen-induced sensitization to acetylcholine of guinea-pig uterine artery. J. Reprod. Fertil. 66:133-137,1982.
2. + channel messenger RNA in rat myometrium during oestrus cycle and in pregnancy. Nature 330:373-375,1987.
3. Chen, G., H. Suzuki, and A. H. Weston. Acetylcholine releases EDHF and EDRF from rat blood vessels. Br. J. Pharmacol. 95:1165-1174,1988.
4. Cornfield, D. N., J. A. McQueston, I. F. McMurtry, D. M. Rodman, and S. H. Abman. Role of ATP-sensitive potassium channels in ovine fetal pulmonary vascular tone. Am. J. Physiol. 263 (Heart Circ. Physiol. 32): H1363-H1368,1992.
5. Curran-Everett, D., K. Morris, and L. G. Moore. Regional circulatory contributions to the increased systemic vascular conductance of pregnancy. Am. J. Physiol. 261 (Heart Circ. Physiol. 30): H1842-H1847,1991.
6. Daut, J., W. Maier-Rudolph, N. Von Beckerath, G. Mehrke, K. Günther, and L. Goedel-Meinen. Hypoxie dilation of coronary arteries is mediated by ATP-sensitive potassium channels. Science 247:1341-1344,1990.
7. + channels. Pflügers Arch. 414: S80-S87,1989.
8. Eichinger, M. R., T. C. Resta, D. S. Balderrama, G. M Herrera, L. A. Richardson, J. M. Resta, and B. R. Walker. Glibenclamide does not reverse attenuated vasoreactivity to acute or chronic hypoxia. J. Appl. Physiol. 79:1173-1180,1995.
9. Harrison, G. L., and L. G. Moore. Blunted vasoreactivity in pregnant guinea pigs is not restored by meclofenamate. Am. J. Obstet. Gynecol. 160:258-264,1989.
10. Hart, M. V., F. D. Hosenpud, A. Roger Hohimer, and M. J. Morton. Hemodynamics during pregnancy and sex steroid administration in guinea pigs. Am. J. Physiol. 249 (Regulatory Integrative Comp. Physiol. 18): R179-R185,1985.
11. Hassessian, H., P. Bodin, and G. Burnstock. Blockade by glibenclamide of the flow-evoked endothelial release of ATP that contributes to vasodilatation in the pulmonary vascular bed of the rat. Br. J. Pharmacol. 109:466-472,1993.
12. + channel blockers on vascular tone in the perfused rat lung. Am. Rev. Respir. Dis. 144:884-887,1991.
13. + channels in vasodilation induced by nitroglycerin, acetylcholine and nitric oxide. J. Pharmacol. Exp. Ther. 267:1327-1335,1993.
14. Kim, T. H., C. P. Weiner, and L. P. Thompson. Effect of pregnancy on contraction and endothelium-mediated relaxation of renal and mesenteric arteries. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H41-H47,1994.
15. Meyer, M. C., J. E. Brayden, and M. K. McLaughlin. Characteristics of vascular smooth muscle in the maternal resistance circulation during pregnancy in the rat. Am. J. Obstet. Gynecol. 169:1510-1516,1993.
16. +-channels. Am. J. Physiol. 260 (Heart Circ. Physiol. 29): H957-H966,1991.
17. + channels in porcine coronary artery smooth muscle cells. Biochem. Biophys. Res. Commun. 181: 700-706,1991.
18. Myers, S. A., J. W. Sparks, E. L. Makowski, G. Meschia, F. C. Battaglia. Relationship between placental blood flow and placental and fetal size in guinea pig. Am. J. Physiol. 243 (Heart Circ. Physiol. 12): H404-H409,1982.
19. Nathan, L., J. Cuevas, and G. Chaudhuri. The role of nitric oxide in the altered vascular reactivity of pregnancy in the rat. Br. J. Pharmacol. 114:955-960,1995.
20. Nelson, M. T., J. B. Patlak, J. F. Worley, and N. B. Standen. Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone. Am. J. Physiol. 259 (Cell Physiol. 28): C3-C18,1990.
21. Nichols, C. G., and W. J. Lederer. Adenosine triphosphatesensitive potassium channels in the cardiovascular system. Am. J. Physiol. 261 (Heart Circ. Physiol. 30): -H1675-H1686, 1991. '
22. Poston, L., A. L. McCarthy, and J. M. Ritter. Control of vascular resistance in the maternal and feto-placental arterial beds. Pharmacol. Ther. 65:215-239,1995.
23. + channel mRNA in rat uterus. Neuron 4: 807-812,1990.
24. + channel openers, diazoxide and cromakalim, and their inhibition by glibenclamide. J. Pharmacol. Exp. Ther. 250: 261-271,1989.
25. + openers, a class of drugs with vasorelaxant and cardioprotective properties. Life Sei. 47:1693-1705,1990.
26. St. Louis, J., and B. Sicotte. Prostaglandin- or endotheliummediated vasodilation is not involved in the blunted responses of blood vessels to vasoconstrictors in pregnant rats. Am. J. Obstet. Gynecol. 166: 684-692,1992.
27. + channels in arterial smooth muscle. Science 245:177-180,1989.
28. Umans, J. G., M. D. Lindheimer, and W. M. Barron. Pressor effect of endothelium-derived relaxing factor inhibition in conscious virgin and gravid rats. Am. J. Physiol. 259 (Renal Fluid Electrolyte Physiol. 28): F292-F296,1990.
29. Weiner, C. P., R. G. Knowles, and S. Moncada. Induction of nitric oxide synthases early in pregnancy. Am. J. Obstet. Gynecol. 171:838-843,1994.
30. Weiner, C. P., K. Z. Liu, L. Thompson, J. Herrig, and D. Chestnut. Effect of pregnancy on endothelium and smooth muscle: their role in reduced adrenergic sensitivity. Am. J. Physiol. 261 (Heart Circ. Physiol. 30): H1275-H1283,1991.
31. Weiner, C. P., E. Martinez, L. K. Zhu, A. Ghodsi, and D. Chestnut. In vitro release of endothelium-derived relaxing factor by acetylcholine is increased during guinea pig pregnancy. Am. J. Obstet. Gynecol. 161:1599-1605,1989.