Mechanotransduction of extracellular signal-regulated kinases 1 and 2 mitogen-activated protein kinase activity in smooth muscle is dependent on the extracellular matrix and regulated by matrix metalloproteinases

American Journal of Pathology

Volumn 169, Issue 2, 2006, Pages 459-470

  Aitken, Karen J ^a   Block, Gregory ^a   Lorenzo, Armando ^a   Herz, Daniel ^a   Sabha, Nesrin ^a   Dessouki, Omar ^a   Fung, France ^a   Szybowska, Marta ^a   Craig, Laura ^a   Bägli, Darius J ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b MDCM   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLADDER; BLADDER DISTENSION; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; EXTRACELLULAR MATRIX; FEMALE; MECHANOTRANSDUCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; SMOOTH MUSCLE;

EID: 33746718746     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2006.050969     Document Type: Article

References (35)

1. Capolicchio G, Aitken KJ, Gu JX, Reddy P, Bagli DJ: Extracellular matrix gene responses in a novel ex vivo model of bladder stretch injury. J Urol 2001, 165:2235-2240
2. Levin R, Levin S, Zhao Y, Buttyan R: Cellular and molecular aspects of bladder hypertrophy. Eur Urol 1997, 32(Suppl 1):15-21
3. Polyakova V, Hein S, Kostin S, Ziegelhoeffer T, Schaper J: Matrix metalloproteinases and their tissue inhibitors in pressure-overloaded human myocardium during heart failure progression. J Am Coll Cardiol 2004, 44:1609-1618
4. Iwanaga Y, Aoyama T, Kihara Y, Onozawa Y, Yoneda T, Sasayama S: Excessive activation of matrix metalloproteinases coincides with left ventricular remodeling during transition from hypertrophy to heart failure in hypertensive rats. J Am Coll Cardiol 2002, 39:1384-1391
5. Sutherland RS, Baskin LS, Elfman F, Hayward SW, Cunha GR: The role of type IV collagenases in rat bladder development and obstruction. Pediatr Res 1997, 41:430-434
6. Peters CA, Freeman MR, Fernandez CA, Shepard J, Wiederschain DG, Moses MA: Dysregulated proteolytic balance as the basis of excess extracellular matrix in fibrotic disease. Am J Physiol 1997, 272:R1960-R1965
7. Pelletier JP, Fernandes JC, Brunet J, Moldovan F, Schrier D, Flory C, Martel-Pelletier J: In vivo selective inhibition of mitogen-activated protein kinase kinase 1/2 in rabbit experimental osteoarthritis is associated with a reduction in the development of structural changes. Arthritis Rheum 2003, 48:1582-1593
8. Daoud S, Schinzel R, Neumann A, Loske C, Fraccarollo D, Diez C, Simm A: Advanced glycation endproducts: activators of cardiac remodeling in primary fibroblasts from adult rat hearts. Mol Med 2001, 7:543-551
9. von Offenberg Sweeney N, Cummins PM, Birney YA, Cullen JP, Redmond EM, Cahill PA: Cyclic strain-mediated regulation of endothelial matrix metalloproteinase-2 expression and activity. Cardiovasc Res 2004, 63:625-634
10. Yang CM, Chien CS, Yao CC, Hsiao LD, Huang YC, Wu CB: Mechanical strain induces collagenase-3 (MMP-13) expression in MC3T3-E1 osteoblastic cells. J Biol Chem 2004, 279:22158-22165
11. Nguyen H, Adam R, Bride S, Park J, Peters C, Freeman M: Cyclic stretch activates p38 SAPK2-, ErbB2-, and AT1-dependent signaling in bladder smooth muscle cells. Am J Physiol Cell Physiol 2000, 279:C1155-C1167
12. Park JM, Adam RM, Peters CA, Guthrie PD, Sun Z, Klagsbrun M, Freeman MR: AP-1 mediates stretch-induced expression of HB-EGF in bladder smooth muscle cells. Am J Physiol 1999, 277:C294-C301
13. Herz DB, Aitken K, Bagli DJ: Collagen directly stimulates bladder smooth muscle cell growth in vitro: regulation by extracellular regulated mitogen activated protein kinase. J Urol 2003, 170:2072-2076
14. Sabha N, Aitken K, Lorenzo A, Szybowska M, Jairath A, Bägli DJ: MMP-7 and EGF receptor mediate hypoxia-induced Erk1/2 MAPK activation and subsequent proliferation in bladder smooth muscle cells. In Vitro Cell Dev Biol Anim 2006, (in press)
15. Galis ZS, Sukhova GK, Libby P: Microscopic localization of active proteases by in situ zymography: detection of matrix metalloproteinase activity in vascular tissue. FASEB J 1995, 9:974-980
16. Upadhyay J, Aitken KJ, Damdar C, Bolduc S, Bagli DJ: Integrins expressed with bladder extracellular matrix after stretch injury in vivo mediate bladder smooth muscle cell growth in vitro. J Urol 2003, 169:750-755
17. Xu H, Goldfarb M: Multiple effector domains within SNT1 coordinate ERK activation and neuronal differentiation of PC12 cells. J Biol Chem 2001, 276:13049-13056
18. Reusch HP, Chan G, Ives HE, Nemenoff RA: Activation of JNK/SAPK and ERK by mechanical strain in vascular smooth muscle cells depends on extracellular matrix composition. Biochem Biophys Res Commun 1997, 237:239-244
19. Marshall CJ: Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 1995, 80:179-185
20. Levin RM, Monson FC, Haugaard N, Buttyan R, Hudson A, Roelofs M, Sartore S, Wein AJ: Genetic and cellular characteristics of bladder outlet obstruction. Urol Clin N Am 1995, 22:263-283
21. Jaureguizar E, Lopez-Pereira P, Martinez-Urrutia MJ: The valve bladder: etiology and outcome. Curr Urol Rep 2002, 3:115-120
22. Close CE: Urethral valves and potential for healing in very young patients. Am Urol Assoc Update Ser 2000, 19:106-111
23. Mitchell MEaCEC: Early primary valve ablation for posterior urethral valves. Semin Pediatr Surg 1996, 5:66-71
24. Jones PL, Crack J, Rabinovitch M: Regulation of tenascin-C, a vascular smooth muscle cell survival factor that interacts with the alpha v beta 3 integrin to promote epidermal growth factor receptor phosphorylation and growth. J Cell Biol 1997, 139:279-293
25. Jones PL, Jones FS, Zhou B, Rabinovitch M: Induction of vascular smooth muscle cell tenascin-C gene expression by denatured type I collagen is dependent upon a beta3 integrin-mediated mitogen-activated protein kinase pathway and a 122-base pair promoter element. J Cell Sci 1999, 112:435-445
26. Miura S, Ohno I, Suzuki J, Suzuki K, Okada S, Okuyama A, Nawata J, Ikeda J, Shirato K: Inhibition of matrix metalloproteinases prevents cardiac hypertrophy induced by beta-adrenergic stimulation in rats. J Cardiovasc Pharmacol 2003, 42:174-181
27. Shah BH, Yesilkaya A, Olivares-Reyes JA, Chen HD, Hunyady L, Catt KJ: Differential pathways of angiotensin II-induced extracellularly regulated kinase 1/2 phosphorylation in specific cell types: role of heparin-binding epidermal growth factor. Mol Endocrinol 2004, 18:2035-2048
28. Suzuki M, Raab G, Moses MA, Fernandez CA, Klagsbrun M: Matrix metalloproteinase-3 releases active heparin-binding EGF-like growth factor by cleavage at a specific juxtamembrane site. J Biol Chem 1997, 272:31730-31737
29. Hemers E, Duval C, McCaig C, Handley M, Dockray GJ, Varro A: Insulin-like growth factor binding protein-5 is a target of matrix metalloproteinase-7: implications for epithelial-mesenchymal signaling. Cancer Res 2005, 65:7363-7369
30. Lakka SS, Jasti SL, Gondi C, Boyd D, Chandrasekar N, Dinh DH, Olivero WC, Gujrati M, Rao JS: Downregulation of MMP-9 in ERK-mutated stable transfectants inhibits glioma invasion in vitro. Oncogene 2002, 21:5601-5608
31. Tan X, Egami H, Abe M, Nozawa F, Hirota M, Ogawa M: Involvement of MMP-7 in invasion of pancreatic cancer cells through activation of the EGFR mediated MEK-ERK signal transduction pathway. J Clin Pathol 2005, 58:1242-1248
32. Sooranna SR, Engineer N, Loudon JA, Terzidou V, Bennett PR, Johnson MR: The mitogen-activated protein kinase dependent expression of prostaglandin H synthase-2 and interleukin-8 messenger ribonucleic acid by myometrial cells: the differential effect of stretch and interleukin-1{beta}. J Clin Endocrinol Metab 2005, 90:3517-3527
33. Pouyssegur J, Volmat V, Lenormand P: Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling. Biochem Pharmacol 2002, 64:755-763
34. Bissell MJ, Aggeler J: Dynamic reciprocity: how do extracellular matrix and hormones direct gene expression? Prog Clin Biol Res 1987, 249:251-262
35. Bissell MJ, Barcellos-Hoff MH: The influence of extracellular matrix on gene expression: is structure the message? J Cell Sci Suppl 1987, 8:327-343