An in vivo analysis of the herbal compound Essiac®

Anticancer Research

Volumn 26, Issue 4 B, 2006, Pages 3057-3063

  Leonard, Blair J N ^a   Kennedy, Deborah A ^b   Cheng, Fong Chi ^c   Chang, Keng Kuang ^c   Seely, Dugald ^b,d   Mills, Edward ^b,e  

^a UNIVERSITY OF TORONTO   (Canada)

^b CANADIAN COLLEGE OF NATUROPATHIC MEDICINE   (Canada)

^c MDS Pharma Services   (Taiwan)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

^e MCMASTER UNIVERSITY   (Canada)

Author keywords

Complementary and alternative medicine; Essiac ; Herbal compound; Immune modulation; In vivo

Indexed keywords

ALCOHOL; CARBON TETRACHLORIDE; ESSIAC; GLUCOSE; HERBACEOUS AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HYPOGLYCEMIA; IMMUNOMODULATION; IN VIVO STUDY; LIVER INJURY; LIVER PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; PUBLICATION; RAT; STOMACH ULCER;

ANIMALS; BLOOD GLUCOSE; CARBON TETRACHLORIDE POISONING; LIVER DISEASES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED ICR; PLANT EXTRACTS; RATS; RATS, WISTAR; STOMACH ULCER;

EID: 33746691901     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Ashikaga T, Bosompra K, O'Brien P and Nelson L: Use of complementary and alternative medicine by breast cancer patients: prevalence, patterns and communication with physicians. Support Care Cancer 10: 542-548, 2002.
2. Boon H, Stewart M, Kennard MA et al: Use of complementary/alternative medicine by breast cancer survivors in Ontario: prevalence and perceptions. J Clin Oncol 18: 2515-2521, 2000.
3. Richardson MA, Sanders T, Palmer JL, Greisinger A and Singletary SE: Complementary/alternative medicine use in a comprehensive cancer center and the implications for oncology. J Clin Oncol 18: 2505-2514, 2000.
4. Gray RE, Greenberg M, Fitch M, Parry N, Douglas MS and Labrecque M: Perspectives of cancer survivors interested in unconventional therapies. J Psychosoc Oncol 75: 149-171, 1998.
5. Fraser SS and Allen C: Could Essiac® halt cancer? Homemaker's Magazine Summer: 9-42, 1977.
6. Tamayo C, Richardson MA, Diamond S and Skoda I: The chemistry and biological activity of herbs used in Flor-Essence® herbal tonic and Essiac®. Phytother Res: 1-14, 2000.
7. Kaegi E: Unconventional therapies for cancer: 1. Essiac. The Task Force on Alternative Therapies of the Canadian Breast Cancer Research Initiative. CMAJ 158: 897-902, 1998.
8. US Congress OTA: Unconventional Cancer Treatments. Washington, D.C.: US Government Printing Office, pp. 71-75, 1990.
9. Bennett LM, Montgomery JL, Steinberg SM and Kulp KS: Flor-Essence® herbal tonic does not inhibit mammary tumor development in Sprague Dawley rats. Breast Cancer Res Treat 88: 87-93, 2004.
10. Robert A, Nezamis JE, Lancaster C and Hanchar AJ: Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury. Gastroenterology 77: 433-443, 1979.
11. Ho RS and Aranda CG: The influence of 2,2-dimethyl-1(4-methylphenyl)-1- propanone (SaH50-283) on food efficiency in rats. Arch Int Pharmacodyn 237: 98-109, 1979.
12. 4-induced liver injury in the rat. Naunyn-Schmiedberg's Arch Pharmacol 320: 266-271, 1982.
13. Griswold DE, DiLorenzo JA and Calabresi P: Quantification and pharmacological dissection of oxazolone-induced contact sensitivity in the mouse. Cell Immunol 11: 198-204, 1974.
14. Riott I: Immunological Tests in Immunology. London: Mosby Publishing, pp. 25.1-25.4, 1993.
15. Szotakova B, Baliharova V, Lamka J et al: Comparison of in vitro activities of biotransformation enzymes in pig, cattle, goat and sheep. Res Vet Sci 76: 43-51, 2004.
16. Robert A, Nezamis JE, Lancaster C, Davis JP, Field SO and Hanchar AJ: Mild irritants prevent gastric necrosis through "adaptive cytoprotection" mediated by prostaglandins. Am J Physiol 245: 113-121, 1983.
17. Lin CC, Lu JM, Yang JJ, Chuang SC and Ujiie T: Anti-inflammatory and radical scavenge effects of Arctium lappa. Am J Chin Med 24: 127-137, 1996.
18. Swanston-Flatt SK, Day C, Flatt PR, Gould BJ and Bailey CJ: Glycaemic effects of traditional European plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetes Res 10: 69-73, 1989.
19. Kulp KS, Montgomery JL, Nelson DO et al: Essiac® and Flor-Essence® herbal tonics stimulate the in vitro growth of human breast cancer cells. Breast Cancer Res Treat. Mar 16, 2006 [Epubl ahead of print].