메뉴 건너뛰기




Volumn 84, Issue 8, 2006, Pages 628-634

Prohormone convertases differentially process pro-neurotensin/neuromedin N in tissues and cell lines

Author keywords

Neurotensin; Pro neurotensin processing; Prohormone convertases

Indexed keywords

CARBOXYPEPTIDASE H; NEUROMEDIN N; NEUROTENSIN; PROPROTEIN CONVERTASE 1; PROPROTEIN CONVERTASE 2; PROPROTEIN CONVERTASE 5;

EID: 33746667184     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-006-0044-6     Document Type: Review
Times cited : (18)

References (35)
  • 1
    • 0015821329 scopus 로고
    • The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami
    • Carraway RE, Leeman SE (1973) The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami. J Biol Chem 248:6854-6861
    • (1973) J Biol Chem , vol.248 , pp. 6854-6861
    • Carraway, R.E.1    Leeman, S.E.2
  • 2
    • 0017191913 scopus 로고
    • Isolation of a tridecapeptide from bovine intestinal tissue and its partial characterization as neurotensin
    • Kitabgi P, Carraway R, Leeman SE (1976) Isolation of a tridecapeptide from bovine intestinal tissue and its partial characterization as neurotensin. J Biol Chem 251:7053-7058
    • (1976) J Biol Chem , vol.251 , pp. 7053-7058
    • Kitabgi, P.1    Carraway, R.2    Leeman, S.E.3
  • 3
    • 0021179691 scopus 로고
    • Neuromedin N: A novel neurotensin like peptide identified in porcine spinal cord
    • Minamino N, Kangawa K, Matsuo H (1984) Neuromedin N: a novel neurotensin like peptide identified in porcine spinal cord. Biochem Biophys Res Commun 120:542-549
    • (1984) Biochem Biophys Res Commun , vol.120 , pp. 542-549
    • Minamino, N.1    Kangawa, K.2    Matsuo, H.3
  • 4
    • 0036771038 scopus 로고    scopus 로고
    • Targeting neurotensin receptors with agonists and antagonists for therapeutic purposes
    • Kitabgi P (2002) Targeting neurotensin receptors with agonists and antagonists for therapeutic purposes. Curr Opin Drug Discov Dev 5:764-776
    • (2002) Curr Opin Drug Discov Dev , vol.5 , pp. 764-776
    • Kitabgi, P.1
  • 5
    • 0000755656 scopus 로고
    • Cloning and sequencing of cDNA for the canine neurotensin/neuromedin N precursor
    • U S A
    • Dobner PR, Barber D, Villa-Komaroff L, McKiernan C (1987) Cloning and sequencing of cDNA for the canine neurotensin/neuromedin N precursor. Proc Natl Acad Sci U S A 84:3516-3520
    • (1987) Proc Natl Acad Sci , vol.84 , pp. 3516-3520
    • Dobner, P.R.1    Barber, D.2    Villa-Komaroff, L.3    McKiernan, C.4
  • 6
    • 0023878936 scopus 로고
    • The rat gene encoding neurotensin and neuromedin N: Structure, tissue specific expression, and evolution of exon sequences
    • Kislauskis E, Bullock B, McNeil S, Dobner PR (1988) The rat gene encoding neurotensin and neuromedin N: structure, tissue specific expression, and evolution of exon sequences. J Biol Chem 263:4963-4968
    • (1988) J Biol Chem , vol.263 , pp. 4963-4968
    • Kislauskis, E.1    Bullock, B.2    McNeil, S.3    Dobner, P.R.4
  • 7
    • 0027399782 scopus 로고
    • Immunological and biochemical characterization of processing products from the neurotensin/neuromedin N precursor in the rat medullary thyroid carcinoma 6-23 cell line
    • Bidard JN, de Nadai F, Rovère C, Moinier D, Laur J, Martinez J, Cuber JC, Kitabgi P (1993) Immunological and biochemical characterization of processing products from the neurotensin/neuromedin N precursor in the rat medullary thyroid carcinoma 6-23 cell line. Biochem J 291:225-233
    • (1993) Biochem J , vol.291 , pp. 225-233
    • Bidard, J.N.1    De Nadai, F.2    Rovère, C.3    Moinier, D.4    Laur, J.5    Martinez, J.6    Cuber, J.C.7    Kitabgi, P.8
  • 8
    • 0025945202 scopus 로고
    • Purification of large neuromedin N (NMN) from canine intestine and its identification as NMN-125
    • Carraway RE, Mitra SP (1991) Purification of large neuromedin N (NMN) from canine intestine and its identification as NMN-125. Biochem Biophys Res Commun 179:301-308
    • (1991) Biochem Biophys Res Commun , vol.179 , pp. 301-308
    • Carraway, R.E.1    Mitra, S.P.2
  • 9
    • 0035794132 scopus 로고    scopus 로고
    • The role of dibasic residues in prohormone sorting to the regulated secretory pathway: A study with proneurotensin
    • Feliciangeli S, Kitabgi P, Bidard JN (2001) The role of dibasic residues in prohormone sorting to the regulated secretory pathway: a study with proneurotensin. J Biol Chem 276: 6140-6150
    • (2001) J Biol Chem , vol.276 , pp. 6140-6150
    • Feliciangeli, S.1    Kitabgi, P.2    Bidard, J.N.3
  • 10
    • 0027049753 scopus 로고
    • Posttranslational processing of the neurotensin/neuromedin N precursor
    • Carraway RE, Mitra SP, Spaulding G (1992) Posttranslational processing of the neurotensin/neuromedin N precursor. Ann NY Acad Sci 668:1-16
    • (1992) Ann NY Acad Sci , vol.668 , pp. 1-16
    • Carraway, R.E.1    Mitra, S.P.2    Spaulding, G.3
  • 11
    • 0027074957 scopus 로고
    • Biosynthesis, maturation, release and degradation of neurotensin and neuromedin N
    • Kitabgi P, de Nadai F, Rovere C, Bidard JN (1992) Biosynthesis, maturation, release and degradation of neurotensin and neuromedin N. Ann NY Acad Sci 668:30-42
    • (1992) Ann NY Acad Sci , vol.668 , pp. 30-42
    • Kitabgi, P.1    De Nadai, F.2    Rovere, C.3    Bidard, J.N.4
  • 12
    • 0028177888 scopus 로고
    • Post-translational processing of the neurotensin/neuromedin N precursor in the central nervous system of the rat-I: Biochemical characterization of maturation products
    • de Nadai F, Rovère C, Bidard JN, Cuber JC, Beaudet A, Kitabgi P (1994) Post-translational processing of the neurotensin/neuromedin N precursor in the central nervous system of the rat-I: biochemical characterization of maturation products. Neuroscience 60:159-166
    • (1994) Neuroscience , vol.60 , pp. 159-166
    • De Nadai, F.1    Rovère, C.2    Bidard, J.N.3    Cuber, J.C.4    Beaudet, A.5    Kitabgi, P.6
  • 13
    • 0028213447 scopus 로고
    • Post-translational processing of the neurotensin/neuromedin N precursor in the central nervous system of the rat-II: Immunohistochemical localization of maturation products
    • Woulfe J, Lafortune L, de Nadai F, Kitabgi P, Beaudet A (1994) Post-translational processing of the neurotensin/neuromedin N precursor in the central nervous system of the rat-II: immunohistochemical localization of maturation products. Neuroscience 60:167-181
    • (1994) Neuroscience , vol.60 , pp. 167-181
    • Woulfe, J.1    Lafortune, L.2    De Nadai, F.3    Kitabgi, P.4    Beaudet, A.5
  • 14
    • 0025964154 scopus 로고
    • Marked variations of the relative distributions of neurotensin and neuromedin N in micropunched rat brain areas suggest differential processing of their common precursor
    • Kitabgi P, Masuo Y, Nicot A, Berod A, Cuber JC, Rostène W (1991) Marked variations of the relative distributions of neurotensin and neuromedin N in micropunched rat brain areas suggest differential processing of their common precursor. Neurosci Lett 124:9-12
    • (1991) Neurosci Lett , vol.124 , pp. 9-12
    • Kitabgi, P.1    Masuo, Y.2    Nicot, A.3    Berod, A.4    Cuber, J.C.5    Rostène, W.6
  • 15
    • 0025288580 scopus 로고
    • Differential processing of neurotensin/neuromedin N precursor(s) in canine brain and intestine
    • Carraway RE, Mitra SP (1990) Differential processing of neurotensin/neuromedin N precursor(s) in canine brain and intestine. J Biol Chem 265:8627-8631
    • (1990) J Biol Chem , vol.265 , pp. 8627-8631
    • Carraway, R.E.1    Mitra, S.P.2
  • 17
    • 0027520778 scopus 로고
    • Biosynthesis and posttranslational processing of the neurotensin/ neuromedin N precursor in the rat medullary thyroid carcinoma 6-23 cell line: Effect of dexamethasone
    • de Nadai F, Rovère C, Bidard JN, Laur J, Martinez J, Cuber JC, Kitabgi P (1993) Biosynthesis and posttranslational processing of the neurotensin/neuromedin N precursor in the rat medullary thyroid carcinoma 6-23 cell line: effect of dexamethasone. Endocrinology 132:1614-1620
    • (1993) Endocrinology , vol.132 , pp. 1614-1620
    • De Nadai, F.1    Rovère, C.2    Bidard, J.N.3    Laur, J.4    Martinez, J.5    Cuber, J.C.6    Kitabgi, P.7
  • 18
    • 0028025283 scopus 로고
    • BON cells display the intestinal pattern of neurotensin/neuromedin N precursor processing
    • Carraway RE, Mitra SP, Evers BM, Townsend CM Jr (1994) BON cells display the intestinal pattern of neurotensin/neuromedin N precursor processing. Regul Pept 53:17-29
    • (1994) Regul Pept , vol.53 , pp. 17-29
    • Carraway, R.E.1    Mitra, S.P.2    Evers, B.M.3    Townsend Jr., C.M.4
  • 19
    • 0025279220 scopus 로고
    • Mutually dependent response elements in the cis-regulatory region of the neurotensin/neuromedin N gene integrate environmental stimuli in PC12 cells
    • Kislauskis E, Dobner PR (1990) Mutually dependent response elements in the cis-regulatory region of the neurotensin/neuromedin N gene integrate environmental stimuli in PC12 cells. Neuron 4:783-795
    • (1990) Neuron , vol.4 , pp. 783-795
    • Kislauskis, E.1    Dobner, P.R.2
  • 20
    • 0027441835 scopus 로고
    • Induction of the neurotensin (NT) gene in PC12 cells gives rise to NT precursor (∼88%), NT(3-13)-like peptide (∼10%), and NT (∼2%)
    • Carraway RE, Bullock BP, Dobner PR (1993) Induction of the neurotensin (NT) gene in PC12 cells gives rise to NT precursor (∼88%), NT(3-13)-like peptide (∼10%), and NT (∼2%). Peptides 14:991-999
    • (1993) Peptides , vol.14 , pp. 991-999
    • Carraway, R.E.1    Bullock, B.P.2    Dobner, P.R.3
  • 21
    • 0027451327 scopus 로고
    • PC12 cells can be induced to produce, but do not process, the neurotensin/neuromedin N precursor
    • Rovère C, de Nadai F, Bidard JN, Cuber JC, Kitabgi P (1993) PC12 cells can be induced to produce, but do not process, the neurotensin/neuromedin N precursor. Peptides 14:983-989
    • (1993) Peptides , vol.14 , pp. 983-989
    • Rovère, C.1    De Nadai, F.2    Bidard, J.N.3    Cuber, J.C.4    Kitabgi, P.5
  • 22
    • 0142248170 scopus 로고    scopus 로고
    • Role of gastrointestinal hormones in the proliferation of normal and neoplastic tissues
    • Thomas RP, Hellmich MR, Townsend CM Jr, Evers BM (2003) Role of gastrointestinal hormones in the proliferation of normal and neoplastic tissues. Endocr Rev 24:571-599
    • (2003) Endocr Rev , vol.24 , pp. 571-599
    • Thomas, R.P.1    Hellmich, M.R.2    Townsend Jr., C.M.3    Evers, B.M.4
  • 24
    • 0029922634 scopus 로고    scopus 로고
    • Evidence that PC2 is the endogenous pro-neurotensin convertase in rMTC 6-23 cells and that PC1- and PC2-transfected PC12 cells differentially process pro-neurotensin
    • Rovère C, Barbero P, Kitabgi P (1996) Evidence that PC2 is the endogenous pro-neurotensin convertase in rMTC 6-23 cells and that PC1- and PC2-transfected PC12 cells differentially process pro-neurotensin. J Biol Chem 271:11368-11375
    • (1996) J Biol Chem , vol.271 , pp. 11368-11375
    • Rovère, C.1    Barbero, P.2    Kitabgi, P.3
  • 25
    • 0032566775 scopus 로고    scopus 로고
    • PC5-A-mediated processing of pro-neurotensin in early compartments of the regulated secretory pathway of PC5-transfected PC12 cells
    • Barbero P, Rovère C, De Bie I, Seidah N, Beaudet A, Kitabgi P (1998) PC5-A-mediated processing of pro-neurotensin in early compartments of the regulated secretory pathway of PC5-transfected PC12 cells. J Biol Chem 273:25339-25346
    • (1998) J Biol Chem , vol.273 , pp. 25339-25346
    • Barbero, P.1    Rovère, C.2    De Bie, I.3    Seidah, N.4    Beaudet, A.5    Kitabgi, P.6
  • 26
    • 0034726655 scopus 로고    scopus 로고
    • Immunohistochemical evidence for the involvement of protein convertases 5A and 2 in the processing of proneurotensin in rat brain
    • Villeneuve P, Lafortune L, Seidah NG, Kitabgi P, Beaudet A (2000) Immunohistochemical evidence for the involvement of protein convertases 5A and 2 in the processing of proneurotensin in rat brain. J Comp Neurol 424:461-475
    • (2000) J Comp Neurol , vol.424 , pp. 461-475
    • Villeneuve, P.1    Lafortune, L.2    Seidah, N.G.3    Kitabgi, P.4    Beaudet, A.5
  • 27
    • 0034626863 scopus 로고    scopus 로고
    • Immunohistochemical evidence for the implication of PC1 in the processing of proneurotensin in rat brain
    • Villeneuve P, Seidah NG, Beaudet A (2000) Immunohistochemical evidence for the implication of PC1 in the processing of proneurotensin in rat brain. Neuroreport 11:3443-3447
    • (2000) Neuroreport , vol.11 , pp. 3443-3447
    • Villeneuve, P.1    Seidah, N.G.2    Beaudet, A.3
  • 28
    • 0036678560 scopus 로고    scopus 로고
    • Altered processing of the neurotensin/neuromedin N precursor in PC2 knock down mice: A biochemical and immunochemical study
    • Villeneuve P, Feliciangeli S, Croissandeau G, Seidah NG, Mbikay M, Kitabgi P, Beaudet A (2002) Altered processing of the neurotensin/neuromedin N precursor in PC2 knock down mice: a biochemical and immunochemical study. J Neurochem 82:783-793
    • (2002) J Neurochem , vol.82 , pp. 783-793
    • Villeneuve, P.1    Feliciangeli, S.2    Croissandeau, G.3    Seidah, N.G.4    Mbikay, M.5    Kitabgi, P.6    Beaudet, A.7
  • 29
    • 0032801426 scopus 로고    scopus 로고
    • Prohormone convertase-1 is essential for conversion of chromogranin A to pancreastatin
    • Udupi V, Lee HM, Kurosky A, Greeley GH Jr (1999) Prohormone convertase-1 is essential for conversion of chromogranin A to pancreastatin. Regul Pept 15:123-127
    • (1999) Regul Pept , vol.15 , pp. 123-127
    • Udupi, V.1    Lee, H.M.2    Kurosky, A.3    Greeley Jr., G.H.4
  • 31
    • 0022519470 scopus 로고
    • Cloning and sequence analysis of cDNA for bovine carboxypeptidase E
    • Fricker LD, Evans CJ, Each FS, Herbert E (1986) Cloning and sequence analysis of cDNA for bovine carboxypeptidase E. Nature 323:461-464
    • (1986) Nature , vol.323 , pp. 461-464
    • Fricker, L.D.1    Evans, C.J.2    Each, F.S.3    Herbert, E.4
  • 33
    • 0029943687 scopus 로고    scopus 로고
    • Impaired processing of brain proneurotensin and promelanin-concentrating hormone in obese fat/fat mice
    • Rovère C, Viale A, Nahon JL, Kitabgi P (1996) Impaired processing of brain proneurotensin and promelanin-concentrating hormone in obese fat/fat mice. Endocrinology 137:2954-2958
    • (1996) Endocrinology , vol.137 , pp. 2954-2958
    • Rovère, C.1    Viale, A.2    Nahon, J.L.3    Kitabgi, P.4
  • 34
    • 0020333709 scopus 로고
    • Neurotensin: Discovery, isolation, characterization, synthesis and possible physiological roles
    • Leeman SE, Carraway RE (1982) Neurotensin: discovery, isolation, characterization, synthesis and possible physiological roles. Ann NY Acad Sci 400:1-16
    • (1982) Ann NY Acad Sci , vol.400 , pp. 1-16
    • Leeman, S.E.1    Carraway, R.E.2
  • 35
    • 0036289542 scopus 로고    scopus 로고
    • Production of recombinant large proneurotensin/neuromedin N-derived peptides and characterization of their binding and biological activity
    • Friry C, Feliciangeli S, Richard F, Kitabgi P, Rovere C (2002) Production of recombinant large proneurotensin/neuromedin N-derived peptides and characterization of their binding and biological activity. Biochem Biophys Res Commun 290:1161-1168
    • (2002) Biochem Biophys Res Commun , vol.290 , pp. 1161-1168
    • Friry, C.1    Feliciangeli, S.2    Richard, F.3    Kitabgi, P.4    Rovere, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.