Combined cannabis/methaqualone withdrawal treated with psychotropic analgesic nitrous oxide

International Journal of Neuroscience

Volumn 116, Issue 7, 2006, Pages 859-869

  Gillman, Mark ^a   Harker, Nadine ^b   Lichtigfeld, Frederick ^a  

^a South African Brain Research Institute   (South Africa)

^b SANCA PE Mercantile Hospital   (South Africa)

Author keywords

Cannabis; Methaqualone; Nitrous oxide; White pipe; Withdrawal

Indexed keywords

CANNABIS; CARBAMAZEPINE; METHAQUALONE; NITROUS OXIDE PLUS OXYGEN; OXAZEPAM; PLACEBO; PSYCHOTROPIC ANALGESIC NITROUS OXIDE; UNCLASSIFIED DRUG;

ADULT; CANNABIS ADDICTION; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; SINGLE BLIND PROCEDURE; SOUTH AFRICA; TREATMENT OUTCOME; WHITE PIPE; WITHDRAWAL SYNDROME;

ADULT; CANNABIS; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; MALE; METHAQUALONE; MIDDLE AGED; NITROUS OXIDE; OUTCOME ASSESSMENT (HEALTH CARE); PSYCHOTROPIC DRUGS; SINGLE-BLIND METHOD; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 33746653029     PISSN: 00207454     EISSN: 15635279     Source Type: Journal    
DOI: 10.1080/00207450600753998     Document Type: Conference Paper

References (37)

1. Alho, H., Methuen, T., Paloheimo, M., Strid, N., Seppa, K., Tiainen, J., Salaspuro, M., & Roine, R. (2002). Long-term effects of and physiological responses to nitrous oxide gas treatment during alcohol withdrawal: A double-blind, placebo-controlled trial. Alcoholism: Clinical Experimental Research, 26, 1816-1822.
2. Alho, H., Metheun, T., Paloheimo, M., Seppä, K., Strid, N., Apter-Kaseva, N., Tiainen, K., Salaspuro, M., & Roine, R. (2003). Nitrous oxide has no effect in the treatment of alcohol withdrawal syndrome: Double-blind placebo-controlled randomized trial. Journal of Clinical Psychopharmacology, 23, 211-214.
3. Carroll, M., & Gallo, G. (1988a). Methaqualone the quest for oblivion. In S. H. Snyder & M. Lader (Eds.), The encyclopedia of psychoactive drugs. (pp. 15-25). London: Burke Publishing Company.
4. Carroll, M., & Gallo, G. (1988b). The encyclopedia of psychoactive drugs. (pp. Ibid. (pp. 15-25; 81-84).
5. Carroll, M., & Gallo, G. (1988c). The encyclopedia of psychoactive drugs. (pp. Ibid. (pp. 51-61).
6. Carroll., M., & Gallo, G. (1988d). The encyclopedia of psychoactive drugs. (pp. Ibid. (pp. 63-69).
7. Clark, M. S., & Brunick, A. (1999). Handbook of Nitrous Oxide and Oxygen Sedation. St. Louis: Mosby.
8. Clark, M. S., Campbell, S. A., & Clark, A. M. (2006). Technique for the administration of nitrous oxide/oxygen sedation to ensure psychotropic analgesic nitrous oxide (PAN) effects. International Journal of Neuroscience, 116, 871-877.
9. Daynes, G., & Gillman, M. A. (1994). Psychotropic analgesic nitrous oxide prevents craving after withdrawal for alcohol, cannabis and tobacco. International Journal of Neuroscience, 76, 13-16.
10. Dworkin, S. F., Schubert, M., Chen, A. C. N., & Clark, D. W. (1986). Psychological preparation influences nitrous oxide analgesia: Replication of laboratory findings in a clinical setting. Oral Surgery Oral Medicine and Oral Pathology, 61, 108-112.
11. Gillman, M. A., & Lichtigfeld, F. J. (1986). Minimal sedation required with nitrous oxide-oxygen treatment of the alcohol withdrawal state. British Journal of Psychiatry, 148, 604-606.
12. Gillman, M. A., & Lichtigfeld, F. J. (1990). Analgesic nitrous oxide for alcohol withdrawal: A critical appraisal after 10 years use. Postgraduate Medical Journal, 66, 543-546.
13. Gillman, M. A., & Lichtigfeld, F. J. (1991a). Placebo and analgesic nitrous oxide for the alcohol withdrawal state. British Journal of Psychiatry, 159, 672-675.
14. Gillman, M. A., & Lichtigfeld, F. J. (1991b). The opioid effects of analgesic (subanesthetic) nitrous oxide on the alcohol withdrawal state. Annals of the New York Academy of Sciences, 625, 784-785.
15. Gillman, M. A., & Lichtigfeld, F. J. (1998). Clinical role and mechanisms of action of analgesic nitrous oxide. International Journal of Neuroscience, 93, 55-62.
16. Gillman, M. A., & Lichtigfeld, F. J. (2002). Randomised double-blind trial of psychotropic analgesic nitrous oxide compared with diazepam for alcohol withdrawal state. Journal of Substance Abuse Treatment, 22, 129-134.
17. Gillman, M. A., & Lichtigfeld, F. J. (2004). Correct use of analgesic nitrous oxide for the alcohol withdrawal state essential. Journal of Clinical Psychopharmacology, 24, 238-239.
18. Gillman, M. A., & Lichtigfeld, F. J. (2006). Psychotropic analgesic nitrous oxide (PAN) as a probe of the endogenous opioid system inman and for treating substance abuse withdrawal. In L. A. Bennet (Ed.), New Topics in Substance Abuse Treatment, (pp. 1-72). New York: Nova Science.
19. Gordon, D. (1992). Mandrax - the drug and the discourse - a case study of Parkwood. Research Report: Sociology Department, University of Cape Town.
20. Griffiths, R. R., & Sannerud, C. A. (1987). Abuse of and dependence on benzodiazepines and other anxiolytic/sedative drugs. In H. Y. Meltzer (Ed.), Psychopharmacology: The third generation of progress. (pp. 1535-1541). New York: Raven Press.
21. Gross, M., Lewis, E., & Nagarajan, M. (1973). An improved quantitative system for assessing the acute alcoholic psychoses and related states (TSA and SSA). In M. Gross (Ed.), Alcohol intoxication and withdrawal: Experimental Studies, Vol. 35. (pp. 365-376). New York: Plenum Press.
22. Gross, M., Lewis, E., & Hastey, J. (1974). Acute alcohol withdrawal syndrome. In B. Kissin & H. Begleiter (Eds.), The biology of alcoholism, Vol. 3. (pp. 191-256). New York: Plenum Press.
23. Karrassellos, C., & Wilson, B. (1993). A South African outpatient drug treatment centre. South African Medical Journal, 83, 337-338.
24. Lichtigfeld, F. J., & Gillman, M. A. (1982). The treatment of alcoholic withdrawal states with oxygen and nitrous oxide. South African Medical Journal, 61, 349-351.
25. Lichtigfeld, F. J., & Gillman, M. A. (1989a). The effect of placebo in the alcohol withdrawal state. Alcohol and Alcoholism, 24, 109-112.
26. Lichtigfeld, F. J., & Gillman, M. A. (1989b). Analgesic nitrous oxide for alcohol withdrawal is better than placebo. International Journal of Neuroscience, 49, 71-74.
27. Lichtigfeld, F. J., & Gillman, M. A. (1996). Role of dopamine mesolimbic system in opioid action of psychotropic analgesic nitrous oxide (PAN) in alcohol and drug withdrawal. Clinical Neuropharmacology, 19, 246-250.
28. Madden, J. S. (1979). A guide to alcohol and drug dependence. Bristol: John Wright & Sons.
29. McCarthy, G., Heiberg, L., & Smith, L. P. (1994). Analysis of street mandrax - clinical implications. 8th National Psychiatry Congress. September 21-23, 1994, Somerset West, South Africa.
30. McCarthy, G., & Myers, B. , (2003). Treatment for mandrax (combination of methaqualone, cannabis and tobacco) dependence in adults (Protocol for a Cochrane Review). In The Cochrane Library, Issue 2. Oxford: Update Software.
31. Ojutkangas, R. in press. A case study of opposition to innovation: Pioneering PAN in Finland for withdrawal. International Journal of Neuroscience,
32. Ojutkangas, R., & Gillman, M. A. (1994). Psychotropic analgesic nitrous oxide for treating alcohol withdrawal in an outpatient setting. International Journal of Neuroscience, 76, 35-39.
33. Parry, C. D. H., Bhana, A., Pluddermann, A., Myers, B., Siegfried, N., Morojelle, N. K., Flisher, A. J., & Kozell, N. J. (2002). The South African Community Epidemiology Network on Drug Use (SACENDU): Description, findings (1997-1999) and policy implications. Addiction, 97, 969-976.
34. Pascarelli, E. F. (1973). Methaqualone abuse, the quiet epidemic. Journal of the American Medical Association, 224, 1512-1514.
35. Searll, A. (1989). It can't happen to me. (pp. 70-80). Cape Town: Struik Publishers.
36. Sher, M. L. (1993). An analysis of a variety of illicit methaqualone formulations and an investigation into the effect of smoking on methaqualone present in these formulations, Honours Thesis accepted in part fulfilment for BSc (Honours) Degree UCT. Cape Town, South Africa.
37. Sullivan, J. T., Sykora, K., Schneiderman, J., Naranjo, C. A., & Sellers, E. M. (1989). Assessment of alcohol withdrawal: The revised clinical institute withdrawal assessment for alcohol scale (CIWA-Ar). British Journal of Addiction, 84, 1353-1357.