Disconnection analysis of CA3 and DG in mediating encoding but not retrieval in a spatial maze learning task

Learning and Memory

Volumn 13, Issue 4, 2006, Pages 458-464

  Jerman, Taylor ^a   Kesner, Raymond P ^a   Hunsaker, Michael R ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN DYSFUNCTION; BRAIN REGION; CONTROLLED STUDY; DENTATE GYRUS; HEMISPHERE; HIPPOCAMPUS; INFORMATION PROCESSING; LEARNING; MALE; MAZE TEST; MEMORY CONSOLIDATION; NONHUMAN; PRIORITY JOURNAL; RAT; SHORT TERM MEMORY; TASK PERFORMANCE;

ANIMALS; AXONS; EXCITATORY AMINO ACID AGONISTS; GANGLIA, SPINAL; HIPPOCAMPUS; IBOTENIC ACID; MALE; MAZE LEARNING; MEMORY; NEUROTOXINS; RATS; RATS, LONG-EVANS;

EID: 33746647404     PISSN: 10720502     EISSN: 15495485     Source Type: Journal    
DOI: 10.1101/lm.246906     Document Type: Article

References (26)

1. Gilbert, P.E. and Kesner, R.P. 2003. Localization of function within the hippocampus: The role of the dorsal CA3 subregion in paired-associate learning. Behav. Neurosci. 117: 1385-1394.
2. _.2006. The role of the dorsal CA3 hippocampal subregion in spatial working memory and pattern separation. Behav. Brain Res. 169: 142-149.
3. Gilbert, P.E., Kesner, R.P., and Lee, I. 2001. Dissociating hippocampal subregions: A double dissociation between the dentate gyrus and CA1. Hippocampus 11: 626-636.
4. Goldschmidt, R.B. and Steward, O. 1982. Neurotoxic effects of colchicine: Differential susceptibility of CNS neuronal populations. Neuroscience 7: 695-714.
5. Goodrich-Hunsaker, N.J., Hunsaker, M.R., and Kesner, R.P. 2005. Effects of hippocampus sub-regional lesions for metric and topological spatial information processing. Abstract Viewer/Itinerary Planner, Program No. 647.1. Society for Neuroscience, Washington, D.C.
6. Jerman, T.S., Kesner, R.P., Lee, I., and Berman, R.F. 2005. Patterns of cell loss based on subregional lesions of the hippocampus. Brain Res. 1065: 1-7.
7. Kesner, R.P., Lee, I., and Gilbert, P. 2004. A behavioral assessment of hippocampal function based on a subregional analysis. Rev. Neurosci. 15: 333-351.
8. Lassalle, J.M., Bataille, T., and Halley, H. 2000. Reversible inactivation of the hippocampal mossy fiber synapses in mice impairs spatial learning, but neither consolidation nor memory retrieval, in the Morris navigation task. Neurobiol. Learn. & Mem. 73: 243-257.
9. Lee, I. and Kesner, R.P. 2002. Differential contribution of NMDA receptors in hippocampal subregions to spatial working memory. Nat. Neurosci. 5: 162-168.
10. _.2003. Differential role of dorsal hippocampus subregions in spatial working memory with short versus intermediate delay. Behav. Neurosci. 117: 1044-1053.
11. _.2004a. Differential contributions of dorsal hippocampal subregions to memory acquisition and retrieval in contextual fear-conditioning. Hippocampus 14: 301-310.
12. _.2004b. Encoding versus retrieval of spatial memory: Double dissociation between the dentate gyrus and the perforant path inputs into CA3 in the dorsal hippocampus. Hippocampus 14: 66-76.
13. Leutgeb, S., Leutgeb, J.K., Treves, A., Moser, M.B., and Moser, E.I. 2004. Distinct ensemble codes in hippocampal areas CA3 and CA1. Science 305: 1295-1298.
14. Marr, D. 1971. Simple memory: A theory of archicortex. Phil. Trans. R. Soc. London B 262: 23-81.
15. Mundy, W.R. and Tilson, H.A. 1990. Neurochemical recovery in the neocortex after colchicine lesions of the nucleus basalis magnocellularis in rats. Brain Res. Bull. 25: 207-209.
16. Nakazawa, K., Sun, L.D., Quirk, M.C., Rondi-Reig, L., Wilson, M.A., and Tonegawa, S. 2003. Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience. Neuron 38: 305-315.
17. Nanry, K.P., Mundy, W.R., and Tilson, H.A. 1989. Colchicine-induced alternations of reference memory in rats: Role of spatial versus non-spatial task components. Behav. Brain Res. 35: 45-53.
18. Paxinos, G. and Watson, C. 1998. The rat brain in stereotaxic coordinates. Academic Press, San Diego, CA.
19. Poucet, B. 1989. Object exploration, habituation, and response to a spatial change in rats following septal or medial frontal cortical damage. Behav. Neurosci. 103: 1009-1016.
20. Rabinovitch, M.S. and Rosvold, H.E. 1951. A closed-field intelligence test for rats. Can. J. Psychol. 5: 122-128.
21. Rolls, E.T. 1996. A theory of hippocampal function in memory. Hippocampus 6: 601-620.
22. Sutherland, R.J., Whishaw, I.Q., and Kolb, B. 1983. A behavioural analysis of spatial localization following electrolytic, kainate- or colchicine-induced damage to the hippocampal formation in the rat. Behav. Brain Res. 7: 133-153.
23. Tanila, H. 1999. Hippocampal place cells can develop distinct representations of two visually identical environments. Hippocampus 9: 235-246.
24. Vago, D.R. and Kesner, R.P. 2005. An electrophysiological and behavioral characterization of the temporoammonic pathway: Disruption produces deficits in retrieval and spatial mismatch. Abstract Viewer/Itinerary Planner, Program No. 647.5. Society for Neuroscience, Washington, D.C.
25. Vazdarjanova, A. and Guzowski, J.F. 2004. Differences in hippocampal neuronal population responses to modifications of an environmental context: Evidence for distinct, yet complementary, functions of CA3 and CA1 ensembles. J. Neurosci. 24: 6489-6496.
26. Xavier, G.F., Oliveira-Filho, F.J.B., and Santos, A.M.G. 1999. Dentate gyrus-selective colchicine lesion and disruption of performance in spatial tasks: Difficulties in "place strategy" because of a lack of flexibility in the use of environmental cues? Hippocampus 9: 668-681.