Pepsin and pancreatin performance in the dissolution of crosslinked gelatin capsules from pH 1 to 8

Pharmacopeial Forum

Volumn 30, Issue 3, 2004, Pages 1084-1089

  Gallery, Jean ^a   Han, Jian Hwa ^b   Abraham, Chiramel ^b  

^a ABBOTT LABORATORIES   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33746646361     PISSN: 03634655     EISSN: 15421945     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Gelatin Capsule Working Group, "Collaborative Development of Two-Tiered Dissolution Testing for Gelatin Capsules and Gelatin-Coated Tablets Using Enzyme-Containing Media," Pharmacopeial Forum 24(5): 7045-7050 1998.
2. D.W. Piper and B.H. Fenton, "pH Stability and Activity Curves of Pepsin with Special Reference to Their Clinical Importance," Gut (6): 506-508 1965.
3. Methods in Enzymology, vol. XLIV, Academic Press, Klaus Mosbach, editor, p. 79 1976.
4. The Enzymes, vol. III, Academic Press, Klaus Mosbach, editor, p. 429 1971.
5. Methods in Enzymology, vol. XLIV, Academic Press, Klaus Mosbach, editor, pp. 403-404 1976
6. Thomas B. Gold, Robert G. Bruice, Jr., Robert A. Lodder, and George A. Digenis, "Determination of Extent of Formaldehyde-Induced Crosslinking in Hard Gelatin Capsules by Near-Infrared Spectrophotometry," Pharmaceutical Research 14(8): 1046-1050 1997.