-
1
-
-
0038002981
-
The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: Implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity
-
Ward, BA and Gorski, JC and Jones, DR and Hall, SD and Flockhart, DA and Desta, Z. (2003) The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: Implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity J Pharmacol Exp Ther, 306, pp. 287-300.
-
(2003)
J Pharmacol Exp Ther
, vol.306
, pp. 287-300
-
-
Ward, B.A.1
Gorski, J.C.2
Jones, D.R.3
Hall, S.D.4
Flockhart, D.A.5
Desta, Z.6
-
2
-
-
19944428456
-
Pharmacogenetics of efavirenz and central nervous system side-effects: An Adult AIDS Clinical Trials Group study
-
Haas, DW and Ribaudo, HJ and Kim, RB and Tierney, C and Wilkinson, GR and Gulick, RM and (2004) Pharmacogenetics of efavirenz and central nervous system side-effects: An Adult AIDS Clinical Trials Group study AIDS, 18, pp. 2391-400.
-
(2004)
AIDS
, vol.18
, pp. 2391-2400
-
-
Haas, D.W.1
Ribaudo, H.J.2
Kim, R.B.3
Tierney, C.4
Wilkinson, G.R.5
Gulick, R.M.6
-
3
-
-
20244364148
-
Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients
-
Rotger, M and Colombo, S and Furrer, H and Bleiber, G and Buclin, T and Lee, BL and (2005) Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients Pharmacogenet Genomics, 15, pp. 1-5.
-
(2005)
Pharmacogenet Genomics
, vol.15
, pp. 1-5
-
-
Rotger, M.1
Colombo, S.2
Furrer, H.3
Bleiber, G.4
Buclin, T.5
Lee, B.L.6
-
4
-
-
2942551228
-
Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens
-
Tsuchiya, K and Gatanaga, H and Tachikawa, N and Teruya, K and Kikuchi, Y and Yoshino, M and (2004) Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens Biochem Biophys Res Commun, 319, pp. 1322-6.
-
(2004)
Biochem Biophys Res Commun
, vol.319
, pp. 1322-1326
-
-
Tsuchiya, K.1
Gatanaga, H.2
Tachikawa, N.3
Teruya, K.4
Kikuchi, Y.5
Yoshino, M.6
-
5
-
-
0035808574
-
Efavirenz plasma levels can predict treatment failure and central nervous system side-effects in HIV-1-infected patients
-
Marzolini, C and Telenti, A and Decosterd, LA and Greub, G and Biollaz, J and Buclin, T. (2001) Efavirenz plasma levels can predict treatment failure and central nervous system side-effects in HIV-1-infected patients AIDS, 15, pp. 71-5.
-
(2001)
AIDS
, vol.15
, pp. 71-75
-
-
Marzolini, C.1
Telenti, A.2
Decosterd, L.A.3
Greub, G.4
Biollaz, J.5
Buclin, T.6
-
6
-
-
85043515692
-
Higher efavirenz plasma levels correlate with development of insomnia
-
Nunez, M and Gonzalez, dR and Gallego, L and Jimenez-Nacher, I and Gonzalez-Lahoz, J and Soriano, V. (2001) Higher efavirenz plasma levels correlate with development of insomnia J Acquir Immune Defic Syndr, 28, pp. 399-400.
-
(2001)
J Acquir Immune Defic Syndr
, vol.28
, pp. 399-400
-
-
Nunez, M.1
Gonzalez, D.R.2
Gallego, L.3
Jimenez-Nacher, I.4
Gonzalez-Lahoz, J.5
Soriano, V.6
-
7
-
-
2542549644
-
Efavirenz plasma concentrations in HIV-infected patients: Inter- and intra-individual variability and clinical effects
-
Stahle, L and Moberg, L and Svensson, JO and Sonnerborg, A. (2004) Efavirenz plasma concentrations in HIV-infected patients: Inter- and intra-individual variability and clinical effects Ther Drug Monit, 26, pp. 267-70.
-
(2004)
Ther Drug Monit
, vol.26
, pp. 267-270
-
-
Stahle, L.1
Moberg, L.2
Svensson, J.O.3
Sonnerborg, A.4
-
8
-
-
17644414659
-
Influence of 516G>T polymorphisms at the gene encoding the CYP450-2B6 isoenzyme on efavirenz plasma concentrations in HIV-infected subjects
-
Rodriguez-Novoa, S and Barreiro, P and Rendon, A and Jimenez-Nacher, I and Gonzalez-Lahoz, J and Soriano, V. (2005) Influence of 516G>T polymorphisms at the gene encoding the CYP450-2B6 isoenzyme on efavirenz plasma concentrations in HIV-infected subjects Clin Infect Dis, 40, pp. 1358-61.
-
(2005)
Clin Infect Dis
, vol.40
, pp. 1358-1361
-
-
Rodriguez-Novoa, S.1
Barreiro, P.2
Rendon, A.3
Jimenez-Nacher, I.4
Gonzalez-Lahoz, J.5
Soriano, V.6
-
9
-
-
6344240478
-
Induction of CYP3A4 by efavirenz in primary human hepatocytes: Comparison with rifampin and phenobarbitol
-
Hariparsad, N and Nallani, SC and Sane, RS and Buckley, DJ and Buckley, AR and Desai, PB. (2004) Induction of CYP3A4 by efavirenz in primary human hepatocytes: Comparison with rifampin and phenobarbitol J Clin Pharmacol, 44, pp. 1273-81.
-
(2004)
J Clin Pharmacol
, vol.44
, pp. 1273-1281
-
-
Hariparsad, N.1
Nallani, S.C.2
Sane, R.S.3
Buckley, D.J.4
Buckley, A.R.5
Desai, P.B.6
-
10
-
-
0036335573
-
Hepatic but not intestinal CYP3A4 displays dose-dependent induction by efavirenz in humans
-
Mouly, S and Lown, KS and Kornhauser, D and Joseph, JL and Fiske, WD and Benedek, IH and (2002) Hepatic but not intestinal CYP3A4 displays dose-dependent induction by efavirenz in humans Clin Pharmacol Ther, 72, pp. 1-9.
-
(2002)
Clin Pharmacol Ther
, vol.72
, pp. 1-9
-
-
Mouly, S.1
Lown, K.S.2
Kornhauser, D.3
Joseph, J.L.4
Fiske, W.D.5
Benedek, I.H.6
-
11
-
-
0037032931
-
Diurnal variation of plasma protease inhibitor concentrations
-
Justesen, US and Pedersen, C. (2002) Diurnal variation of plasma protease inhibitor concentrations AIDS, 16, pp. 2487-9.
-
(2002)
AIDS
, vol.16
, pp. 2487-2489
-
-
Justesen, U.S.1
Pedersen, C.2
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