Caloric restriction increases longevity substantially only when the reaction norm is steep

Biogerontology

Volumn 7, Issue 3, 2006, Pages 161-164

  Phelan, John P ^a   Rose, Michael R ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aging; Caloric restriction; Evolution of senescence; Human life extension; Maximum longevity; Phenotypic plasticity; Reaction norms

Indexed keywords

ARTICLE; CALORIC INTAKE; CALORIC RESTRICTION; DIET RESTRICTION; DROSOPHILA; ENVIRONMENTAL PARAMETERS; EVOLUTION; EXPECTATION; EXPERIMENTAL STUDY; FITNESS; GENETIC CONSERVATION; HUMAN; LIFESPAN; LONGEVITY; MAMMAL; NONHUMAN; PHENOTYPIC PLASTICITY; PLESIOMORPHY; PRIMATE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCTION; RODENT; SURVIVAL RATE;

ADAPTATION, PHYSIOLOGICAL; AGING; ANIMALS; BIOLOGICAL EVOLUTION; CALORIC RESTRICTION; EATING; ENVIRONMENT; EVOLUTION; HUMANS; LONGEVITY; MODELS, BIOLOGICAL; SPECIES SPECIFICITY;

EID: 33746618023     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-006-9005-2     Document Type: Article

References (24)

1. Ball ZB, Barnes RH, Visscher MB (1947) The effects of dietary caloric restriction on maturity and senescence, with particular reference to fertility and longevity. Am J Physiol 150:511-519
2. Charlesworth B (1994) Evolution in age-structured populations. 2nd edn. Cambridge University Press, London
3. Chippindale AK, Leroi AM, Kim SB, Rose MR (1993) Phenotypic plasticity and selection in Drosophila life-history evolution. I. Nutrition and the cost of reproduction. J Evol Biol 6:171-193
4. Clancy DJ, Gems D, Harshman LG, Oldham S, Stocker H, Hafen E, Leevers SJ, Partridge L (2001) Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 202:104-106
5. Day T, Rowe L (2002) Developmental thresholds and the evolution of reaction norms for age and size at life-history transitions. Am Nat 159:338-350
6. Ellison PT, Lager C (1986) Moderate recreational running is associated with lowered salivary progesterone profiles in women. Am J Obstet Gynecol 154:1000-1003
7. Gage TB (2003) The evolution of human phenotypic plasticity: Age and nutritional status at maturity. Hum Biol 75:521-537
8. Graves JL (1993) The costs of reproduction and dietary restriction: parallels between insects and mammals. Growth Dev Aging 57:233-249
9. Holehan AM, Merry BJ (1985) Modification of the oestrous cycle hormonal profile by dietary restriction. Mech Ageing Dev 32:63-76 63-76
10. Lager C, Ellison PT (1990) Effect of moderate weight loss on ovarian function assessed by salivary progesterone measurements. Am J Hum Biol 2:303-312
11. Leroi AM, Kim SB, Rose MR (1994) Do phenotypic manipulations reveal evolutionary trade-offs? An experimental test using Drosophila melanogaster. Am Nat 144:661-676
12. Merry BJ, Holehan AM (1981) Serum profiles of LH, FSH, testosterone and 5?-DHT from 21 to 1000 days of age in ad libitum fed and dietary restricted rats. Exp Gerontol 16:431-444
13. Phelan JP, Austad SN (1989) Natural selection, dietary restriction, and extended longevity. Growth Dev Aging 53:4-6
14. Phelan JP, Rose MR (2005) Why dietary restriction substantially increases longevity in animal models but won't in humans. Aging Res Rev 4:339-350
15. Pletcher SD, Libert S, Skorupa D (2005) Flies and their golden apples: the effect of dietary restriction on Drosophila aging and age-dependent gene expression. Ageing Res Rev 4:451-480
16. Rauser CL, Mueller LD, Rose MR (2004) Dietary restriction in Drosophila. Science (Letters) 303:1610-1611
17. Rose MR (1991) Evolutionary biology of aging. Oxford University Press, UK
18. Rose MR, Passananti HK, Matos M (2004) Methuselah flies: A case study in the evolution of aging. World Scientific Publishing, Singapore
19. Rose MR, Vu LN, Park SU, Graves JL (1992) Selection on stress resistance increases longevity in Drosophila melanogaster. Exp Gerontol 27:241-250
20. Service PM, Hutchinson EW, MacKinley MD, Rose MR (1985) Resistance to environmental stress in Drosophila melanogaster selected for postponed senescence. Physiol Zool 58:380-389
21. Stearns SC (1992) The evolution of life histories. Oxford University Press, UK
22. Tatar M, Kopelman A, Tu MP, Yin CM, Garofalo RS (2001) Mutant in Drosophila insulin receptor homologue extend lifespan and impair neuroendocrine function. Science 292:107-110
23. Williams GC (1957) Pleiotropy, natural selection, and the evolution of senescence. Evolution 11:398-411
24. Williams GC (1966) Natural selection, the cost of reproduction, and a refinement of Lack's principle. Am Nat 100:687-690