Alcohol withdrawal pharmacotherapy for inpatients with medical comorbidity

Journal of Addictive Diseases

Volumn 25, Issue 2, 2006, Pages 17-24

  Weaver, Michael F ^a,b   Hoffman, Heather J ^a   Johnson, Robert E ^a   Mauck, Kimberly ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b NONE   (United States)

Author keywords

Alcohol; Alcohol dependence; Alcohol withdrawal; Benzodiazepine; CIWA Ar; Clinical trial; Inpatient detoxification; Pharmacotherapy; Symptom triggered dosing

Indexed keywords

BENZODIAZEPINE; LORAZEPAM;

ADULT; AGED; ALCOHOL WITHDRAWAL; ALCOHOLISM; ARTICLE; CLINICAL TRIAL; COMORBIDITY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE REGIMEN; FEMALE; HOSPITAL PATIENT; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; NURSE; RATING SCALE; SCORING SYSTEM; THERAPEUTIC ERROR; WARD;

EID: 33746611551     PISSN: 10550887     EISSN: 15450848     Source Type: Journal    
DOI: 10.1300/J069v25n02_03     Document Type: Article

References (17)

1. Cross GM, Hennessey PT. Principles and practice of detoxification. Primary Care. 1993;20:81-93.
2. Moore RD, Bone LR, Geller LR, Mamon JA, Stokes EJ, Levine DM. Prevalence, detection, and treatment of alcoholism in hospitalized patients. JAMA. 1989;261:403-7.
3. Langenbucher J. Rx for health care costs: resolving addictions in the general medical setting. Alcohol Clin Exp Res. 1994;18:1033-6.
4. Wartenberg AA, Nirenberg TD, Liepman MR, Silvia LY, Begin AM, Monti PM. Detoxification of alcoholics: improving care by symptom-triggered sedation. Alcohol Clin Exp Res. 1990;14:71-5.
5. Sellers EM, Naranjo CA, Harrison M, et al. Diazepam loading: simplified treatment of alcohol withdrawal. Clin Pharmacol Ther 1983;34:822-6.
6. Hill A, Williams D. Hazards associated with the use of benzodiazepines in alcohol detoxification. J Substance Abuse Treat 1993;10:449-51.
7. Harman AW, Frewin DB, Priestly BG, Alexander CB. Impairment of hepatic drug metabolism in alcoholics. Br J Clin Pharmacol 1979;7:45-8.
8. Saitz R, Mayo-Smith MF, Roberts MS, Redmond HA, Bernard DR, Calkins DR. Individualized treatment for alcohol withdrawal: a randomized double-blind controlled trial. JAMA 1994;272(7):519-23.
9. Daeppen J-B, Gache P, Landry U, Sekera E, Schweizer V, Gloor S, et al. Symptom-triggered vs. FS doses of benzodiazepine for alcohol withdrawal a randomized treatment trial. Arch Intern Med 2002; 162: 1117-21.
10. Jaeger TM, Lohr RH, Pankratz VS. Symptomtriggered therapy of alcohol withdrawal syndrome in medical inpatients. Mayo Clin Proc 2001;76:695-701.
11. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington, DC: American Psychiatric Association; 1994.
12. Coogle CL, Osgood NJ, Parham IA. Follow-up to the statewide model detection and prevention program for geriatric alcoholism and alcohol abuse. Community Ment Health J. 2001;37:381-91.
13. Sullivan JT, Sykora K, Schneiderman J, Naranjo CA, Sellers EM. Assessment of alcohol withdrawal: the revised clinical institute withdrawal assessment for alcohol scale (CIWA-Ar). British Journal of Addiction. 1989;84:1353-7.
14. Sullivan JT, Swift RM, Lewis DC. Benzodiazepine requirements during alcohol withdrawal syndrome: clinical implications of using a standardized withdrawal scale. J Clin Psychopharmacol. 1991;11:291-5.
15. Stuppaeck CH, Pycha R, Miller C, Whitworth AB, Oberbauer H, Fleischhacker WW. Carbamazepine versus oxazepam in the treatment of alcohol withdrawal: a double-blind study. Alcohol Alcohol. 1992; 27:153-8.
16. Foy A, March S, Drinkwater V. Use of an objective clinical scale in the assessment and management of alcohol withdrawal in a large general hospital. Alcohol Clin Exp Res 1988;12:360-4.
17. Kessler RC, McGonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S, et al. Lifetime and 12-month prevalence of DSM IIIR psychiatric disorders in the United States. Arch Gen Psychiatry 1994;51:8-19.