Minimizing perioperative blood loss and transfusions in children

Canadian Journal of Anesthesia

Volumn 53, Issue 2, 2006, Pages

  Guay, Joanne ^a   de Moerloose, Philippe ^b   Lasne, Dominique ^c  

^a MAISONNEUVE ROSEMONT HOSPITAL   (Canada)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOCAPROIC ACID; APROTININ; BLOOD CLOTTING FACTOR 8 CRYOPRECIPITATE; DESMOPRESSIN; ERYTHROPOIETIN; FRESH FROZEN PLASMA; PLASMA SUBSTITUTE; RECOMBINANT BLOOD CLOTTING FACTOR 7A; TRANEXAMIC ACID;

AGE DISTRIBUTION; ANAPHYLAXIS; BLEEDING TENDENCY; BLOOD AUTOTRANSFUSION; BLOOD TRANSFUSION; BLOOD VOLUME; CHILD; CLINICAL TRIAL; COLLOID; CRYSTALLOID; CYANOTIC HEART DISEASE; DISEASE CLASSIFICATION; DRUG BLOOD LEVEL; DRUG COST; DRUG EFFICACY; DRUG SAFETY; ERYTHROCYTE TRANSFUSION; HEART SURGERY; HEMODILUTION; HUMAN; HYPERKALEMIA; HYPOCALCEMIA; IDIOPATHIC DISEASE; INTOXICATION; LIVER TRANSPLANTATION; META ANALYSIS; OXYGENATION; PATHOPHYSIOLOGY; PEDIATRIC SURGERY; PERIOPERATIVE PERIOD; PRIORITY JOURNAL; REOPERATION; REVIEW; RISK REDUCTION; SCOLIOSIS; SURGICAL RISK; SURGICAL TECHNIQUE; SYSTEMATIC REVIEW; THROMBOCYTE TRANSFUSION;

EID: 33746601314     PISSN: 0832610X     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03022253     Document Type: Review

References (74)

1. Guay J, Rivard GE. Mediastinal bleeding after cardiopulmonary bypass in pediatric patients. Ann Thorac Surg 1996; 62: 1955-60.
2. Kuhle S, Male C, Mitchell L. Developmental hemostasis: pro- and anticoagulant systems during childhood. Semin Thromb Hemost 2003; 29: 329-37.
3. Hezard N, Potron G, Schlegel N, Amory C, Leroux B, Nguyen P. Unexpected persistence of platelet hyporeactivity beyond the neonatal period: a flow cytometric study in neonates, infants and older children. Thromb Haemost 2003; 90: 116-23.
4. Miller BE, Bailey JM, Mancuso TJ, et al. Functional maturity of the coagulation system in children: an evaluation using thromboelastography. Anesth Analg 1997; 84: 745-8.
5. Williams GD, Bratton SL, Riley EC, Ramamoorthy C. Association between age and blood loss in children undergoing open heart operations. Ann Thorac Surg 1998; 66: 870-5.
6. Vieira A, Berry L, Ofosu F, Andrew M. Heparin sensitivity and resistance in the neonate: an explanation. Thromb Res 1991; 63: 85-98.
7. Chan AK, Berry LR, Monayle PT, Andrew M. Decreased concentrations of heparinoids are required to inhibit thrombin generation in plasma from newborns and children compared to plasma from adults due to reduced thrombin potential. Thromb Haemost 2002; 87: 606-13.
8. Monagle P, Michelson AD, Bovill E, Andrew M. Antithrombotic therapy in children. Chest 2001; 119: 344S-70.
9. Patel RI, DeWitt L, Hannallah RS. Preoperative laboratory testing in children undergoing elective surgery: analysis of current practice. J Clin Anesth 1997; 9: 569-75.
10. Leclerc J, Sorba F, Mrugalski P, Vallet B. Preoperative assessment of hemostasis in private clinics in Nord-Pas-de-Calais. Ann Fr Anesth Reanim, 2001; 20: 699-704.
11. Windfuhr JP, Chen YS. Incidence of post-tonsillectomy hemorrhage in children and adults: a study of 4,848 patients. Ear Nose Throat J 2002; 81: 626-8.
12. Liu JH, Anderson KE, Willging JP, et al. Posttonsillectomy hemorrhage: what is it and what should be recorded? Arch Otolaryngol Head Neck Surg 2001; 127: 1271-5.
13. Burk CD, Miller L, Handler SD, Cohen AR. Preoperative history and coagulation screening in children undergoing tonsillectomy. Pediatrics 1992; 89: 691-5.
14. Gabriel P, Mazoit X, Ecoffey C. Relationship between clinical history, coagulation tests, and perioperative bleeding during tonsillectomies in pediatrics. Clin Anesth 2000; 12: 288-91.
15. Sandoval C, Garcia C, Visintainer P, Ozkaynak MF, Jayabose S. The usefulness of preoperative screening for bleeding disorders. Clin Pediatr 2003; 42: 247-50.
16. Biron C, Mahieu B, Rochette A, et al. Preoperative screening for von Willebrand disease type 1: low yield and limited ability to predict bleeding. J Lab Clin Med 1999; 134: 605-9.
17. Cariappa R, Wilhite TR, Parvin CA, Luchtman-Jones L. Comparison of PFA-100 and bleeding time testing in pediatric patients with suspected hemorrhagic problems. J Pediatr Hematol Oncol 2003; 25: 474-9.
18. Nowatzke WL, Landt M, Smith C, Wilhite T, Canter C, Luchtman-Jones L. Whole blood international normalization ratio measurements in children using near-patient monitors. J Pediatr Hematol Oncol 2003; 25: 33-7.
19. Williams GD, Bratton SI, Ramamoorthy C. Factors associated with blood loss and blood product transfusions: a multivariate analysis in children after open-heart surgery. Anesth Analg 1999; 89: 57-64.
20. Ozier YM, Le Cam B, Chatellier G, et al. Intraoperative blood loss in pediatric liver transplantation: analysis of preoperative risk factors. Anesth Analg 1995; 81: 1142-7.
21. Horlocker TT, Nuttall GA, Dekutoski MB, Bryant SC. The accuracy of coagulation tests during spinal fusion and instrumentation. Anesth Analg 2001; 93: 33-8.
22. Roux CL, Lejus C, Surbleb M, et al. Is haemostasis biological screening always useful before performing a neuraxial blockade in children? Paediatr Anaesth 2002; 12: 118-23.
23. Guay J, Haig M, Lortie L, Guertin MC, Poitras B. Predicting blood loss in surgery for idiopathic scoliosis. Can J Anaesth 1994; 41: 775-81.
24. Meert K-L, Kannan S, Mooney JF. Predictors of red cell transfusion in children and adolescents undergoing spinal fusion surgery. Spine 2002; 27: 2137-42.
25. Meyer P, Renier D, Arnaud E, et al. Blood loss during repair of craniosynostosis. Br J Anaesth 1993; 71: 854-7.
26. Moenning JE, Bussard DA, Lapp TH, Garrison BT. Average blood loss and the risk of requiring perioperative blood transfusion in 506 orthognathic surgical procedures. J Oral Maxillofac Surg 1995; 53: 880-3.
27. Miller BE, Mochizuki T, Levy JH, et al. Predicting and treating coagulopathies after cardiopulmonary bypass in children. Anesth Analg 1997; 85: 1196-202.
28. Manno CS, Hedberg KW, Kim HC, et al. Comparison of the hemostatic effects of fresh whole blood, stored whole blood, and components after open heart surgery in children. Blood 1991; 77: 930-6.
29. Seear MD, Wadsworth LD, Rogers PC, Sheps S, Ashmore PG. The effect of desmopressin acetate (DDAVP) on postoperative blood loss after cardiac operations in children. J Thorac Cardiovasc Surg 1989; 98: 217-9.
30. Williams GD, Bratton SL, Riley EC, Ramamoorthy C. Coagulation tests during cardiopulmonary bypass correlate with blood loss in children undergoing cardiac surgery. J Cardiothorac Vasc Anesth 1999; 13: 398-404.
31. Carlier M, Van Obbergh LJ, Veyckemans F, et al. Hemostasis in children undergoing liver transplantation. Semin Thromb Hemost 1993; 19: 218-22.
32. Ryckman F, Fisher R, Pedersen S, et al. Improved survival in biliary atresia patients in the present era of liver transplantation. J Pediatr Surg 1993; 28: 382-5.
33. Superina RA, Pearl RH, Roberts EA, et al. Liver transplantation in children: the initial Toronto experience. J Pediatr Surg 1989; 24: 1013-9.
34. Lichtor JL, Emond J, Chung MR, Thistlethwaite JR, Broelsch CE. Pediatric orthotopic liver transplantation: multifactorial predictions of blood loss. Anesthesiology 1988; 68: 607-11.
35. Belani KG, Batra YK, Naasz M, Gillingham K, Payne WD. Infants are a higher intraoperative risk group for orthotopic liver transplantation. Transplant Proc 1994; 26: 196-7.
36. Bilik R, Greig P, Langer B, Superina RA. Survival after reduced-size liver transplantation is dependent on pretransplant status. J Pediatr Surg 1993; 28: 1307-11.
37. Fearon JA, Weinthal J. The use of recombinant erythropoietin in the reduction of blood transfusion rates in craniosynostosis repair in infants and children. Plast Reconstr Surg 2002; 109: 2190-6.
38. Vitale MG, Stazzone EJ, Gelijns AC, Moskowitz AJ, Roye DP Jr. The effectiveness of preoperative erythropoietin in averting allogenic blood transfusion among children undergoing scoliosis surgery. J Pediatr Orthop B 1998; 7: 203-9.
39. Murray DJ, Forbes RB, Titone MB, Weinstein SL. Transfusion management in pediatric and adolescent scoliosis surgery. Efficacy of autologous blood. Spine 1997; 22: 2735-40.
40. Hans P, Collin V, Bonhomme V, Damas F, Born JD, Lamy M. Evaluation of acute normovolemic hemodilution for surgical repair of craniosynostosis. J Neurosurg Anesthesiol 2000; 12: 33-6.
41. Copley LA, Richards BS, Safavi FZ, Newton PO. Hemodilution as a method to reduce transfusion requirements in adolescent spine fusion surgery. Spine 1999; 24: 219-22.
42. Siller TA, Dickson JH, Erwin WD. Efficacy and cost considerations of intraoperative autologous transfusion in spinal fusion for idiopathic scoliosis with predeposited blood. Spine 1996, 21: 848-52.
43. Guay J, Reinberg C, Poitras B, et al. A trial of desmopressin to reduce blood loss in patients undergoing spinal fusion for idiopathic scoliosis. Anesth Analg 1992; 75: 405-10.
44. Theroux MC, Corddry DH, Tietz AE, Miller F, Peoples JD, Kettrick RG. A study of desmopressin and blood loss during spinal fusion for neuromuscular scoliosis: a randomized, controlled, double-blinded study. Anesthesiology 1997; 87: 260-7.
45. Letts M, Pang E, D'Astous J, et al. The influence of desmopressin on blood loss during spinal fusion surgery in neuromuscular patients. Spine 1998; 23: 475-8.
46. Florentino-Pineda I, Blakemore LC, Thompson GH, Poe-Kochert C, Adler P, Tripi P. The Effect of epsilon-aminocaproic acid on perioperative blood loss in patients with idiopathic scoliosis undergoing posterior spinal fusion: a preliminary prospective study. Spine 2001; 26: 1147-51.
47. Neilipovitz DT, Murto K, Hall L, Barrowman NJ, Splinter WM. A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery. Anesth Analg 2001; 93: 82-7.
48. Sethna NF, Zurakowski D, Brustowicz RM, Bacsik J, Sullivan LJ, Shapiro F. Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery. Anesthesiology 2005; 102: 727-32.
49. Cole JW, Murray DJ, Snider RJ, Bassett GS, Bridwell KH, Lenke LG. Aprotinin reduces blood loss during spinal surgery in children. Spine 2003; 28: 2482-5.
50. Khoshhal K, Mukhtar I, Clark P, Jarvis J, Letts M, Splinter W. Efficacy of aprotinin in reducing blood loss in spinal fusion for idiopathic scohosis. J Pediatr Orthop 2003; 23: 661-4.
51. Rentoul TM, Harrison VL, Shun A. The effect of aprotinin on transfusion requirements in pediatric orthotopic liver transplantation. Pediatr Transplant 2003; 7: 142-8.
52. Simpson MB, Georgopoulos G, Eilert RE. Intraoperative blood salvage in children and young adults undergoing spinal surgery with predeposited autologous blood: efficacy and cost effectiveness. J Pediatr Orthop 1993; 13: 777-80.
53. Hishon ML, Ryan A, Lithgow P, Butt W. An evaluation of changes in composition and contamination of salvaged blood from the cardiopulmonary bypass circuit of pediatric patients. Heart Lung 1995; 24: 307-11.
54. Tobias JD. Synthetic factor VIIa to treat dilutional coagulopathy during posterior spinal fusion in two children. Anesthesiology 2002; 96: 1522-5.
55. Sonzogni V, Crupi G, Poma R, et al. Erythropoietin therapy and preoperative autologous blood donation in children undergoing open heart surgery Br J Anaesth 2001; 87: 429-34.
56. Reynolds LM, Nicolson SC, Jobes DR, et al. Desmopressin does not decrease bleeding after cardiac operation in young children. J Thorac Cardiovasc Surg 1993; 106: 954-8.
57. McClure PD, Izsak J. The use of epsilon-aminocaproic acid to reduce bleeding during cardiac bypass in children with congenital heart disease. Anesthesiology 1974; 40: 604-8.
58. Zonis Z, Seear M, Reichert C, Sett S, Allen C. The effect of preoperative tranexamic acid on blood loss after cardiac operations in children. J Thorac Cardiovasc Surg 1996; 111: 982-7.
59. Reid RW, Zimmerman AA, Laussen PC, Mayer JE, Gorlin JB, Burrows FA. The efficacy of tranexamic acid versus placebo in decreasing blood loss in pediatric patients undergoing repeat cardiac surgery. Anesth Analg 1997; 84: 990-6.
60. D'Errico CC, Shayevitz JR, Martindale SJ, Mosca RS, Bove EL. The efficacy and cost of aprotinin in children undergoing reoperative open heart surgery. Anesth Analg 1996; 83: 1193-9.
61. Guay J, Hardy JF. Association between age and blood loss in children undergoing open heart operations-Invited commentary. Ann Thorac Surg 1998; 66: 870-6.
62. Hiramatsu T, Okamura T, Imai Y, et al. Effects of autologous platelet concentrate reinfusion after open heart surgery in patients with congenital heart disease. Ann Thorac Surg 2002; 73: 1282-5.
63. Oliver WC Jr, Beynen FM, Nuttall GA, et al. Blood loss in infants and children for open heart operations: albumin 5% versus fresh-frozen plasma in the prime. Ann Thorac Surg 2003; 75: 1506-12.
64. Guay J, Ruest P, Lortie L. Cardiopulmonary bypass induces significant platelets activation in children undergoing open-heart surgery. Eur J Anaesthesiol 2004; 21: 953-6.
65. Mössinger H, Dietrich W, Braun SL, Jochum M, Meisner H, Richter JA. High-dose aprotinin reduces activation of hemostasis, allogenic blood requirement, and duration of postoperative ventilation in pediatric cardiac surgery. Ann Thorac Surg 2003; 75: 430-7.
66. Guay J, Lortie L. An evaluation of pediatric in-hospital advanced life support interventions using the pediatric Utstein guidelines: a review of 203 cardiorespiratory arrests. Can J Anesth 2004; 51: 373-8.
67. Roseff SD, Luban NL, Manno CS. Guidelines for assessing appropriateness of pediatric transfusion. Transfusion 2002; 42: 1398-413.
68. Voak D, Cann R, Finney RD, et al. Guidelines for administration of blood products: transfusion of infants and neonates. British Committee for Standards in Haematology Blood Transfusion Task Force. Transfus Med 1994; 4: 63-9.
69. Guidelines for red blood cell and plasma transfusion for adult and children. Report of the Expert Working Group. Can Med Assoc J 1997; 156 (Suppl 11): 1-24.
70. Canadian Paediatric Society. Red blood cell transfusions in newborn infants: revised guidelines. Paediatr Child Health 2002; 7: 553-8.
71. Borland LM, Roule M. The relation of preoperative coagulation function and diagnosis to blood usage in pediatric liver transplantation. Transplant Proc 1988; XX(Suppl 1): 533-5.
72. Kern FH, Morana NJ, Sears JJ, Hickey PR. Coagulation defects in neonates during cardiopulmonary bypass. Ann Thorac Surg 1992; 54: 541-6.
73. Brutocao D, Bratton SL, Thomas JR, Schrader PF, Coles PG, Lynn AM. Comparison of hetastarch with albumin for postoperative volume expansion in children after cardiopulmonary bypass. J Cardiothorac Vasc Anesth 1996; 10: 348-51.
74. Brown KA, Bissonnette B, McIntyre B. Hyperkalaemia during rapid blood transfusion and hypovolaemic cardiac arrest in children. Can J Anaesth 1990; 37: 747-54.