Functionally diverging molecular quasi-species evolve by crossing two enzymes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 29, 2006, Pages 10866-10870

  Emrén, Lars O ^a   Kurtovic, Sanela ^a   Runarsdottir, Arna ^a   Larsson, Anna Karin ^a   Mannenvik, Bengt ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Directed evolution; DNA shuffling; Glutathione transferase; Library; Multivariate analysis

Indexed keywords

DNA; ENZYME; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE M2; MUTANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DIRECTED MOLECULAR EVOLUTION; DNA RECOMBINATION; DNA SHUFFLING; ENZYME ACTIVITY; ENZYME SPECIFICITY; MOLECULAR EVOLUTION; NONHUMAN; PHENOTYPE; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; SPECIES DIFFERENTIATION;

EVOLUTION, MOLECULAR; GLUTATHIONE TRANSFERASE; HUMANS; ISOENZYMES; MOLECULAR STRUCTURE; MUTANT CHIMERIC PROTEINS; MUTATION; SUBSTRATE SPECIFICITY; VARIATION (GENETICS);

EID: 33746592452     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0604030103     Document Type: Article

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