A novel nucleocytoplasmic shuttling sequence of DAZAP1, a testis-abundant RNA-binding protein

RNA

Volumn 12, Issue 8, 2006, Pages 1486-1493

  Lin, Yi Tzu ^a   Yen, Pauline H ^a  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

Author keywords

DAZAP1; Nucleocytoplasmic shuttling; RNA binding protein

Indexed keywords

AMINO ACID; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN C1; NUCLEOTIDYLTRANSFERASE INHIBITOR; PROTEIN DAZAP1; RED FLUORESCENT PROTEIN; RNA BINDING PROTEIN; RNA POLYMERASE 2 INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HETEROKARYON; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; MUTAGENESIS; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN TRANSPORT; RNA TRANSCRIPTION; SEQUENCE HOMOLOGY; SOMATIC CELL; TESTIS;

3T3 CELLS; ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; CONSERVED SEQUENCE; COS CELLS; CYTOPLASM; DACTINOMYCIN; HELA CELLS; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP A-B; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP C; HUMANS; MALE; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NUCLEAR LOCALIZATION SIGNALS; RECOMBINANT FUSION PROTEINS; RNA-BINDING PROTEINS; TESTIS; TRANSCRIPTION, GENETIC;

EID: 33746565898     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.42206     Document Type: Article

References (36)

1. Akindahunsi, A.A., Bandiera, A., and Manzini, G. 2005. Vertebrate 2xRBD hnRNP proteins: A comparative analysis of genome, mRNA and protein sequences. Comput. Biol. Chem. 29: 13-23.
2. Beetz, C., Brodhun, M., Moutzouris, K., Kiehntopf, M., Berndt, A., Lehnert, D., Deufel, T., Bastmeyer, M., and Schickel, J. 2004. Identification of nuclear localisation sequences in spastin (SPG4) using a novel Tetra-GFP reporter system. Biochem. Biophys. Res. Commun. 318: 1079-1084.
3. Collier, B., Gorgoni, B., Loveridge, C., Cooke, H.J., and Gray, N.K. 2005. The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells. EMBO J. 24: 2656-2666.
4. Dai, T., Vera, Y., Salido, E.C., and Yen, P.H. 2001. Characterization of the mouse Dazap1 gene encoding an RNA-binding protein that interacts with infertility factors DAZ and DAZL. BMC Genomics 2: 6.
5. Dreyfuss, G., Matunis, M.J., Pinol-Roma, S., and Burd, C.G. 1993. hnRNP proteins and the biogenesis of mRNA. Annu. Rev. Biochem. 62: 289-321.
6. Fan, X.C. and Steitz, J.A. 1998. HNS, a nuclear-cytoplasmic shuttling sequence in HuR. Proc. Natl. Acad. Sci. 95: 15293-15298.
7. Fenaroli, A., Vujanac, M., De Cesare, D., and Zimarino, V. 2004. A small-scale survey identifies selective and quantitative nucleocytoplasmic shuttling of a subset of CREM transcription factors. Exp. Cell Res. 299: 209-226.
8. Fox, M., Urano, J., and Reijo Pera, R.A. 2005. Identification and characterization of RNA sequences to which human PUMILIO-2 (PUM2) and deleted in Azoospermia-like (DAZL) bind. Genomics 85: 92-105.
9. Hogarth, C., Itman, C., Jans, D.A., and Loveland, K.L. 2005. Regulated nucleocytoplasmic transport in spermatogenesis: A driver of cellular differentiation? Bioessays 27: 1011-1025.
10. Hori, T., Taguchi, Y., Uesugi, S., and Kurihara, Y. 2005. The RNA ligands for mouse proline-rich RNA-binding protein (mouse Prrp) contain two consensus sequences in separate loop structure. Nucleic Acids Res. 33: 190-200.
11. Jiao, X., Trifillis, P., and Kiledjian, M. 2002. Identification of target messenger RNA substrates for the murine deleted in azoospermia-like RNA-binding protein. Biol. Reprod. 66: 475-485.
12. Kamma, H., Portman, D.S., and Dreyfuss, G. 1995. Cell type-specific expression of hnRNP proteins. Exp. Cell Res. 221: 187-196.
13. Kerr, J.B. and de Kretser, D.M. 1974. Proceedings: The role of the Sertoli cell in phagocytosis of the residual bodies of spermatids. J. Reprod. Fertil. 36: 439-440.
14. Kimmins, S., Kotaja, N., Davidson, I., and Sassone-Corsi, P. 2004. Testis-specific transcription mechanisms promoting male germ-cell differentiation. Reproduction 128: 5-12.
15. Kurihara, Y., Watanabe, H., Kawaguchi, A., Hori, T., Mishiro, K., Ono, M., Sawada, H., and Uesugi, S. 2004. Dynamic changes in intranuclear and subcellular localizations of mouse Prrp/DAZAP1 during spermatogenesis: The necessity of the C-terminal proline-rich region for nuclear import and localization. Arch. Histol. Cytol. 67: 325-333.
16. Lai, M.C., Kuo, H.W., Chang, W.C., and Tarn, W.Y. 2003. A novel splicing regulator shares a nuclear import pathway with SR proteins. EMBO J. 22: 1359-1369.
17. Matz, M.V., Fradkov, A.F., Labas, Y.A., Savitsky, A.P., Zaraisky, A.G., Markelov, M.L., and Lukyanov, S.A. 1999. Fluorescent proteins from nonbioluminescent Anthozoa species. Nat. Biotechnol. 17: 969-973.
18. Michael, W.M., Choi, M., and Dreyfuss, G. 1995. A nuclear export signal in hnRNP A1: A signal-mediated, temperature-dependent nuclear protein export pathway. Cell 83: 415-422.
19. Michael, W.M., Eder, P.S., and Dreyfuss, G. 1997. The K nuclear shuttling domain: A novel signal for nuclear import and nuclear export in the hnRNP K protein. EMBO J. 16: 3587-3598.
20. Nakielny, S. and Dreyfuss, G. 1999. Transport of proteins and RNAs in and out of the nucleus. Cell 99: 677-690.
21. Pan, H.A., Lin, Y.S., Lee, K.H., Huang, J.R., Lin, Y.H., and Kuo, P.L. 2005. Expression patterns of the DAZ-associated protein DAZAP1 in rat and human ovaries. Fertil. Steril. 84 (Suppl. 2): 1089-1094.
22. Pinol-Roma, S. and Dreyfuss, G. 1991. Transcription-dependent and transcription-independent nuclear transport of hnRNP proteins. Science 253: 312-314.
23. _. 1992. Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm. Nature 355: 730-732.
24. Pinol-Roma, S., Choi, Y.D., Matunis, M.J., and Dreyfuss, G. 1988. Immunopurification of heterogeneous nuclear ribonucleoprotein particles reveals an assortment of RNA-binding proteins. Genes & Dev. 2: 215-227.
25. Poon, I.K. and Jans, D.A. 2005. Regulation of nuclear transport: Central role in development and transformation? Traffic 6: 173-186.
26. Reijo, R.A., Dorfman, D.M., Slee, R., Renshaw, A.A., Loughlin, K.R., Cooke, H., and Page, D.C. 2000. DAZ family proteins exist throughout male germ cell development and transit from nucleus to cytoplasm at meiosis in humans and mice. Biol. Reprod. 63: 1490-1496.
27. Reynolds, N., Collier, B., Maratou, K., Bingham, V., Speed, R.M., Taggart, M., Semple, C.A., Gray, N.K., and Cooke, H.J. 2005. Dazl binds in vivo to specific transcripts and can regulate the premeiotic translation of Mvh in germ cells. Hum. Mol. Genet. 14: 3899-3909.
28. Robbins, J., Dilworth, S.M., Laskey, R.A., and Dingwall, C. 1991. Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence. Cell 64: 615-623.
29. Ruggiu, M., Speed, R., Taggart, M., McKay, S.J., Kilanowski, F., Saunders, P., Dorin, J., and Cooke, H.J. 1997. The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis. Nature 389: 73-77.
30. Siomi, H. and Dreyfuss, G. 1995. A nuclear localization domain in the hnRNP A1 protein. J. Cell Biol. 129: 551-560.
31. Tsui, S., Dai, T., Roettger, S., Schempp, W., Salido, E.C., and Yen, P.H. 2000. Identification of two novel proteins that interact with germ-cell-specific RNA-binding proteins DAZ and DAZL1. Genomics 65: 266-273.
32. Venables, J.P., Ruggiu, M., and Cooke, H.J. 2001. The RNA-binding specificity of the mouse Dazl protein. Nucleic Acids Res. 29: 2479-2483.
33. Vera, Y., Dai, T., Hikim, A.P., Lue, Y., Salido, E.C., Swerdloff, R.S., and Yen, P.H. 2002. Deleted in azoospermia associated protein 1 shuttles between nucleus and cytoplasm during normal germ cell maturation. J. Androl. 23: 622-628.
34. Wood, L.D., Irvin, B.J., Nucifora, G., Luce, K.S., and Hiebert, S.W. 2003. Small ubiquitin-like modifier conjugation regulates nuclear export of TEL, a putative tumor suppressor. Proc. Natl. Acad. Sci. 100: 3257-3262.
35. Xu, C. and Henry, M.F. 2004. Nuclear export of hnRNP Hrp1p and nuclear export of hnRNP Npl3p are linked and influenced by the methylation state of Npl3p. Mol. Cell. Biol. 24: 10742-10756.
36. Zhao, W.M., Jiang, C., Kroll, T.T., and Huber, P.W. 2001. A proline-rich protein binds to the localization element of Xenopus Vg1 mRNA and to ligands involved in actin polymerization. EMBO J. 20: 2315-2325.