Interferon α 2b treatment for residual ocular surface squamous neoplasia unresponsive to excision, cryotherapy and mitomycin-C

Clinical and Experimental Ophthalmology

Volumn 34, Issue 4, 2006, Pages 375-377

  Nemet, Arie Y ^a   Sharma, Vidushi ^a   Benger, Ross ^a  

^a SYDNEY EYE HOSPITAL   (Australia)

Author keywords

Carcinoma in situ; Fluorouracil; Interferon type II; Mitomycin c

Indexed keywords

MITOMYCIN C; RECOMBINANT ALPHA2B INTERFERON;

ADULT; AGED; ARTICLE; CASE REPORT; CRYOTHERAPY; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG SAFETY; DRUG TREATMENT FAILURE; DRY EYE; EYE DISEASE; EYE SURGERY; EYE TUMOR; EYELID DISEASE; FEMALE; FOLLOW UP; HUMAN; LONG TERM CARE; MALE; OCULAR SURFACE SQUAMOUS NEOPLASIA; PUNCTATE KERATITIS; SYMPTOM; TERTIARY HEALTH CARE; TUMOR GROWTH; TUMOR RECURRENCE; UNSPECIFIED SIDE EFFECT;

AGED; AGED, 80 AND OVER; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; CARCINOMA IN SITU; CONJUNCTIVAL NEOPLASMS; CORNEAL DISEASES; CRYOTHERAPY; FEMALE; HUMANS; INTERFERON ALFA-2B; MALE; MIDDLE AGED; MITOMYCIN; NEOPLASM, RESIDUAL; TREATMENT FAILURE; TREATMENT OUTCOME;

EID: 33746537196     PISSN: 14426404     EISSN: 14429071     Source Type: Journal    
DOI: 10.1111/j.1442-9071.2006.01226.x     Document Type: Article

References (7)

1. Boehm MD, Huang AJ. Treatment of recurrent corneal and conjunctival intraepithelial neoplasia with topical interferon alfa 2b. Ophthalmology 2004; 111: 1755-61.
2. Maskin SL. Regression of limbal epithelial dysplasia with topical interferon. Arch Ophthalmol 1994; 112: 1145-6.
3. Vann RR, Karp CL. Perilesional and topical interferon alfa-2b for conjunctival and corneal neoplasia. Ophthalmology 1999; 106: 91-7.
4. Schechter BA, Schrier A, Nagler RS et al. Regression of presumed primary conjunctival and corneal intraepithelial neoplasia with topical interferon alpha-2b. Cornea 2002; 21: 6-11.
5. Frucht-Pery J, Rozenman Y, Pe'er J. Topical mitomycin-C for partially excised conjunctival squamous cell carcinoma. Ophthalmology 2002; 109: 548-52.
6. Detjen KM, Welzel M, Farwig K et al. Molecular mechanism of interferon alfa-mediated growth inhibition in human neuroendocrine tumor cells. Gastroenterology 2000; 118: 735-48.
7. Smith M, Trousdale MD, Rao NA, Robin JB. Lack of toxicity of a topical recombinant interferon alpha. Cornea 1989; 8: 58-61.