Mild tubular damage induces calcium oxalate crystalluria in a model of subtle hyperoxaluria: Evidence that a second hit is necessary for renal lithogenesis

Journal of the American Society of Nephrology

Volumn 17, Issue 8, 2006, Pages 2213-2219

  Gambaro, Giovanni ^a   Valente, Maria Luisa ^b   Zanetti, Edoardo ^b   Della Barbera, Mila ^b   Del Prete, Dorella ^b   D'Angelo, Angela ^b   Trevisan, Andrea ^b  

^a UNIVERSITY OF VERONA   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM OXALATE; ETHYLENE GLYCOL; HEXACHLOROBUTADIENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CRYSTALLURIA; DIET; ENVIRONMENTAL FACTOR; ENZYMURIA; HYPEROXALURIA; KIDNEY TUBULE DAMAGE; KIDNEY TUBULE EPITHELIUM; MALE; NEPHROLITHIASIS; NONHUMAN; NUTRITION; PRIORITY JOURNAL; PROTEINURIA; RAT; RAT STRAIN; STONE FORMATION; TRANSMISSION ELECTRON MICROSCOPY;

EID: 33746509130     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2005121282     Document Type: Article

References (31)

1. Goldfarb S: Dietary factors in the pathogenesis and prophylaxis of calcium nephrolithiasis. Kidney Int 34: 544-555, 1988
2. Borghi L, Meschi T, Amato F, Novarini A, Romanelli A, Cigala F: Hot occupation and nephrolithiasis. J Urol 150: 1757-1760, 1993
3. Gambaro G, Vezzoli G, Casari G, Rampoldi L, D'Angelo A, Borghi L: Genetics of hypercalciuria and calcium nephrolithiasis: From the rare monogenic to the common polygenic forms. Am J Kidney Dis 44: 963-986, 2004
4. Robertson WG, Heyburn PJ, Peacock M, Hanes FA, Swaminathan R: The effect of high animal protein intake on the risk of calcium stone-formation in the urinary tract. Clin Sci 57: 285-288, 1979
5. Robertson WG, Peacock M, Heyburn PJ, Hanes FA, Rutherford A, Clementson E, Swaminathan R, Clark PB: Should recurrent calcium oxalate stone formers become vegetarians? Br J Urol 51: 427-431, 1979
6. Kok DJ, Iestra JA, Doorenbos CJ, Papapoulos SE: The effects of dietary excesses in animal protein and in sodium on the composition and crystallization kinetics of calcium oxalate monohydrate in urines of healthy men. J Clin Endocrinol Metab 71: 861-867, 1990
7. Kok DJ, Khan SR: Calcium oxalate nephrolithiasis, a free or fixed particle disease. Kidney Int 46: 847-854, 1994
8. Lieske JC, Toback FG: Interaction of urinary crystals with renal epithelial cells in the pathogenesis of nephrolithiasis. Semin Nephrol 16: 458-473, 1996
9. Khan SR, Shevock PN, Hackett RL: Acute hyperoxaluria, renal injury and calcium oxalate urolithiasis. J Urol 147: 226-230, 1992
10. Khan SR, Byer KJ, Thamilselvan S, Hackett RL, McCormack WT, Benson NA, Vaughn KL, Erdos GW: Crystal-cell interaction and apoptosis in oxalate-associated injury of renal epithelial cells. J Am Soc Nephrol 10[Suppl 14]: S457-S463, 1999
11. Kumar S, Sigmon D, Miller T, Carpenter B, Khan S, Malhotra R, Schedi C, Menon M: A new model of nephrolithiasis involving tubular dysfunction/injury. J Urol 146: 1384-1389, 1991
12. Hackett RL, Shevock PN, Khan SR: Cell injury associated calcium oxalate crystalluria. J Urol 144: 1535-1538, 1990
13. Ishmael J, Pratt I, Lock EA: Necrosis of the part recta (S3 segment) of the rat kidney produced by hexachloro 1:3 butadiene. J Pathol 138: 99-113, 1982
14. Lerche D, van de Plassche E, Schwegler A, Balk F: Selecting chemical substances for the UN-ECE POP protocol. Chemosphere 47: 617-630, 2002
15. Goldbach RW, van Genderen H, Leeuwangh P: Hexachlorobutadiene residues in aquatic fauna from surface water fed by the river Rhine. Sci Total Environ 6: 31-40, 1976
16. Fattore E, Muller L, Davoli E, Castelli D, Benfenati E: Industrial pollutants in ground waters from northern Milan. Chemosphere 36: 2007-2017, 1998
17. Lee CL, Song HJ, Fang MD: Concentrations of chlorobenzenes, hexachlorobutadiene and heavy metals in surficial sediments of Kaohsiung coast, Taiwan. Chemosphere 41: 889-899, 2000
18. Karlsson N, Fangmark I, Haggqvist I, Karlsson B, Rittfeldt L, Marchner H: Mutagenicity testing of condensates of smoke from titanium dioxide/ hexachloroethane and zinc/hexachloroethane pyrotechnic mixtures. Mutat Res 260: 39-46, 1991
19. de Water R, Boeve ER, van Miert PP, Deng G, Cao LC, Stijnen T, de Bruijn WC, Schroder FH: Experimental nephrolithiasis in rats: The effect of ethylene glycol and vitamin D3 on the induction of renal calcium oxalate crystals. Scanning Microsc 10: 591-601, 1996
20. Pesce MA, Strande CS: A new micromethod for determination of protein in cerebrospinal fluid and urine. Clin Chem 19: 1265-1267, 1973
21. Baggio B, Gambaro G, Ossi E, Favaro S, Borsatti A: Increased urinary excretion of renal enzymes in idiopathic calcium oxalate nephrolithiasis. J Urol 129: 1161-1162, 1983
22. Trevisan A, Cristofori P, Fanelli G, Bicciato F, Stocco E: Glutamine transaminase K intranephron localization in rats determined by urinary excretion after treatment with segment-specific nephrotoxicants. Arch Toxicol 72: 531-535, 1998
23. Yamaguchi S, Wiessner JH, Hasegawa AT, Hung LY, Mandel GS, Mandel NS: Study of a rat model for calcium oxalate crystal formation without severe renal damage in selected conditions. Int J Urol 12: 290-298, 2005
24. Dekant W, Vamvakas S, Koob M, Kochling A, Kanhai W, Muller D, Henschler D: A mechanism of haloalkene-induced renal carcinogenesis. Environ Health Perspect 88: 107-110, 1990
25. Thamilselvan S, Byer KJ, Hackett RL, Khan SR: Free radical scavengers, catalase and superoxide dismutase provide protection from oxalate-associated injury to LLC-PK1 and MDCK cells. J Urol 164: 224-229, 2000
26. Maroni PD, Koul S, Chandhoke PS, Meacham RB, Koul HK: Oxalate toxicity in cultured mouse inner medullary collecting duct cells. J Urol 174: 757-760, 2005
27. Chien CT, Lee PH, Chen CF, Ma MC, Lai MK, Hsu SM: De novo demonstration and co-localization of free-radical production and apoptosis formation in rat kidney subjected to ischemia/reperfusion. J Am Soc Nephrol 12: 973-982, 2001
28. Bigelow MW, Wiessner JH, Kleinman JG, Mandel NS: Surface exposure of phosphatidylserine increases calcium oxalate crystal attachment to IMCD cells. Am J Physiol 272: F55-F62, 1997
29. Sarica K, Erbagci A, Yagci F, Bakir K, Erturhan S, Ucak R: Limitation of apoptotic changes in renal tubular cell injury induced by hyperoxaluria. Urol Res 32: 271-277, 2004
30. Khan SR: Animal models of kidney stone formation: An analysis. World J Urol 15: 236-243, 1997
31. Evan AP, Lingeman JE, Coe FL, Parks JH, Bledsoe SB, Shao Y, Sommer AJ, Paterson RF, Kuo RL, Grynpas M: Randall's plaque of patients with nephrolithiasis begins in basement membranes of thin loops of Henle. J Clin Invest 111: 607-616, 2003