The role of contrast-enhanced ultrasound on the diagnosis of small hepatocellular carcinoma (≤3 cm) in patients with cirrhosis

Hepatology Research

Volumn 35, Issue 4, 2006, Pages 281-288

  Chen, Min Hua ^a   Dai, Ying ^a   Yan, Kun ^a   Fan, Zhi Hui ^a   Yin, Shan Shan ^a   Yang, Wei ^a   Wu, Wei ^a   Wang, Yan Bin ^a   Li, Ji You ^a  

^a PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

Author keywords

Cirrhosis; Contrast agent; Hepatocellular carcinoma; Small lesion; Ultrasound

Indexed keywords

SONOVUE;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER PATIENT; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DIAGNOSTIC VALUE; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGING SYSTEM; INTERMETHOD COMPARISON; LIVER BIOPSY; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCHOOL CHILD; SCORING SYSTEM; TUMOR DIFFERENTIATION; TUMOR VOLUME; ULTRASOUND;

EID: 33746496262     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hepres.2006.04.013     Document Type: Article

References (28)

1. Zardi E.M., Uwechie V., Picardi A., and Costantino S. Liver focal lesions and hepatocellular carcinoma in cirrhotic patients: from screening to diagnosis. Clin Ter 152 (2001) 185-188
2. Gritzmann N. Small hepatocellular carcinomas in patients with liver cirrhosis: potentials and limitations of contrast-enhanced power Doppler sonography. Eur J Gastroenterol Hepatol 15 (2003) 881-883
3. Kim C.K., Lim J.H., and Lee W.J. Detection of hepatocellular carcinomas and dysplastic nodules in cirrhotic liver: accuracy of ultrasongraphy in transplant patients. J Ultrasound Med 20 (2001) 99-104
4. Feder le M.P. Use of radiologic techniques to screen for hepatocellular carcinoma. J Clin Gastroenterol 5 Suppl. 2 (2001) S92-S100
5. de Ledinghen V., Laharie D., Lecesne R., et al. Detection of nodules in liver cirrhosis: spiral computed tomography or magnetic resonance imaging? A prospective study of 88 nodules in 34 patients. Eur J Gastroenterol Hepatol 14 (2002) 159-165
6. Numata K., Tanaka K., Kiba T., et al. Contrast-enhanced, wide-band harmonic gray scale imaging of hepatocellular carcinoma: correlation with helical computed tomographic findings. J Ultrasound Med 20 (2001) 89-98
7. Bernatik T., Strobel D., Hahn E.G., and Becker D. Detection of liver metastases: comparison of contrast-enhanced wide-band harmonic imaging with conventional ultrasonography. J Ultrasound Med 20 (2001) 509-515
8. Isozaki T., Numata K., Kiba T., et al. Differential diagnosis of hepatic tumors by using contrast enhancement patterns at US. Radiology 229 (2003) 798-805
9. Furuse J., Nagase M., Ishii H., et al. Contrast enhancement patterns of hepatic tumours during the vascular phase using coded harmonic imaging and Levovist to differentiate hepatocellular carcinoma from other focal lesions. Br J Radiol 76 (2003) 385-392
10. Moriyasu F. Ultrasound contrast agents-newly developed agents and their clinical utility. Nippon Rinsho 56 (1998) 848-853
11. Leen E., Angerson W.J., Yarmenitis S., et al. Multi-centre clinical study evaluating the efficacy of SonoVue (BR1), a new ultrasound contrast agent in Doppler investigation of focal hepatic lesions. Eur J Radiol 41 (2002) 200-206
12. Quaia E., Calliada F., Bertolotto M., et al. Characterization of focal liver lesions with contrast-specific US modes and a sulfur hexafluoride-filled microbubble contrast agent: diagnostic performance and confidence. Radiology 232 (2004) 420-430
13. Harvey C.J., and Albrecht T. Ultrasound of focal liver lesions. Eur Radiol 11 (2001) 1578-1593
14. Chen M.H., Dai Y., Yan K., et al. Early diagnosis of small hepatocellular carcinoma in patients with cirrhosis using contrast-enhanced ultrasound. Chin J Ultrasonogr 14 (2005) 108-112
15. Sakamoto M., Hirohashi S., and Shimosato Y. Early stages of multistep hepatocarcinogenesis: adenomatous hyperplasia and early hepatocellular carcinoma. Hum Pathol 22 (1991) 172-178
16. Kutami R., Nakashima Y., Nakashima O., et al. Pathomorphologic study on the mechanism of fatty change in small hepatocellular carcinoma of humans. J Hepatol 33 (2000) 282-289
17. Wilson S.R., Burns P.N., Murdali D., et al. Harmonic hepatic US with microbubbles contrast agent: initial experience showing improved characterization of haemangioma, hepatocellular carcinoma and metastasis. Radiology 215 (2000) 147-157
18. Nicolau C., Catala V., and Bru C. Characterization of focal liver lesions with contrast-enhanced ultrasound. Eur Radiol 13 Suppl. 3 (2003) N70-N78
19. Matsui O., Kadoya M., Kameyama T., et al. Benign and malignant nodules in cirrhotic livers: distinction based on blood supply. Radiology 178 (1991) 493-497
20. Breedis C., and Young G. The blood supply of neoplasms in the liver. Am J Pathol 30 (1954) 969-977
21. Matsui O., Kadoya M., Kameyama T., et al. Benign and malignant nodules in cirrhotic livers: distinction based on blood supply. Radiology 178 (1991) 493-497
22. Kudo M. Imaging blood flow characteristics of hepatocellular carcinoma. Oncology 62 Suppl. 1 (2002) 48-56
23. Nicolau C., Catala V., Vilana R., et al. Evaluation of hepatocellular carcinoma using SonoVue, a second generation ultrasound contrast agent: correlation with cellular differentiation. Eur Radiol 14 (2004) 1092-1099
24. Grigioni W.F., D'Errico A., Mancini A.M., et al. Hepatocellular carcinoma: expression of basement membrane glycoproteins. An immunohistochemical approach. J Pathol 152 (1987) 325-332
25. Tateishi Y. Diagnosis of 26 small hepatocellular carcinoma using incremental dynamic computed tomography. Kurume Med J 44 (1997) 321-326
26. Karahan O.I., Yikilmaz A., Isin S., and Orhan S. Characterization of hepatocellular carcinomas with triphasic CT and correlation with histopathologic findings. Acta Radiol 44 (2003) 566-571
27. Tajima T., Honda H., Taguchi K., et al. Sequential hemodynamic change in epatocellular carcinoma and dysplastic nodules: CT angiography and pathologic correlation. AJR 178 (2002) 885-897
28. Yang S.H., Watanabe J., Nakashima O., and Kojiro M. Clinicopathologic study on clear cell hepatocellular carcinoma. Pathol Int 46 (1996) 503-509