Syntheses of metabolites of ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-(1,2,4-triazol-1-ylmethyl)quinoline-3-carboxylate (TAK-603)

Tetrahedron

Volumn 62, Issue 37, 2006, Pages 8707-8714

  Mizuno, Masahiro ^a   Yamashita, Makoto ^a   Sawai, Yasuhiro ^a   Nakamoto, Koji ^a   Goto, Mitsutaka ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

Friedel Crafts reaction; Kr hnke reaction; Metabolite; Methanesulfonyl group; Pyridazinoquinolinone; TAK 603

Indexed keywords

10 (3,4 DIMETHOXYPHENYL) 7,8 DIMETHOXY 2H PYRIDAZINO[4,5 B]QUINOLIN 1 ONE; 4 (3,4 DIMETHOXYPHENYL) 6,7 DIMETHOXY 2 (1,2,4 TRIAZOL 1 YLMETHYL) 3 QUINOLINECARBOXYLIC ACID ETHYL ESTER; DRUG METABOLITE; HYDRAZINE; PHENOL; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CYCLIZATION; DRUG SYNTHESIS; FRIEDEL CRAFTS REACTION; METABOLITE; PRIORITY JOURNAL;

EID: 33746494486     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2006.06.110     Document Type: Article

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