In vitro and in vivo studies on some toxic effects of the venom from Hemiscorpious lepturus scorpion

Toxicon

Volumn 48, Issue 1, 2006, Pages 93-103

  Pipelzadeh, Mohammad Hassan ^a   Dezfulian, Abdul Rahman ^a   Jalali, Mohammad Taha ^a   Mansouri, Abdul Karim ^a  

^a AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cytotoxcity; Haemolysis; Hemiscorpious lepturus; Heptotoxicity; Nephrotoxicity; Rat

Indexed keywords

ACETYLCHOLINE; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; AMYLASE; ASPARTATE AMINOTRANSFERASE; ATROPINE; SCORPION VENOM; TRYPAN BLUE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; AMYLASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BIOCHEMISTRY; BLOOD; BLOOD CELL COUNT; CELL CULTURE; CENTRIFUGATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE; FIBROBLAST; FIBROBLAST CULTURE; HEMISCORPIOUS LEPTURUS; HEMOLYSIS; HISTOLOGY; HUMAN; HUMAN CELL; ILEUM; INFLAMMATION; KIDNEY; LABORATORY; LETHAL DOSE; LIVER TOXICITY; LYSIS; MALE; MICROSCOPY; MUSCLE RELAXATION; NEPHRON; NEPHROTOXICITY; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEINURIA; RAT; SCORPION; SKIN; SKIN NECROSIS; STAINING; STATISTICAL SIGNIFICANCE; TOXICITY TESTING; URINALYSIS;

ACETYLCHOLINE; ANIMALS; FIBROBLASTS; HEMOLYSIS; ILEUM; KIDNEY; LIVER; MALE; RATS; RATS, WISTAR; SCORPION VENOMS; SKIN;

LEPTURUS; SCORPIONES;

EID: 33746476393     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2006.04.017     Document Type: Article

References (22)

1. Abbondonzo S.J., Gadi I., and Stewrt C.L. Derivation of embryonic stem cell lines. Meth. Enzymol. 225 (1993) 803-823
2. Chaim O.M., Sade Y.B., de Silveira R.B., Toma L., Kalapothakis E., Chaves-Olortegui C., Mangili O.C., Gremski W., von Dietrich C.P., Nader H.B., and Veiga S.S. Brown spider dermonecrotic toxin directly induced nephrotoxicity. Toxicol. Appl. Pharmacol. 211 1 (2006) 64-77
3. Dehesa-Davila M., and Possani L.D. Scorpionism and serotherapy in Mexico. Toxicon. 32 (1994) 1015-1081
4. Farzanpay R. Identification of Scorpions. first ed (1987), Tehran University Press p. 189 (in Persian)
5. Freire-Maia L., and Campos J.A. On the treatment of cardiovascular manifestations of scorpion envenomation. Toxicon. 25 (1987) 125-128
6. Fujii T., Kurata H., Takoka M., Fujisawa Y., Shokoji T., Nishiyama A., Abe Y., and Matsumura Y. The role of sympathetic nervous system in the pathogenesis of ischemic acute renal failure. Eur. J. Pharmacol. 481 (2003) 241-248
7. Futrell J. Loxoscelism. Am. J. Med. Sci. 304 (1992) 261-267
8. Gureon M., and Ovsyshcher I. Cardiovascular effects of scorpion venoms. In: Tu A. (Ed). Insect Poisons, Allergens, and other Invertebrate Venoms: Handbook of Natural Toxins vol. 2 (1984), Marcel Dekker, New York 639-649
9. Gureon M., and Yarom R. Cardiovascular manifestations of severe scorpion sting. Chest 57 (1970) 156-162
10. Gwee M.C.E., Cheah L.S., Gopalkrishnakone P., Wong P.T.H., Gong J.P., and Kini R.M. Studies on venom from the black scorpion Heteromertus longimanus and some other scorpion species. J. Toxicol.-Toxin Rev. 15 1 (1996) 37-57
11. Hassan F. Production of scorpion antivenom. In: Tu A.T. (Ed). Handbook of Toxins. Insects Poisons, Allergens and Other Invertebrate Venoms vol. 2 (1984), Marcel Dekker, New York 577-605
12. Kiernan J.A. Histological and Biochemical Methods: Theory and Practice. third ed (1999), Butterworth Heinmann, Oxford (pp. 154-155)
13. Murthy K.R.K., and Hase N.K. Scorpion envenoming and the role of insulin. Toxicon. 32 (1994) 1041-1044
14. 2+ induced hepatocyte cytotoxicity. Chem. Biol. Interact. 2000 6 (2000) 343-352
15. Prendini L. Phylogeny and classification of the superfamily Scorpionidea Latreille (Chelicerata, Scorpioes): an examplear approach. Cladistics 16 (1802) 1-78
16. Pringle G. Notes on the scorpions of Iraq. Bull. Endem. Dis. 3 (1960) 73-87
17. Radmanesh M. Clinical study of Hemiscorpion lepturus sting in Iran: a clinical study. J. Tropic. Med. Hyg. 93 (1990) 327-332
18. Radmanesh M. Cutaneous manifestations of the Hemiscorpion lepturus. Internat. J. Dermatol. 37 (1998) 500-507
19. Veiga S.S., Zanetti V.C., Franco C.R.C., Trindade E.S., Porcionatto M.A., Mangili O.C., Gremski W., Dietrich C.P., and Nader H.B. In vivo and in virto cytotoxicity of brown spider venom for blood vessel endothelial cells. Thromb. Res. 102 (2001) 229-237
20. Wallach J. Interpretation of Diagnostic Tests: A Synopsis of Laboratory Medicine. fifth ed (1992), Little Brown, Boston (pp. 560-563, 57-60)
21. Wong R.C., Hughes S.E., and Voorhees J.J. Spider bites. Arch. Dermatol. 12 1 (1987) 98-104
22. Woolf N. Cell, Tissue and Disease: The Basis of Pathology. third ed (2000), W. B. Saunders, Edinburgh (pp. 43-46)