PACAP stimulates the release of the secretogranin II-derived peptide EM66 from chromaffin cells

Annals of the New York Academy of Sciences

Volumn 1070, Issue , 2006, Pages 309-312

  Guillemot, Johann ^a   Ait Ali, Djida ^a   Turquier, Valerie ^a   Montero Hadjadje, Maite ^a   Fournier, Alain ^b   Vaudry, Hubert ^a   Anouar, Youssef ^a   Yon, Laurent ^a  

^a UNIVERSITÉ DE ROUEN   (France)

^b INRS INSTITUT ARMAND FRAPPIER   (Canada)

Author keywords

Bovine chromaffin cells; EM66; PACAP; Secretogranin II; Transduction pathways

Indexed keywords

CALCIUM CHANNEL L TYPE; CYCLIC AMP DEPENDENT PROTEIN KINASE; EM66 PEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; MITOGEN ACTIVATED PROTEIN KINASE; PEPTIDE; PROTEIN KINASE C; SECRETOGRANIN II; UNCLASSIFIED DRUG;

ADRENAL MEDULLA; ANIMAL CELL; CALCIUM TRANSPORT; CELL CULTURE; CELL STIMULATION; CHROMAFFIN CELL; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; DATA ANALYSIS; NEUROENDOCRINOLOGY; NONHUMAN; PROTEIN SECRETION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

BOS TAURUS;

EID: 33746468520     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1317.033     Document Type: Conference Paper

References (6)

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3. ANOUAR, Y., S. JEGOU, D. ALEXANDRE, et al. 1996. Molecular cloning of frog secretogranin II reveals the occurrence of several highly conserved potential regulatory peptides. FEBS Eett. 394: 295-299.
4. ANOUAR, Y., C. DESMOUCELLES, L. YON, et al. 1998. Identification of a novel secretogranin II-derived peptide [SgII(187-252)] in adult and fetal human adrenal glands using antibodies raised against the human recombinant peptide. J. Clin. Endocrinol. Metab. 83: 2944-2951.
5. MONTERO-HADJADJE, M., G. PELLETIER, L. YON, et al. 2003. Biochemical characterization and immunocytochemical localization of EM66, a novel peptide derived from secretogranin II, in the rat pituitary and adrenal glands. J. Histochem. Cytochem. 51: 1083-1095.
6. TURQUIER, V., L. YON, L. GRUMOLATO, et al. 2001. Pituitary adenylate cyclase-activating polypeptide stimulates secretoneurin release and secretogranin II gene transcription in bovine adrenochromaffin cells through multiple signaling pathways and increased binding of pre-existing activator protein-1-like transcription factors. Mol. Pharmacol. 60: 42-52.