Usefulness of acr expression for monitoring latent Mycobacterium tuberculosis bacilli in 'in vitro' and 'in vivo' experimental models

Scandinavian Journal of Immunology

Volumn 64, Issue 1, 2006, Pages 30-39

  Gordillo, S ^b   Guirado, E ^b   Gil, O ^b   Diaz J ^b   Amat, I ^b   Molinos, S ^b   Vilaplana, C ^b   Ausina, V ^b   Cardona, P J ^a  

^a HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CRYSTALLIN; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; ISONIAZID; LYMPHOTOXIN; MESSENGER RNA; RIBOSOME RNA; RIFAMPICIN; RNA; SIGMA FACTOR; SIGMA FACTOR A; SIGMA FACTOR B; SIGMA FACTOR E; SIGMA FACTOR F; SIGMA FACTOR G; SIGMA FACTOR H; SIGMA FACTOR M; STREPTOMYCIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; FLIA PROTEIN, BACTERIA; ICL PROTEIN, MYCOBACTERIUM; ISOCITRATE LYASE;

ACR GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL COUNT; BACTERIAL GROWTH; BACTERIUM CULTURE; COLONY FORMING UNIT; CONTROLLED STUDY; GENE; GENE EXPRESSION; IMMUNE DEFICIENCY; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATIENT MONITORING; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; TUBERCULOSIS; ANIMAL; DISEASE MODEL; FEMALE; GENE EXPRESSION REGULATION; GENETIC MARKER; GENETICS; GERMFREE ANIMAL; GROWTH, DEVELOPMENT AND AGING; MICROBIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALPHA-CRYSTALLINS; ANIMALS; BACTERIAL PROTEINS; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC MARKERS; ISOCITRATE LYASE; MICE; MYCOBACTERIUM TUBERCULOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGMA FACTOR; SPECIFIC PATHOGEN-FREE ORGANISMS; TUBERCULOSIS;

EID: 33746459046     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2006.01765.x     Document Type: Article

References (41)

1. American Thoracic Society. Targeted tuberculin testing and treatment of latent tuberculosis infection. Am J Respir Crit Care Med 2000;161:S221-47.
2. Hernandez-Pando R, Jeyanathan M, Mengistu G et al. Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection. Lancet 2000;356:2133-8.
3. Cole ST, Brosch R, Parkhill J et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 1998;393:537-44.
4. Rosenkrands I, King A, Weldingh K, Moniatte M, Moertz E, Andersen P. Towards the proteome of Mycobacterium tuberculosis. Electrophoresis 2000;21:3740-56.
5. Wayne LG, Sohaskey CD. Nonreplicating persistence of Mycobacterium tuberculosis. Annu Rev Microbiol 2001;55:139-63.
6. Wayne LG, Lin KY. Glyoxylate metabolism and adaptation of Mycobacterium tuberculosis to survival under anaerobic conditions. Infect Immun 1982;37:1042-9.
7. Balasubramanian MK, Wiegeshaus EH, Taylor BT, Smith DW. Pathogenesis of tuberculosis: pathway to apical localization. Tuberc Lung Dis 1994;75:168-78.
8. Opie EL, Aronson JD. Tubercle bacilli in latent tuberculous lesions and in lung tissue without tuberculous lesions. Arch Pathol Laboratory Med 1927;4:1-21.
9. Garbe TR, Hibler NS, Deretic V. Response to reactive nitrogen intermediates in Mycobacterium tuberculosis: induction of the 16-kilodalton a-crystallin homolog by exposure to nitric oxide donors. Infect Immun 1999;67:460-5.
10. Mason CA, Egli T. Dynamics of microbial growth in the decelerating and stationary phase of batch culture. In: Kjelleberg, S, ed. Starvation in Bacteria. New York: Plenum Press, 1993: 81-102.
11. Michele TM, Chiew K, Bishai WR. Exposure to antibiotics induces expression of the Mycobacterium tuberculosis sigF gene: implications for chemotherapy against mycobacterial persistors. Antimicrob Agents Chem 1999;43:218-25.
12. Manganelli R, Dubanu E, Tyagi S, Kramer FR, Smith I. Differential expression of 10 sigma factor genes in Mycobacterium tuberculosis. Mol Microbiol 1999;31:715-24.
13. Orme IM. The mouse as a useful model of tuberculosis. Tuberculosis (Edinb) 2003;83:112-5.
14. McCune RM, Tompsett R, McDermott W. Fate of Mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. I. The persistence of drug susceptible bacilli in the tissues despite prolonged antimicrobial therapy. J Exp Med 1956;104:737-62.
15. Orme IM. The latent tuberculosis bacillus (I'll let you know if I ever meet one). Int J Tuberc Lung Dis 2001;5:589-93.
16. McKinney JD, Honer zu Bentrub K, Munoz-Elias EJ et al. Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase. Nature 2000;406:735-8.
17. Wallace JG. The heat resistance of tubercle bacilli in the lungs of infected mice. Am Rev Respir Dis 1961;83:866-71.
18. Flynn JL, Chan J. Immunology of tuberculosis. Annu Rev Immunol 2001;19:93-129.
19. Muñoz-Elias EJ, Timm J, Botha T, Chan WT, Gomez JE, McKinney JD. Replication dynamics of Mycobacterium tuberculosis in chronically infected mice. Infect Immun 2005;73:546-51.
20. Shi L, Jung YJ, Tyagi S, Gennaro ML, North RJ. Expression of Th1-mediated immunity in mouse lungs induces a Mycobacterium tuberculosis transcription pattern characteristic of nonreplicating persistence. Proc Natl Acad Sci USA 2003;100:241-6.
21. Shi L, North R, Gennaro ML. Effect of growth state on transcription levels of genes encoding major secreted antigens of Mycobacterium tuberculosis in the mouse lung. Infect Immun 2004;72:2420-4.
22. Pai SR, Actor JK, Sepulveda E, Hunter RL Jr, Jagannath C. Identification of viable and non-viable Mycobacterium tuberculosis in mouse organs by directed RT-PCR for antigen 85B mRNA. Microb Pathog 2000;28:335-42.
23. Sturgill-Koszycki S, Schlesinger PH, Chakraborty P et al. Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase. Science 1994;263:678-81.
24. MacMicking JD, Taylor GA, McKinney JD. Immune control of tuberculosis by IFN-gamma-inducible LRG-47. Science 2003;302:654-9.
25. Rhoades ER, Orme IM. Susceptibility of a panel of virulent strains of Mycobacterium tuberculosis to reactive nitrogen intermediates. Infect Immun 1997;65:1189-95.
26. Rand L, Hinds J, Springer B, Sander P, Buxton RS, Davis EO. The majority of inducible DNA repair genes in Mycobacterium tuberculosis are induced independently of RecA. Mol Microbiol 2003;50:1031-42.
27. Pinto R, Tang QX, Britton WJ, Leyh TS, Triccas JA. The Mycobacterium tuberculosis cysD and cysNC genes form a stress-induced operon that encodes a tri-functional sulfate-activating complex. Microbiology 2004;150:1681-6.
28. Fritz C, Maass S, Kreft A, Bange FC. Dependence of Mycobacterium bovis BCG on anaerobic nitrate reductase for persistence is tissue specific. Infect Immun 2002;70:286-91.
29. Wayne LG, Hayes LG. Nitrate reduction as a marker for hypoxic shiftdown of Mycobacterium tuberculosis. Tuberc Lung Dis 1998;79:127-32.
30. Stermann M, Sedlacek L, Maass S, Bange FC. A promoter mutation causes differential nitrate reductase activity of Mycobacterium tuberculosis and Mycobacterium bovis. J Bacteriol 2004;186:2856-61.
31. Timm J, Post FA, Bekker LG et al. Differential expression of iron-, carbon-, and oxygen-responsive mycobacterial genes in the lungs of chronically infected mice and tuberculosis patients. Proc Natl Acad Sci USA 2003;100:14321-6.
32. Cardona PJ, Gordillo S, Diaz D et al. Widespread bronchogenic dissemination makes DBA/2 mice more susceptible than C57BL/6 mice to experimental aerosol infection with Mycobacterium tuberculosis. Infect Immun 2003;71:5845-54.
33. James PE, Grinberg OY, Michaels G, Swartz HM. Intraphagosomal oxygen in stimulated macrophages. J Cell Physiol 1995;163:241-7.
34. Grinberg OY, James PE, Swartz HM. Are there significant gradients of pO2 in cells? Adv Exp Med Biol 1998;454:415-23.
35. Fisher MA, Plikaytis BB, Shinnick TM. Microarray analysis of the Mycobacterium tuberculosis transcriptional response to the acidic conditions found in phagosomes. J Bacteriol 2002;184:4025-32.
36. Hellyer TJ, DesJardin LE, Hehman GL, Cave MD, Eisenach KD. Quantitative analysis of mRNA as a marker for viability of Mycobacterium tuberculosis. J Clin Microbiol 1999;37:290-5.
37. Gomez M, Smith I. Determinants of mycobacterial gene expression. In: Hatfull, GF, Jacobs, WR Jr, eds. Molecular Genetics of Mycobacteria. Washington, DC: ASM Press, 2000: 111-30.
38. Saviola B, Woolwine SC, Bishai WR. Isolation of acid-inducible genes of Mycobacterium tuberculosis with the use of recombinase-based in vivo expression technology. Infect Immun 2003;71:1379-88.
39. Williams SJ, Senaratne RH, Mougous JD, Riley LW, Bertozzi CR. 50′-adenosinephosphosulfate lies at a metabolic branch point in mycobacteria. J Biol Chem 2002;277:32606-15.
40. Kuehnel MP, Goethe R, Habermann A et al. Characterization of the intracellular survival of Mycobacterium avium ssp. paratuberculosis: phagosomal pH and fusogenicity in J774 macrophages compared with other mycobacteria. Cell Microbiol 2001;3:551-66.
41. Malik ZA, Thompson CR, Hashimi S, Porter B, Iyer SS, Kusner DJ. Cutting edge: Mycobacterium tuberculosis blocks Ca2+ signaling and phagosome maturation in human macrophages via specific inhibition of sphingosine kinase. J Immunol 2003;170:2811-5.