In vivo efficacy study of the anti-inflammatory properties of Surolan

Canadian Journal of Veterinary Research

Volumn 70, Issue 3, 2006, Pages 234-236

  Bolinder, Anna ^a   Cameron, Kelly ^a   Faubert, Lynn ^a   Wilson, Jeff ^b   Aramini, Jeff ^b   Hare, Jonathan ^c  

^a International Bio Institute Corporation   (Canada)

^b UNIVERSITY OF GUELPH   (Canada)

^c Janssen Animal Health   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONE; ANTIINFLAMMATORY AGENT; MICONAZOLE NITRATE; PHORBOL 13 ACETATE 12 MYRISTATE; POLYMYXIN B; PREDNISOLONE ACETATE; SUROLAN; UNCLASSIFIED DRUG;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ERYTHEMA; EXTERNAL EAR; FEMALE; IN VIVO STUDY; MOUSE; NONHUMAN; SINGLE DRUG DOSE; SKIN EDEMA; SKIN INFLAMMATION; SKINFOLD THICKNESS; SUSPENSION; TREATMENT OUTCOME;

ANALYSIS OF VARIANCE; ANIMALS; ANTI-INFLAMMATORY AGENTS; DISEASE MODELS, ANIMAL; EAR; FEMALE; INFLAMMATION; MICE; MICE, INBRED STRAINS; OTITIS EXTERNA; PREDNISOLONE; RANDOM ALLOCATION; TETRADECANOYLPHORBOL ACETATE; TREATMENT OUTCOME;

EID: 33746456882     PISSN: 08309000     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. McKeever PJ. Otitis externa. Compend Contin Educ Pract Vet 1996;18:759-772.
2. Scott DW, Miller WH, Griffin CE, eds. External ear diseases. In: Muller and Kirk's Small Animal Dermatology. Philadelphia, Pennsylvania: WB Saunders, 2000:1203-1232.
3. Gotthelf L. Small Animal Ear Diseases: an Illustrated Guide. Philadelphia, Pennsylvania: WB Saunders, 2000:87-98.
4. Merchant SR. Medically managing chronic otitis externa and media. Vet Med 1997;92:518-534.
5. Hendricks A, Brooks H, Pocknell A, Bond R. Ulcerative otitis externa responsive to immunosuppressive therapy in two dogs. J Small Anim Pract 2002;43:350-354.
6. Harvey RG, Harari J, Delauche AJ. Etiopathogenesis and classification of otitis externa. In: Ear Diseases of the Dog and Cat. Ames, Iowa: Iowa State University Press, 2001:81-122.
7. Gedek B, Brutzel K, Gerlach R, et al. The role of Pityrosporum pachydermatis in otitis externa of dogs: evaluation of a treatment with miconazole. Vet Rec 1979;104:138-140.
8. Cieslicki M. Die Bedeutung des Kortisonanteils in Otitispräparaten - eine kritische Betrachtung von Kombinations-präparaten. Kleintierpraxis 1991;36:140-150.
9. Kiss G, Radvanyi S, Szigeti G. New combination for the therapy of canine otitis externa. I. Microbiology of otitis externa. J Small Anim Pract 1997;38:51-56.
10. Kiss G, Radvanyi S, Szigeti G. New combination for the therapy of canine otitis externa. II. Efficacy in vitro and in vivo. J Small Anim Pract 1997;38:57-60.
11. Hecht M. Surolan® - Behandlung bei rezidivierender Otitis externa der Hunde. Prakt Tierarzt 1977;11:851-852.
12. Studdert V, Hughes KL. A clinical trial of a topical preparation of miconazole, polymyxin and prednisolone in the treatment of otitis externa in dogs. Aust Vet J 1991;68:193-195.
13. Young JM, De Young LM. Cutaneous models of inflammation for the evaluation of topical and systemic pharmacological agents. In: Chang JY, Lewis AJ, eds. Pharmacological Methods in the Control of Inflammation. New York: Alan R. Liss, 1989:215-231.
14. SAS/STAT User's Guide, version 8. Cary, North Carolina: SAS Institute, 1999.
15. Office of Food Additive Safety, Center for Food Safety and Applied Nutrition, US Food and Drug Administration. Good laboratory practice for nonclinical laboratory studies. Part 58 of Good Laboratory Practices for Designing Toxicology Studies for Petition Submissions and Notifications. Guidance for Submitting Petitions and Notifications. Rockville, Maryland: FDA, 2005. Available at www.cfsan.fda.gov/~dms/opa-pt58.html (last accessed 2006 Mar 14).
16. Canadian Council on Animal Care. Resource materials available at www.ccac.ca/en/CCACΡograms/CCACΡograms_ETC.htm (last accessed 2006 Mar 14).