Analysis of fluconazole effect on Candida albicans viability during extended incubations

Medical Mycology

Volumn 36, Issue 1, 1998, Pages 29-36

  Sohnle, P G ^a,b   Hahn, B L ^a,b   Fassel, T A ^a   Kushnaryov, V M ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Candida albicans viability; Extended incubation; Fluconazole

Indexed keywords

FLUCONAZOLE;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CANDIDIASIS; DRUG DETERMINATION; DRUG POTENCY; DRUG SENSITIVITY; FUNGUS GROWTH; GROWTH INHIBITION; NONHUMAN; TRANSMISSION ELECTRON MICROSCOPY;

CANDIDA ALBICANS; FUNGI;

EID: 33746436188     PISSN: 13693786     EISSN: None     Source Type: Journal    
DOI: 10.1080/02681219880000051     Document Type: Article

References (19)

1. Anaissie E, Bodey GP, Kantarjian H. Azole antifungal agents. Clin Infect Dis 1992; 14(Suppl. 1): S161-9.
2. Hughes CE, Beggs WH. Action of fluconazole (UK-49,858) in relation to other systemic antifungal azoles. J Antimicrob Chemother 1987; 19: 171-4.
3. Sheehan DJ, Espinel-Ingroff A, Moore LS, Webb KCD. Anti-fungal susceptibility testing of yeasts-a brief overview. Clin Infect Dis 1993; 17(Suppl. 2): S494-S500.
4. Sohnle PG, Hahn BL, Erdmann MD. Effect of fluconazole on viability of Candida albicans over extended periods of time. Antimicrob Agents Chemother 1996; 40: 2622-5.
5. Anaissie E, Bodey G, Kantarjian H. Fluconazole therapy for chronic disseminated candidiasis in patients with leukemia and prior amphotericin B therapy. Am J Med 1991; 91: 142-50.
6. Brass C, Galgiani JN, Campbell SC, Stevens DA. Therapy of disseminated or pulmonary coccidioidomycosis with ketoconazole. Rev Infect Dis 1980; 2: 656-60.
7. Dismukes WE, Bradsher RW, Cloud GC, Kauffman CA, Chapman SW, George RB, Stevens DA, Girard WM, Saag MS, Bowles-Patton C and the NIAID Mycoses Study Group. Itraconazole therapy for blastomycosis and histoplasmosis. Am J Med 1992; 93: 489-97.
8. Graybill Jr, Lundberg D, Donovan W, Levine HB, Rodriguez MD, Drutz DJ. Treatment of coccidioidomycosis with ketoconazole-clinical and laboratory studies of 18 patients. Rev Infect Dis 1980; 2: 661-73.
9. Kauffman, CA, Bradley SE, Ross SC, Weber, DR. Hepatosplenic candidiasis-successful treatment with fluconazole. Am J Med 1991; 91: 137-41.
10. Durack, DT, Beeson, PB. Experimental bacterial endocarditis. II. Survival of bacteria in endocardial vegetations. Br J Pathol 1972; 53: 50-53.
11. Sohnle, PG, Hahn, BL. Inhibition of pseudohyphal growth as a neutrophil-mediated host defense mechanism against experimental deep Candida albicans infections in mice. J Lab Clin Med 1993; 121: 235-43.
12. Anaissie EJ, Karyotakis NC, Hachem R, Dignani RC, Rex JH, Paetznick V. Correlation between in vitro and in vivo activity of antifungal agents against Candida species. J Infect Dis 1994; 170: 384-89.
13. Galgiani JN. Susceptibility of Candida albicans and other yeasts to fluconazole-relation between in vitro and in vivo studies. Rev Infect Dis 1990; 12(Suppl. 3): S272-75.
14. Troke PF, Andrews RJ, Pye GW, Richardson K. Fluconazole and other azoles-translation of in vitro activity to in vivo and clinical efficacy. Rev Infect Dis 1990; 12(Suppl. 3): S276-80.
15. National Committee on Clinical Laboratory Standards. Reference method for broth dilution antifungal susceptibility testing of yeasts; tentative standard. NCCLS document M27-T. NCCLS, Wayne, PA 1995.
16. Gujral S, Brummer E, Stevens DA. Role of extended culture time on synergy of fluconazole and human monocyte-derived macrophages in clearing Candida albicans. J Infect Dis 1996; 174: 888-90.
17. Isaacson DM, Tolman EL, Tobia AJ, Rosenthale ME, McGuire JL, Van den Bossche H, Janssen PAJ. Selective inhibition of 14α-desmethyl sterol synthesis in Candida albicans by terconazole, a new triazole antimycotic. J Antimicrob Chemother 1988; 21: 333-43.
18. Van den Bossche H, Willemsens G, Cools W, Lauwers WFJ, Le Jeune L. Biochemical effects of miconazole on fungi. II. Inhibition of ergosterol biosynthesis in Candida albicans. Chem Biol Interact 1978; 21: 59-78.
19. Van den Bossche H. Biochemical effects of miconazole on fungi. I. Effects on the uptake and/or utilization of purines, pyrimidines, nucleosides, amino acids and glucose by Candida albicans. Biochem Pharmacol 1974; 23: 887-99.