Does hydrocortisone modify the in vitro susceptibility of Aspergillus fumigatus to itraconazole and amphotericin B?

Medical Mycology

Volumn 36, Issue 2, 1998, Pages 69-73

  Ramondenc, I ^a,b   Pinel, C ^a   Ambroise Thomas, P ^a   Grillot, R ^a  

^a UNIV GRENOBLE ALPES   (France)

^b CNRS   (France)

Author keywords

Antifungal susceptibility; Aspergillus fumigatus; Hydrocortisone

Indexed keywords

AMPHOTERICIN B; HYDROCORTISONE; ITRACONAZOLE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CELL FUNCTION; DISEASE PREDISPOSITION; HORMONE ACTION; IN VITRO STUDY; LIGAND BINDING; NONHUMAN; RISK FACTOR;

AMPHOTERICIN B; ANTIFUNGAL AGENTS; ASPERGILLUS FUMIGATUS; HYDROCORTISONE; ITRACONAZOLE; MICROBIAL SENSITIVITY TESTS;

EID: 33746433970     PISSN: 13693786     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-280X.1998.00131.x     Document Type: Article

References (29)

1. Bodey G, Bueltmann B, Duguiol W, et al. Fungal infections in cancer patients: an international autopsy survey. Eur J Clin Microbiol Infect Dis 1992; 11: 99-109.
2. Morrison VA, Haakc RJ, Weisfort DJ. The spectrum of non-Candida fungal infections following bone marrow transplantation. Med (Baltimore) 1993; 72: 78-89.
3. Wallace MR, Kanak RJ, Newton JA, Kennedy CA. Invasive aspergillosis in patients with AIDS. Clin Infect Dis 1994; 19: 222.
4. Gustafson TL, Schaffner W, Lavely GB, Stratton CW, Johnson HK, Huthson RH. Invasive aspergillosis in renal transplant recipients: correlation with corticosteroid therapy. J Infect Dis 1983; 148: 230-8.
5. Kappe, R, Levitz, SM, Cassone, A, Wasshburn, RG. Mechanisms of host defense against fungal infection. J Med Vet Mycol 1992; 30 (Suppl. 1): 167-77.
6. Schaffner, A, Douglas, H, Braude, A, Selective protection against conidia by monuclear and against mycelia by polymorphonuclear phagocytes in resistance to Aspergillus. J Clin Invest 1982; 69: 617-631.
7. Diamond RD, Clark RA. Damage to Aspergillus fumigatus and Rhizopus oryzea hyphac by oxidative and non-oxidative microbial products of human neutrophils in vitro. Infect Immun 1982; 38: 487-95.
8. Clemons KV, Schär G, Price Stover E, Feldman D, Stevens, DA. Dermatophyte-hormone relationships: characterization of progesterone-binding specificity and growth inhibition in the genera Trichophyton and Microsporum. J Clin Microbiol 1988; 26: 2110-15.
9. Salazar ME, Restrepo A, Stevens DA. Inhibition by estrogens of conidium-to-yeast conversion in the fungus Paracoccidioides brasiliensis. Infect Immun 1988; 56: 711-13.
10. Loose DS, Schurman, DJ, Feldman D. A corticosteroid binding protein and endogenous ligand in Candida albicans indicating a possible steroid-receptor system. Nature 1981; 293: 477-9.
11. Madani ND, Malloy PJ, Rodriguez-Pombo P, Krishnan AV, Feldman D. Candida albicans estrogen-binding protein gene encodes an oxidoreductase that is inhibited by estradiol. Proc Natl Acad Sci USA 1994; 91: 922-6.
12. Malloy PJ, Zhao X, Madani ND, Feldman D. Cloning and expression of the gene from Candida albicans that encodes a high-affinity corticosteroid-binding protein. Proc Natl Acad Sci USA 1993; 90: 1902-6.
13. Ng TTC, Robson DG, Denning DW. Hydrocortisone-enhanced growth of Aspergillus spp: implication for pathogenesis. Microbiol 1994; 140: 2475-9.
14. Berenguer J, Allende MC, Lee JW, et al. Pathogenesis of pulmonary aspergillosis: granulocytopenia versus cyclosporine and methylprednisolone-induced immunosuppression. Am J Respir Crit Care Med 1995; 152: 1079-86.
15. Grillot R, Lebeau B, Ambroise-Thomas P. L'aspergillose invasive: conduite du diagnostic mycologique. Pathol Biol 1994; 42: 675-82.
16. Fridkin SK, Jarvis WR. Epidemiology of nosocomial fungal infections. Clin Microhbiol Rev 1996; 9: 499-511.
17. Denning DW. Therapeutic outcome in invasive aspergillosis. Clin Infect Dis 1996; 23: 608-15.
18. Pinel C, Monod M, Ambroise-Thomas P, Grillot R. Westernblot detection of IgG anti-Aspergillus fumigatus elastase in sera of patients with aspergillosis. J Med Vet Mycol 1994; 32: 231-4.
19. National Commitee for Clinical Laboratory Standards. Reference method for broth dilution antifungal susceptibility testing of yeasts; proposed standard. Document M27-P. National Commitee for Clinical Laboratory Standards. Villanova, Pa, 1992.
20. Mukherjee A, Banerjee S, Mahato SB. Metabolism of progesterone by Aspergillus fumigatus. J Steroid Biochem 1982; 17: 443-6.
21. Zakelj-Mavric M, Kastelic-Suhadolc T, Plemenitas A, Lanisnik Rizner T, Belic, I. Steroid hormone signalling and fungi. Comp Biochem Physiol 1995; 112B: 637-42.
22. Kerridge D. Mode of action of clinically important antifungal drugs. Adv Microb Physiol 1986; 27: 1-72.
23. Denning DW, Lee JY, Hostetler JS, et al. NIAID mycoses study group multicenter trial of oral itraconazole therapy for invasive aspergillosis. Am J Med 1994; 97: 135-44.
24. Vanden Bossche H, Marichal P, Gorrens J, Bellens D, Moereels H, Janssen PAJ. Mutation in cytochrome P450-dependant 14α demethylase results in decreased affinity for azole antifungals. Biochem Soc. Trans 1990; 18: 56-9.
25. Shimokawa O, Nakayama H. Increased sensitivity of Candida albicans cells accumulating 14α-methylated sterols to active oxygen: possible relevance to in vivo efficacies of azole antifungal agents. Antimicrob Agents Chemother 1992; 36: 1626-9.
26. Smith KE, Ahmed, F, Wiliams RAD, Kelly SL. Microbial transformation of steroids - VIII. Transformation of progesterone by whole cells and microsomes of Aspergillus fumigatus. J Steroid Biochem Molec Biol 1994; 49: 93-100.
27. Smith KE, Ahmed F, Antoniou T. Microbial transformation of steroids. Biochem Soc Trans 1993; 21: 1077-80.
28. Van den Brink JM, van den Hondel CAMJJ, van Gorcom RFM. Optimization of the benzoate-inducible benzoate p-hydroxylase cytochrome P450 enzyme system in Aspergillus niger. Appl Microbiol Biotechnol 1996; 46: 360-4.
29. Baybutt HN, Holboer, F. Inhibition of macrophage differentiation and function by cortisol. Endocrinology 1990; 127: 476-80.