Clinical value of vesical leukoplakia and evaluation of the neoplastic risk by mutation analyses of the tumor suppressor gene TP53

International Journal of Urology

Volumn 13, Issue 8, 2006, Pages 1092-1097

  Staack, Andrea ^a   Schlechte, Horst ^a   Sachs, Markus ^a   Kristiansen, Glen ^a   Burkhardt, Mick ^a   Schnorr, Dietmar ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Cystoscopy; Epithelial heterotopy; TP53 mutations; Vesical leukoplakia

Indexed keywords

DNA; PROTEIN P53;

ADOLESCENT; ADULT; AGED; ARTICLE; BLADDER CANCER; BLADDER LEUKOPLAKIA; CANCER RISK; CONTROLLED STUDY; COURSE EVALUATION; CYSTOSCOPY; CYTOLOGY; DIAGNOSTIC VALUE; DNA ISOLATION; EVALUATION; EXON; FEMALE; FOLLOW UP; HUMAN; LEUKOPLAKIA; MAJOR CLINICAL STUDY; MUTATIONAL ANALYSIS; PRECANCER; PRIORITY JOURNAL; RISK ASSESSMENT; SPONTANEOUS MUTATION; TRANSITIONAL CELL CARCINOMA; TUMOR LOCALIZATION; TUMOR SUPPRESSOR GENE; TUMOR VOLUME; URINALYSIS; URINE SEDIMENT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, TRANSITIONAL CELL; CYSTOSCOPY; DNA MUTATIONAL ANALYSIS; ELECTROPHORESIS; FEMALE; FOLLOW-UP STUDIES; GENES, P53; HUMANS; LEUKOPLAKIA; MIDDLE AGED; POLYMERASE CHAIN REACTION; RISK FACTORS; URINARY BLADDER NEOPLASMS;

EID: 33746430555     PISSN: 09198172     EISSN: 14422042     Source Type: Journal    
DOI: 10.1111/j.1442-2042.2006.01503.x     Document Type: Article

References (21)

1. Cifuentes L. Epithelium of vaginal type in the female trigone-the clinical problem of trigonitis. J. Urol. 1947; 9: 653-5.
2. Bettex M, Oesch I, Zimmermann A. Granular cystitis in girls. Long-term follow-up. Eur. Urol. 1988; 15: 235-6.
3. Hojgaard AD, Jessen AL. [Bladder leukoplakia]. Ugeskr. Laeger. 1991; 153: 2408-9.
4. Benson RC Jr, Swanson SK, Farrow GM. Relationship of leukoplakia to urothelial malignancy. J. Urol. 1984; 131: 507-11.
5. Reece RW, Koontz WW Jr. Leukoplakia of the urinary tract: a review. J. Urol. 1975; 114: 165-71.
6. Shibuya H, Amagasa T, Seto K, Ishibashi K, Horiuchi J, Suzuki S. Leukoplakia-associated multiple carcinomas in patients with tongue carcinoma. Cancer 1986; 57: 843-6.
7. Kozarek RA, Sanowski RA. Caustic cicatrization of the pharynx associated with dysphagia and premalignant mucosal changes. Am. J. Gastroenterol. 1982; 77: 5-8.
8. Boutselis JG. Intraepithelial carcinoma of the vulva. Am. J. Obstet. Gynecol. 1972; 113: 733-8.
9. Sakoda R, Oka M, Nakashima K. Leukoplakia of the penis - bleomycin treatment. Br. J. Urol. 1978; 50: 355.
10. Kretschmer HL. Leukoplakia of the bladder and ureter. Surg. Gynecol. Obstet. 1920; 31: 325.
11. Langman J. Medizinische Embryologie. 8. Auflage edn. Georg Thieme Verlag, Stuttgart, 1989.
12. Staack A, Hayward SW, Baskin LS, Cunha GR. Molecular, cellular and developmental biology of urothelium as a basis of bladder regeneration. Differentiation 2005; 73: 121-33.
13. Mueller SC, Thueroff JW, Rumpelt HJ. Urothelial leukoplakia: new aspects of etiology and therapy. J. Urol. 1987; 137: 979-83.
14. Widran J, Sanchez R, Gruhn J. Squamous metaplasia of the bladder: a study of 450 patients. J. Urol. 1974; 112: 479-82.
15. Mostofi FK. Potentialities of bladder epithelium. J. Urol. 1954; 71: 705-14.
16. Scholz RB, Milde-Langosch K, Jung R et al. Rapid screening for Tp53 mutations by temperature gradient gel electrophoresis: a comparison with SSCP analysis. Hum. Mol. Genet. 1993; 2: 2155-8.
17. Schlechte HH, Schnorr D, Loning T, Rudolph BD, Pohrt UM, Loening SA. Mutation of the tumor suppressor gene p53 in human prostate and bladder cancers - investigation by temperature gradient gel electrophoresis (TGGE). J. Urol. 1997; 157: 1049-53.
18. Scheifele C, Schlechte H, Bethke G, Reichart PA. [Detection of TP53-mutations in brush biopsies from oral leukoplakias]. Mund Kiefer Gesichtschir. 2002; 6: 410-14.
19. Hojgaard AD, Jessen AL. A case of vesical leukoplakia. Acta Obstet. Gynecol. Scand. 1991; 70: 623-4.
20. Burkhard FC, Blick N, Hochreiter WW, Studer UE. Urinary urgency and frequency, and chronic urethral and/or pelvic pain in females. Can doxycycline help? J. Urol. 2004; 172: 232-5.
21. Koss LG. Koss's Diagnostics Cytology and its Histopathologic Basis, 4th edn. J. B. Lippincott Company Philadelphia, Philadelphia, 1979.