Superinfection of human immunodeficiency virus type 1 (HIV-1) to cell clone persistently infected with defective virus induces production of highly cytopathogenic HIV-1

Microbes and Infection

Volumn 8, Issue 7, 2006, Pages 1773-1782

  Iwabu, Yukie ^a   Goto, Toshiyuki ^b   Tsuji, Shotaro ^a   Warachit, Jiranan ^a   Li, Gui Mei ^a   Shoji, Sanae ^a   Kameoka, Masanori ^a   Ikuta, Kazuyoshi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Complementation; Cytopathogenicity; HIV 1; Subtype; Superinfection

Indexed keywords

POL PROTEIN;

ANIMAL CELL; ARTICLE; CELL CLONE; CELL ISOLATION; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; GENE INSERTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MOLECULAR MECHANICS; NONHUMAN; PRIMARY INFECTION; PRIORITY JOURNAL; PROVIRUS; RAT; SUPERINFECTION; VIRUS PARTICLE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 33746410958     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2006.02.015     Document Type: Article

References (30)

1. Katz R.A., and Skalka A.M. Generation of diversity in retroviruses. Annu. Rev. Genet. 24 (1990) 409-445
2. Takebe Y., Kusagawa S., and Motomura K. Molecular epidemiology of HIV: tracking AIDS pandemic. Pediatr. Int. 46 (2004) 236-244
3. Ou C.Y., Takebe Y., Weniger B.G., Luo C.C., Kalish M.L., Auwanit W., Yamazaki S., Gayle H.D., Young N.L., and Schochetman G. Independent introduction of two major HIV-1 genotypes into distinct high-risk populations in Thailand. Lancet 341 (1993) 1171-1174
4. Ramos A., Hu D.J., Nguyen L., Phan K.-O., Vanichseni S., Promadei N., Choopanya K., Callahan M., Young N.L., McNicholl J., Mastro T.D., Folks T.M., and Subbarao S. Intersubtype human immunodeficiency virus type 1 superinfection following seroconversion to primary infection in two injection drug users. J. Virol. 76 (2002) 7444-7452
5. Tovanabutra S., Watanaveeradej V., Viputtikul K., De Souza M., Razak M.H., Suriyanon V., Jittiwutikarn J., Sriplienchan S., Nitayaphan S., Benenson M.W., Sirisopana N., Renzullo P.O., Brown A.E., Robb M.L., Beyrer C., Celentano D.D., McNeil J.G., Birx D.L., Carr J.K., and McCutchan F.E. A new circulating recombinant form, CRF15_01B, reinforces the linkage between IDU and heterosexual epidemics in Thailand. AIDS Res. Hum. Retrov. 19 (2003) 561-567
6. Lori F., Hall L., Lusso P., Popovic M., Markham P., Franchini G., and Reits Jr. M.S. Effect of reciprocal complementation of two defective human immunodeficiency virus type 1 (HIV-1) molecular clones on HIV-1 cell tropism and virulence. J. Virol. 66 (1992) 5553-5560
7. Cao Y., Ho D.D., Todd J., Kokka R., Urden M., Lifson J.D., Piatak Jr. M., Chen S., Hahn B.H., Saag M.S., and Shaw G.M. Clinical evaluation of branched DNA signal amplification for quantifying HIV type 1 in human plasma. AIDS Res. Hum. Retrov. 11 (1995) 353-361
8. Ho D.D., Neumann A.U., Perelson A.S., Chen W., Leonard J.M., and Markowitz M. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 373 (1995) 123-126
9. Chun T.-W., Carruth L., Finzi D., Shen X., DiGiuseppe J.A., Taylor H., Hermankova M., Chadwick K., Margolick J., Quinn T.C., Kuo Y.H., Brookmeyer R., Zeiger M.A., Barditch-Crovo P., and Siliciano R.F. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 387 (1997) 183-188
10. Coffin J.M. HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. Science 267 (1995) 483-489
11. Xin K.Q., Ma X.H., Crandall K.A., Bukawa H., Ishigatsubo Y., Kawamoto S., and Okuda K. Dual infection with HIV-1 Thai subtype B and E. Lancet 346 (1995) 1372-1373
12. +T-cell responses containing replication of the primary virus. Nature 420 (2002) 434-439
13. Gonzales M.J., Delwart E., Rhee S.-Y., Tsui R., Zolopa A.R., Taylor J., and Shafer R.W. Lack of detectable human immunodeficiency virus type 1 superinfection during 1072 person-years of observation. J. Infect. Dis. 188 (2003) 397-405
14. Kishi M., Tokunaga K., Zhang Y.H., Bahmani M.K., Kakinuma M., Nonoyama M., Lai P.K., and Ikuta K. Superinfection of a defective human immunodeficiency virus type 1 provirus-carrying T cell clone with vif or vpu mutants gives cytopathic virus particles by homologous recombination. AIDS Res. Hum. Retrov. 11 (1995) 45-53
15. Mo H., Lu L., Pithawalla R., Kempf D.J., and Molla A. Complementation in cells cotransfected with a mixture of wild-type and mutant human immunodeficiency virus (HIV) influences the replication capacities and phenotypes of mutant variants in a single-cycle HIV resistance assay. J. Clin. Microbiol. 42 (2004) 4169-4174
16. Little S.J., Riggs N.L., Chowers M.Y., Fitch N.J., Richman D.D., Spina C.A., and Guatelli J.C. Cell surface CD4 downregulation and resistance to superinfection induced by a defective provirus of HIV-1. Virology 205 (1994) 578-582
17. Boulerice F., Li X.G., Lvovich A., and Wainberg M.A. Recovery of infectious human immunodeficiency virus type 1 after fusion of defectively infected clones of U-937 cells. J. Virol. 65 (1991) 5589-5592
18. Goto T., Ikuta K., Zhang J.J., Morita C., Sano K., Komatsu M., Fujinaga H., Kato S., and Nakai M. The budding of defective human immunodeficiency virus type 1 (HIV-1) particles from cell clones persistently infected with HIV-1. Arch. Virol. 111 (1990) 87-101
19. +T lymphocytes. J. Virol. 77 (2003) 10304-10313
20. Tokunaga K., Kojima A., Kurata T., Ikuta K., Inubushi R., Shimano R., Kawamura M., Akari H., Koyama A.H., and Adachi A. Producer cell-dependent requirement of the Nef protein for efficient entry of HIV-1 into cells. Biochem. Biophys. Res. Commun. 250 (1998) 565-568
21. Ikuta K., Morita C., Miyake S., Ito T., Okabayashi M., Sano K., Nakai M., Hirai K., and Kato K. Expression of human immunodeficiency virus type 1 (HIV-1) Gag antigens on the surface of a cell line persistently infected with HIV-1 that highly expresses HIV-1 antigens. Virology 170 (1989) 408-417
22. Matsuo K., Nishino Y., Kimura T., Yamaguchi R., Yamazaki A., Mikami T., and Ikuta K. Highly conserved epitope domain in major core protein p24 is structurally similar among human, simian, and feline immunodeficiency viruses. J. Gen. Virol. 73 (1992) 2445-2450
23. Saitoh A., Tanaka N., Nakata A., Ikuta K., and Shinagawa H. A unique monoclonal antibody that recognizes mature p17 of HIV-1 but not its precursor. Microbiol. Immunol. 36 (1992) 105-111
24. Kameoka M., Kimura T., Okada Y., Fujinaga K., Nakaya T., Takahashi H., Kishi M., and Ikuta K. High susceptibility of U937-derived subclones to human immunodeficiency virus type 1 infection correlates with accumulation of unintegrated circular viral DNA. Virus Genes. 12 (1996) 117-129
25. Saadat M., Takahashi H., Bahmani M.K., Ikuta K., and Yoshida M.C. Does human immunodeficiency virus type-1 integrate in chromosomes randomly?. Chromosome Sci. 2 (1998) 5-8
26. Bahmani M.K., Kameoka M., Nakaya T., Fujinaga K., Zhong Q., Takahashi H., Nakano T., Nakai M., Ueda S., Jones J.M., Luftig R.B., and Ikuta K. Production of doughnut-shaped, protease-defective particles from a human T cell clone carrying a provirus with specific mutations in the env, pol, vpr, and nef genes. AIDS Res. Hum. Retrov. 13 (1997) 523-526
27. Ohki K., Kishi M., Nishino Y., Sumiya M., Kimura T., Goto T., Nakai M., and Ikuta K. Non-infectious doughnut-shaped human immunodeficiency virus type 1 can induce syncytia mediated by fusion of the particles with CD4-positive cells. J. Acq. Imm. Def. Syndr. 4 (1991) 1233-1240
28. Bahmani M.K., Kameoka M., Goto T., Sano K., Luftig R.B., and Ikuta K. Fusion of uninfected T-cells occurs with immature HIV-1 protease-mutant, but not morphologically similar protease inhibitor derived particles. Virus Res. 66 (2000) 131-137
29. Kinomoto M., Yokoyama M., Sato H., Kojima A., Kurata T., Ikuta K., Sata T., and Tokunaga K. Amino acid 36 in the human immunodeficiency virus type 1 gp41 ectodomain controls fusogenic activity: implications for the molecular mechanism of viral escape from a fusion inhibitor. J. Virol. 79 (2005) 5996-6004
30. Jung A., Maier R., Vartanian J.-P., Bocharov G., Jung V., Fischer U., Meese E., Wain-Hobson S., and Meyerhans A. Recombination: multiply infected spleen cells in HIV patients. Nature 418 (2002) 144