Human herpesvirus-8: Beyond Kaposi's

Israel Medical Association Journal

Volumn 8, Issue 7, 2006, Pages 489-493

  Rimar, Doron ^a,b   Rimar, Yossi ^a,b   Keynan, Yoav ^a,b  

^a CARMEL MEDICAL CENTER   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Bone marrow suppression; Hemophagocytic syndrome; Human herpesirus 8; Kaposi's sarcoma associated herpesvirus; Primary pulmonary hypertension

Indexed keywords

ACICLOVIR; ADEFOVIR; ALPHA INTERFERON; ANTIVIRUS AGENT; DOXORUBICIN; FOSCARNET; GAMMA INTERFERON; GANCICLOVIR; GLYCYRRHIZIC ACID; PENCICLOVIR;

ANGIOFOLLICULAR LYMPH NODE HYPERPLASIA; CELL PROLIFERATION; CLINICAL TRIAL; DISEASE ASSOCIATION; ENDOTHELIUM; HUMAN; HUMAN HERPESVIRUS 8; IMMUNE DEFICIENCY; IMMUNOCOMPETENCE; KAPOSI SARCOMA; MONONUCLEOSIS; PRIMARY EFFUSION LYMPHOMA; PULMONARY HYPERTENSION; REVIEW; VIRUS INFECTION; VIRUS TRANSMISSION;

ADULT; ANTIVIRAL AGENTS; BONE MARROW; CHILD; HERPESVIRUS 8, HUMAN; HUMANS; HYPERTENSION, PULMONARY; IMMUNOCOMPROMISED HOST; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MALE; MOLECULAR BIOLOGY; SARCOMA, KAPOSI;

EID: 33746400491     PISSN: 15651088     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (33)

1. Chang Y, Cesarman E, Pessin MS, et al. Identification of herpesvirus-like sequences in AIDS-associated Kaposi's sarcoma. Science 1994;266:1865-9.
2. Schulz TF. Epidemiology of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8. Adv Cancer Res 1999;76:121-60.
3. Neipel F, Albrecht J, Fleckenstein B. Human herpesvirus-8 - the first human Rhadinovirus. J Natl Cancer Inst Monogr 1998;23:73-7.
4. De Paoli P. Human herpesvirus 8: an update. Microbes Infect 2004;6:328-35.
5. Zong D, Ciufo D, Alcendor D, et al. High level variability in the ORF K1 membrane protein gene at the left end of the Kaposi's sarcoma-associated herpesvirus genome defines four major virus subtypes and multiple variants or clades in different human populations. J Virol 1999;73:4156-70.
6. Miller C, Heston L, Grogan E, et al. Selective switch between latency and lytic replication of Kaposi's sarcoma herpesvirus and Epstein-Barr virus in dually infected body cavity lymphoma cells. J Virol 1997;71:314-24.
7. Pauk J, Huang ML, Brodie SJ, et al. Mucosal shedding of human herpesvirus 8 in men. N Engl J Med 2000;343:1369-77.
8. Dukers NT, Rezza G. Human herpesvirus 8 epidemiology: what we do and do not know. AIDS 2003;17:1717-30.
9. Rezza G, Copobianchi M, Serraino D, et al. HHV-8 shedding among HIV-infected women. J Acquir Immune Defic Syndr 2001;28:103-4.
10. Blackbourn DJ, Osmond D, Levy JA, Lennette ET. Increased human herpesvirus 8 seroprevalence in young homosexual men who have multiple sex contacts with different partners. J Infect Dis 1999;179:237-9.
11. Andreoni M, Sarmati L, Nicastri E, et al. Primary human herpesvirus 8 infection in immunocompetent children. JAMA 2002;287: 1295-300.
12. Chen RL, Lin JC, Wang PJ, Lee CP, Hsu YH. Human herpesvirus 8-related childhood mononucleosis: a series of three cases. Pediatr Infect Dis J 2004;23(7):671-4.
13. Wang QJ, Jenkins FJ, Jacobson LP, et al. Primary human herpesvirus 8 infection generates a broadly specific CD8(+) T-cell response to viral lytic cycle proteins. Blood 2001;97:2366-73.
14. Luppi M, Barozzi P, Schulz TF, et al. Nonmalignant disease associated with human herpesvirus 8 reactivation in patients who have undergone autologous peripheral blood stem cell transplantation. Blood 2000;96:2355-7
15. Oksenhendler E, Cazals-Hatem D, Schulz TF, et al. Transient angiolymphoid hyperplasia and Kaposi's sarcoma after primary infection with human herpesvirus 8 in a patient with human immunodeficiency virus infection. N Engl J Med 1998;338:1585-90.
16. Luppi M, Barozzi P, Schulz TF, et al. Bone marrow failure associated with human herpesvirus 8 infection after transplantation. N Engl J Med 2000;343:1378-85.
17. Luppi M, Barozzi P, Rasini V, et al. Severe pancytopenia and hemophagocytosis after HHV-8 primary infection in renal transplant patient successfully treated with foscarnet. Transplantation 2002;74:131-2.
18. Fardet L, Blum L, Kerob D, et al. Human herpesvirus 8-associated hemophagocytic lymphohystiocytosis in human immunodeficiency virus-infected patients. Clin infect Dis 2003;37:285-91
19. Sanchez-Velasco P, Ocejo-Vinyals JG, Flores R, Gomez-Roman JJ, Lozano MJ, Leyva-Cobian F. Simultaneous multiorgan presence of human herpesvirus 8 and restricted lymphotropism of Epstein-Barr virus DNA sequences in a human immunodeficiency virus-negative immunodeficient infant. J Infect Dis 2001;183:338-42.
20. Cool CD, Rai PR, Yeager ME, et al. Expression of human herpesvirus 8 in primary pulmonary hypertension. N Engl J Med 2003;349:1113-22
21. Katano H, Ito K, Shibuya K, Saji T, Sato Y, Sata T. Lack of human herpes virus 8 infection in lungs of Japanese patients with primary pulmonary hypertension. J Infect Dis 2005;191:743-5.
22. Daibata M, Miyoshi I, Taguchi H, et al. Absence of human herpesvirus 8 in lung tissues from Japanese patients with primary pulmonary hypertension. Respir Med 2004;98:1231-2.
23. Henke-Gendo C, Schulz TF, Hoeper MM. HHV-8 in pulmonary hypertension. N Engl J Med 2004;350:194-5.
24. Laney AS, De Marco TD, Peters JS, et al. Kaposi sarcoma-associated herpesvirus and primary pulmonary hypertension. Chest 2005;127:762-7.
25. Montani D, Marcelin AG, Sitbon O, Calvez V, Simonneau G, Humbert M. Human herpes virus 8 in HIV and non-HIV infected patients with pulmonary arterial hypertension in France. AIDS 2005;19:1239-40.
26. Nicastri F, Vizza CD, Carletti F, et al. Human herpesvirus 8 and pulmonary hypertension. Emerg Infect Dis 2005;11(9):1480-2.
27. Tang YW, Johnson JE, Browning PJ, et al. Herpesvirus DNA is consistently detected in lungs of patients with idiopathic pulmonary fibrosis. J Clin Microbiol 2003;41(6):2633-40.
28. Antman K, Chang Y. Kaposis sarcoma. N Engl J Med 2000;342(14): 1027-38.
29. Dagna L, Broccolo F, Paties CT, et al. A relapsing inflammatory syndrome and active human herpesvirus 8 infection. N Engl J Med 2005;353(2):156-63.
30. Hengge UR, Ruzicka T, Tyring SK, et al. Update on Kaposi's sarcoma and other HHV8 associated diseases. Part I: Epidemiology, environmental predispositions, clinical manifestations, and therapy. Lancet infect Dis 2002;2(5):281-92.
31. Klass CM, Offermann MK. Targeting human herpesvirus-8 for treatment of Kaposi's sarcoma and primary effusion lymphoma. Curr Opin Oncol 2005;17(5):447-55.
32. Curreli F, Friedman-Kien AE, Flore O. Glycyrrhizic acid alters Kaposi sarcoma-associated herpesvirus latency, triggering p53-mediated apoptosis in transformed B lymphocytes. J Clin Invest 2005;115(3):642-52.
33. Pozharskaya VP, Weakland LL, Zimring JC, et al. Short duration of elevated vIRF-1 expression during lytic replication of human herpesvirus 8 limits its ability to block antiviral responses induced by alpha interferon in BCBL-1 cells. J Virol 2004;78(12):6621-35.