Duplicated insertion mutation in the microtubule-associated protein Spag5 (astrin/MAP126) and defective proliferation of immature Sertoli cells in rat hypogonadic (hgn/hgn) testes

Reproduction

Volumn 132, Issue 1, 2006, Pages 79-93

  Suzuki, Hiroetsu ^a   Yagi, Mio ^a   Suzuki, Katsushi ^a  

^a NIPPON VETERINARY AND LIFE SCIENCE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MICROTUBULE ASSOCIATED PROTEIN; SPERM ASSOCIATED ANTIGEN 5; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MATURATION; CELL PROLIFERATION; CHROMOSOME 10; CONTROLLED STUDY; EXON; FEMALE; GENE DUPLICATION; GENE FUNCTION; GENE INSERTION; GENE LOCATION; GENE LOCUS; GENE MUTATION; HYPOGONADISM; IMMUNOHISTOCHEMISTRY; MALE; MITOSIS SPINDLE; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PERINATAL PERIOD; PRIORITY JOURNAL; SERTOLI CELL; TESTIS DEVELOPMENT;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BASE SEQUENCE; BIOLOGICAL MARKERS; CELL CYCLE PROTEINS; CELL PROLIFERATION; DNA, COMPLEMENTARY; GENETIC LINKAGE; HUMANS; HYPOGONADISM; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; LINKAGE (GENETICS); MALE; MICE; MICE, MUTANT STRAINS; MITOTIC SPINDLE APPARATUS; MODELS, ANIMAL; MOLECULAR SEQUENCE DATA; MUTATION; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SERTOLI CELLS; STAINING AND LABELING;

ANIMALIA;

EID: 33746392960     PISSN: 14701626     EISSN: None     Source Type: Journal    
DOI: 10.1530/rep.1.01104     Document Type: Article

References (36)

1. Chang MS, Huang CJ, Chen ML, Chen ST, Fan CC, Chu JM, Lin WC & Yang YC 2001 Cloning and characterization of hMAP126, a new member of mitotic spindle-associated proteins. Biochemical and Biophysical Research Communications 287 116-121.
2. Chang MS, Chen CYa, Huang CJ, Fan CC, Chu JM & Yang YC 2003 Expression and promoter analysis of mouse mastrin gene. Biochemical and Biophysical Research Communications 307 491-497.
3. Clermont Y & Perey B 1957 Quantitative study of the cell population of the seminiferous tubules in immature rats. American Journal of Anatomy 100 241-267.
4. Fitzgerald CJ, Oko RJ & Van der Hoorn FA 2006 Rat Spag5 associates in somatic cells with endoplasmic reticulum and microtubules but in spermatozoa with outer dense fibers. Molecular Reproduction and Development 73 92-100.
5. Gruber J, Harborth J, Schnabel J, Weber K & Hatzfeld M 2002 The mitotic-spindle-associated protein astrin is essential for progression through mitosis. Journal of Cell Science 115 4053-4059.
6. Hakamata Y, Kikukawa K, Kamei T, Suzuki K, Taya K & Sasamoto S 1988 A new male hypogonadism mutant rat (hgn/hgn): concentrations of testosterone (T), luteinizing hormone (LH), and follicle-stimulating hormone (FSH) in the serum and the responsiveness of accessory sex organs to exogenous T, FSH, human chorionic gonadotropin, and luteinizing hormone-releasing hormone. Biology of Reproduction 38 1145-1153.
7. Hamada T, Tashiro K, Tada H, Inazawa J, Shirozu M, Shibahara K, Nakamura T, Martina N, Nakano T & Honjo T 1996 Isolation and characterization of a novel secretory protein, stromal cell-derived factor-2 (SDF-2) using the signal sequence trap method. Gene 176 211-214.
8. Ketola J, Rahman N, Toppari J, Bielinska M, Porter-Tinge SB, Tapanainen JS, Huhtaniemi IT, Wilson DB & Heikinheimo M 1999 Expression and regulation of transcription factors GATA-4 and GATA-6 in developing mouse testis. Endocrinology 140 1470-1480.
9. Kobayashi A. Higashide T, Hamasaki D, Kubota S, Sakuma H, An W, Fujimaki T, McLaren MJ, Weleber RG & Inana G 2000 HRG4 (Unc119) mutation found in cone-rod dystrophy causes retinal degeneration in at transgenic model. Investigative Ophthalmology and Visual Science 41 3268-3277.
10. Kukita A, Mukai T, Miyata T & Hori K 1988 The structure of brain-specific rat aldolase C mRNA and the evolution of aldolase isozyme genes. European Journal of Biochemistry 171 471-478.
11. Kuroda T, Lee MM, Haqq CM, Powell DM, Manganaro TF & Donahoe PK 1990 Mullerian inhibiting substance ontogeny and its modulation by follicle-stimulating hormone in the rat testes. Endocrinology 127 1825-1832.
12. Mack GJ & Compton DA 2001 Analysis of mitotic microtubule-associated proteins using mass spectrometry identifies astrin, a spindle-associated protein. PNAS 98 14434-14439.
13. Ohishi K, Inoue N & Kinoshita T 2001 PIG-S and PIG-T, essential for GPI anchor attachment to proteins, from a complex with GAA1 and GP18. EMBO Journal 20 4088-4098.
14. Paranko J, Kallajoki M, Pelliniemi LJ, Lehto VP & Virtanen I 1986 Transient coexpression of cytokeratin and vimentin in differentiating rat Sertoli cells. Developmental Biology 117 35-44.
15. Redenbach DM & Boekelheide K 1994 Microtubules are oriented with their minus-ends directed apically before tight junction formation in rat Sertoli cells. European Journal of Cell Biology 65 246-257.
16. Segre JA, Nemhauser JL, Taylor BA, Nadeau JH & Lander ES 1995 Positional cloning of the nude locus: genetic, physical, and transcription maps of the region and mutations in the mouse and rat. Genomics 28 549-559.
17. Shao X, Xue J & Van der Hoorn FA 2001 Testicular protein Spag5 has similarity to mitotic spindle protein Deepest and binds outer dense fiber protein Odf1. Molecular Reproduction and Development 59 410-416.
18. Sharpe RM, McKinnell C, Kivlin C & Fisher JS 2003 Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood. Reproduction 125 769-784.
19. Sugihara H, Hattori T & Fukuda M 1986 Immunohistochemical detection of bromodeoxyuridine in formalin-fixed tissues. Histochemistry 85 193-195.
20. Suzuki H & Suzuki K 1995 Pathophysiology and postnatal pathogenesis of hypoplastic kidney (hpk/hpk) in the male hypogonadic mutant rat (hgn/ hgn). Journal of Veterinary Medical Science 57 891-897.
21. Suzuki H & Suzuki K 1998 Rat hypoplastic kidney (hpk/hpk) induces renal anemia, hyperparathyroidism, and osteodystrophy at the end stage of renal failure. Journal of Veterinary Medical Science 60 1051-1058.
22. Suzuki H, Hakamata Y, Kamei T, Kikukawa K & Suzuki K 1992 Reproduced fertility in female homozygotes for hgn (male hypogonadism) selected by hgn-associated hypoplastic kidney. Congenital Anomalies Kyoto 32 167-178.
23. Suzuki H, Inaba M & Suzuki K 1998 Temporal and spatial distribution of alkaline phosphatase activity in male hypogonadic rat (hgn/hgn) testis during postnatal development. Journal of Veterinary Medical Science 60 671-679.
24. Suzuki H, Kokado M, Saito K, Kunieda T & Suzuki K 1999 A locus responsible for hypogonadism (hgn) is located on rat chromosome 10. Mammalian Genome 10 1106-1107.
25. Suzuki H, Fukaya S, Saito K & Suzuki K 2000 A locus responsible for osteochondrodysplasia (ocd) is located on rat chromosome 11. Mammalian Genome 11 464-465.
26. Suzuki H, Nakamiya E, Daigo K, Saito K & Suzuki K 2004a Fine mapping of the region including hypogonadism (hgn) locus on rat chromosome 10. Journal of Veterinary Medical Science 66 1151-1154.
27. Suzuki H, Yagi M, Saito K & Suzuki K 2004b Dysplastic development of seminiferous tubules and interstitial tissue in rat hypogonadic (hgn/ hgn) testes. Biology of Reproduction 71 104-116.
28. Suzuki H, Tokuriki T, Saito K, Hishida A & Suzuki K 2005 Glomerular hyperfiltration and hypertrophy in the rat hypoplastic kidney as a model of oligomeganephronic disease. Nephrology Dialysis and Transplantation 20 1362-1369.
29. Suzuki H, Tokuriki T, Kamita H, Oota C, Takasu M, Saito K & Suzuki K 2006 Age-related pathophysiological changes in rat oligomeganephronic hypoplastic kidney. Pediatric Nephrology [in press].
30. Suzuki K, Hashimoto S, Imamichi T, Uchino T & Motoyoshi S 1987 Differential diagnosis of hydronephrosis types I and II in rats by echography. Nippon Juigaku Zasshi 49 543-546.
31. Suzuki K, Hakamata Y, Hamada A, Kikukawa K & Wada MY 1988 Imamichi T: Male hypogonadism as a candidate of deficiency of postnatal testicular growth or differentiating factor(s): a new autosomal recessive mutation in the rat. Journal of Heredity 79 54-58.
32. Suzuki K, Suzuki H, Hakamata Y, Kamei K & Kikukawa K 1991 Genetic analysis and histology of hypoplastic kidneys in the male hypogonadic mutant (hgn/hgn) rat. Congenital Anomalies Kyoto 31 305-314.
33. Suzuki K, Hakamata Y, Suzuki H, Taya K & Sasamoto S 1993 Postnatal alterations of testicular morphology, testicular testosterone contents and plasma hormone levels in male hypogonadic rat (hgn/hgn). Journal of Reproduction and Development 39 333-346.
34. Toyooka Y, Tsunekawa N, Takahashi Y, Matsui Y, Satoh M & Noce T 2000 Expression and intracellular localization of mouse Vasa-homologue protein during germ cell development. Mechanism of Development 93 139-149.
35. Xue J, Tarnasky HA, Rancourt DE & Van der Hoorn FA 2002 Targeted disruption of the testicular SPAG5/deepest protein does not affect spermatogenesis or fertility. Molecular Cell Biology 22 1993-1997.
36. Yagi M, Suzuki H & Suzuki K 2006 Apoptotic Sertoli cell death in rat hypogonadic testes during early postnatal development. Asian Journal of Andrology [in press].