Cryptosporidiosis

Tropical Infectious Diseases

Volumn 2, Issue , 2006, Pages 1003-1014

  Bushen, Oluma Yoseph ^a,b   Lima, Aldo A M ^c,d   Guerrant, Richard L ^a,e  

^a UNIVERSITY OF VIRGINIA   (United States)

^b Department of Pathology   (United States)

^c Department of Pediatrics   (Brazil)

^d FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^e UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33746379279     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-443-06668-9.50093-4     Document Type: Chapter

References (147)

1. Nime FA, Burek JD, Page DL, et al. Acute enterocolitis in a human being infected with the protozoan Cryptosporidium. Gastroenterology 1976, 70(4):592-598.
2. Meisel JL, Perera DR, Meligro C, et al. Overwhelming watery diarrhea associated with a Cryptosporidium in an immunosuppressed patient. Gastroenterology 1976, 70(6):1156-1160.
3. D'Antonio RG, Winn RE, Taylor JP, et al. A waterborne outbreak of cryptosporidiosis in normal hosts. Ann Intern Med 1985, 103(6 Part 1):886-888.
4. MacKenzie WR, Hoxie NJ, Proctor ME, et al. A massive outbreak in Milwaukee of Cryptosporidium infection transmitted through the public water supply. N Engl J Med 1994, 331(3):161-167.
5. MacKenzie WR, Schell WL, Blair KA, et al. Massive outbreak of waterborne Cryptosporidium infection in Milwaukee, Wisconsin: Recurrence of illness and risk of secondary transmission. Clin Infect Dis 1995, 21(1):57-62.
6. Corso PS, Kramer MH, Blair KA, et al. Cost of illness in the 1993 waterborne Cryptosporidium outbreak, Milwaukee, Wisconsin. Emerg Infect Dis 2003, 9(4):426-431.
7. Current WL, Reese NC A comparison of endogenous development of three isolates of Cryptosporidium in suckling mice. J Protozool 1986, 33(1):98-108.
8. Awad-El-Kariem FM, Robinson HA, Petry F, et al. Differentiation between human and animal isolates of Cryptosporidium parvum using molecular and biological markers. Parasitol Res 1998, 84(4):297-301.
9. Widmer G Genetic heterogeneity and PCR detection of Cryptosporidium parvum. Adv Parasitol 1998, 40:223-239.
10. Morgan UM, Constantine CC, Forbes DA, et al. Differentiation between human and animal isolates of Cryptosporidium parvum using rDNA sequencing and direct PCR analysis. J Parasitol 1997, 83(5):825-830.
11. Patel S, Pedraza-Diaz S, McLauchlin J The identification of Cryptosporidium species and Cryptosporidium parvum directly from whole faeces by analysis of a multiplex PCR of the 18S rRNA gene and by PCR/RFLP of the Cryptosporidium outer wall protein (COWP) gene. Int J Parasitol 1999, 29(8):1241-1247.
12. Pedraza-Diaz S, Amar C, McLauchlin J The identification and characterisation of an unusual genotype of Cryptosporidium from human faeces as Cryptosporidium meleagridis. FEMS Microbiol Lett 2000, 189(2):189-194.
13. Pieniazek NJ, Bornay-Llinares FJ, Slemenda SB, et al. New Cryptosporidium genotypes in HIV-infected persons. Emerg Infect Dis 1999, 5(3):444-449.
14. Xiao L, Bern C, Limor J, et al. Identification of 5 types of Cryptosporidium parasites in children in Lima, Peru. J Infect Dis 2001, 183(3):492-497.
15. Mallon ME, MacLeod A, Wastling JM, et al. Multilocus genotyping of Cryptosporidium parvum Type 2: Population genetics and sub-structuring. Infect Genet Evol 2003, 3(3):207-218.
16. Xiao L, Fayer R, Ryan U, et al. Cryptosporidium taxonomy: Recent advances and implications for public health. Clin Microbiol Rev 2004, 17(1):72-97.
17. Katsumata T, Hosea D, Ranuh IG, et al. Short report: Possible Cryptosporidium muris infection in humans. Am J Trop Med Hyg 2000, 62(1):70-72.
18. Fayer R, Speer C, Dubey J Cryptosporidium of man and animals. General Biology of Cryptosporidium 1995, 1-29. CRC Press, Boca Raton, FL. J. Duley, C. Speer, R. Fayer (Eds.).
19. Adal K, Sterling C, Guerrnat R Cryptosporidium and related species. Infections of the Gastrointestinal Tract 1995, 1107-1128. Raven Press, New York. M. Blaser, P. Smith, J. Ravdin (Eds.).
20. LeChevallier MW, Norton WD, Lee RG Giardia and Cryptosporidium spp. in filtered drinking water supplies. Appl Environ Microbiol 1991, 57(9):2617-2621.
21. Dillingham RA, Lima AA, Guerrant RL Cryptosporidiosis: Epidemiology and impact. Microbes Infect 2002, 4(10):1059-1066.
22. DuPont HL, Chappell CL, Sterling CR, et al. The infectivity of Cryptosporidium parvum in healthy volunteers. N Engl J Med 1995, 332(13):855-859.
23. Newman RD, Zu SX, Wuhib T, et al. Household epidemiology of Cryptosporidium parvum infection in an urban community in northeast Brazil. Ann Intern Med 1994, 120(6):500-505.
24. Cordell RL, Addiss DG Cryptosporidiosis in child care settings: A review of the literature and recommendations for prevention and control. Pediatr Infect Dis J 1994, 13(4):310-317.
25. Neill MA, Rice SK, Ahmad NV, et al. Cryptosporidiosis: An unrecognized cause of diarrhea in elderly hospitalized patients. Clin Infect Dis 1996, 22(1):168-170.
26. Naumova EN, Egorov AI, Morris RD, et al. The elderly and waterborne Cryptosporidium infection: Gastroenteritis hospitalizations before and during the 1993 Milwaukee outbreak. Emerg Infect Dis 2003, 9(4):418-425.
27. Addiss DG, Pond RS, Remshak M, et al. Reduction of risk of watery diarrhea with point-of-use water filters during a massive outbreak of waterborne Cryptosporidium infection in Milwaukee, Wisconsin, 1993. Am J Trop Med Hyg 1996, 54(6):549-553.
28. Report of a workshop. MMWR Recomm Rep 1995, 44(RR-6):1-19. Assessing the public health threat associated with waterborne cryptosporidiosis.
29. Korich DG, Mead JR, Madore MS, et al. Effects of ozone, chlorine dioxide, chlorine, and monochloramine on Cryptosporidium parvum oocyst viability. Appl Environ Microbiol 1990, 56(5):1423-1428.
30. Anderson BC Moist heat inactivation of Cryptosporidium spp. Am J Public Health 1985, 75(12):1433-1434.
31. Peng MM, Xiao L, Freeman AR, et al. Genetic polymorphism among Cryptosporidium parvum isolates: Evidence of two distinct human transmission cycles. Emerg Infect Dis 1997, 3(4):567-573.
32. Sulaiman IM, Xiao L, Yang C, et al. Differentiating human from animal isolates of Cryptosporidium parvum. Emerg Infect Dis 1998, 4(4):681-685.
33. Quiroz ES, Bern C, MacArthur JR, et al. An outbreak of cryptosporidiosis linked to a foodhandler. J Infect Dis 2000, 181(2):695-700.
34. McLauchlin J, Amar C, Pedraza-Diaz S, et al. Molecular epidemiological analysis of Cryptosporidium spp. in the United Kingdom: Results of genotyping Cryptosporidium spp. in 1,705 fecal samples from humans and 105 fecal samples from livestock animals. J Clin Microbiol 2000, 38(11):3984-3990.
35. Fretz R, Svoboda P, Ryan UM, et al. Genotyping of Cryptosporidium spp. isolated from human stool samples in Switzerland. Epidemiol Infect 2003, 131(1):663-667.
36. Kuhls TL, Mosier DA, Crawford DL, et al. Seroprevalence of cryptosporidial antibodies during infancy, childhood, and adolescence. Clin Infect Dis 1994, 18(5):731-735.
37. Zu SX, Li JF, Barrett LJ, et al. Seroepidemiologic study of Cryptosporidium infection in children from rural communities of Anhui, China and Fortaleza, Brazil. Am J Trop Med Hyg 1994, 51(1):1-10.
38. Al Braiken FA, Amin A, Beeching NJ, et al. Detection of Cryptosporidium amongst diarrhoeic and asymptomatic children in Jeddah, Saudi Arabia. Ann Trop Med Parasitol 2003, 97(5):505-510.
39. Tumwine JK, Kekitiinwa A, Nabukeera N, et al. Cryptosporidium parvum in children with diarrhea in Mulago Hospital, Kampala, Uganda. Am J Trop Med Hyg 2003, 68(6):710-715.
40. Nunez FA, Gonzalez OM, Gonzalez I, et al. Intestinal coccidia in Cuban pediatric patients with diarrhea. Mem Inst Oswaldo Cruz 2003, 98(4):539-542.
41. Gambhir IS, Jaiswal JP, Nath G Significance of Cryptosporidium as an aetiology of acute infectious diarrhoea in elderly Indians. Trop Med Int Health 2003, 8(5):415-419.
42. Menon BS, Abdullah S, Mahamud F, et al. Low prevalence of Cryptosporidium parvum in hospitalized children in Kota Bharu, Malaysia. Southeast Asian J Trop Med Public Health 2001, 32(2):319-322.
43. Newman RD, Sears CL, Moore SR, et al. Longitudinal study of Cryptosporidium infection in children in northeastern Brazil. J Infect Dis 1999, 180(1):167-175.
44. Iqbal J, Munir MA, Khan MA Cryptosporidium infection in young children with diarrhea in Rawalpindi, Pakistan. Am J Trop Med Hyg 1999, 60(5):868-870.
45. Akyon Y, Erguven S, Arikan S, et al. Cryptosporidium parvum prevalence in a group of Turkish children. Turk J Pediatr 1999, 41(2):189-196.
46. Katsumata T, Hosea D, Wasito EB, et al. Cryptosporidiosis in Indonesia: A hospital-based study and a community-based survey. Am J Trop Med Hyg 1998, 59(4):628-632.
47. Esteban JG, Aguirre C, Flores A, et al. High Cryptosporidium prevalences in healthy Aymara children from the northern Bolivian Altiplano. Am J Trop Med Hyg 1998, 58(1):50-55.
48. Nacro B, Bonkoungou P, Nagalo K, et al. [Clinical profile of cryptosporidiosis in a pediatric hospital environment in Burkina Faso]. Med Trop (Mars) 1998, 58(1):47-50.
49. Okafor JI, Okunji PO Prevalence of Cryptosporidium oocysts in faecal samples of some school children in Enugu State, Nigeria. J Commun Dis 1996, 28(1):49-55.
50. Nimri LF, Hijazi SS Cryptosporidium. A cause of gastroenteritis in preschool children in Jordan. J Clin Gastroenterol 1994, 19(4):288-291.
51. Adam AA, Hassan HS, Shears P, et al. Cryptosporidium in Khartoum, Sudan. East Afr Med J 1994, 71(11):745-746.
52. Adegbola RA, Demba E, De Veer G, et al. Cryptosporidium infection in Gambian children less than 5 years of age. J Trop Med Hyg 1994, 97(2):103-107.
53. Chacin-Bonilla L, Bonilla MC, Soto-Torres L, et al. Cryptosporidium parvum in children with diarrhea in Zulia State, Venezuela. Am J Trop Med Hyg 1997, 56(4):365-369.
54. Wang KX, Li CP, Wang J, et al. Epidemiological survey of cryptosporidiosis in Anhui Province China. World J Gastroenterol 2002, 8(2):371-374.
55. Jelinek T, Lotze M, Eichenlaub S, et al. Prevalence of infection with Cryptosporidium parvum and Cyclospora cayetanensis among international travellers. Gut 1997, 41(6):801-804.
56. Lederer W, Allerberger F, Dierich MP [ Cryptosporidia associated gastroenteritis: Epidemiologic study of children in Tyrol and Vorarlberg. Wien Klin Wochenschr 1996, 108(20):649-653.
57. Molbak K, Aaby P, Hojlyng N, et al. Risk factors for Cryptosporidium diarrhea in early childhood: A case-control study from Guinea-Bissau, West Africa. Am J Epidemiol 1994, 139(7):734-740.
58. Kirkpatrick BD, Daniels MM, Jean SS, et al. Cryptosporidiosis stimulates an inflammatory intestinal response in malnourished Haitian children. J Infect Dis 2002, 186(1):94-101.
59. Sterling CR, Gilman RH, Sinclair NA, et al. The role of breast milk in protecting urban Peruvian children against cryptosporidiosis. J Protozool 1991, 38(6):23S-25S.
60. Wuhib T, Silva TM, Newman RD, et al. Cryptosporidial and microsporidial infections in human immunodeficiency virus-infected patients in northeastern Brazil. J Infect Dis 1994, 170(2):494-497.
61. Tanyuksel M, Gun H, Doganci L Prevalence of Cryptosporidium spp. in patients with neoplasia and diarrhea. Scand J Infect Dis 1995, 27(1):69-70.
62. Arikan S, Erguven S, Akyon Y, et al. Cryptosporidiosis in immunocompromised patients in a Turkish university hospital. Acta Microbiol Immunol Hung 1999, 46(1):33-40.
63. Cegielski JP, Ortega YR, McKee S, et al. Cryptosporidium, enterocytozoon, and Cyclospora infections in pediatric and adult patients with diarrhea in Tanzania. Clin Infect Dis 1999, 28(2):314-321.
64. Cranendonk RJ, Kodde CJ, Chipeta D, et al. Cryptosporidium parvum and Isospora belli infections among patients with and without diarrhoea. East Afr Med J 2003, 80(8):398-401.
65. Goldstein ST, Juranek DD, Ravenholt O, et al. Cryptosporidiosis: An outbreak associated with drinking water despite state-of-the-art water treatment. Ann Intern Med 1996, 124(5):459-468.
66. Vakil NB, Schwartz SM, Buggy BP, et al. Biliary cryptosporidiosis in HIV-infected people after the waterborne outbreak of cryptosporidiosis in Milwaukee. N Engl J Med 1996, 334(1):19-23.
67. Lengerich EJ, Addiss DG, Marx JJ, et al. Increased exposure to Cryptosporidia among dairy farmers in Wisconsin. J Infect Dis 1993, 167(5):1252-1255.
68. Brookhart MA, Hubbard AE, van der Laan MJ, et al. Statistical estimation of parameters in a disease transmission model: Analysis of a Cryptosporidium outbreak. Stat Med 2002, 21(23):3627-3638.
69. Steiner TS, Thielman NM, Guerrant RL Protozoal agents: What are the dangers for the public water supply?. Annu Rev Med 1997, 48:329-340.
70. Tumwine JK, Kekitiinwa A, Nabukeera N, et al. Cryptosporidium parvum in children with diarrhea in Mulago Hospital, Kampala, Uganda. Am J Trop Med Hyg 2003, 68(6):710-715.
71. Checkley W, Gilman RH, Epstein LD, et al. Asymptomatic and symptomatic cryptosporidiosis: Their acute effect on weight gain in Peruvian children. Am J Epidemiol 1997, 145(2):156-163.
72. Checkley W, Epstein LD, Gilman RH, et al. Effects of Cryptosporidium parvum infection in Peruvian children: Growth faltering and subsequent catch-up growth. Am J Epidemiol 1998, 148(5):497-506.
73. Guerrant DI, Moore SR, Lima AA, et al. Association of early childhood diarrhea and cryptosporidiosis with impaired physical fitness and cognitive function four-seven years later in a poor urban community in northeast Brazil. Am J Trop Med Hyg 1999, 61(5):707-713.
74. Pettoello-Mantovani M, Di Martino L, Dettori G, et al. Asymptomatic carriage of intestinal Cryptosporidium in immunocompetent and immunodeficient children: A prospective study. Pediatr Infect Dis J 1995, 14(12):1042-1047.
75. Blanshard C, Jackson AM, Shanson DC, et al. Cryptosporidiosis in HIV-seropositive patients. Q J Med 1992, 85(307-308):813-823.
76. McGowan I, Hawkins AS, Weller IV The natural history of cryptosporidial diarrhoea in HIV-infected patients. AIDS 1993, 7(3):349-354.
77. Flanigan T, Whalen C, Turner J, et al. Cryptosporidium infection and CD4 counts. Ann Intern Med 1992, 116(10):840-842.
78. Lopez-Velez R, Tarazona R, Garcia CA, et al. Intestinal and extraintestinal cryptosporidiosis in AIDS patients. Eur J Clin Microbiol Infect Dis 1995, 14(8):677-681.
79. Davis JJ, Heyman MB Cryptosporidiosis and sinusitis in an immunodeficient adolescent. J Infect Dis 1988, 158(3):649.
80. Modigliani R, Bories C, Le Charpentier Y, et al. Diarrhoea and malabsorption in acquired immune deficiency syndrome: A study of four cases with special emphasis on opportunistic protozoan infestations. Gut 1985, 26(2):179-187.
81. Lima AA, Silva TM, Gifoni AM, et al. Mucosal injury and disruption of intestinal barrier function in HIV-infected individuals with and without diarrhea and cryptosporidiosis in northeast Brazil. Am J Gastroenterol 1997, 92(10):1861-1866.
82. Goodgame RW, Kimball K, Ou CN, et al. Intestinal function and injury in acquired immunodeficiency syndrome-related cryptosporidiosis. Gastroenterology 1995, 108(4):1075-1082.
83. Adams RB, Guerrant RL, Zu S, et al. Cryptosporidium parvum infection of intestinal epithelium: Morphologic and functional studies in an in vitro model. J Infect Dis 1994, 169(1):170-177.
84. Agnew DG, Lima AA, Newman RD, et al. Cryptosporidiosis in northeastern Brazilian children: Association with increased diarrhea morbidity. J Infect Dis 1998, 177(3):754-760.
85. Argenzio RA, Rhoads JM, Armstrong M, et al. Glutamine stimulates prostaglandin-sensitive Na(+)-H+ exchange in experimental porcine cryptosporidiosis. Gastroenterology 1994, 106(6):1418-1428.
86. Carneiro-Filho BA, Bushen OY, Brito GA, et al. Glutamine analogues as adjunctive therapy for infectious diarrhea. Curr Infect Dis Rep 2003, 5(2):114-119.
87. Sears CL, Guerrant RL Cryptosporidiosis: The complexity of intestinal pathophysiology. Gastroenterology 1994, 106(1):252-254.
88. Guarino A, Canani RB, Pozio E, et al. Enterotoxic effect of stool supernatant of Cryptosporidium-infected calves on human jejunum. Gastroenterology 1994, 106(1):28-34.
89. Guarino A, Canani RB, Casola A, et al. Human intestinal cryptosporidiosis: Secretory diarrhea and enterotoxic activity in Caco-2 cells. J Infect Dis 1995, 171(4):976-983.
90. Kandil HM, Berschneider HM, Argenzio RA Tumour necrosis factor alpha changes porcine intestinal ion transport through a paracrine mechanism involving prostaglandins. Gut 1994, 35(7):934-940.
91. Griffiths JK, Moore R, Dooley S, et al. Cryptosporidium parvum infection of Caco-2 cell monolayers induces an apical monolayer defect, selectively increases transmonolayer permeability, and causes epithelial cell death. Infect Immun 1994, 62(10):4506-4514.
92. Seydel KB, Zhang T, Champion GA, et al. Cryptosporidium parvum infection of human intestinal xenografts in SCID mice induces production of human tumor necrosis factor alpha and interleukin-8. Infect Immun 1998, 66(5):2379-2382.
93. Robinson P, Okhuysen PC, Chappell CL, et al. Substance P expression correlates with severity of diarrhea in cryptosporidiosis. J Infect Dis 2003, 188(2):290-296.
94. Benhamou Y, Kapel N, Hoang C, et al. Inefficacy of intestinal secretory immune response to Cryptosporidium in acquired immunodeficiency syndrome. Gastroenterology 1995, 108(3):627-635.
95. Taghi-Kilani R, Sekla L, Hayglass KT The role of humoral immunity in Cryptosporidium spp. infection. Studies with B cell-depleted mice. J Immunol 1990, 145(5):1571-1576.
96. Cozon G, Biron F, Jeannin M, et al. Secretory IgA antibodies to Cryptosporidium parvum in AIDS patients with chronic cryptosporidiosis. J Infect Dis 1994, 169(3):696-699.
97. Gomez Morales MA, Ausiello CM, Urbani F, et al. Crude extract and recombinant protein of Cryptosporidium parvum oocysts induce proliferation of human peripheral blood mononuclear cells in vitro. J Infect Dis 1995, 172(1):211-216.
98. Chen W, Harp JA, Harmsen AG Requirements for CD4+ cells and gamma interferon in resolution of established Cryptosporidium parvum infection in mice. Infect Immun 1993, 61(9):3928-3932.
99. Rehg JE Effect of interferon-gamma in experimental Cryptosporidium parvum infection. J Infect Dis 1996, 174(1):229-232.
100. Current WL, Reese NC, Ernst JV, et al. Human cryptosporidiosis in immunocompetent and immunodeficient persons. Studies of an outbreak and experimental transmission. N Engl J Med 1983, 308(21):1252-1257.
101. Lasser KH, Lewin KJ, Ryning FW Cryptosporidial enteritis in a patient with congenital hypogammaglobulinemia. Hum Pathol 1979, 10(2):234-240.
102. Murray HW, Welte K, Jacobs JL, et al. Production of and in vitro response to interleukin 2 in the acquired immunodeficiency syndrome. J Clin Invest 1985, 76(5):1959-1964.
103. Chen W, Harp JA, Harmsen AG, et al. Gamma interferon functions in resistance to Cryptosporidium parvum infection in severe combined immunodeficient mice. Infect Immun 1993, 61(8):3548-3551.
104. White AC, Robinson P, Okhuysen PC, et al. Interferon-gamma expression in jejunal biopsies in experimental human cryptosporidiosis correlates with prior sensitization and control of oocyst excretion. J Infect Dis 2000, 181(2):701-709.
105. Gomez Morales MA, Ausiello CM, Guarino A, et al. Severe, protracted intestinal cryptosporidiosis associated with interferon gamma deficiency: Pediatric case report. Clin Infect Dis 1996, 22(5):848-850.
106. Robinson P, Okhuysen PC, Chappell CL, et al. Expression of IL-15 and IL-4 in IFN-gamma-independent control of experimental human Cryptosporidium parvum infection. Cytokine 2001, 15(1):39-46.
107. Robinson P, Okhuysen PC, Chappell CL, et al. Expression of tumor necrosis factor alpha and interleukin 1 beta in jejuna of volunteers after experimental challenge with Cryptosporidium parvum correlates with exposure but not with symptoms. Infect Immun 2001, 69(2):1172-1174.
108. Alcantara CS, Yang CH, Steiner TS, et al. Interleukin-8, tumor necrosis factor-alpha, and lactoferrin in immunocompetent hosts with experimental and Brazilian children with acquired cryptosporidiosis. Am J Trop Med Hyg 2003, 68(3):325-328.
109. Schneiderman DJ, Cello JP, Laing FC Papillary stenosis and sclerosing cholangitis in the acquired immunodeficiency syndrome. Ann Intern Med 1987, 106(4):546-549.
110. Goodgame RW, Genta RM, White AC, et al. Intensity of infection in AIDS-associated cryptosporidiosis. J Infect Dis 1993, 167(3):704-709.
111. Chappell CL, Okhuysen PC, Sterling CR, et al. Cryptosporidium parvum: Intensity of infection and oocyst excretion patterns in healthy volunteers. J Infect Dis 1996, 173(1):232-236.
112. Garcia LS, Shimizu RY Evaluation of nine immunoassay kits (enzyme immunoassay and direct fluorescence) for detection of Giardia lamblia and Cryptosporidium parvum in human fecal specimens. J Clin Microbiol 1997, 35(6):1526-1529.
113. Alles AJ, Waldron MA, Sierra LS, et al. Prospective comparison of direct immunofluorescence and conventional staining methods for detection of Giardia and Cryptosporidium spp. in human fecal specimens. J Clin Microbiol 1995, 33(6):1632-1634.
114. Kehl KS, Cicirello H, Havens PL Comparison of four different methods for detection of Cryptosporidium species. J Clin Microbiol 1995, 33(2):416-418.
115. Perry JL, Matthews JS, Miller GR Parasite detection efficiencies of five stool concentration systems. J Clin Microbiol 1990, 28(6):1094-1097.
116. Zierdt WS Concentration and identification of Cryptosporidium spp. by use of a parasite concentrator. J Clin Microbiol 1984, 20(5):860-861.
117. Leng X, Mosier DA, Oberst RD Simplified method for recovery and PCR detection of Cryptosporidium DNA from bovine feces. Appl Environ Microbiol 1996, 62(2):643-647.
118. Zhu G, Marchewka MJ, Ennis JG, et al. Direct isolation of DNA from patient stools for polymerase chain reaction detection of Cryptosporidium parvum. J Infect Dis 1998, 177(5):1443-1446.
119. Sturbaum GD, Reed C, Hoover PJ, et al. Species-specific, nested PCR-restriction fragment length polymorphism detection of single Cryptosporidium parvum oocysts. Appl Environ Microbiol 2001, 67(6):2665-2668.
120. Foudraine NA, Weverling GJ, van Gool T, et al. Improvement of chronic diarrhoea in patients with advanced HIV-1 infection during potent antiretroviral therapy. AIDS 1998, 12(1):35-41.
121. Carr A, Marriott D, Field A, et al. Treatment of HIV-1-associated microsporidiosis and cryptosporidiosis with combination antiretroviral therapy. Lancet 1998, 351(9098):256-261.
122. Le MV, Bissuel F, Costagliola D, et al. Decreased prevalence of intestinal cryptosporidiosis in HIV-infected patients concomitant to the widespread use of protease inhibitors. AIDS 1998, 12(11):1395-1397.
123. Mele R, Gomez Morales MA, Tosini F, et al. Indinavir reduces Cryptosporidium parvum infection in both in vitro and in vivo models. Int J Parasitol 2003, 33(7):757-764.
124. White AC, Chappell CL, Hayat CS, et al. Paromomycin for cryptosporidiosis in AIDS: A prospective, double-blind trial. J Infect Dis 1994, 170(2):419-424.
125. Scaglia M, Atzori C, Marchetti G, et al. Effectiveness of aminosidine (paromomycin) sulfate in chronic Cryptosporidium diarrhea in AIDS patients: An open, uncontrolled, prospective clinical trial. J Infect Dis 1994, 170(5):1349-1350.
126. Hewitt RG, Yiannoutsos CT, Higgs ES, et al. Paromomycin: No more effective than placebo for treatment of cryptosporidiosis in patients with advanced human immunodeficiency virus infection. AIDS Clinical Trial Group. Clin Infect Dis 2000, 31(4):1084-1092.
127. Rossignol JF, Ayoub A, Ayers MS Treatment of diarrhea caused by Cryptosporidium parvum: A prospective randomized, double-blind, placebo-controlled study of Nitazoxanide. J Infect Dis 2001, 184(1):103-106.
128. Amadi B, Mwiya M, Musuku J, et al. Effect of nitazoxanide on morbidity and mortality in Zambian children with cryptosporidiosis: A randomised controlled trial. Lancet 2002, 360(9343):1375-1380.
129. Soave R, Havlir D, Lancaster D: Azithromycin therapy of AIDS-related cryptosporidial diarrhea: A multi-center, placebo-controlled, double-blind study. Programs and Abstracts of the 33rd Interscience Conference on Antimicrobial Agents and Chemotherapy, New Orleans, LA, October 17, 1993.
130. Blanshard C, Shanson DC, Gazzard BG Pilot studies of azithromycin, letrazuril and paromomycin in the treatment of cryptosporidiosis. Int J STD AIDS 1997, 8(2):124-129.
131. Smith NH, Cron S, Valdez LM, et al. Combination drug therapy for cryptosporidiosis in AIDS. J Infect Dis 1998, 178(3):900-903.
132. Loeb M, Walach C, Phillips J, et al. Treatment with letrazuril of refractory cryptosporidial diarrhea complicating AIDS. J Acquir Immune Defic Syndr Hum Retrovirol 1995, 10(1):48-53.
133. Harris M, Deutsch G, MacLean JD, et al. A phase I study of letrazuril in AIDS-related cryptosporidiosis. AIDS 1994, 8(8):1109-1113.
134. Saez-Llorens X, Odio CM, Umana MA, et al. Spiramycin vs. placebo for treatment of acute diarrhea caused by Cryptosporidium. Pediatr Infect Dis J 1989, 8(3):136-140.
135. Shield J, Melville C, Novelli V, et al. Bovine colostrum immunoglobulin concentrate for cryptosporidiosis in AIDS. Arch Dis Child 1993, 69(4):451-453.
136. Ungar BL, Ward DJ, Fayer R, et al. Cessation of Cryptosporidium-associated diarrhea in an acquired immunodeficiency syndrome patient after treatment with hyperimmune bovine colostrum. Gastroenterology 1990, 98(2):486-489.
137. Simon DM, Cello JP, Valenzuela J, et al. Multicenter trial of octreotide in patients with refractory acquired immunodeficiency syndrome-associated diarrhea. Gastroenterology 1995, 108(6):1753-1760.
138. Garcia CD, Ramos JJ, Guzman G, et al. Octreotide therapy of large-volume refractory AIDS-associated diarrhea: A randomized controlled trial. AIDS 1994, 8(11):1563-1567.
139. Liberti A, Bisogno A, Izzo E Octreotide treatment in secretory and cyrptosporidial diarrhea in patients with acquired immunodeficiency syndrome (AIDS): Clinical evaluation. J Chemother 1992, 4(5):303-305.
140. Kreinik G, Burstein O, Landor M, et al. Successful management of intractable cryptosporidial diarrhea with intravenous octreotide, a somatostatin analogue. AIDS 1991, 5(6):765-767.
141. Girard PM, Goldschmidt E, Vittecoq D, et al. Vapreotide, a somatostatin analogue, in cryptosporidiosis and other AIDS-related diarrhoeal diseases. AIDS 1992, 6(7):715-718.
142. Assessment of inadequately filtered public drinking water-Washington, D.C., December 1993. MMWR 1994, 43(36):661-669.
143. Owens JH, Miltner RJ, Schaefer FW, et al. Pilot-scale ozone inactivation of Cryptosporidium. J Eukaryot Microbiol 1994, 41(5):56S-57S.
144. Harp JA, Goff JP Protection of calves with a vaccine against Cryptosporidium parvum. J Parasitol 1995, 81(1):54-57.
145. Okhuysen PC, Chappell CL, Sterling CR, et al. Susceptibility and serologic response of healthy adults to reinfection with Cryptosporidium parvum. Infect Immun 1998, 66(2):441-443.
146. Bushen OY, Davenport JA, Lima AB, et al. Diarrhea and reduced levels of antiretroviral drugs improvement with glutamine or alanylglutamine in a randomized controlled trail in northeast Brazil. Clin Infect Dis 2004, 38(12):1764-1770.
147. Moling O, Avi A, Rimenti G, Mian P Glutamine supplementation for patients with severe cryptosporidiosis. Clin Infect Dis 2005, 40(5):773-774.