Perfluorous solid-phase organic synthesis (PF-SPOS) and IRORI technology for combinatorial chemistry

QSAR and Combinatorial Science

Volumn 25, Issue 7, 2006, Pages 598-604

  Ortega, Alberto ^a   Erra, Montserrat ^a   Navarro, Eloísa ^a   Roberts, Richard S ^a   Fernández Forner, Dolors ^b  

^a Almirall Research Centre ^*  (Spain)

^b PROUS SCIENCE   (Spain)

Author keywords

IRORI; Libraries; Perfluorodecalin; Perfluorous solvents; Solid phase synthesis

Indexed keywords

BIOCHIPS; LIBRARIES; SYNTHESIS (CHEMICAL);

COMBINATORIAL CHEMISTRY; CONDITION; IRORI; ITS APPLICATIONS; PERFLUORODECALIN; PERFLUOROUS SOLVENT; QUINAZOLINONES; SOLID PHASE SYNTHESIS; SOLID-PHASE ORGANIC SYNTHESIS; TECHNOLOGY APPLICATION;

SOLVENTS;

3,4 DIHYDRO 2(1H) QUINAZOLINONE DERIVATIVE; DIHYDROQUINAZOLINE DERIVATIVE; PERFLUORO COMPOUND; QUINAZOLINE DERIVATIVE; QUINAZOLINONE DERIVATIVE; SOLVENT; UNCLASSIFIED DRUG;

ARTICLE; BIOREACTOR; COMBINATORIAL CHEMISTRY; COMPARATIVE STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; PRIORITY JOURNAL; SOLID PHASE SYNTHESIS;

EID: 33746370387     PISSN: 1611020X     EISSN: 16110218     Source Type: Journal    
DOI: 10.1002/qsar.200520188     Document Type: Article

References (17)

1. Some of the papers found in the literature are: a) T. F. Herpin, K. G. Van Kirk, J. M. Salvino, S. T. Yu, R. F. Labaudiniere, J. Comb. Chem. 2000, 2, 513-521.
2. b) A. D. Morley, Tetrahedron Lett. 2000, 41, 7405-7408;
3. C. Migihashi, F. Sato, J. Heterocycl. Chem. 2003, 40, 143-147;
4. G. Guo, E. A. Arvanitis, R. S. Pottorf, M. R. Player, J. Comb. Chem. 2003, 5, 408-413.
5. K. E. Myers, K. Kumar, J. Am. Chem. Soc. 2000, 122, 12025-12026.
6. J. R. Morphy, Z. Rankovic, M. York, Tetrahedron. Lett. 2001, 42, 7509-7511.
7. a) I. T. Horvath, Acc. Chem. Res. 1998, 31, 641-650.
8. b) A. P. Dobbs, M. R. Kimberley, J. Fluorine Chem. 2002, 118, 3-17.
9. J. A. Gladysz, D. P. Curran, I. T. Horvath (Eds.), Handbook of Flourous Chemistry Wiley-VCH, Weinheim, Germany 2004.
10. I. T. Horvath, J. Rabai, Science 1994, 266, 72.
11. R. S. Roberts, J. Comb. Chem. 2005, 7, 21-32.
12. a) Q. Sun, X. Zhou, D. J. Kyle, Tetrahedron. Lett. 2001, 42, 4119-4121.
13. J. Zhang, J. Barker, B. Lou, Hossain Saneii, Tetrahedron. Lett. 2001, 42, 8405-8408.
14. a) J. R. Morphy, Z. Rankovic, M. York, Tetrahedron 2003, 59, 2137-2145.
15. b) J. R. Morphy, Z. Rankovic, M. York, Tetrahedron. Lett. 2002, 43, 6413-6415.
16. M. Shi, S. C. Cui, New J. Chem. 2004, 28, 1286-1288.
17. IRORI User's Guide (www.irori.com).