Elevated levels of alkanals, alkenals and 4-HO-alkenals in plasma of hemodialysis patients

American Journal of Nephrology

Volumn 26, Issue 3, 2006, Pages 299-303

  Alhamdani, Mohamed Saiel Saeed ^a   Al Kassir, Abdul Hameed A M ^a,b   Jaleel, Nidham A ^a,b   Hmood, Ammar Muola ^c   Ali, Huda Mohammed ^a,c  

^a MUSTANSIRIYAH UNIVERSITY   (Iraq)

^b BAGHDAD TEACHING HOSPITAL   (Iraq)

^c Iraqi Organization of Science and Technology   (Iraq)

Author keywords

4 HO alkenals; Aldehydes; Alkanals; Alkenals; Hemodialysis; Protein modification

Indexed keywords

2 HEPTENAL; 2 HEXENAL; 2 NONENAL; 2 OCTENAL; 4 DECENAL; 4 HYDROXYDECENAL; 4 HYDROXYHEXENAL; 4 HYDROXYNONENAL; 4 HYDROXYOCTENAL; ADVANCED GLYCATION END PRODUCT; ALDEHYDE; ALKANE DERIVATIVE; ALKENE DERIVATIVE; AMIDE; AMINO ACID; AMYLOID; BIOLOGICAL MARKER; CARBONYL DERIVATIVE; DECANAL; DEDECANAL; HEPTYL ALDEHYDE; HEXANAL; NONANAL; OCTANAL; PROTEIN; THIOL; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BLOOD LEVEL; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HEMODIALYSIS PATIENT; HUMAN; LIPID PEROXIDATION; MALE; MEASUREMENT; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN MODIFICATION; TOXICOKINETICS; UREMIA;

ALKANES; ALKENES; BIOLOGICAL MARKERS; FEMALE; HUMANS; MALE; MIDDLE AGED; RENAL DIALYSIS; UREMIA;

EID: 33746363497     PISSN: 02508095     EISSN: None     Source Type: Journal    
DOI: 10.1159/000094305     Document Type: Article

References (13)

1. London GM, Drueke TB: Atherosclerosis and arteriosclerosis in chronic renal failure. Kidney Int 1997;51:1678-1695.
2. Zoccali C, Mallamaci F, Tripepi G: AGEs and carbonyl stress: potential pathogenetic factors of long-term uraemic complications. Nephrol Dial Transplant 2000;15(suppl 2):7-11.
3. Esterbauer H, Schaur JS, Zollner H: Chemistry and biochemistry of 4-hydroxynonenal, malondialdehyde and related aldehydes. Free Radic Biol Med 1991;11:81-128.
4. Miyata T, Wada Y, Cai Z, Iida Y, Horie K, Maeda K, van Ypersele de Strihou C: Implication of an increased oxidative stress in the formation of advanced glycation end products inpatients with end-stage renal failure. Kidney Int 1997;51:1170-1181.
5. Requena JR, Fu MX, Ahmed MU, Jenkins AJ, Lyons TJ, Thorpe SR: Lipoxidation products as biomarkers of oxidative damage to proteins during lipid peroxidation reactions. Nephrol Dial Transplant 1996;11(suppl 5):48-53.
6. Luo XP, Yazdanpanah M, Bhooi N, Lehotay DC: Determination of aldehydes and other lipid peroxidation products in biological samples by gas chromatography-mass spectrometry. Anal Biochem 1995;228:294-298.
7. Levine RL, Garland D, Oliver CN, Amici A, Climent I, Lenz AG, Ahn BW, Shantiel S, Stadtman ER: Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 1990;186:464-478.
8. Davies KJA, Delsignore ME, Lin SW: protein damage and degradation by oxygen radicals. II. Modification of amino acids. J Biol Chem 1987;262:9902-9907.
9. Ellman GL: Tissue sulfhydryl groups. Arch Biochem Biophys 1959;82:70-77.
10. Naiki H, Higuchi K, Hosokawa M, Takeda T: Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1. Anal Biochem 1989;177:244-249.
11. Kaneko T, Kaji K, Matsuo M: Cytotoxicities of a linoleic acid hydroperoxide and its related aliphatic aldehydes toward cultured human umbilical vein endothelial cells. Chem Biol Interact 1988;67:295-304.
12. Galli F, Rovidati S, Benedetti S, Buoncristiani U, Covarelli C, Floridi A, Canestrari F: Overexpression of erythrocyte glutathione S-transferase in uremia and dialysis. Clin Chem 1999;45:1781-1788.
13. Miyata T, Ueda Y, Saito A, Kurokawa K: 'Carbonyl stress' and dialysis-related amyloidosis. Nephrol Dial Transplant 2000;15(suppl 1):25-28.