Serotype K1 capsule, rather than magA per se, is really the virulence factor in Klebsiella pneumoniae strains that cause primary pyogenic liver abscess [3]

Journal of Infectious Diseases

Volumn 194, Issue 3, 2006, Pages 403-404

  Yeh, Kuo Ming ^a,b   Chang, Feng Yee ^a   Fung, Chang Phone ^c   Lin, Jung Chung ^a   Siu, L K ^b,d  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

VIRULENCE FACTOR;

BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CPS GENE; HUMAN; KLEBSIELLA PNEUMONIAE; LETTER; MAGA GENE; PRIORITY JOURNAL; PYOGENIC LIVER ABSCESS; SEROTYPE;

BACTERIAL CAPSULES; BACTERIAL PROTEINS; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; LIVER ABSCESS, PYOGENIC; VIRULENCE FACTORS;

EID: 33746353108     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/505153     Document Type: Letter

References (8)

1. Chuang YP, Fang CT, Lai SY, Chang SC, Wang JT. Genetic determinants of capsular serotype K1 of Klebsiella pneumoniae causing primary pyogenic liver abscess. J Infect Dis 2006; 193: 645-54.
2. Yeh KM, Chang FY, Fung CP, Lin JC, Siu LK. magA is not a specific virulence gene for Klebsiella pneumoniae strains causing liver abscess but is part of the capsular polysaccharide gene cluster of K. pneumoniae serotype K1. J Med Microbiol 2006; 55(Pt 6):803-4.
3. Fang CT, Chuang YP, Shun CT, Chang SC, Wang JT. A novel virulence gene in Klebsiella pneumoniae strains causing primary liver abscess and septic metastatic complications. J Exp Med 2004; 199:697-705.
4. Fung CP, Chang FY, Lee SC, et al. A global emerging disease of Klebsiella pneumoniae liver abscess: is serotype K1 an important factor for complicated endophthalmitis? Gut 2002; 50: 420-4.
5. Strove C, Bojer M, Nielsen EM, Hansen DS, Krogfelt KA, Investigation of the putative virulence gene magA in a worldwide collection of 495 Klebsiella isolates: magA is restricted to the gene cluster of Klebsiella pneumoniae capsule serotype K1. J Med Microbiol 2005; 54:1111-3.
6. Tsay RW, Siu LK, Fung CP, Chang FY. Characteristics of bacteremia between community-acquired and nosocomial Klebsiella pneumoniae infection: risk factor for mortality and the impact of capsular serotypes as a herald for community-acquired infection. Arch Intern Med 2002; 162:1021-7.
7. Cheng HP, Chang FY, Fung CP, Siu LK. Klebsiella pneumoniae liver abscess in Taiwan is not caused by a clonal spread strain. J Microbiol Immunol Infect 2002; 35:85-8.
8. Lee CH, Leu HS, Wu TS, Su LH, Liu JW. Risk factors for spontaneous rupture of liver abscess caused by Klebsiella pneumoniae. Diagn Microbiol Infect Dis 2005; 52:79-84.