Langerhans cell histiocytosis: A clinical update

Histiocytic Disorders of Children and Adults

Volumn , Issue , 2005, Pages 95-129

  Donadieu, Jean ^a   Egeler, R Maarten ^b   Pritchard, Jon ^c  

^a ARMAND TROUSSEAU HOSPITAL   (France)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33746311542     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1017/CBO9780511545252.007     Document Type: Chapter

References (100)

1. Al Asiri, R., Al Shahed, M. and Wali, S. (2000). Histiocytosis X and Caroli’s disease. Saudi Med J, 21, 306-307.
2. Annels, N.E., da Costa, C.E.T., Prins, F.A., et al. (2003). Aberrant chemokine receptor expression and chemokine production by Langerhans cells underlies the pathogenesis of Langerhans cell histiocytosis. J Exp Med, 197, 1385-1390.
3. Arico, M. (2004). Langerhans cell histiocytosis in adults: more questions than answers? Eur J Cancer, 40(10), 1467-1473.
4. Arico, M., Haupt, R., Russotto, V.S., et al. (2001). Langerhans cell histiocytosis in 2 generations: a new family and review of the literature. Med Pediatr Oncol, 36, 314-316.
5. Arico, M., Girschikofsky, M., Genereau, T., et al. (2003). Langerhans cell histiocytosis in adults. Report from the International Registry of the Histiocyte Society. Eur J Cancer, 39,2341-2348.
6. Barthez, M.A., Araujo, E. and Donadieu, J. (2000). Langerhans cell histiocytosis and the central nervous system in childhood: evolution and prognostic factors. Results of a collaborative study. J Child Neurol, 15, 150-156.
7. Bernstrand, C., Cederlund, K., Ahstrom, L., et al. (2000). Smoking preceded pulmonary involvement in adults with Langerhans cell histiocytosis diagnosed in childhood. Acta Paediatr, 89, 1389-1392.
8. Bernstrand, C., Cederlund, K., Sandstedt, B., et al. (2001). Pulmonary abnormalities at long-term follow-up of patients with Langerhans cell histiocytosis. Med Pediatr Oncol, 36,459-468.
9. Berry, D.H., Gresik, M.V., Humphrey, G.B., et al. (1986). Natural history of histiocytosis X: a Pediatric Oncology Group Study. Med Pediatr Oncol, 14, 1-5.
10. Bollini, G., Jouve, J.L., Gentet, J.C., et al. (1991). Bone lesions in histiocytosis X. J Pediatr Orthoped, 11,469-477.
11. Braier, J., Chantada, G., Rosso, D., et al. (1999). Langerhans cell histiocytosis: retrospective evaluation of 123 patients in a single institution. Pediatr Hematol Oncol, 16, 377-385.
12. Braier, J., Cioccca, M., Latella, A., et al. (2002). Cholestasis, sclerosing cholangitis, and liver transplantation in Langerhans cell histiocytosis. Med Pediatr Oncol, 38, 178-182.
13. Brauner, M.W., Grenier, P., Tijani, K., et al. (1997). Pulmonary Langerhans cell histiocytosis: evolution of lesions on CT scans. Radiology, 204,497-502.
14. Broadbent, V. (1986). Favourable prognostic features in histiocytosis X: bone involvement and absence of skin disease. Arch Dis Child, 61(12), 1219-1221.
15. Broadbent, V. and Pritchard, J. (1997). Diabetes insipidus associated with Langerhans celll histiocytosis: is it reversible? Med Pediatr Oncol, 28,289-293.
16. Broadbent, V., Williams, M. and Dossetor, J. (1990). Ruptured spleen as a cause of death in an infant with Langerhans cell histiocytosis (histiocytosis X). Pediatr Hematol Oncol, 7,297-299.
17. Calming, U., Bernstrand, C., Mosskin, M., etal. (2002). Brain 18-FDG PET scan in central nervous system Langerhans cell histiocytosis. J Pediatr, 141, 435-440.
18. Carlson, R.A., Hattery, R.R., O’Connell, E.J., et al. (1976). Pulmonary involvement by histiocytosis X in the pediatric age group. Mayo Clin Proc, 51, 542-547.
19. Ceci, A., de Terlizzi, M., Colella, R., et al. (1988). Etoposide in recurrent childhood Langerhans’ cell histiocytosis: an Italian cooperative study. Cancer, 62,2528-2531.
20. Chen, C.Y., Wu, M.H., Huang, S.F., et al. (2001). Langerhans’ cell histiocytosis presenting with a para-aortic lesion and heart failure. J Formos Med Assoc, 100, 127-130.
21. Chomette, G., Auriol, M., Ragot, J.P., et al. (1987). Histiocytosis X of the jaw. I. Anatomico-clinical study apropos of 61 cases. Rev Stomatol Chir Maxillofac, 88, 334-338.
22. Chu, T., D’Angio, G.J., Favara, B., et al. (1987). Histiocytosis syndromes in children. Lancet, 1, 208-209.
23. Cline, M.J. (1994). Histiocytes and histiocytosis. Blood, 84, 2840-2853.
24. Corry, A., Russell, W., McPhillips, M., et al. (2004). Comment on: Imashuku et al. Pineal dysfunction (low melatonin production) as a cause of sudden death in a long-term survivor of Langerhans cell histiocytosis? Med Pediatr Oncol 2003; 41: 151-153. Pediatr Blood Cancer, 43,93-94.
25. Cunningham, M.J., Curtin, H.D., Jaffe, R., et al. (1989). Otologic manifestations of Langerhans’ cell histiocytosis. Arch Otolaryngol Head Neck Surg, 115, 807-813.
26. Daras, C., Grayson, W., Mayet, I., et al. (1995). Langerhans’ cell histiocytosis of the eyelid. Br J Ophthalmol, 79, 91-92.
27. Dattani, M.T. (2001). Tests in paediatric endocrinology and normal values. In: Brook, C.G.D. and Handmarsh, C., eds, Endocrinology. Blackwell Science Cambridge, pp. 467-490.
28. Debray, D. (2003). Sclerosing cholangitis in children: an overview. Proceedings of the XIX Meeting of the Histiocyte Society, Philadelphia, 17.
29. Dehner, L.P. (2003). Juvenile xanthogranulomas in the first two decades of life: a clinicopatho- logic study of 174 cases with cutaneous and extracutaneous manifestations. Am J Surg Pathol, 27, 579-593.
30. Dimentberg, R.A. and Brown, K.L. (1990). Diagnostic evaluation of patients with histiocytosis X. J Pediatr Orthop, 10, 733-741.
31. Dogan, A.S., Conway, J.J., Miller, J.H., et al. (1996). Detection of bone lesions in Langerhans cell histiocytosis: complementary roles of scintigraphy and conventional radiography. J Pediatr Hematol Oncol, 18, 51-58.
32. Donadieu, J., Rolon, M.A., Pion, I., et al. (2004a). Incidence of growth hormone deficiency in pediatric-onset Langerhans cell histiocytosis: efficacy and safety of growth hormone treatment. J Clin Endocrinol Metab, 89, 604-609.
33. Donadieu, J., Rolon, M.A., Thomas, C., et al. (2004b). Endocrine involvement in pediatric-onset Langerhans’ cell histiocytosis: a population-based study. J Pediatr, 144, 350.
34. Donadieu, J., Piguet, F., Bernard, M., et al. (2004c). A new clinical score for disease activity in Langerhans cell histiocytosis. Ped Blood Cancer, 43, 770-776.
35. Dunger, D.B., Broadbent, V., Yeoman, E., et al. (1989). The frequency and natural history of diabetes insipidus in children with Langerhans-cell histiocytosis. New Engl J Med, 321, 1157-1162.
36. Duranay, M., Aribas, O.K., Erbilen, M., et al. (1996). Histiocytosis X and glomerulonephritis: a case report. Nephron, 73, 329-330.
37. Edgar, J.D., Smyth, A.E., Pritchard, J., et al. (2001). Interferon-gamma receptor deficiency mimicking Langerhans’ cell histiocytosis. JPediatr, 139(4), 600-603.
38. Egeler, R.M., Schipper, M.E. and Heymans, H.S.A. (1990). Gastrointestinal involvement in Langerhans’ cell histiocytosis (histiocytosis X): a clinical report of three cases. Eur J Pediatr, 149, 325-329.
39. Egeler, R.M., de Kraker, J. and Voute, P.A. (1993). Cytosine-arabinoside, vincristine, and prednisolone in the treatment of children with disseminated Langerhans cell histiocytosis with organ dysfunction: experience at a single institution. Med Pediatr Oncol, 21, 265-270.
40. Emile, J.F., Wechsler, J., Brousse, N., et al. (1995). Langerhans’ cell histiocytosis. Definitive diagnosis with the use of monoclonal antibody O10 on routinely paraffin-embedded samples. Am J Surg Pathol, 19, 636-641.
41. Favara, B.E., Jaffe, R. and Egeler, R.M. (2002). Macrophage activation and hemophagocytic syndrome in Langerhans’ cell histiocytosis. A report of 30 cases. Pediatr Dev Pathol, 5, 130-140.
42. Gabbay, E., Dark, J.H., Ashcroft, T., et al. (1998). Recurrence of Langerhans’ cell granulomatosis following lung transplantation. Thorax, 53, 326-327.
43. Gadner, H., Heitger, A., Grois, N., et al. (1994). Treatment strategy for disseminated Langerhans cell histiocytosis. Med Pediatr Oncol, 23, 72-80.
44. Gadner, H., Grois, N., Arico, M., et al. (2001). A randomized trial of treatment for multisystem Langerhans’ cell histiocytosis. J Pediatr, 138, 728-734.
45. Geissmann, F., Thomas, C., Emile, J.F., et al. (1996). Digestive tract involvement in Langerhans cell histiocytosis. The French Langerhans Cell Histiocytosis Study Group. J Pediatr, 129, 836-845.
46. Greenberger, J.S., Cassady, J.R., Jaffe, N., et al. (1979). Radiation therapy in patients with histiocytosis: management of diabetes insipidus and bone lesions. Int J Radiat Oncol Biol Phys, 5, 1749-1755.
47. Grois, N., Flucher-Wolfram, B., Heitger, A., et al. (1995). Diabetes insipidus in Langerhans cell histiocytosis: results from the DAL-HX 83 study. Med Pediatr Oncol, 24, 248-256.
48. Grois, N.G., Favara, B.E., Mostbeck, G.H., et al. (1998). Central nervous system disease in Langerhans cell histiocytosis. Hematol Oncol Clin North Am, 12, 287-305.
49. Grois, N., Prayer, D., Prosch, H., et al. (2004). Course of diabetes insipidus in Langerhans cell histiocytosis and clinical impact of associated magnetic resonance imaging findings in diabetes insipidus associated with Langerhans cell histiocytosis. Ped Blood Cancer, 43, 59-65.
50. Ha, S.Y., Helms, P., Fletcher, M., et al. (1992). Lung involvement in Langerhans’ cell histiocytosis: prevalence, clinical features, and outcome. Pediatrics, 89, 466-469.
51. Hamada, K., Teramoto, S., Narita, N., et al. (2000). Pulmonary veno-occlusive disease in pulmonary Langerhans’ cell granulomatosis. Eur Respir J, 15,421-423.
52. Hand, A. (1893). Polyuria and tuberculosis. Arch Pediatr, 10, 673-675
53. Hoeger, P.H., Diaz, C., Malone, M., et al. (2001). Juvenile xanthogranuloma as a sequel to Langerhans cell histiocytosis: a report of three cases. Clin Exp Dermatol, 26, 391-394.
54. Howarth, D.M., Mullan, B.P., Wiseman, G.A., et al. (1996). Bone scintigraphy evaluated in diagnosing and staging Langerhans’ cell histiocytosis and related disorders. J Nucl Med, 37, 1456-1460.
55. Howarth, D.M., Gilchrist, G.S., Mullan, B.P., et al. (1999). Langerhans cell histiocytosis. Diagnosis, natural history, management and outcome. Cancer, 85,2278-2290.
56. Kelly, K.M. and Pritchard, J. (1994). Monoclonal antibody therapy in Langerhans cell histiocytosis-feasible and reasonable? Br J Cancer, 23(Suppl), S54-S55.
57. Kilpatrick, S.E., Wenger, D.E., Gilchrist, G.S., et al. (1995). Langerhans’ cell histiocytosis (histiocytosis X) of bone. Cancer, 76, 2471-2484.
58. Klein, A., Corazza, F., Demulder, A., et al. (1999). Recurrent viral associated hemophagocytic syndrome in a child with Langerhans cell histiocytosis. J Pediatr Hematol Oncol, 21, 554-556.
59. Komp, D.M., El Mahdi, A., Starling, K.A., et al. (1980). Quality of survival in histiocytosis X: a Southwest Oncology Group study. Med Pediatr Oncol, 8, 35-40.
60. Lahey, E. (1975). Histiocytosis X - an analysis of prognostic factors. J Pediatr, 87, 184-189.
61. Laman, J.D., Leenen, P.J., Annels, N.E., et al. (2003). Langerhans-cell histiocytosis ‘insight into DC biology’. Trend Immunol, 24, 190-196.
62. Lichtenstein, L. (1953). Histiocytosis X: integration of eosinophilic granuloma of bone, Letterer-Siwe disease and Schuller-Christian disease as related manifestations of a single nosologic entity. Am Medl Assoc Arch Pathol, 56, 84-102.
63. Lieberman, P.H., Jones, C.R., Steinman, R.M., et al. (1996). Langerhans cell (eosinophilic) granulomatosis. A clinicopathologic study encompassing 50 years. Am J Surg Pathol, 20, 519-552.
64. Maghnie, M., Cosi, G., Genovese, E., et al. (2000). Central diabetes insipidus in children and young adults. New Engl J Med, 343, 998-1007.
65. McLean, T.W. and Pritchard, J. (1996). Langerhans cell histiocytosis and hypercalcemia: clinical response to indomethacin. J Pediatr Hematol Oncol, 18(3), 318-320.
66. McLelland, J., Broadbent, V., Yeomans, E., et al. (1990). Langerhans cell histiocytosis: the case for conservative therapy. Arch Dis Child, 65, 301-303.
67. Minkov, M., Grois, N., Heitger, A., et al. (2000). Treatment of multisystem Langerhans cell histiocytosis. Results of the DAL-HX 83 and DAL-HX 90 studies. Klin Padiatr, 212, 139-144.
68. Mogul, M., Hartman, G., Donaldson, S., et al. (1993). Langerhans cell histiocytosis presenting with the superior vena cava syndrome: a case report. Med Pediatr Oncol, 21,456-459.
69. Moore, A.T., Pritchard, J. and Taylor, D.S. (1985). Histiocytosis X: an ophthalmological review. Br J Ophthalmol, 69, 7-14.
70. Muwakkit, S., Gharagozloo, A., Souid, A.K., et al. (1994). The sonographic appearance of lesions of the spleen and pancreas in an infant with Langerhans’ cell histiocytosis. Pediatr Radiol, 24, 222-223.
71. Nanduri, V.R., Pritchard, J., Chong, W.K., et al. (1998). Labyrinthine involvement in Langerhans’ cell histiocytosis. Int J Pediatr Otorhinolaryngol, 46, 109-115.
72. Nanduri, V.R., Kelly, K., Malone, M., et al. (1999). Colon involvement in Langerhans’ cell histiocytosis. J Pediatr Gastroenterol Nutr, 29,462-466.
73. Nanduri, V.R., Barelle, P., Pritchard, J., et al. (2000). Growth and endocrine disorders in multisystem Langerhans cell histiocytosis. Clin Endocrinol, 53, 509-515.
74. Nanduri, V.R., Lillywhite, L., Chapman, C., et al. (2003). Cognitive outcome of long-term survivors of multisystem langerhans cell histiocytosis: a single-institution, cross-sectional study. J Clin Oncol, 21,2961-2967.
75. Nezelof, C., Frileux-Herbert, F. and Cronier-Sachot, J. (1979). Disseminated histiocytosis X. Analysis of prognostic factors based on a retrospective study of 50 cases. Cancer, 44,1824-1838.
76. Nondahl, S.R., Finlay, J.L., Farrell, P.M., et al. (1986). A case report and literature review of‘primary’ pulmonary histiocytosis X of childhood. Med Pediatr Oncol, 14, 57-62.
77. Ottaviano, F. and Finlay, J.L. (2003). Diabetes insipidus and Langerhans cell histiocytosis: a case report of reversibility with 2-chlorodeoxyadenosine. J Pediatr Hematol Oncol, 25, 575-577.
78. Papagelopoulos, P.J., Currier, B.L., Galanis, E., et al. (2002). Vertebra plana caused by primary Ewing sarcoma: case report and review of the literature. J Spinal Disord Tech, 15(3), 252-257.
79. Pinckney, L. and Parker, B.R. (1977). Myelosclerosis and myelofibrosis in treated histiocytosis-X. Am J Roentgenol, 129, 521-523.
80. Pritchard, J., Foley, P. and Wong, H. (2003). Langerhans and Langhans: what’s misleading in a name? Lancet, 362, 922.
81. Raney Jr, D.B. and D’Angio, G.J. (1989). Langerhans’ cell histiocytosis (histiocytosis X): experience at the Children’s Hospital of Philadelphia, 1970-1984. Med Pediatr Oncol, 17, 20-28.
82. Refabert, L., Rambaud, C., Mamou-Mani, T., et al. (1996). CD1a-positive cells in bronchoalveolar lavage samples from children with Langerhans cell histiocytosis. J Pediatr, 129, 913-915.
83. Rivera-Luna, R., Alter-Molchadsky, N., Cardenas-Cardos, R., et al. (1988). Langerhans cell histiocytosis in children under 2 years of age. Med Pediatr Oncol, 26, 334-343.
84. Sartoris, D.J. and Parker, B.R. (1984). Histiocytosis X: rate and pattern of resolution of osseous lesions. Radiology, 152, 679-684.
85. Sartoris, D.J. and Resnick, D. (1985). Myelofibrosis arising in treated histiocytosis X. Eur J Pediatr, 144,200-202.
86. Sheils, C. and Dover, G.J. (1989). Frequency of congenital anomalies in patients with histiocytosis X. Am J Hematol, 31, 91-95.
87. Slater, J.M. and Swarm, O.J. (1980). Eosinophilic granuloma of bone. Med Pediatr Oncol, 8, 151-164.
88. Surico, G., Muggeo, P., Muggeo, V., et al. (2000). Ear involvement in childhood Langerhans’ cell histiocytosis. Head Neck, 22, 42-47.
89. The French LCH Study Group (1996). A multicentre retrospective survey of LCH: 348 cases observed between 1983 and 1993. Arch Dis Child, 75, 17-24.
90. Titgemeyer, C., Grois, N., Minkov, M., et al. (2001). Pattern and course of single-system disease in Langerhans cell histiocytosis data from the DAL-HX 83 and 90 study. Med Pediatr Oncol, 37, 108-114.
91. Trouillas, P., Takayanagi, T., Hallett, M., et al. (1997). International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome. The Ataxia Neuropharmacology Committee of the World Federation of Neurology. J Neurol Sci, 145,205-211.
92. Tsuchiya, H., Ishibashi, F., Migita, M., et al. (1995). Perirenal mass of Langerhans cell histiocytosis. Eur J Pediatr, 154, 117-119.
93. Vassallo, R., Ryu, J.H., Schroeder, D.R., et al. (2002). Clinical outcomes of pulmonary Langerhans’- cell histiocytosis in adults. New Engl J Med, 346, 484-490.
94. Wang, K.H., Cheng, C.J., Hu, C.H., et al. (2002). Coexistence of localized Langerhans cell histiocytosis and cutaneous Rosai-Dorfman disease. Br J Dermatol, 147, 770-774.
95. Werner, K., Pritchard, J., Lappi, M., et al. (2003). Chronic papilloedema due to intra-orbital Langerhans cell histiocytosis. Med Pediatr Oncol, 41, 580-583.
96. Willis, B., Ablin, A., Weinberg, V., et al. (1996). Disease course and late sequelae of Langerhans’ cell histiocytosis: a 25 year experience at the University of Southern California, San Francisco. J Clin Oncol, 14, 2073-2082.
97. Willman, C.L., Busque, L., Griffiths, B.B., et al. (1994). Langerhans cell histiocytosis - a clonal proliferation of Langerhans cells. New Engl J Med, 331, 154-160.
98. Witters, G., Baert, L., D’Hoedt, M., et al. (1991). Eosinophilic granuloma of bladder. Urology, 37, 72-74.
99. Yu, C.P., Tseng, H.H. and Tu, Y.C. (1990). Congenital Letterer-Siwe disease with intrauterine fetal death: a case report and review of the literature. J Formos Med Assoc, 89, 806-810.
100. Yu, R.C., Attra, A., Quinn, C.M., et al. (1993). Multisystem Langerhans’ cell histiocytosis with pancreatic involvement. Gut, 34, 570-572.