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Volumn 153, Issue , 2006, Pages 47-55

Chapter 2: Synaptic plasticity mediating leptin's effect on metabolism

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; PROOPIOMELANOCORTIN;

EID: 33746294475     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(06)53002-X     Document Type: Review
Times cited : (11)

References (50)
  • 1
    • 0032702290 scopus 로고    scopus 로고
    • Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene
    • Acampora D., Postiglione M.P., Avantaggiato V., Di Bonito M., Vaccarino F.M., Michaud J., and Simeone A. Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene. Genes Dev. 13 (1999) 2787-2800
    • (1999) Genes Dev. , vol.13 , pp. 2787-2800
    • Acampora, D.1    Postiglione, M.P.2    Avantaggiato, V.3    Di Bonito, M.4    Vaccarino, F.M.5    Michaud, J.6    Simeone, A.7
  • 2
    • 0036325531 scopus 로고    scopus 로고
    • Genetic approaches to studying energy balance: perception and integration
    • Barsh G.S., and Schwartz M.W. Genetic approaches to studying energy balance: perception and integration. Nat. Rev. Genet. 3 (2002) 589-600
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 589-600
    • Barsh, G.S.1    Schwartz, M.W.2
  • 3
    • 0032998652 scopus 로고    scopus 로고
    • Leptin receptor mRNA identifies a subpopulation of neuropeptide Y neurons activated by fasting in rat hypothalamus
    • Baskin D.G., Breininger J.F., and Schwartz M.W. Leptin receptor mRNA identifies a subpopulation of neuropeptide Y neurons activated by fasting in rat hypothalamus. Diabetes 48 (1999) 828-833
    • (1999) Diabetes , vol.48 , pp. 828-833
    • Baskin, D.G.1    Breininger, J.F.2    Schwartz, M.W.3
  • 5
    • 0037464510 scopus 로고    scopus 로고
    • Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults
    • Calle E.E., Rodriguez C., Walker-Thurmond K., and Thun M.J. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N. Engl. J. Med. 348 (2003) 1625-1638
    • (2003) N. Engl. J. Med. , vol.348 , pp. 1625-1638
    • Calle, E.E.1    Rodriguez, C.2    Walker-Thurmond, K.3    Thun, M.J.4
  • 6
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield L.A., Smith F.J., Guisez Y., Devos R., and Burn P. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269 (1995) 546-549
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Guisez, Y.3    Devos, R.4    Burn, P.5
  • 7
    • 8844247986 scopus 로고    scopus 로고
    • CPG2: a brain- and synapse-specific protein that regulates the endocytosis of glutamate receptors
    • Cottrell J.R., Borok E., Horvath T.L., and Nedivi E. CPG2: a brain- and synapse-specific protein that regulates the endocytosis of glutamate receptors. Neuron 44 (2004) 677-690
    • (2004) Neuron , vol.44 , pp. 677-690
    • Cottrell, J.R.1    Borok, E.2    Horvath, T.L.3    Nedivi, E.4
  • 8
    • 0041920735 scopus 로고    scopus 로고
    • Fasting activates the nonhuman primate hypocretin (orexin) system and its postsynaptic targets
    • Diano S., Horvath B., Urbanski H.F., Sotonyi P., and Horvath T.L. Fasting activates the nonhuman primate hypocretin (orexin) system and its postsynaptic targets. Endocrinology 144 (2003) 3774-3778
    • (2003) Endocrinology , vol.144 , pp. 3774-3778
    • Diano, S.1    Horvath, B.2    Urbanski, H.F.3    Sotonyi, P.4    Horvath, T.L.5
  • 9
    • 0032561726 scopus 로고    scopus 로고
    • Leptin in estrogen receptor-containing neurons of the female rat hypothalamus
    • Diano S., Kalra S.P., Sakamoto H., and Horvath T.L. Leptin in estrogen receptor-containing neurons of the female rat hypothalamus. Brain Res. 812 (1998) 256-259
    • (1998) Brain Res. , vol.812 , pp. 256-259
    • Diano, S.1    Kalra, S.P.2    Sakamoto, H.3    Horvath, T.L.4
  • 10
    • 0030705157 scopus 로고    scopus 로고
    • Obesity and heart disease: a statement for healthcare professionals from the Nutrition Committee, American Heart Association
    • Eckel R.H. Obesity and heart disease: a statement for healthcare professionals from the Nutrition Committee, American Heart Association. Circulation 96 (1997) 3248-3250
    • (1997) Circulation , vol.96 , pp. 3248-3250
    • Eckel, R.H.1
  • 11
    • 0032177037 scopus 로고    scopus 로고
    • Unraveling the central nervous system pathways underlying responses to leptin
    • Elmquist J.K., Maratos-Flier E., Saper C.B., and Flier J.S. Unraveling the central nervous system pathways underlying responses to leptin. Nat. Neurosci. 1 (1998) 445-450
    • (1998) Nat. Neurosci. , vol.1 , pp. 445-450
    • Elmquist, J.K.1    Maratos-Flier, E.2    Saper, C.B.3    Flier, J.S.4
  • 12
    • 0030614331 scopus 로고    scopus 로고
    • Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
    • Fan W., Boston B.A., Kesterson R.A., Hruby V.J., and Cone R.D. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature 385 (1997) 165-168
    • (1997) Nature , vol.385 , pp. 165-168
    • Fan, W.1    Boston, B.A.2    Kesterson, R.A.3    Hruby, V.J.4    Cone, R.D.5
  • 13
    • 0037048669 scopus 로고    scopus 로고
    • Prevalence and trends in obesity among US adults, 1999-2000
    • Flegal K.M., Carroll M.D., Ogden C.L., and Johnson C.L. Prevalence and trends in obesity among US adults, 1999-2000. JAMA 288 (2002) 1723-1727
    • (2002) JAMA , vol.288 , pp. 1723-1727
    • Flegal, K.M.1    Carroll, M.D.2    Ogden, C.L.3    Johnson, C.L.4
  • 14
    • 0028793697 scopus 로고
    • Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action
    • Frederich R.C., Hamann A., Anderson S., Lollmann B., Lowell B.B., and Flier J.S. Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nat. Med. 1 (1995) 1311-1314
    • (1995) Nat. Med. , vol.1 , pp. 1311-1314
    • Frederich, R.C.1    Hamann, A.2    Anderson, S.3    Lollmann, B.4    Lowell, B.B.5    Flier, J.S.6
  • 15
    • 1842584949 scopus 로고    scopus 로고
    • Disruption of neural STAT3 causes obesity, diabetes, infertility and thermal dysregulation
    • Gao Q., Wolfgang M.J., Neschen S., Morino K., Horvath T.L., Shulman G.I., and Fu X.-Y. Disruption of neural STAT3 causes obesity, diabetes, infertility and thermal dysregulation. PNAS 101 (2004) 4661-4666
    • (2004) PNAS , vol.101 , pp. 4661-4666
    • Gao, Q.1    Wolfgang, M.J.2    Neschen, S.3    Morino, K.4    Horvath, T.L.5    Shulman, G.I.6    Fu, X.-Y.7
  • 16
    • 0022653095 scopus 로고
    • Synaptic remodelling in arcuate nucleus after injection of estradiol valerate in adult female rats
    • Garcia-Segura L., Baetens D., and Naftolin F. Synaptic remodelling in arcuate nucleus after injection of estradiol valerate in adult female rats. Brain Res. 366 (1986) 131-136
    • (1986) Brain Res. , vol.366 , pp. 131-136
    • Garcia-Segura, L.1    Baetens, D.2    Naftolin, F.3
  • 17
    • 0036162117 scopus 로고    scopus 로고
    • The neuroanatomical axis for control of energy balance
    • Grill H.J., and Kaplan J.M. The neuroanatomical axis for control of energy balance. Front. Neuroendocrinol. 23 (2002) 2-40
    • (2002) Front. Neuroendocrinol. , vol.23 , pp. 2-40
    • Grill, H.J.1    Kaplan, J.M.2
  • 18
    • 0032130554 scopus 로고    scopus 로고
    • Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons
    • Hahn T.M., Breininger J.F., Baskin D.G., and Schwartz M.W. Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons. Nat. Neurosci. 1 (1998) 271-272
    • (1998) Nat. Neurosci. , vol.1 , pp. 271-272
    • Hahn, T.M.1    Breininger, J.F.2    Baskin, D.G.3    Schwartz, M.W.4
  • 21
    • 0031026864 scopus 로고    scopus 로고
    • Lack of gonadotrophin positive feedback in the male rat predicts lack of estrogen-induced synaptic plasticity in the arcuate nucleus
    • Horvath T.L., Garcia-Segura L.M., and Naftolin F. Lack of gonadotrophin positive feedback in the male rat predicts lack of estrogen-induced synaptic plasticity in the arcuate nucleus. Neuroendocrinology 65 (1997) 136-141
    • (1997) Neuroendocrinology , vol.65 , pp. 136-141
    • Horvath, T.L.1    Garcia-Segura, L.M.2    Naftolin, F.3
  • 22
    • 0030962452 scopus 로고    scopus 로고
    • Control of gonadotrophin feedback: the role of estrogen-induced hypothalamic synaptic plasticity
    • Horvath T.L., Garcia-Segura L.M., and Naftolin F. Control of gonadotrophin feedback: the role of estrogen-induced hypothalamic synaptic plasticity. Gynec. Endocrin. 11 (1997) 139-143
    • (1997) Gynec. Endocrin. , vol.11 , pp. 139-143
    • Horvath, T.L.1    Garcia-Segura, L.M.2    Naftolin, F.3
  • 23
    • 33746300042 scopus 로고    scopus 로고
    • Horvath, T.L., Leedom, L., Garcia-Segura, L.M., Naftolin, F. (1995) Estrogen-induced hypothalamic synaptic plasticity; implications for the regulation of gonadotrophins. In: Smith, M.S. (Ed.) Current Opinion in Endocrinology and Diabetes, Lippincott Williams & Wilkins (LWW), Vol. 2. pp. 186-190.
  • 24
    • 0033081871 scopus 로고    scopus 로고
    • Synaptic interaction between hypocretin (orexin) and NPY cells in the rodent and primate hypothalamus - a novel hypothalamic circuit implicated in metabolic and endocrine regulations
    • Horvath T.L., Diano S., and Van den Pol A.N. Synaptic interaction between hypocretin (orexin) and NPY cells in the rodent and primate hypothalamus - a novel hypothalamic circuit implicated in metabolic and endocrine regulations. J Neurosci. 19 (1999) 1072-1087
    • (1999) J Neurosci. , vol.19 , pp. 1072-1087
    • Horvath, T.L.1    Diano, S.2    Van den Pol, A.N.3
  • 26
    • 0033038418 scopus 로고    scopus 로고
    • Interacting appetite regulating pathways in the hypothalamic regulation of body weight
    • Kalra S.P., Xu B., Dube M.G., Pu S., Horvath T.L., and Kalra P.S. Interacting appetite regulating pathways in the hypothalamic regulation of body weight. Endocrinol. Rev. 20 (1999) 67-100
    • (1999) Endocrinol. Rev. , vol.20 , pp. 67-100
    • Kalra, S.P.1    Xu, B.2    Dube, M.G.3    Pu, S.4    Horvath, T.L.5    Kalra, P.S.6
  • 27
    • 0034619522 scopus 로고    scopus 로고
    • Hormonal regulation of hippocampal morphology involves subcortical mediation
    • Leranth C., Sahanbrough M., and Horvath T.L. Hormonal regulation of hippocampal morphology involves subcortical mediation. Neuroscience 101 (2000) 349-356
    • (2000) Neuroscience , vol.101 , pp. 349-356
    • Leranth, C.1    Sahanbrough, M.2    Horvath, T.L.3
  • 28
    • 0034284520 scopus 로고    scopus 로고
    • Leptin receptor, NPY, POMC mRNA expression in the diet-induced obese mouse brain
    • Lin S., Storlien L.H., and Huang X. Leptin receptor, NPY, POMC mRNA expression in the diet-induced obese mouse brain. Brain Res. 875 (2000) 89-95
    • (2000) Brain Res. , vol.875 , pp. 89-95
    • Lin, S.1    Storlien, L.H.2    Huang, X.3
  • 30
    • 0028237111 scopus 로고
    • Structural dynamics of neural plasticity in the supraoptic nucleus of the rat hypothalamus during dehydration and rehydration
    • Miyata S., Nakashima T., and Kiyohara T. Structural dynamics of neural plasticity in the supraoptic nucleus of the rat hypothalamus during dehydration and rehydration. Brain Res. Bull. 34 (1994) 169-175
    • (1994) Brain Res. Bull. , vol.34 , pp. 169-175
    • Miyata, S.1    Nakashima, T.2    Kiyohara, T.3
  • 31
    • 0031888157 scopus 로고    scopus 로고
    • Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting in ob/ob and db/db mice, but is stimulated by leptin
    • Mizuno T.M., Kleopoulos S.P., Bergen H.T., Roberts J.L., Priest C.A., and Mobbs C.V. Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting in ob/ob and db/db mice, but is stimulated by leptin. Diabetes 47 (1998) 294-297
    • (1998) Diabetes , vol.47 , pp. 294-297
    • Mizuno, T.M.1    Kleopoulos, S.P.2    Bergen, H.T.3    Roberts, J.L.4    Priest, C.A.5    Mobbs, C.V.6
  • 32
    • 0030459719 scopus 로고    scopus 로고
    • Synaptic remodeling in the arcuate nucleus during the estrus cycle is induced by estrogen and precedes the midcycle gonadotrophin surge
    • Naftolin F., Mor G., Horvath T.L., Luquin S., Fajer A.B., Kohen F., and Garcia-Segura L.M. Synaptic remodeling in the arcuate nucleus during the estrus cycle is induced by estrogen and precedes the midcycle gonadotrophin surge. Endocrinology 137 (1996) 5576-5580
    • (1996) Endocrinology , vol.137 , pp. 5576-5580
    • Naftolin, F.1    Mor, G.2    Horvath, T.L.3    Luquin, S.4    Fajer, A.B.5    Kohen, F.6    Garcia-Segura, L.M.7
  • 33
    • 0029934266 scopus 로고
    • Potential neuronal mechanisms of estrogen actions in synaptogenesis and synaptic plasticity
    • Naftolin F., Leranth C., Horvath T.L., and Garcia-Segura L.M. Potential neuronal mechanisms of estrogen actions in synaptogenesis and synaptic plasticity. Cell. Mol. Neurobiol. 16 (1995) 213-223
    • (1995) Cell. Mol. Neurobiol. , vol.16 , pp. 213-223
    • Naftolin, F.1    Leranth, C.2    Horvath, T.L.3    Garcia-Segura, L.M.4
  • 34
    • 0037315042 scopus 로고    scopus 로고
    • Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia
    • Niswender K.D., Morrison C.D., Clegg D.J., Olson R., Baskin D.G., Myers Jr. M.G., Seeley R.J., and Schwartz M.W. Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia. Diabetes 52 (2003) 227-231
    • (2003) Diabetes , vol.52 , pp. 227-231
    • Niswender, K.D.1    Morrison, C.D.2    Clegg, D.J.3    Olson, R.4    Baskin, D.G.5    Myers Jr., M.G.6    Seeley, R.J.7    Schwartz, M.W.8
  • 36
    • 0037430755 scopus 로고    scopus 로고
    • Estradiol affects axo-somatic contacts of neuroendocrine cells in the arcuate nucleus of adult rats
    • Parducz A., Zsarnovszky A., Naftolin F., and Horvath T.L. Estradiol affects axo-somatic contacts of neuroendocrine cells in the arcuate nucleus of adult rats. Neuroscience 117 (2003) 791-794
    • (2003) Neuroscience , vol.117 , pp. 791-794
    • Parducz, A.1    Zsarnovszky, A.2    Naftolin, F.3    Horvath, T.L.4
  • 38
    • 0033780625 scopus 로고    scopus 로고
    • The role of gastrointestinal vagal afferents in the control of food intake: current prospects
    • Schwartz G.J. The role of gastrointestinal vagal afferents in the control of food intake: current prospects. Nutrition 16 (2000) 866-873
    • (2000) Nutrition , vol.16 , pp. 866-873
    • Schwartz, G.J.1
  • 39
    • 0030775971 scopus 로고    scopus 로고
    • Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus
    • Schwartz M.W., Seeley R.J., Woods S.C., Weigle D.S., Campfield L.A., Burn P., and Baskin D.G. Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus. Diabetes 46 (1997) 2119-2123
    • (1997) Diabetes , vol.46 , pp. 2119-2123
    • Schwartz, M.W.1    Seeley, R.J.2    Woods, S.C.3    Weigle, D.S.4    Campfield, L.A.5    Burn, P.6    Baskin, D.G.7
  • 40
    • 0035936764 scopus 로고    scopus 로고
    • Obesity and the regulation of energy balance
    • Spiegelman B.M., and Flier J.S. Obesity and the regulation of energy balance. Cell 104 (2001) 531-543
    • (2001) Cell , vol.104 , pp. 531-543
    • Spiegelman, B.M.1    Flier, J.S.2
  • 41
    • 15244351734 scopus 로고    scopus 로고
    • Activity-dependent regulation of synapse and dendritic spine morphology in developing barrel cortex requires phospholipase C-β1 signalling
    • Spires T.L., Molnar Z., Kind P.C., Cordery P.M., Upton A.L., Blakemore C., and Hannan A.J. Activity-dependent regulation of synapse and dendritic spine morphology in developing barrel cortex requires phospholipase C-β1 signalling. Cereb. Cortex 15 (2005) 385-393
    • (2005) Cereb. Cortex , vol.15 , pp. 385-393
    • Spires, T.L.1    Molnar, Z.2    Kind, P.C.3    Cordery, P.M.4    Upton, A.L.5    Blakemore, C.6    Hannan, A.J.7
  • 43
    • 0031915248 scopus 로고    scopus 로고
    • Reorganization of the dendritic trees of oxytocin and vasopressin neurons of the rat supraoptic nucleus during lactation
    • Stern J., and Armstrong W. Reorganization of the dendritic trees of oxytocin and vasopressin neurons of the rat supraoptic nucleus during lactation. J. Neurosci. 18 (1998) 841-853
    • (1998) J. Neurosci. , vol.18 , pp. 841-853
    • Stern, J.1    Armstrong, W.2
  • 44
    • 0031886937 scopus 로고    scopus 로고
    • Factors governing activity-dependent structural plasticity of the hypothalamoneurohypophysial system
    • Theodosis D., El Majdoubi M., Pierre K., and Poulain D. Factors governing activity-dependent structural plasticity of the hypothalamoneurohypophysial system. Cell. Mol. Neurobiol. 18 (1998) 285-298
    • (1998) Cell. Mol. Neurobiol. , vol.18 , pp. 285-298
    • Theodosis, D.1    El Majdoubi, M.2    Pierre, K.3    Poulain, D.4
  • 45
    • 0025954614 scopus 로고
    • Retention of embryonic features by an adult neuronal system capable of plasticity: polysialylated neural cell adhesion molecule in the hypothalamo-neurohypophysial system
    • Theodosis D., Rougon G., and Poulain D. Retention of embryonic features by an adult neuronal system capable of plasticity: polysialylated neural cell adhesion molecule in the hypothalamo-neurohypophysial system. Proc. Natl. Acad. Sci. USA 88 (1991) 5494-5498
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5494-5498
    • Theodosis, D.1    Rougon, G.2    Poulain, D.3
  • 47
    • 0031046169 scopus 로고    scopus 로고
    • Evidence for seasonal plasticity in the gonadotropin-releasing hormone (GnRH) system of the ewe: changes in synaptic inputs onto GnRH neurons
    • Xiong J., Karsch F., and Lehman M. Evidence for seasonal plasticity in the gonadotropin-releasing hormone (GnRH) system of the ewe: changes in synaptic inputs onto GnRH neurons. Endocrinology 138 (1997) 1240-1250
    • (1997) Endocrinology , vol.138 , pp. 1240-1250
    • Xiong, J.1    Karsch, F.2    Lehman, M.3
  • 48
    • 0027362079 scopus 로고
    • Chronic intracerebroventricular neuropeptide-Y administration to normal rats mimics hormonal and metabolic changes of obesity
    • Zarjevski N., Cusin I., Vettor R., Rohner-Jeanrenaud F., and Jeanrenaud B. Chronic intracerebroventricular neuropeptide-Y administration to normal rats mimics hormonal and metabolic changes of obesity. Endocrinology 133 (1993) 1753-1758
    • (1993) Endocrinology , vol.133 , pp. 1753-1758
    • Zarjevski, N.1    Cusin, I.2    Vettor, R.3    Rohner-Jeanrenaud, F.4    Jeanrenaud, B.5
  • 49
  • 50
    • 0035172417 scopus 로고    scopus 로고
    • Oestrogen-induced changes in the synaptology of the monkey (Cercopithecus aethiops) arcuate nucleus during gonadotropin feedback
    • Zsarnovszky A., Horvath T., Garcia-Segura L., Horvath B., and Naftolin F. Oestrogen-induced changes in the synaptology of the monkey (Cercopithecus aethiops) arcuate nucleus during gonadotropin feedback. J. Neuroendocrinol. 13 (2001) 22-28
    • (2001) J. Neuroendocrinol. , vol.13 , pp. 22-28
    • Zsarnovszky, A.1    Horvath, T.2    Garcia-Segura, L.3    Horvath, B.4    Naftolin, F.5


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