Simultaneous determination of gemcitabine di- and triphosphate in human blood mononuclear and cancer cells by RP-HPLC and UV detection

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 840, Issue 1, 2006, Pages 44-49

  Losa, R ^a   Sierra, M I ^a   Gion M O ^a   Esteban, E ^a   Buesa, J M ^a  

^a DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

Author keywords

dFdCDP; dFdCTP; Gemcitabine; Peripheral blood mononuclear cells; Reverse phase HPLC

Indexed keywords

ADENOSINETRIPHOSPHATE; ASSAYS; BIOMEDICAL ENGINEERING; CELLS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PATIENT TREATMENT; SENSITIVITY ANALYSIS; TUMORS; ULTRAVIOLET DETECTORS;

GEMCITABINE; GEMCITABINE DIPHOSPHATE (DFDCTP); GEMCITABINE TRIPHOSPHATE (DFDCDP); PERIPHERAL BLOOD MONONUCLEAR CELLS; REVERSE-PHASE HPLC;

BLOOD;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; GEMCITABINE; GEMCITABINE DIPHOSPHATE; GEMCITABINE TRIPHOSPHATE; NUCLEOTIDE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; BLOOD CELL; CANCER CELL; CELL GROWTH; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG DETERMINATION; ELUTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MONONUCLEAR CELL; PARTICLE SIZE; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ROOM TEMPERATURE; SENSITIVITY ANALYSIS; SEPARATION TECHNIQUE; ULTRAVIOLET RADIATION; VALIDATION STUDY;

ANTIMETABOLITES, ANTINEOPLASTIC; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYCYTIDINE; FEMALE; HUMANS; MONOCYTES; OVARIAN NEOPLASMS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 33746292446     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.04.036     Document Type: Article

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