Focal cortical dysplasia: Pathophysiological approach

Child's Nervous System

Volumn 22, Issue 8, 2006, Pages 827-833

  Hodozuka, Akira ^a   Tsuda, Hiroshige ^a   Hashizume, Kiyotaka ^a   Tanaka, Tatsuya ^a  

^a ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

Focal cortical; GABA receptors; Pathophysiological approach

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; ANTICONVULSIVE AGENT; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; KAINIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ADOLESCENT; ADULT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BENIGN CHILDHOOD EPILEPSY; BRAIN SURGERY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CORTICAL DYSPLASIA; ELECTROCORTICOGRAPHY; ELECTROENCEPHALOGRAM; EPILEPTIC DISCHARGE; EPILEPTIC FOCUS; EPILEPTOGENESIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFANT; INTRACTABLE EPILEPSY; INTRAOPERATIVE PERIOD; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RAT; RAT STRAIN; REVIEW; SENSORIMOTOR CORTEX; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SPIKE WAVE;

ADOLESCENT; ANIMALS; ANIMALS, NEWBORN; AUTORADIOGRAPHY; BEHAVIOR, ANIMAL; BRAIN DISEASES; BRAIN MAPPING; CEREBRAL CORTEX; CHILD; ELECTROENCEPHALOGRAPHY; EPILEPSY; FEMALE; FLUMAZENIL; GAMMA-AMINOBUTYRIC ACID; HUMANS; IMMUNOHISTOCHEMISTRY; IODINE RADIOISOTOPES; KAINIC ACID; MALE; NERVOUS SYSTEM MALFORMATIONS; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 33746286057     PISSN: 02567040     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00381-006-0136-1     Document Type: Review

References (16)

1. Aronica E, Gorter JA, Jansen GH et al (2003) Expression and cell distribution of group I and group II metabotropic glutamate receptor subtypes in Taylor-type focal cortical dysplasia. Epilepsia 44:785-795
2. Benardete EA, Kriegstein AR (2002) Increased excitability and decreased sensitivity to GABA in an animal model of dysplastic cortex. Epilepsia 43:970-982
3. Hagemann G, Kluska MM, Redecker C et al (2003) Distribution of glutamate receptor subunits in experimentally induced cortical malformations. Neuroscience 117:991-1002
4. Humphreys P, Rosen GD, Press DM et al (1991) Freezing lesions of the developing brain: A model for cerebrocortical microgyria. J Neuropathol Exp Neurol 50:145-160
5. Lee KS, Chen ZF, Schottler F, Bertram E (1996) Spontaneous seizure activity in a rat with a genetic cortical heterotopia resembling the human syndrome of double cortex (abstract). Epilepsia 37:S70
6. Marret S, Mukendi R, Gadisseux JF et al (1995) Effect of ibonate on brain development: An excitotoxic mouse model of microgyria and posthypoxic-like lesions. J Neuropathol Exp Neurol 54:358-370
7. Mikuni N, Babb TL, Ying Z et al (1999) NMDA-receptors 1 and 2A/B coassembly increased in human epileptic focal cortical dysplasia. Epilepsia 40:1683-1687
8. Najm IM, Ying Z, Babb T et al (2000) Epileptogenicity correlated with increased N-methyl-D-aspartate receptor subunit NR2A/B in human focal cortical dysplasia. Epilepsia 41:971-976
9. Palmini A, Luders HO (2002) Classification issues in malformations caused by abnormalities of cortical development. Neurosurg Clin N Am 37:1-16
10. Roper SN, King MA, Abraham LA, Blillot MA (1997) Disinhibited in vitro neocortical slices containing experimentally induced cortical dysplasia demonstrate hyperexcitability. Epilepsy Res 26:443-449
11. Spreafico R, Battaglia G, Arcelli P et al (1998) Cortical dysplasia: An immunocytochemical study of three patients. Neurology 50:8-10
12. Tanaka T, Fujita T, Tanaka S et al (1991) Secondary generalization in kainic acid-induced focal seizures in unanesthetized cats. Jpn J Psychiatry Neurol 45:243-248
13. Tanaka T, Kaijima M, Yonemasu Y, Cepeda C (1985) Spontaneous secondarily generalized seizures induced by a single microinjection of kainic acid into unilateral amygdala in cats. Electroencephalogr Clin Neurophysiol 61:422-429
14. Tanaka T, Tanaka S, Fujita T et al (1992) Experimental complex partial seizures induced by a microinjection of kainic acid into limbic structures. Prog Neurobiol 38:317-334
15. Tanaka T, Tsuda H, Hashizume K et al (2005) Clinical application of experimental cortical dysplasia in rats. J Child Neurol 20:351-356
16. Yamamoto K, Tanaka T, Yonemasu Y (1995) Jacksonian seizure model induced by a kainic acid microinjection into unilateral sensorimotor cortex (in Japanese). No To Shinkei (Tokyo) 47:477-483