Use of mass spectrometry methods as a strategy for detection and determination of residual solvents in pharmaceutical products

Analytical Chemistry

Volumn 78, Issue 14, 2006, Pages 4901-4908

  Pavón, José Luis Pérez ^a   Del Nogal Sánchez, Miguel ^a   Pinto, Carmelo García ^a   Laespada, M Esther Fernández ^a   Cordero, Bernardo Moreno ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DIRECT COUPLING; FAST GAS CHROMATOGRAPHY; HEADSPACE SAMPLER; SIGNAL RECORDING TIME;

CHEMICAL ANALYSIS; CHROMATOGRAPHIC ANALYSIS; IMPURITIES; MASS SPECTROMETERS; MASS SPECTROMETRY; SOLVENTS;

DRUG PRODUCTS;

2 PROPANOL; 4 METHYL 2 PENTANONE; ACETIC ACID ETHYL ESTER; ACETONE; ALCOHOL; BENZENE; BUTANOL; CARBON TETRACHLORIDE; CHLOROBENZENE; CHLOROFORM; CUMENE; CYCLOHEXANE; DICHLOROMETHANE; HEXANE; METHANOL; ORGANIC COMPOUND; PARA XYLENE; PENTANOL; PYRIDINE; SOLVENT; TERT BUTYL METHYL ETHER; TOLUENE; VOLATILE AGENT;

ANALYTIC METHOD; ANALYTICAL PARAMETERS; ARTICLE; ASSAY; CHEMICAL ANALYSIS; DRUG MANUFACTURE; GAS CHROMATOGRAPHY; HEADSPACE GENERATION FAST GAS CHROMATOGRAPHY MASS SPECTROMETRY; INFORMATION PROCESSING; MASS SPECTROMETRY; METHODOLOGY; PROCESS DEVELOPMENT; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; QUANTITATIVE STUDY; SAMPLE; STANDARD;

GAS CHROMATOGRAPHY-MASS SPECTROMETRY; SENSITIVITY AND SPECIFICITY; SOLVENTS;

EID: 33746260375     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac060426h     Document Type: Article

References (24)

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