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Volumn 9, Issue 4, 2006, Pages 449-454

Pharmacological approaches to ameliorating catabolic conditions

Author keywords

Anorexia; Cachexia; Debilitating illnesses; Malnutrition; Pharmacological therapy

Indexed keywords

ANABOLIC AGENT; ANTINEOPLASTIC AGENT; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRANCHED CHAIN AMINO ACID; CANNABINOID; CISAPRIDE; DEXAMETHASONE; DOXIFLURIDINE; DRONABINOL; FISH OIL; GESTAGEN; GLUCOCORTICOID; HYDRAZINE SULFATE; MACROLIDE; MEDROXYPROGESTERONE ACETATE; MEGESTROL ACETATE; MELATONIN; METHYLPREDNISOLONE; METOCLOPRAMIDE; NABILONE; NANDROLONE DECANOATE; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PENTOXIFYLLINE; PREDNISOLONE; PROKINETIC AGENT; RECOMBINANT GROWTH HORMONE; SEROTONIN ANTAGONIST; THALIDOMIDE; UNINDEXED DRUG;

EID: 33746253865     PISSN: 13631950     EISSN: 15353885     Source Type: Journal    
DOI: 10.1097/01.mco.0000232906.89662.bb     Document Type: Review
Times cited : (6)

References (34)
  • 2
    • 1942530864 scopus 로고    scopus 로고
    • Palliative nutritional intervention in addition to cyclooxygenase and erythropoietin treatment for patients with malignant disease: Effects on survival, metabolism, and function
    • Lundholm K, Daneryd P, Bosaeus I, et al. Palliative nutritional intervention in addition to cyclooxygenase and erythropoietin treatment for patients with malignant disease: effects on survival, metabolism, and function. Cancer 2004; 100:1967-1977.
    • (2004) Cancer , vol.100 , pp. 1967-1977
    • Lundholm, K.1    Daneryd, P.2    Bosaeus, I.3
  • 3
    • 0036460451 scopus 로고    scopus 로고
    • Protein-energy undernutrition and life-threatening complications among the hospitalized elderly
    • Sullivan DH, Bopp MM, Roberson PK. Protein-energy undernutrition and life-threatening complications among the hospitalized elderly. J Gen Intern Med 2002; 17:923-932.
    • (2002) J Gen Intern Med , vol.17 , pp. 923-932
    • Sullivan, D.H.1    Bopp, M.M.2    Roberson, P.K.3
  • 4
    • 5144234906 scopus 로고    scopus 로고
    • Prediction of daily energy expenditure during a feeding trial using measurements of resting energy expenditure, fat-free mass, or Harris-Benedict equations
    • Kien CL, Ugrasbul F. Prediction of daily energy expenditure during a feeding trial using measurements of resting energy expenditure, fat-free mass, or Harris-Benedict equations. Am J Clin Nutr 2004; 80:876-880.
    • (2004) Am J Clin Nutr , vol.80 , pp. 876-880
    • Kien, C.L.1    Ugrasbul, F.2
  • 5
    • 85026136040 scopus 로고    scopus 로고
    • The biochemical basis of metabolism in cancer cachexia
    • Tijerina AJ. The biochemical basis of metabolism in cancer cachexia. Dimens Crit Care Nurs 2004; 23:237-243.
    • (2004) Dimens Crit Care Nurs , vol.23 , pp. 237-243
    • Tijerina, A.J.1
  • 6
    • 0033567912 scopus 로고    scopus 로고
    • Cancer anorexia-cachexia syndrome: Are neuropeptides the key?
    • Inui A. Cancer anorexia-cachexia syndrome: are neuropeptides the key? Cancer Res 1999; 59:4493-4501.
    • (1999) Cancer Res , vol.59 , pp. 4493-4501
    • Inui, A.1
  • 7
    • 33746246601 scopus 로고    scopus 로고
    • Cancer anorexia: A neglected issue in the optimal management of cancer patients
    • Laviano A, De Luca S, Meguid MM, Fanelli FR. Cancer anorexia: a neglected issue in the optimal management of cancer patients. J Cancer Pain Sympt Pall 2005; 1:15-24. An excellent review of cancer anorexia-related pathophysiology and available treatment options. The authors urge providers to place importance on the positive impact that improving appetite and energy intake can have on a patient's psychological balance.
    • (2005) J Cancer Pain Sympt Pall , vol.1 , pp. 15-24
    • Laviano, A.1    De Luca, S.2    Meguid, M.M.3    Fanelli, F.R.4
  • 8
    • 0034611732 scopus 로고    scopus 로고
    • Central nervous system control of food intake
    • Schwartz MW, Woods SC, Porte D Jr, et al. Central nervous system control of food intake. Nature 2000; 404:661-671.
    • (2000) Nature , vol.404 , pp. 661-671
    • Schwartz, M.W.1    Woods, S.C.2    Porte Jr., D.3
  • 9
    • 19144368227 scopus 로고    scopus 로고
    • Prediction of DXA-determined whole body fat from skinfolds: Importance of including skinfolds from the thigh and calf in young, healthy men and women
    • Eston RG, Rowlands AV, Charlesworth S, et al. Prediction of DXA-determined whole body fat from skinfolds: importance of including skinfolds from the thigh and calf in young, healthy men and women. Eur J Clin Nutr 2005; 59:695-702. A small but well structured study on the utility of anthropometric tests such as dual X-ray absorptiometry on investigating the relationship of percentage body fat.
    • (2005) Eur J Clin Nutr , vol.59 , pp. 695-702
    • Eston, R.G.1    Rowlands, A.V.2    Charlesworth, S.3
  • 10
    • 24344455622 scopus 로고    scopus 로고
    • Nutritional care of the obese intensive care unit patient
    • Elamin EM. Nutritional care of the obese intensive care unit patient. Curr Opin Crit Care 2005; 11:300-303. A through review of metabolic changes in critically ill obese patients that includes recommendations for optimizing nutritional support in this patient population. The authors stress the importance of early nutritional support and the optimization of protein administration using a hypocaloric, high-protein regimen. The authors also recommend the use of adjusted body weight for calculating energy expenditure.
    • (2005) Curr Opin Crit Care , vol.11 , pp. 300-303
    • Elamin, E.M.1
  • 12
    • 0035064287 scopus 로고    scopus 로고
    • Managing cancer-related anorexia/cachexia
    • Mantovani G, Maccio A, Massa E, et al. Managing cancer-related anorexia/cachexia. Drugs 2001; 61:499-514.
    • (2001) Drugs , vol.61 , pp. 499-514
    • Mantovani, G.1    Maccio, A.2    Massa, E.3
  • 13
    • 0142156632 scopus 로고    scopus 로고
    • What we have learned about cachexia in gastrointestinal cancer
    • Palesty JA, Dudrick SJ. What we have learned about cachexia in gastrointestinal cancer. Dig Dis 2003; 21:198-213.
    • (2003) Dig Dis , vol.21 , pp. 198-213
    • Palesty, J.A.1    Dudrick, S.J.2
  • 14
    • 0033975322 scopus 로고    scopus 로고
    • The cancer anorexia-cachexia syndrome
    • Nelson KA. The cancer anorexia-cachexia syndrome. Semin Oncol 2000; 27:64-68.
    • (2000) Semin Oncol , vol.27 , pp. 64-68
    • Nelson, K.A.1
  • 15
    • 1642634608 scopus 로고    scopus 로고
    • Systematic review of megestrol acetate in the treatment of anorexia-cachexia syndrome
    • Pascual LA, Roque IM, Urrutia CG, et al. Systematic review of megestrol acetate in the treatment of anorexia-cachexia syndrome. J Pain Symptom Manage 2004; 27:360-369.
    • (2004) J Pain Symptom Manage , vol.27 , pp. 360-369
    • Pascual, L.A.1    Roque, I.M.2    Urrutia, C.G.3
  • 16
    • 0034526975 scopus 로고    scopus 로고
    • Quality of life and stimulation of weight gain after treatment with megestrol acetate: Correlation between cytokine levels and nutritional status, appetite in geriatric patients with wasting syndrome
    • Yeh S, Wu SY, Levine DM, et al. Quality of life and stimulation of weight gain after treatment with megestrol acetate: correlation between cytokine levels and nutritional status, appetite in geriatric patients with wasting syndrome. J Nutr Health Aging 2000; 4:246-251.
    • (2000) J Nutr Health Aging , vol.4 , pp. 246-251
    • Yeh, S.1    Wu, S.Y.2    Levine, D.M.3
  • 17
    • 21844436308 scopus 로고    scopus 로고
    • Megestrol acetate for the treatment of anorexia-cachexia syndrome
    • Berenstein E.G., Ortiz Z. Megestrol acetate for the treatment of anorexia-cachexia syndrome. Cochrane Database Syst Rev 2005; (2):CD004310. A metaanalysis of 30 trials evaluating therapy with megestrol acetate in patients with cancer, AIDS and other underlying pathologies. The review found an improvement in appetite and weight gain in cancer patients on megestrol acetate compared with those on placebo. No conclusion could be made regarding quality of life.
    • (2005) Cochrane Database Syst Rev , Issue.2
    • Berenstein, E.G.1    Ortiz, Z.2
  • 18
    • 0033771667 scopus 로고    scopus 로고
    • Central nervous system mechanisms contributing to the cachexia-anorexia syndrome
    • Plata-Salaman CR. Central nervous system mechanisms contributing to the cachexia-anorexia syndrome. Nutrition 2000; 16:1009-1012.
    • (2000) Nutrition , vol.16 , pp. 1009-1012
    • Plata-Salaman, C.R.1
  • 19
    • 0035067434 scopus 로고    scopus 로고
    • High-dose progestins for the treatment of cancer anorexia-cachexia syndrome: A systemic review of randomized clinical trials
    • Maltoni M, Nanni O, Scarpi E, et al. High-dose progestins for the treatment of cancer anorexia-cachexia syndrome: a systemic review of randomized clinical trials. Ann Oncol 2001; 12:289-300.
    • (2001) Ann Oncol , vol.12 , pp. 289-300
    • Maltoni, M.1    Nanni, O.2    Scarpi, E.3
  • 20
    • 9044244145 scopus 로고    scopus 로고
    • Randomized double-blind placebo-controlled trial of cisplatin and etoposide plus megestrol acetate/placebo in extensive-stage small-cell lung cancer: A North Central Cancer Treatment Group study
    • Rowland KM Jr, Loprinzi CL, Shaw EG, et al. Randomized double-blind placebo-controlled trial of cisplatin and etoposide plus megestrol acetate/placebo in extensive-stage small-cell lung cancer: a North Central Cancer Treatment Group study. J Clin Oncol 1996; 14:135-141.
    • (1996) J Clin Oncol , vol.14 , pp. 135-141
    • Rowland Jr., K.M.1    Loprinzi, C.L.2    Shaw, E.G.3
  • 21
    • 0035848818 scopus 로고    scopus 로고
    • Leptin-regulated endocannabinoids are involved in maintaining food intake
    • Di Marzo V, Goparaju SK, Wang L, et al. Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature 2001; 410:822-825.
    • (2001) Nature , vol.410 , pp. 822-825
    • Di Marzo, V.1    Goparaju, S.K.2    Wang, L.3
  • 22
    • 13844319704 scopus 로고    scopus 로고
    • Treatment with nandrolone decanoate and megestrol acetate in HIV-infected men
    • Cuerda C, Zugasti A, Breton I, et al. Treatment with nandrolone decanoate and megestrol acetate in HIV-infected men. Nutr Clin Pract 2005; 20:93-97. A small study in HIV-infected men evaluating the effects of nandrolone and megestrol on various indicators including anthropometric measurements and quality of life. The positive findings included significant weight gain and improvement in muscle strength.
    • (2005) Nutr Clin Pract , vol.20 , pp. 93-97
    • Cuerda, C.1    Zugasti, A.2    Breton, I.3
  • 23
    • 0033781030 scopus 로고    scopus 로고
    • Hypothalamic dopamine and serotonin in the regulation of food intake
    • Meguid MM, Fetissov SO, Varma M, et al. Hypothalamic dopamine and serotonin in the regulation of food intake. Nutrition 2000; 16:843-857.
    • (2000) Nutrition , vol.16 , pp. 843-857
    • Meguid, M.M.1    Fetissov, S.O.2    Varma, M.3
  • 24
    • 0025977730 scopus 로고
    • A study of cyproheptadine in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome
    • Moertel CG, Kvols LK, Rubin J. A study of cyproheptadine in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome. Cancer 1991; 67:33-36.
    • (1991) Cancer , vol.67 , pp. 33-36
    • Moertel, C.G.1    Kvols, L.K.2    Rubin, J.3
  • 25
    • 0033566970 scopus 로고    scopus 로고
    • Serotonergic blockade in the treatment of the cancer anorexia-cachexia syndrome
    • Edelman MJ, Gandara DR, Meyers FJ, et al. Serotonergic blockade in the treatment of the cancer anorexia-cachexia syndrome. Cancer 1999; 86:684-688.
    • (1999) Cancer , vol.86 , pp. 684-688
    • Edelman, M.J.1    Gandara, D.R.2    Meyers, F.J.3
  • 26
    • 0035328839 scopus 로고    scopus 로고
    • Mechanism of attenuation of skeletal muscle protein catabolism in cancer cachexia by eicosapentaenoic acid
    • Whitehouse AS, Smith HJ, Drake JL. Mechanism of attenuation of skeletal muscle protein catabolism in cancer cachexia by eicosapentaenoic acid. Cancer Res 2001; 61:3604-3609.
    • (2001) Cancer Res , vol.61 , pp. 3604-3609
    • Whitehouse, A.S.1    Smith, H.J.2    Drake, J.L.3
  • 27
    • 0029936742 scopus 로고    scopus 로고
    • The effect of polyunsaturated fatty acids on the progress of cachexia in patients with pancreatic cancer
    • Wigmore SJ, Ross JA, Falconer JS, et al. The effect of polyunsaturated fatty acids on the progress of cachexia in patients with pancreatic cancer. Nutrition 1996; 12:27-30.
    • (1996) Nutrition , vol.12 , pp. 27-30
    • Wigmore, S.J.1    Ross, J.A.2    Falconer, J.S.3
  • 28
    • 33746246599 scopus 로고    scopus 로고
    • Effect of enteral nutrition with eicosapentaenoic acid (EPA), gamma-linolenic acid (GLA), and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome (ARDS)
    • Elamin EM, Hughes LF, Drew D. Effect of enteral nutrition with eicosapentaenoic acid (EPA), gamma-linolenic acid (GLA), and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome (ARDS). Chest 2005; 128:S225. This prospective study demonstrates the benefits of immune-enhancing enteral nutrition on patients with acute respiratory distress syndrome. Overall, there was a statistically significant reduction in length of intensive care unit stay and 28-day mortality.
    • (2005) Chest , vol.128
    • Elamin, E.M.1    Hughes, L.F.2    Drew, D.3
  • 29
    • 0037208642 scopus 로고    scopus 로고
    • Effect of fish oil on appetite and other symptoms in patients with advanced cancer and anorexia/cachexia: A doubleblind, placebo-controlled study
    • Bruera E, Strasser F, Palmer JL, et al. Effect of fish oil on appetite and other symptoms in patients with advanced cancer and anorexia/cachexia: a doubleblind, placebo-controlled study. J Clin Oncol 2003; 21:129-134.
    • (2003) J Clin Oncol , vol.21 , pp. 129-134
    • Bruera, E.1    Strasser, F.2    Palmer, J.L.3
  • 30
    • 0035744480 scopus 로고    scopus 로고
    • Management of catabolism in metabolically stressed patients: A literature survey about growth hormone application
    • Raguso CA, Genton L, Kyle U, et al. Management of catabolism in metabolically stressed patients: a literature survey about growth hormone application. Curr Opin Clin Nutr Metab Care 2001; 4:313-320.
    • (2001) Curr Opin Clin Nutr Metab Care , vol.4 , pp. 313-320
    • Raguso, C.A.1    Genton, L.2    Kyle, U.3
  • 31
    • 0038121116 scopus 로고    scopus 로고
    • Growth hormone therapy in adult
    • Cummings DE, Merriam GR. Growth hormone therapy in adult. Annu Rev Med 2003; 54:513-533.
    • (2003) Annu Rev Med , vol.54 , pp. 513-533
    • Cummings, D.E.1    Merriam, G.R.2
  • 32
    • 13844299005 scopus 로고    scopus 로고
    • Impact of fish oil and melatonin on cachexia in patients with advanced gastrointestinal cancer: A randomized pilot study
    • Persson C, Glimelius B, Ronnelid J, Nygren P. Impact of fish oil and melatonin on cachexia in patients with advanced gastrointestinal cancer: a randomized pilot study. Nutrition 2005; 21:170-178. Twenty-four patients not amenable to standard anticancer treatment secondary to cachexia were randomized to receive fish oil, melatonin or a combination of both. The study supported the added benefit of melatonin especially when combined with fish oil.
    • (2005) Nutrition , vol.21 , pp. 170-178
    • Persson, C.1    Glimelius, B.2    Ronnelid, J.3    Nygren, P.4
  • 33
    • 0034692466 scopus 로고    scopus 로고
    • Thalidomide for the treatment of AIDS-associated wasting
    • Kaplan G, Thomas S, Fierer DS, et al. Thalidomide for the treatment of AIDS-associated wasting. AIDS Res Hum Retroviruses 2000; 16:1345-1355.
    • (2000) AIDS Res Hum Retroviruses , vol.16 , pp. 1345-1355
    • Kaplan, G.1    Thomas, S.2    Fierer, D.S.3
  • 34
    • 15444379633 scopus 로고    scopus 로고
    • Thalidomide in the treatment of cancer cachexia: A randomized placebo controlled trial
    • Gordon JN, Trebble TM, Ellis RD, et al. Thalidomide in the treatment of cancer cachexia: a randomized placebo controlled trial. GUT 2005; 54:540-545. A randomized placebo-controlled trial of 33 patients with cachexia secondary to advanced pancreatic cancer. The authors concluded that thalidomide was associated with a reduction in weight loss and lean body mass in this patient population.
    • (2005) GUT , vol.54 , pp. 540-545
    • Gordon, J.N.1    Trebble, T.M.2    Ellis, R.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.