Autoantibody against cardiac β1-adrenoceptor induces apoptosis in cultured neonatal rat cardiomyocytes

Acta Biochimica et Biophysica Sinica

Volumn 38, Issue 7, 2006, Pages 443-449

  Gao, Yan ^a   Liu, Hui Rong ^a   Zhao, Rong Rui ^a   Zhi, Jian Ming ^b  

^a SHANXI MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

1 adrenoceptor; Apoptosis; Autoantibody; Rat cardiomyocyte

Indexed keywords

RATTUS NORVEGICUS;

AUTOANTIBODY; BETA 1 ADRENERGIC RECEPTOR; DNA FRAGMENT; IMMUNOGLOBULIN G; ISOPRENALINE; PEPTIDE;

ANIMAL; APOPTOSIS; ARTICLE; BIOLOGICAL MODEL; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; FLOW CYTOMETRY; HEART MUSCLE CELL; HEART RATE; HUMAN; IMMUNOLOGY; NEWBORN; PROTEIN TERTIARY STRUCTURE; RAT; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; AUTOANTIBODIES; CELLS, CULTURED; DNA FRAGMENTATION; FLOW CYTOMETRY; HEART RATE; HUMANS; IMMUNOGLOBULIN G; ISOPROTERENOL; MODELS, CARDIOVASCULAR; MYOCYTES, CARDIAC; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA-1;

EID: 33746237540     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1111/j.1745-7270.2006.00185.x     Document Type: Article

References (24)

1. 1- adrenergic receptor in patients with idiopathic dilated cardiomyopathy. J Clin Invest 1990, 86: 1658-1663
2. 1-adrenoceptor antibodies in heart failture. Am J Cardiol 1999, 83: 75H-79H
3. Fu ML, Hoebeke J, Matsui S, Matoba M, Magnusson Y, Hedner T, Herlitz H et al. Autoantibodies against cardiac G-protein-coupled receptors define different populations with cardiomyopathies but not with hypertension. Clin Immunopathol 1994, 72: 15-20
4. 1-adrenergic receptors are associated with reduced cardiac function in chronic heart failure. Circulation 1999, 99: 649-654
5. 1-adrenoceptor antibodies are not associated with cardiomyopathies secondary to valvular or hypertensive heart disease. Am J Coll Cardiol 1999, 34: 1545-1551
6. Christ T, Adolph E, Schindelhauer S, Wettwer E, Dobrev D, Wallukat G, Ravens U. Effects of immunoglobulin G from patients with dilated cardiomyopathy on rat cardiomyocytes. Basic Clin Pharmacol Toxicol 2005, 96: 445-452
7. Liu HR, Zhao RR, Jiao XY, Wang YY, Fu M. Relationship of myocardial remodeling to the genesis of serum autoantibodies to cardiac β-1 adrenoceptors and muscarinic type-2 acetylcholine receptors in rats. J Am Coll Cardiol 2002, 39: 1866-1873
8. Matsui S, Zong ZP, Han JF, Katsuda S, Yamaguchi N, Fu ML. Amiodarone minimizes experimental autoimmune myocarditis in rats. Eur J Pharmacol 2003, 469: 165-173
9. Iwai-Kanai E, Hasegawa K, Araki M, Kakita T, Morimoto T, Sasayama S. α- and β-adrenergic pathways differentially regulate cell type-specific apoptosis in rat cardiac myocytes. Circulation 1999, 100: 305-311
10. Andreka P, Nadhazi Z, Muzes G, Szantho G, Vandor L, Konya L, Turner MS et al. Possible therapeutic targets in cardiac myocyte apoptosis. Curr Pharm Des 2004, 10: 2445-2461
11. 2-adrenergic receptors on cardiac myocyte apoptosis: Role of a pertussis toxin-sensitive G protein. Circulation 1999, 100: 2210-2212
12. 1-adrenergic receptor recognized in idiopathic dilated cardiomyopathy. Hybridoma 2000, 19: 135-142
13. 1-adrenoceptor expression in neonatal rat cardiomyocytes. Circulation 1998, 98: 2470-2476
14. 1-adrenoceptor antibodies induce positive inotropic response in isolated cardiomyocytes. Eur J Pharmacol 2001, 423: 115-119
15. 2-muscarinic receptor during development of renovascular hypertension in rats. Acta Biochim Biophys Sin 2004, 36: 793-797
16. Simpon P, Savion S. Differentiation of rat myocytes in single cell cultures with and without proliferating nonmyocardial cells. Cross-striations, ultrastructure, and chronotropic response to isoprenaline. Circ Res 1982, 50: 101-116
17. Moore KJ, Matlashewski G. Intracellular infection by Leishmania donovani inhibits macrophage apoptosis. J Immunol 1994, 152: 2930-2935
18. Hu JH, Jiang J, Ma YH, Yang N, Zhang MH, Wu M, Fei J et al. Enhancement of germ cell apoptosis induced by ethanol in transgenic mice overexpressing Fas ligand. Cell Res 2003, 13: 361-367
19. Okazaki T, Honjo T. Pathogenic roles of cardiac autoantibodies in dilated cardiomyopathy. Trends Mol Med 2005, 11: 322-326
20. Buvall L, Bollano E, Chen J, Shultze W, Fu M. Phenotype of early cardiomyopathic changes induced by active immunization of rats with a synthetic peptide corresponding to the second extracellular loop of the human beta-adrenergic receptor. Clin Exp Immunol 2006, 143: 209-215
21. 1- adrenoreceptor peptide induces cardiomyopathy-like changes in rabbit hearts. Chin Med J 2002, 115: 170-174
22. 1-adrenergic receptor function, autoimmunity, and pathogenesis of dilated cardiomyopathy. Trends Cardiovasc Med 2006, 16: 20-24
23. 1-adrenergic receptor transgenic mice. Proc Natl Acad Sci USA 1999, 96: 7059-7064
24. Wallukat G. The β-adrenergic receptors. Herz 2002, 27: 683-690