A complex, four-way variant t(15;17) in acute promyelocytic leukemia

Cancer Genetics and Cytogenetics

Volumn 167, Issue 2, 2006, Pages 168-171

  Yoo, Soo Jin ^a   Seo, Eul Ju ^b   Lee, Jae Hoon ^c   Seo, Yiel Hea ^c   Park, Pil Whan ^c   Ahn, Jeong Yeal ^c  

^a Inje University College of Medicine   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

^c Gachon University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; PROMYELOCYTIC LEUKEMIA PROTEIN; RETINOIC ACID; ANTINEOPLASTIC AGENT;

ADULT; ANAMNESIS; ARTICLE; BLEEDING; BLOOD CELL COUNT; BONE MARROW BIOPSY; BONE MARROW CELL; CASE REPORT; CHROMOSOME ANALYSIS; CHROMOSOME TRANSLOCATION 10; CHROMOSOME TRANSLOCATION 15; CHROMOSOME TRANSLOCATION 17; CHROMOSOME TRANSLOCATION 22; CLINICAL FEATURE; DNA PROBE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE FUSION; HUMAN; LEUKOCYTE; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; REMISSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THROMBOCYTE; TOOTH EXTRACTION; CELL CULTURE; CHROMOSOME 15; CHROMOSOME 17; GENE TRANSLOCATION; GENETICS; MIDDLE AGED; TREATMENT OUTCOME; ULTRASTRUCTURE;

ANTINEOPLASTIC AGENTS; BONE MARROW CELLS; CELLS, CULTURED; CHROMOSOMES, HUMAN, PAIR 15; CHROMOSOMES, HUMAN, PAIR 17; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, PROMYELOCYTIC, ACUTE; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSLOCATION, GENETIC; TREATMENT OUTCOME; TRETINOIN;

EID: 33746199926     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2005.12.006     Document Type: Article

References (30)

1. Rowley J.D., Golomb H.M., and Dougherty C. 15/17 translocation, a consistent chromosomal change in acute promyelocytic leukaemia. Lancet i 8010 (1977) 549-550
2. de The H., Chomienne C., Lanotte M., Degos L., and Dejean A. The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus. Nature 347 (1990) 558-561
3. Melnick A., and Licht J.D. Deconstructing a disease: RARα, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia. Blood 93 (1999) 3167-3215
4. Wan T.S., Chim C.S., So C.K., Chan L.C., and Ma S.K. Complex variant 15;17 translocations in acute promyelocytic leukemia: a case report and review of three-way translocations. Cancer Genet Cytogenet 111 (1999) 139-143
5. Liu S., Li Q., Pang W., Bo L., Qin S., Liu X., Teng Q., Qian L., and Wang J. A new complex variant t(4;15;17) in acute promyelocytic leukemia: fluorescence in situ hybridization confirmation and literature review. Cancer Genet Cytogenet 130 (2001) 33-37
6. Lo Coco F., Diverio D., D'Adamo F., Avvisati G., Alimena G., Nanni M., et al. PML/RAR-alpha rearrangement in acute promyelocytic leukaemias apparently lacking the t(15;17) translocation. Eur J Haematol 48 (1992) 173-176
7. ISCN 1995: an international system for human cytogenetic nomenclature (1995). Mitelman F, editor. Basel: S. Karger, 1995.
8. Chomczynski P., and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162 (1987) 156-159
9. Miller Jr. W.H., Kakizuka A., Frankel S.R., Warrell Jr. R.P., DeBlasio A., Levine K., Evans R.M., and Dmitrovsky E. Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor α clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia. Proc Natl Acad Sci U S A 89 (1992) 2694-2698
10. Galieni P., Marotta G., Vessichelli F., Diverio D., Minoletti F., Bucalossi A., Lo Coco F., and Lauria F. Variant t(1;15;17)(q23;q22;q23) in a case of acute promyelocytic leukemia. Leukemia 10 (1996) 1658-1661
11. Osella P., Wyandt H., Vosburgh E., and Milunsky A. Report of a variant t(1;15;17)(p36;q22;q21.1) in a patient with acute promyelocytic leukemia. Cancer Genet Cytogenet 57 (1991) 201-207
12. Park J.P., and Fairweather R.B. Complex t(1;15;17) in acute promyelocytic leukemia with duplication of RARα and PML sequences. Cancer Genet Cytogenet 89 (1996) 52-56
13. Brunel V., Lafage-Pochitaloff M., Alcalay M., Pelicci P.G., and Birg F. Variant and masked translocations in acute promyelocytic leukemia. Leuk Lymphoma 22 (1996) 221-228
14. Bjerrum O.W., Philip P., Pressler T., and Tygstrup I. Acute promyelocytic leukemia with t(15;17) and t(2;17;15). Cancer Genet Cytogenet 28 (1987) 107-111
15. Bernstein R., Mendelow B., Pinto M.R., Morcom G., and Bezwoda W. Complex translocations involving chromosomes 15 and 17 in acute promyelocytic leukaemia. Br J Haematol 46 (1980) 311-314
16. McKinney C.D., Golden W.L., Gemma N.W., Swerdlow S.H., and Williams M.E. RARA and PML gene rearrangements in acute promyelocytic leukemia with complex translocations and atypical features. Genes Chromosomes Cancer 9 (1994) 49-56
17. Huret J.L., Couet D., Guilhot F., Brizard A., and Tanzer J. A two-step t(4;der(15)) t(15;17) complex translocation in an acute promyelocytic leukaemia and review of the literature. Leuk Res 11 (1987) 761-765
18. Berger R., Flandrin G., Bernheim A., Le Coniat M., Vecchione D., Pacot A., Derre J., Daniel M.T., Valensi F., Sigaux F., et al. Cytogenetic studies on 519 consecutive de novo acute nonlymphocytic leukemias. Cancer Genet Cytogenet 29 (1987) 9-21
19. Chen Z., Morgan R., Stone J.F., and Sandberg A.A. Identification of complex t(15;17) in APL by FISH. Cancer Genet Cytogenet 72 (1994) 73-74
20. Casula L., Archidiacono N., Grazia Pau M., Addis M., Mura R., Galanello R., Biddau P., Cao A., and Nucaro A. Cytogenetic and molecular characterization of a variant translocation associated with acute promyelocytic leukemia and involving chromosomes 11, 15 and 17. Leukemia 10 (1996) 1655-1657
21. Saitoh K., Miura I., Kobayashi Y., Kume M., Utsumi S., Takahashi N., Hatano Y., Nimura T., Hashimoto K., Takahashi S., and Miura A.B. A new variant translocation of t(15;17) in a patient with acute promyelocytic leukemia (M3): t(15;19;17)(q22;p13;q12). Cancer Genet Cytogenet 102 (1998) 15-18
22. Yamamoto K., Hamaguchi H., Nagata K., Kobayashi M., Takashima T., and Taniwaki M. A new complex translocation (15;20;17)(q22;p13;q21) in acute promyelocytic leukemia. Cancer Genet Cytogenet 101 (1998) 89-94
23. Zaccaria A., Testoni M., Martinelli G., Pelliconi S., Buzzi M., Farbegoli P., Naldi S., Salvucci M., and Tura S. Four-chromosomes complex translocations in acute promyelocytic leukemia: description of two cases. Eur J Haematol 52 (1994) 129-133
24. Callen D.F., Dale B.M., Sage R.E., and Ford J.H. A complex translocation in acute promyelocytic leukemia. Cancer Genet Cytogenet 16 (1985) 45-48
25. Grimwade D., Biondi A., Mozziconacci M.J., Hagemeijer A., Berger R., Neat M., Howe K., Dastugue N., Jansen J., Radford-Weiss I., Lo Coco F., Lessard M., Hernandez J.M., Delabesse E., Head D., Liso V., Sainty D., Flandrin G., Solomon E., Birg F., and Lafage-Pochitaloff M. Groupe Français de Cytogénétique Hématologique; Groupe Français de Hématologie Cellulaire; UK Cancer Cytogenetics Group; and BIOMED 1 European Community-Concerted Action "Molecular Cytogenetic Diagnosis in Haematological Malignancies." Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): results of the European Working Party. Blood 96 (2000) 1297-1308
26. Hiorns L.R., Swansbury G.J., and Catovsky D. An eight-way variant t(15;17) in acute promyelocytic leukemia elucidated using fluorescence in situ hybridization. Cancer Genet Cytogenet 83 (1995) 136-139
27. Eclache V., Viguie F., Frocrain C., Cassinat B., Chomienne C., Cymbalista F., et al. A new variant t(6;15;17)(q25;q22;q21) in acute promyelocytic leukemia: fluorescence in situ hybridization confirmation. Cancer Genet Cytogenet 159 (2005) 69-73
28. Misawa S., Lee E., Schiffer C.A., Liu Z., and Testa J.R. Association of the translocation (15;17) with malignant proliferation of promyelocytes in acute leukemia and chronic myelogenous leukemia at blastic crisis. Blood 67 (1986) 270-274
29. Ogawa S., Mitani K., Sato Y., Sugimoto K., Toyoshima H., Mano H., Takaku F., Yazaki Y., and Hirai H. Detection of the PML/RARα fusion gene in acute promyelocytic leukemia with a complex translocation involving chromosomes 15, 17, and 18. Cancer Genet Cytogenet 69 (1993) 113-117
30. Calabrese G., Min T., Stuppia L., Powles R., Swansbury J.G., Morizio E., Peila R., Donti E., Fioritoni G., and Palka G. Complex chromosome translocations of standard t(8;21) and t(15;17) arise from a two-step mechanism as evidenced by fluorescence in situ hybridization analysis. Cancer Genet Cytogenet 91 (1996) 40-45