메뉴 건너뛰기




Volumn 20, Issue 8, 2006, Pages 1377-1384

Differential expression of p73 isoforms in relation to drug resistance in childhood T-lineage acute lymphoblastic leukaemia

Author keywords

Drug resistance; Outcome; p73; T ALL

Indexed keywords

DAUNORUBICIN; DNA; ISOPROTEIN; MESSENGER RNA; PREDNISOLONE SODIUM PHOSPHATE; PROTEIN P73; RNA; VINCRISTINE SULFATE;

EID: 33746106468     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404288     Document Type: Article
Times cited : (21)

References (48)
  • 1
    • 0030812331 scopus 로고    scopus 로고
    • Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
    • Kaghad M, Bonnet H, Yang A, Creancier L, Biscan JC, Valent A et al. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 1997; 90: 809-819.
    • (1997) Cell , vol.90 , pp. 809-819
    • Kaghad, M.1    Bonnet, H.2    Yang, A.3    Creancier, L.4    Biscan, J.C.5    Valent, A.6
  • 3
    • 0032990811 scopus 로고    scopus 로고
    • Additional complexity in p73: Induction by mitogens in lymphoid cells and identification of two new splicing variants epsilon and zeta
    • De Laurenzi VD, Catani MV, Terrinoni A, Corazzari M, Melino G, Costanzo A et al. Additional complexity in p73: Induction by mitogens in lymphoid cells and identification of two new splicing variants epsilon and zeta. Cell Death Differ 1999; 6: 389-390.
    • (1999) Cell Death Differ , vol.6 , pp. 389-390
    • De Laurenzi, V.D.1    Catani, M.V.2    Terrinoni, A.3    Corazzari, M.4    Melino, G.5    Costanzo, A.6
  • 4
    • 0033517321 scopus 로고    scopus 로고
    • New p73 variants with altered C-terminal structures shave varied transcriptional activities
    • Ueda Y, Hijikata M, Takagi S, Chiba T, Shimotohno K. New p73 variants with altered C-terminal structures shave varied transcriptional activities. Oncogene 1999; 18: 4993-4998.
    • (1999) Oncogene , vol.18 , pp. 4993-4998
    • Ueda, Y.1    Hijikata, M.2    Takagi, S.3    Chiba, T.4    Shimotohno, K.5
  • 5
    • 0036468249 scopus 로고    scopus 로고
    • Possible oncogenic potential of DeltaNp73: A newly identified isoform of human p73
    • Ishimoto O, Kawahara C, Enjo K, Obinata M, Nukiwa T, Ikawa S. Possible oncogenic potential of DeltaNp73: A newly identified isoform of human p73. Cancer Res 2002; 62: 636-641.
    • (2002) Cancer Res , vol.62 , pp. 636-641
    • Ishimoto, O.1    Kawahara, C.2    Enjo, K.3    Obinata, M.4    Nukiwa, T.5    Ikawa, S.6
  • 6
    • 0032533514 scopus 로고    scopus 로고
    • The potential tumor suppressor p73 differentially regulates cellular p53 target genes
    • Zhu J, Jiang J, Zhou W, Chen X. The potential tumor suppressor p73 differentially regulates cellular p53 target genes. Cancer Res 1998; 58: 5061-5065.
    • (1998) Cancer Res , vol.58 , pp. 5061-5065
    • Zhu, J.1    Jiang, J.2    Zhou, W.3    Chen, X.4
  • 7
    • 0034628491 scopus 로고    scopus 로고
    • p73 transcriptional activity increases upon cooperation between its spliced forms
    • Alarcon-Vargas D, Fuchs SY, Deb S, Ronai Z. p73 transcriptional activity increases upon cooperation between its spliced forms. Oncogene 2000; 19: 831-835.
    • (2000) Oncogene , vol.19 , pp. 831-835
    • Alarcon-Vargas, D.1    Fuchs, S.Y.2    Deb, S.3    Ronai, Z.4
  • 8
    • 0035875357 scopus 로고    scopus 로고
    • Transcriptional activities of p73 splicing variants are regulated by intervariant association
    • Ueda Y, Hijikata M, Takagi S, Chiba T, Shimotohno K. Transcriptional activities of p73 splicing variants are regulated by intervariant association. Biochem J 2001; 356: 859-866.
    • (2001) Biochem J , vol.356 , pp. 859-866
    • Ueda, Y.1    Hijikata, M.2    Takagi, S.3    Chiba, T.4    Shimotohno, K.5
  • 9
    • 0037077721 scopus 로고    scopus 로고
    • Differential regulation of transcription and induction of programmed cell death by human p53-family members p63 and p73
    • Dietz S, Rother K, Bamberger C, Schmale H, Mossner J, Engeland K. Differential regulation of transcription and induction of programmed cell death by human p53-family members p63 and p73. FEBS Lett 2002; 525: 93-99.
    • (2002) FEBS Lett , vol.525 , pp. 93-99
    • Dietz, S.1    Rother, K.2    Bamberger, C.3    Schmale, H.4    Mossner, J.5    Engeland, K.6
  • 11
    • 0037134475 scopus 로고    scopus 로고
    • Transactivation-deficient Delta TA-p73 inhibits p53 by direct competition for DNA binding: Implications for tumorigenesis
    • Stiewe T, Theseling CC, Putzer BM. Transactivation-deficient Delta TA-p73 inhibits p53 by direct competition for DNA binding: Implications for tumorigenesis. J Biol Chem 2002; 277: 14177-14185.
    • (2002) J Biol Chem , vol.277 , pp. 14177-14185
    • Stiewe, T.1    Theseling, C.C.2    Putzer, B.M.3
  • 13
    • 0037130473 scopus 로고    scopus 로고
    • p53 induces the expression of its antagonist p73 Delta N, establishing an autoregulatory feedback loop
    • Kartasheva NN, Contente A, Lenz-Stoppler C, Roth J, Dobbelstein M. p53 induces the expression of its antagonist p73 Delta N, establishing an autoregulatory feedback loop. Oncogene 2002; 21: 4715-4727.
    • (2002) Oncogene , vol.21 , pp. 4715-4727
    • Kartasheva, N.N.1    Contente, A.2    Lenz-Stoppler, C.3    Roth, J.4    Dobbelstein, M.5
  • 14
    • 0037161921 scopus 로고    scopus 로고
    • DN-p73 is activated after DNA damage in a p53-dependent manner to regulate p53-induced cell cycle arrest
    • Vossio S, Palescandolo E, Pediconi N, Moretti F, Balsano C, Levrero M et al. DN-p73 is activated after DNA damage in a p53-dependent manner to regulate p53-induced cell cycle arrest. Oncogene 2002; 21: 3796-3803.
    • (2002) Oncogene , vol.21 , pp. 3796-3803
    • Vossio, S.1    Palescandolo, E.2    Pediconi, N.3    Moretti, F.4    Balsano, C.5    Levrero, M.6
  • 16
    • 17744386129 scopus 로고    scopus 로고
    • Transactivation-deficient p73alpha (p73Deltaexon2) inhibits apoptosis and competes with p53
    • Fillippovich I, Sorokina N, Gatei M, Haupt Y, Hobson K, Moallem E et al. Transactivation-deficient p73alpha (p73Deltaexon2) inhibits apoptosis and competes with p53. Oncogene 2001; 20: 514-522.
    • (2001) Oncogene , vol.20 , pp. 514-522
    • Fillippovich, I.1    Sorokina, N.2    Gatei, M.3    Haupt, Y.4    Hobson, K.5    Moallem, E.6
  • 18
    • 0842269242 scopus 로고    scopus 로고
    • p53 family members and chemoresistance in cancer: What we know and what we need to know
    • Gasco M, Crook T. p53 family members and chemoresistance in cancer: What we know and what we need to know. Drug Resist Updat 2003; 6: 323-328.
    • (2003) Drug Resist Updat , vol.6 , pp. 323-328
    • Gasco, M.1    Crook, T.2
  • 19
    • 2342446704 scopus 로고    scopus 로고
    • p73-mediated chemosensitivity: A preferential target of oncogenic mutant p53
    • Strano S, Blandino G. p73-mediated chemosensitivity: A preferential target of oncogenic mutant p53. Cell Cycle 2003; 2: 348-349.
    • (2003) Cell Cycle , vol.2 , pp. 348-349
    • Strano, S.1    Blandino, G.2
  • 20
    • 4344639696 scopus 로고    scopus 로고
    • Family feud in chemosensitvity: p73 and mutant p53
    • Irwin MS. Family feud in chemosensitvity: P73 and mutant p53. Cell Cycle 2004; 3: 319-323.
    • (2004) Cell Cycle , vol.3 , pp. 319-323
    • Irwin, M.S.1
  • 21
    • 10744230945 scopus 로고    scopus 로고
    • p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis
    • Bergamaschi D, Gasco M, Hiller L, Sullivan A, Syed N, Trigiante G et al. p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis. Cancer Cell 2003; 3: 387-402.
    • (2003) Cancer Cell , vol.3 , pp. 387-402
    • Bergamaschi, D.1    Gasco, M.2    Hiller, L.3    Sullivan, A.4    Syed, N.5    Trigiante, G.6
  • 22
    • 0031717981 scopus 로고    scopus 로고
    • Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia - Implications for treatment of infants
    • Pieters R, den Boer ML, Durian M, Janka G, Schmiegelow K, Kaspers GJ et al. Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia - implications for treatment of infants. Leukemia 1998; 12: 1344-1348.
    • (1998) Leukemia , vol.12 , pp. 1344-1348
    • Pieters, R.1    den Boer, M.L.2    Durian, M.3    Janka, G.4    Schmiegelow, K.5    Kaspers, G.J.6
  • 23
    • 0034762778 scopus 로고    scopus 로고
    • Analysis of TP53 mutations in relapsed childhood acute lymphoblastic leukemia
    • Gump J, McGavran L, Wei Q, Hunger SP. Analysis of TP53 mutations in relapsed childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol 2001; 23: 416-419.
    • (2001) J Pediatr Hematol Oncol , vol.23 , pp. 416-419
    • Gump, J.1    McGavran, L.2    Wei, Q.3    Hunger, S.P.4
  • 24
    • 0032932735 scopus 로고    scopus 로고
    • Alterations of the p53, p21, p16, p15 and RAS genes in childhood T-cell acute lymphoblastic leukemia
    • Kawamura M, Ohnishi H, Guo SX, Sheng XM, Minegishi M, Hanada R et al. Alterations of the p53, p21, p16, p15 and RAS genes in childhood T-cell acute lymphoblastic leukemia. Leuk Res 1999; 23: 115-126.
    • (1999) Leuk Res , vol.23 , pp. 115-126
    • Kawamura, M.1    Ohnishi, H.2    Guo, S.X.3    Sheng, X.M.4    Minegishi, M.5    Hanada, R.6
  • 25
    • 0037220020 scopus 로고    scopus 로고
    • TP53 in hematological cancer: Low incidence of mutations with significant clinical relevance
    • Peller S, Rotter V. TP53 in hematological cancer: Low incidence of mutations with significant clinical relevance. Hum Mutat 2003; 21: 277-284.
    • (2003) Hum Mutat , vol.21 , pp. 277-284
    • Peller, S.1    Rotter, V.2
  • 26
    • 0033199166 scopus 로고    scopus 로고
    • Distinct expression patterns of the p53-homologue p73 in malignant and normal hematopoiesis assessed by a novel real-time reverse transcription-polymerase chain reaction assay and protein analysis
    • Peters UR, Tschan MP, Kreuzer KA, Baskaynak G, Lass U, Tobler A et al. Distinct expression patterns of the p53-homologue p73 in malignant and normal hematopoiesis assessed by a novel real-time reverse transcription-polymerase chain reaction assay and protein analysis. Cancer Res 1999; 59: 4233-4236.
    • (1999) Cancer Res , vol.59 , pp. 4233-4236
    • Peters, U.R.1    Tschan, M.P.2    Kreuzer, K.A.3    Baskaynak, G.4    Lass, U.5    Tobler, A.6
  • 28
    • 8844270933 scopus 로고    scopus 로고
    • Analysis of p73 expression pattern in acute myeloid leukemias: Lack of DeltaN-p73 expression is a frequent feature of acute promyelocytic leukemia
    • Rizzo MG, Giombini E, Diverio D, Vignetti M, Sacchi A, Testa U et al. Analysis of p73 expression pattern in acute myeloid leukemias: Lack of DeltaN-p73 expression is a frequent feature of acute promyelocytic leukemia. Leukemia 2004; 18: 1804-1809.
    • (2004) Leukemia , vol.18 , pp. 1804-1809
    • Rizzo, M.G.1    Giombini, E.2    Diverio, D.3    Vignetti, M.4    Sacchi, A.5    Testa, U.6
  • 30
    • 0034899043 scopus 로고    scopus 로고
    • Overexpression of the p73 gene is a novel finding in high-risk B-cell chronic lymphocytic leukemia
    • Novak U, Grob TJ, Baskaynak G, Peters UR, Aebi S, Zwahlen D et al. Overexpression of the p73 gene is a novel finding in high-risk B-cell chronic lymphocytic leukemia. Ann Oncol 2001; 12: 981-986.
    • (2001) Ann Oncol , vol.12 , pp. 981-986
    • Novak, U.1    Grob, T.J.2    Baskaynak, G.3    Peters, U.R.4    Aebi, S.5    Zwahlen, D.6
  • 31
    • 11844289035 scopus 로고    scopus 로고
    • Alteration of p73 in pediatric de novo acute lymphoblastic leukemia
    • Sahu GR, Das BR. Alteration of p73 in pediatric de novo acute lymphoblastic leukemia. Biochem Biophys Res Commun 2005; 327: 750-755.
    • (2005) Biochem Biophys Res Commun , vol.327 , pp. 750-755
    • Sahu, G.R.1    Das, B.R.2
  • 32
    • 0033600235 scopus 로고    scopus 로고
    • p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
    • Yuan ZM, Shioya H, Ishiko T, Sun X, Gu J, Huang YY et al. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature 1999; 399: 814-817.
    • (1999) Nature , vol.399 , pp. 814-817
    • Yuan, Z.M.1    Shioya, H.2    Ishiko, T.3    Sun, X.4    Gu, J.5    Huang, Y.Y.6
  • 33
    • 0028032922 scopus 로고
    • Mononuclear cells contaminating acute lymphoblastic leukaemic samples tested for cellular drug resistance using the methyl-thiazol-tetrazolium assay
    • Kaspers GJ, Veerman AJ, Pieters R, Broekema GJ, Huismans DR, Kazemier KM et al. Mononuclear cells contaminating acute lymphoblastic leukaemic samples tested for cellular drug resistance using the methyl-thiazol-tetrazolium assay. Br J Cancer 1994; 70: 1047-1052.
    • (1994) Br J Cancer , vol.70 , pp. 1047-1052
    • Kaspers, G.J.1    Veerman, A.J.2    Pieters, R.3    Broekema, G.J.4    Huismans, D.R.5    Kazemier, K.M.6
  • 34
    • 0141799965 scopus 로고    scopus 로고
    • Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia
    • Den Boer ML, Harms DO, Pieters R, Kazemier KM, Gobel U, Korholz D et al. Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia. J Clin Oncol 2003; 21: 3262-3268.
    • (2003) J Clin Oncol , vol.21 , pp. 3262-3268
    • Den Boer, M.L.1    Harms, D.O.2    Pieters, R.3    Kazemier, K.M.4    Gobel, U.5    Korholz, D.6
  • 35
    • 0037441744 scopus 로고    scopus 로고
    • Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia
    • Stam RW, den Boer ML, Meijerink JP, Ebus ME, Peters GJ, Noordhuis P et al. Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia. Blood 2003; 101: 1270-1276.
    • (2003) Blood , vol.101 , pp. 1270-1276
    • Stam, R.W.1    den Boer, M.L.2    Meijerink, J.P.3    Ebus, M.E.4    Peters, G.J.5    Noordhuis, P.6
  • 36
    • 0035003174 scopus 로고    scopus 로고
    • A novel method to compensate for different amplification efficiencies between patient DNA samples in quantitative real-time PCR
    • Meijerink J, Mandigers C, van de Locht L, Tonnissen E, Goodsaid F, Raemaekers J. A novel method to compensate for different amplification efficiencies between patient DNA samples in quantitative real-time PCR. J Mol Diagn 2001; 3: 55-61.
    • (2001) J Mol Diagn , vol.3 , pp. 55-61
    • Meijerink, J.1    Mandigers, C.2    van de Locht, L.3    Tonnissen, E.4    Goodsaid, F.5    Raemaekers, J.6
  • 37
    • 0035900819 scopus 로고    scopus 로고
    • p73 is over-expressed in vulval cancer principally as the Delta 2 isoform
    • O'Nions J, Brooks LA, Sullivan A, Bell A, Dunne B, Rozycka M et al. p73 is over-expressed in vulval cancer principally as the Delta 2 isoform. Br J Cancer 2001; 85: 1551-1556.
    • (2001) Br J Cancer , vol.85 , pp. 1551-1556
    • O'Nions, J.1    Brooks, L.A.2    Sullivan, A.3    Bell, A.4    Dunne, B.5    Rozycka, M.6
  • 39
    • 0037119631 scopus 로고    scopus 로고
    • DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors
    • Zaika AI, Slade N, Erster SH, Sansome C, Joseph TW, Pearl M et al. DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors. J Exp Med 2002; 196: 765-780.
    • (2002) J Exp Med , vol.196 , pp. 765-780
    • Zaika, A.I.1    Slade, N.2    Erster, S.H.3    Sansome, C.4    Joseph, T.W.5    Pearl, M.6
  • 41
    • 0037041392 scopus 로고    scopus 로고
    • p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
    • Flores ER, Tsai KY, Crowley D, Sengupta S, Yang A, McKeon F et al. p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature 2002; 416: 560-564.
    • (2002) Nature , vol.416 , pp. 560-564
    • Flores, E.R.1    Tsai, K.Y.2    Crowley, D.3    Sengupta, S.4    Yang, A.5    McKeon, F.6
  • 42
    • 0036005908 scopus 로고    scopus 로고
    • Expression of DeltaNp73 is a molecular marker for adverse outcome in neuroblastoma patients
    • Casciano I, Mazzocco K, Boni L, Pagnan G, Banelli B, Allemanni G et al. Expression of DeltaNp73 is a molecular marker for adverse outcome in neuroblastoma patients. Cell Death Differ 2002; 9: 246-251.
    • (2002) Cell Death Differ , vol.9 , pp. 246-251
    • Casciano, I.1    Mazzocco, K.2    Boni, L.3    Pagnan, G.4    Banelli, B.5    Allemanni, G.6
  • 44
    • 0034009374 scopus 로고    scopus 로고
    • Lack of p73 expression in mature B-ALL and identification of three new splicing variants restricted to pre B and C-ALL indicate a role of p73 in B cell ALL differentiation
    • Scaruffi P, Casciano I, Masiero L, Basso G, Romani M, Tonini GP. Lack of p73 expression in mature B-ALL and identification of three new splicing variants restricted to pre B and C-ALL indicate a role of p73 in B cell ALL differentiation. Leukemia 2000; 14: 518-519.
    • (2000) Leukemia , vol.14 , pp. 518-519
    • Scaruffi, P.1    Casciano, I.2    Masiero, L.3    Basso, G.4    Romani, M.5    Tonini, G.P.6
  • 45
    • 0033179665 scopus 로고    scopus 로고
    • Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation
    • Kawano S, Miller CW, Gombart AF, Bartram CR, Matsuo Y, Asou H et al. Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation. Blood 1999; 94: 1113-1120.
    • (1999) Blood , vol.94 , pp. 1113-1120
    • Kawano, S.1    Miller, C.W.2    Gombart, A.F.3    Bartram, C.R.4    Matsuo, Y.5    Asou, H.6
  • 46
    • 0035028445 scopus 로고    scopus 로고
    • Loss of p73 gene expression in lymphoid leukemia cell lines is associated with hypermethylation
    • Liu M, Taketani T, Li R, Takita J, Taki T, Yang HW et al. Loss of p73 gene expression in lymphoid leukemia cell lines is associated with hypermethylation. Leuk Res 2001; 25: 441-447.
    • (2001) Leuk Res , vol.25 , pp. 441-447
    • Liu, M.1    Taketani, T.2    Li, R.3    Takita, J.4    Taki, T.5    Yang, H.W.6
  • 47
    • 0033565514 scopus 로고    scopus 로고
    • Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5′ CpG island methylation
    • Corn PG, Kuerbitz SJ, van Noesel MM, Esteller M, Compitello N, Baylin SB et al. Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5′ CpG island methylation. Cancer Res 1999; 59: 3352-3356.
    • (1999) Cancer Res , vol.59 , pp. 3352-3356
    • Corn, P.G.1    Kuerbitz, S.J.2    van Noesel, M.M.3    Esteller, M.4    Compitello, N.5    Baylin, S.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.